Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 66046741

GI number: 66046741

Start: 4186583

End: 4187956

Strand: Direct

Name: qseC [H]

Synonym: Psyr_3512

Alternate gene names: 66046741

Gene position: 4186583-4187956 (Clockwise)

Preceding gene: 66046740

Following gene: 66046744

Centisome position: 68.7

GC content: 63.68

Gene sequence:

>1374_bases
ATGACCTCGGTACGCGCGCGCATTCTGGTCCCGGTGCTGATGCTGTTGCTGCTCGGCGACCTGACCATCAGCCTGCTCGC
CCTGCGCGACAGCCATCACGAAATCGAAGAAGTCTACGATGCACAGCTGGCCCAAAGCGCGCGCCTGCTGCAAGGCGTAC
TGCATCAGCGCGCAGCGGGTGAGCAAGACCTCGACAAGCTGTATCAGGCGTTCGATCAGGCCATGAGCCGGGTCGGCACC
AGTGGCGTGGCCCATCCCTACGAAACCCGGCTGACCTTTCAGGTCTGGCGCACCTCGGGCGAGCTGCTGGTGCGCTCGGC
CGAAGCCCCGCTGCTCAGTGCACCTCCGGCAACCGAAGGCTCCCATGATCTGGTCGAGAACGGCCACGAGTGGTGCGGCT
TTCTCCTCGCCGATCCGCAGCAGGGTTTTCTGATCTGGGTGGGTGAGCGCGATGACGTACGCCAGGACCTGATTCAGCGC
ATTGTCAGTCACACGCTGTGGCCGACGCTGATCGGTGTGCCGCTGCTGGTGGTGGCGATCTGGCTGGCCATCGGCTGGGG
CCTGCGCCCGCTGCAAGCGATGGCCAGAGTCATCCGCAAGCGCGATGCCGAAAGCCTCGAACCGCTTGCTGTAACGCCCC
TGCCCAAAGAGCTGGAGCCCATGCAGTACGCGCTCAACCGCCTGCTGACTCAGATCGAGAGTGTGCTGGAACGCGAGCGA
CGCTTCATCGCTGACGCGGCCCACGAACTGCGCACACCACTGACCATCCTGCGCATCCACGCGCAGAACGCGCGCCAGGC
CGAAACCCCGGAGCAACGCCTGGAAGCACTGGATTTCCTTGTGCATGGCGTCGACCGCGCCGCCCGCCTGGCCAGTCAGT
TATTGACCATGGCACGCCTGGAACCGCGCCTTGAAGTCAGCCAGTTACAGACCTTCGAGCTGAACACGCTGGTACGCGAG
GAAATGGCCGAACTCACGCCGCTGGCCCTGGAGAAGCGCGTCGATCTGGTGTTCGAGGAAGGCGAGGATTGCGTGATCCG
CAGCGACCCGGCAGCCATCACCATTGCCCTGCAGAACCTGCTGACCAATGCGCTGAATTTCGCCCCGACCGCCAGCGAGA
TACGCGTCGCCCTGCACACCCAGGAAGATGGCAGCGCGCATTTGTCAGTCGAAGACGCAGGGCCGGGTATCGACGAACAA
CAGAAGGCGCGCCTCTTCGAACGCTTTTACAGTCAGGGTCACAGCAATGGCGCAGGGCTAGGGCTGGCGATCGTCGACAT
GATCGTGCGCAAACTGGAAAGCAGCCTGCACCTGCGCAACTCGGCGCAGGGCGGACTGTGTGCAGAGCTGCGCATCAAGA
GCAGGACGAGCTGA

Upstream 100 bases:

>100_bases
GCAACACGCTGGAGGTACTGATTCACAACCTGCGCAAGAAACTGTCCACCGAGCTGATCCGCACCGTGCGCGGCGTCGGT
TACCTGCTGGAGCTCAAGGC

Downstream 100 bases:

>100_bases
ACCCGCTCGGTTCAAAGCACCACGCGCAGGCATTGCCCGGCGTGATACAGGGTGAAACCCGTGTCGTAGGCGAGGCTGCG
CAGCGAACTGCCCGAGACCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTSVRARILVPVLMLLLLGDLTISLLALRDSHHEIEEVYDAQLAQSARLLQGVLHQRAAGEQDLDKLYQAFDQAMSRVGT
SGVAHPYETRLTFQVWRTSGELLVRSAEAPLLSAPPATEGSHDLVENGHEWCGFLLADPQQGFLIWVGERDDVRQDLIQR
IVSHTLWPTLIGVPLLVVAIWLAIGWGLRPLQAMARVIRKRDAESLEPLAVTPLPKELEPMQYALNRLLTQIESVLERER
RFIADAAHELRTPLTILRIHAQNARQAETPEQRLEALDFLVHGVDRAARLASQLLTMARLEPRLEVSQLQTFELNTLVRE
EMAELTPLALEKRVDLVFEEGEDCVIRSDPAAITIALQNLLTNALNFAPTASEIRVALHTQEDGSAHLSVEDAGPGIDEQ
QKARLFERFYSQGHSNGAGLGLAIVDMIVRKLESSLHLRNSAQGGLCAELRIKSRTS

