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The map label for this gene is aer [H]

Identifier: 66046635

GI number: 66046635

Start: 4066069

End: 4067634

Strand: Direct

Name: aer [H]

Synonym: Psyr_3406

Alternate gene names: 66046635

Gene position: 4066069-4067634 (Clockwise)

Preceding gene: 66046634

Following gene: 66046636

Centisome position: 66.73

GC content: 61.75

Gene sequence:

>1566_bases
ATGCGCAACAACCAACCCATCACTCAACATGAGCGGACATTTCCTGCCGAACAACGACTGATTTCCACCACCGACACCCG
AGGCACCATCACCTATTGCAATGATGCCTTCGTCGACATCAGTGGTTACAGCGAGGCTGAATTGCTGGGTGCGGCGCACA
ACACCGTGCGTCATCCGGATGTACCGCCTGCGGTATTCGAGCACATGTGGACCACGCTCAAGTCCGGGCAGCCGTGGATG
GGCATCGTCAAGAACCGCTGCAAGAACGGCGATCATTATTGGGTCAATGCCTACGTGACGCCGGTGCTGGAAAACCGCCA
GGTAGTGGGTTTCGAGTCGGTACGCATCAAGCCGACCGCCGAACAGGTCCGCCGTGCCGAGGCGCTTTATACCCGGCTCA
ACAAGGGCAAGAGCGCGGTACCAGGCCGCGACAAGTGGCTGCCGGTACTTCAGGACTGGTTGCCGTTCATTCTGGTCAGC
CAGCTGAGCTTTCTGATCGGGGTGTGGCTCAATTCACATTGGGGGTTTGCCCTGGCTGCGGCATTGTCGGTACCGCTGGG
CCTGCTGGGGCTTTCCTGGCAGCAGCGTGGCACCAAACGCTTGTTGCGCCTGGCCGAACAGACCACGTCCGACCCGTTGA
TCGCGCAGATGTACACCGACAGCCGTGGGCCGCAAGCGCGCCTGGAAATGTCGATCCTCAGCCAGGAAGCGCGCATGAAA
ACCTGCCTGACGCGTTTGCAGGACACGGCCGAACACCTGAACAGTCAGGCCCGCCAGTCCAACTCGCTGGCCAATGCCAG
TTCGATCGGGCTGGAACGTCAGCGTGTGGAGACCGAGCAGGTTGCCGCCGCCATCAACCAGATGGCCGCCACCACTCAGG
AAGTCGCCAGCCACGTTAACCGTGCCGCTGATGCCACCCAGCAGGCCAACGAACTGACGCGTCGCGGGCGCGATATCGCC
GGTGAAACCCGCGAAGCCATTCAGCGCCTGTCCACCTCGGTGGGCGAAACCGGCCTGACCGTGACCCGCCTGGCCAAGGA
CAGCGATGAAATCGGTGGCGTGGTCGATGTGATCAAAGGCATTGCCGACCAGACCAACCTGCTGGCCCTCAACGCCGCGA
TCGAAGCGGCGCGCGCCGGTGAGATGGGTCGCGGCTTTGCCGTCGTGGCAGATGAAGTACGCCAGCTGGCACAACGCACC
GCCGAGTCCACCGGGCAGATTCATGGCCTGATCGCCAAACTGCAGCAGACCGCAACCGACGCGGTACACACCATGGACAC
CGGTCGCCGTCAGGCCGAAGAAGGCGTAGCCCGGGTACTGGAGGCAGATCAGGCGCTGGTGGGCATCAGCGAGGCTGTCG
CCAATATTACCGACATGACCACGCAAATCGCCACCGCCACGGAAGAGCAAAGCGCCGTGGCCGAGGAAATCAATCGCAAC
ATCGCCACCATCGCCAGCCTGGCAGACCAGACCTCTGACGAAGCGCGTCGCTCTGCCGTATTGAGTGGCGAACTGACCGA
CACGGCCAACTCACAGTATTCGCTGGTAGAGCGGTTTAATCGCTAA

Upstream 100 bases:

>100_bases
CAGGGCTGACTCCCCAGTCACTTGTCGCACGCCGCTCAATTTATCGACGTGCCCGCCGATAACCACGCCATAGTCTTCCG
GATCGAAGGATCGAAATCCC

Downstream 100 bases:

>100_bases
GGCCTGAAGCTGTTTACCAAACCTCGACGAACTTCGGTTGGTCGGGGCTTTTTTATGAGTGTTAACAGTGTGCCCTGTTA
GCGCTCTCTTCAAATCTGAC

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRNNQPITQHERTFPAEQRLISTTDTRGTITYCNDAFVDISGYSEAELLGAAHNTVRHPDVPPAVFEHMWTTLKSGQPWM
GIVKNRCKNGDHYWVNAYVTPVLENRQVVGFESVRIKPTAEQVRRAEALYTRLNKGKSAVPGRDKWLPVLQDWLPFILVS
QLSFLIGVWLNSHWGFALAAALSVPLGLLGLSWQQRGTKRLLRLAEQTTSDPLIAQMYTDSRGPQARLEMSILSQEARMK
TCLTRLQDTAEHLNSQARQSNSLANASSIGLERQRVETEQVAAAINQMAATTQEVASHVNRAADATQQANELTRRGRDIA
GETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
AESTGQIHGLIAKLQQTATDAVHTMDTGRRQAEEGVARVLEADQALVGISEAVANITDMTTQIATATEEQSAVAEEINRN
IATIASLADQTSDEARRSAVLSGELTDTANSQYSLVERFNR