Sequences:

>Translated_457_residues
MTSVRARILVPVLMLLLLGDLTISLLALRDSHHEIEEVYDAQLAQSARLLQGVLHQRAAGEQDLDKLYQAFDQAMSRVGT
SGVAHPYETRLTFQVWRTSGELLVRSAEAPLLSAPPATEGSHDLVENGHEWCGFLLADPQQGFLIWVGERDDVRQDLIQR
IVSHTLWPTLIGVPLLVVAIWLAIGWGLRPLQAMARVIRKRDAESLEPLAVTPLPKELEPMQYALNRLLTQIESVLERER
RFIADAAHELRTPLTILRIHAQNARQAETPEQRLEALDFLVHGVDRAARLASQLLTMARLEPRLEVSQLQTFELNTLVRE
EMAELTPLALEKRVDLVFEEGEDCVIRSDPAAITIALQNLLTNALNFAPTASEIRVALHTQEDGSAHLSVEDAGPGIDEQ
QKARLFERFYSQGHSNGAGLGLAIVDMIVRKLESSLHLRNSAQGGLCAELRIKSRTS
>Mature_456_residues
TSVRARILVPVLMLLLLGDLTISLLALRDSHHEIEEVYDAQLAQSARLLQGVLHQRAAGEQDLDKLYQAFDQAMSRVGTS
GVAHPYETRLTFQVWRTSGELLVRSAEAPLLSAPPATEGSHDLVENGHEWCGFLLADPQQGFLIWVGERDDVRQDLIQRI
VSHTLWPTLIGVPLLVVAIWLAIGWGLRPLQAMARVIRKRDAESLEPLAVTPLPKELEPMQYALNRLLTQIESVLERERR
FIADAAHELRTPLTILRIHAQNARQAETPEQRLEALDFLVHGVDRAARLASQLLTMARLEPRLEVSQLQTFELNTLVREE
MAELTPLALEKRVDLVFEEGEDCVIRSDPAAITIALQNLLTNALNFAPTASEIRVALHTQEDGSAHLSVEDAGPGIDEQQ
KARLFERFYSQGHSNGAGLGLAIVDMIVRKLESSLHLRNSAQGGLCAELRIKSRTS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=455, Percent_Identity=29.2307692307692, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1790551, Length=301, Percent_Identity=30.5647840531561, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786783, Length=318, Percent_Identity=28.6163522012579, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=30.7936507936508, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=26.9896193771626, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=30.4347826086957, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=27.6150627615063, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788549, Length=190, Percent_Identity=32.1052631578947, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=25.8196721311475, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=28.4518828451883, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789808, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.4642857142857, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787374, Length=279, Percent_Identity=25.089605734767, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=24.6710526315789, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50901; Mature: 50770

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVRARILVPVLMLLLLGDLTISLLALRDSHHEIEEVYDAQLAQSARLLQGVLHQRAAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQDLDKLYQAFDQAMSRVGTSGVAHPYETRLTFQVWRTSGELLVRSAEAPLLSAPPATEG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCHHEEEECCCCCCCCCCCCCC
SHDLVENGHEWCGFLLADPQQGFLIWVGERDDVRQDLIQRIVSHTLWPTLIGVPLLVVAI
CHHHHHCCHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAIGWGLRPLQAMARVIRKRDAESLEPLAVTPLPKELEPMQYALNRLLTQIESVLERER
HHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHH
RFIADAAHELRTPLTILRIHAQNARQAETPEQRLEALDFLVHGVDRAARLASQLLTMARL
HHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPRLEVSQLQTFELNTLVREEMAELTPLALEKRVDLVFEEGEDCVIRSDPAAITIALQNL
CCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
LTNALNFAPTASEIRVALHTQEDGSAHLSVEDAGPGIDEQQKARLFERFYSQGHSNGAGL
HHHHHCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCH
GLAIVDMIVRKLESSLHLRNSAQGGLCAELRIKSRTS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TSVRARILVPVLMLLLLGDLTISLLALRDSHHEIEEVYDAQLAQSARLLQGVLHQRAAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQDLDKLYQAFDQAMSRVGTSGVAHPYETRLTFQVWRTSGELLVRSAEAPLLSAPPATEG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCHHEEEECCCCCCCCCCCCCC
SHDLVENGHEWCGFLLADPQQGFLIWVGERDDVRQDLIQRIVSHTLWPTLIGVPLLVVAI
CHHHHHCCHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAIGWGLRPLQAMARVIRKRDAESLEPLAVTPLPKELEPMQYALNRLLTQIESVLERER
HHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHH
RFIADAAHELRTPLTILRIHAQNARQAETPEQRLEALDFLVHGVDRAARLASQLLTMARL
HHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPRLEVSQLQTFELNTLVREEMAELTPLALEKRVDLVFEEGEDCVIRSDPAAITIALQNL
CCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
LTNALNFAPTASEIRVALHTQEDGSAHLSVEDAGPGIDEQQKARLFERFYSQGHSNGAGL
HHHHHCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCH
GLAIVDMIVRKLESSLHLRNSAQGGLCAELRIKSRTS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]