Sequences:

>Translated_521_residues
MRNNQPITQHERTFPAEQRLISTTDTRGTITYCNDAFVDISGYSEAELLGAAHNTVRHPDVPPAVFEHMWTTLKSGQPWM
GIVKNRCKNGDHYWVNAYVTPVLENRQVVGFESVRIKPTAEQVRRAEALYTRLNKGKSAVPGRDKWLPVLQDWLPFILVS
QLSFLIGVWLNSHWGFALAAALSVPLGLLGLSWQQRGTKRLLRLAEQTTSDPLIAQMYTDSRGPQARLEMSILSQEARMK
TCLTRLQDTAEHLNSQARQSNSLANASSIGLERQRVETEQVAAAINQMAATTQEVASHVNRAADATQQANELTRRGRDIA
GETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
AESTGQIHGLIAKLQQTATDAVHTMDTGRRQAEEGVARVLEADQALVGISEAVANITDMTTQIATATEEQSAVAEEINRN
IATIASLADQTSDEARRSAVLSGELTDTANSQYSLVERFNR
>Mature_521_residues
MRNNQPITQHERTFPAEQRLISTTDTRGTITYCNDAFVDISGYSEAELLGAAHNTVRHPDVPPAVFEHMWTTLKSGQPWM
GIVKNRCKNGDHYWVNAYVTPVLENRQVVGFESVRIKPTAEQVRRAEALYTRLNKGKSAVPGRDKWLPVLQDWLPFILVS
QLSFLIGVWLNSHWGFALAAALSVPLGLLGLSWQQRGTKRLLRLAEQTTSDPLIAQMYTDSRGPQARLEMSILSQEARMK
TCLTRLQDTAEHLNSQARQSNSLANASSIGLERQRVETEQVAAAINQMAATTQEVASHVNRAADATQQANELTRRGRDIA
GETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
AESTGQIHGLIAKLQQTATDAVHTMDTGRRQAEEGVARVLEADQALVGISEAVANITDMTTQIATATEEQSAVAEEINRN
IATIASLADQTSDEARRSAVLSGELTDTANSQYSLVERFNR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=527, Percent_Identity=31.4990512333966, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=29.874213836478, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=34.7107438016529, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=194, Percent_Identity=39.1752577319588, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1787690, Length=226, Percent_Identity=34.9557522123894, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57016; Mature: 57016

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPITQHERTFPAEQRLISTTDTRGTITYCNDAFVDISGYSEAELLGAAHNTVRHPD
CCCCCCCCHHHHCCCHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCCCC
VPPAVFEHMWTTLKSGQPWMGIVKNRCKNGDHYWVNAYVTPVLENRQVVGFESVRIKPTA
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEEEHHCCCEEECCCCEEECCCH
EQVRRAEALYTRLNKGKSAVPGRDKWLPVLQDWLPFILVSQLSFLIGVWLNSHWGFALAA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALSVPLGLLGLSWQQRGTKRLLRLAEQTTSDPLIAQMYTDSRGPQARLEMSILSQEARMK
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TCLTRLQDTAEHLNSQARQSNSLANASSIGLERQRVETEQVAAAINQMAATTQEVASHVN
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAADATQQANELTRRGRDIAGETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVDVIKG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCHHHHHHHH
IADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRTAESTGQIHGLIAKLQQTATD
HCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVHTMDTGRRQAEEGVARVLEADQALVGISEAVANITDMTTQIATATEEQSAVAEEINRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATIASLADQTSDEARRSAVLSGELTDTANSQYSLVERFNR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRNNQPITQHERTFPAEQRLISTTDTRGTITYCNDAFVDISGYSEAELLGAAHNTVRHPD
CCCCCCCCHHHHCCCHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCCCC
VPPAVFEHMWTTLKSGQPWMGIVKNRCKNGDHYWVNAYVTPVLENRQVVGFESVRIKPTA
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEEEHHCCCEEECCCCEEECCCH
EQVRRAEALYTRLNKGKSAVPGRDKWLPVLQDWLPFILVSQLSFLIGVWLNSHWGFALAA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALSVPLGLLGLSWQQRGTKRLLRLAEQTTSDPLIAQMYTDSRGPQARLEMSILSQEARMK
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TCLTRLQDTAEHLNSQARQSNSLANASSIGLERQRVETEQVAAAINQMAATTQEVASHVN
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAADATQQANELTRRGRDIAGETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVDVIKG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCHHHHHHHH
IADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRTAESTGQIHGLIAKLQQTATD
HCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVHTMDTGRRQAEEGVARVLEADQALVGISEAVANITDMTTQIATATEEQSAVAEEINRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATIASLADQTSDEARRSAVLSGELTDTANSQYSLVERFNR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]