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The map label for this gene is ttdR [H]

Identifier: 66046626

GI number: 66046626

Start: 4054281

End: 4055165

Strand: Reverse

Name: ttdR [H]

Synonym: Psyr_3397

Alternate gene names: 66046626

Gene position: 4055165-4054281 (Counterclockwise)

Preceding gene: 66046632

Following gene: 66046625

Centisome position: 66.55

GC content: 64.41

Gene sequence:

>885_bases
ATGATCGCCATCGAAGACCTGCGTCTGGCCGTGACCCTGTCGCGCTGCGAATCGCTCAGTGCTGCCGCCAGAATCCTCAA
TGTTTCGCCGCCCGCATTGTCGATGCGCTTGCGCAAACTGGAGACGCAACTGGGCATCACCCTGGCCAGTCGCGACGCCA
GACGCCTGAGTCTGACCGCTGATGGCGAGCGTTTCGCCCGCGAAAGCGCACAGTTGCTGGAGCAACTGGAGGCACTCCCG
GAGTCCTTCAGGCAGCGAGATGAACGACTGGTGGGCACGCTGCGCCTGGCAGCGCCGTTCGGTTATGGACGCCAGCGCAT
TGCGCCGCTGCTGGCGCGCTTCGCCAGGCTGCACCCGCAGTTGTGCCTGCAACTGGACCTGCGCGAAACACCCTGGCCGG
ACCGTCATGACAGCGATGCGGTGATACACATCGGCAGCCTCAATGACAGCCAGTGGATCGCCATGCCGTTGGCACAGAAT
CATCGCTGGTTGTGCGCCAGCCCGGCGTATATCGAGCAGCATGGTGTGCCCTCGACGCCCGAGCAGCTGGCCGGCCATCG
CTGCATCTGCATTCGCGAAAACGATGAAGACGTCACCCTCTGGCACCTGAGCAAGGGCCAGACGAAAAAGACCCTGCGCA
TCGAGCCCGCGCTGCTCAGTAACGACGGCTCGGTCGCCCGGCGCTGGGCCGAGCAGGGGCTGGGCATCGTGTTGCGCTCG
CAGTGGGACGTCAGCGACGCCATTGCCAGTGGCAGGCTGGTGCGGGTGCTTGCCGATTGGCAGCTGGCCAGTGCGCCGAT
CAACCTGCTGGTGCCTGTACGCAAGCATCGCAGCGCACGGGTACAGGCGTTGACCGAGTTTCTCGAGACAGCCCTGAAAG
CCTGA

Upstream 100 bases:

>100_bases
ACATGGAAAGCGCTCGTGTGACTAGGTACGGCAGCCACTCTACGCAGCGATGATGAAGCTGTGGTTCAATGCGTGATCAT
CAATCCTTAAGCTAAAGTGA

Downstream 100 bases:

>100_bases
TTCGGCACAGTACCGGCACGCTGTTGGTCGCTGGGTTGAACACCTTAATTGACGCTCACGGCAACGCGCGGGTATAAACC
GCGTCTTGTGTTTTTGTCGG

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MIAIEDLRLAVTLSRCESLSAAARILNVSPPALSMRLRKLETQLGITLASRDARRLSLTADGERFARESAQLLEQLEALP
ESFRQRDERLVGTLRLAAPFGYGRQRIAPLLARFARLHPQLCLQLDLRETPWPDRHDSDAVIHIGSLNDSQWIAMPLAQN
HRWLCASPAYIEQHGVPSTPEQLAGHRCICIRENDEDVTLWHLSKGQTKKTLRIEPALLSNDGSVARRWAEQGLGIVLRS
QWDVSDAIASGRLVRVLADWQLASAPINLLVPVRKHRSARVQALTEFLETALKA

Sequences:

>Translated_294_residues
MIAIEDLRLAVTLSRCESLSAAARILNVSPPALSMRLRKLETQLGITLASRDARRLSLTADGERFARESAQLLEQLEALP
ESFRQRDERLVGTLRLAAPFGYGRQRIAPLLARFARLHPQLCLQLDLRETPWPDRHDSDAVIHIGSLNDSQWIAMPLAQN
HRWLCASPAYIEQHGVPSTPEQLAGHRCICIRENDEDVTLWHLSKGQTKKTLRIEPALLSNDGSVARRWAEQGLGIVLRS
QWDVSDAIASGRLVRVLADWQLASAPINLLVPVRKHRSARVQALTEFLETALKA
>Mature_294_residues
MIAIEDLRLAVTLSRCESLSAAARILNVSPPALSMRLRKLETQLGITLASRDARRLSLTADGERFARESAQLLEQLEALP
ESFRQRDERLVGTLRLAAPFGYGRQRIAPLLARFARLHPQLCLQLDLRETPWPDRHDSDAVIHIGSLNDSQWIAMPLAQN
HRWLCASPAYIEQHGVPSTPEQLAGHRCICIRENDEDVTLWHLSKGQTKKTLRIEPALLSNDGSVARRWAEQGLGIVLRS
QWDVSDAIASGRLVRVLADWQLASAPINLLVPVRKHRSARVQALTEFLETALKA

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=33.1010452961672, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=34.7222222222222, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=30.3754266211604, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=28.135593220339, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789639, Length=281, Percent_Identity=26.6903914590747, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=23.5880398671096, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=25.6317689530686, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=120, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788706, Length=252, Percent_Identity=25.3968253968254, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI157672245, Length=187, Percent_Identity=29.4117647058824, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32935; Mature: 32935

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIEDLRLAVTLSRCESLSAAARILNVSPPALSMRLRKLETQLGITLASRDARRLSLTA
CEEEHHHHHEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCEEEEEEC
DGERFARESAQLLEQLEALPESFRQRDERLVGTLRLAAPFGYGRQRIAPLLARFARLHPQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCHH
LCLQLDLRETPWPDRHDSDAVIHIGSLNDSQWIAMPLAQNHRWLCASPAYIEQHGVPSTP
HEEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHCCCCCCH
EQLAGHRCICIRENDEDVTLWHLSKGQTKKTLRIEPALLSNDGSVARRWAEQGLGIVLRS
HHHCCCEEEEEECCCCCEEEEEECCCCCCCEEEECCCEECCCHHHHHHHHHCCCCEEEEC
QWDVSDAIASGRLVRVLADWQLASAPINLLVPVRKHRSARVQALTEFLETALKA
CCCHHHHHHCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAIEDLRLAVTLSRCESLSAAARILNVSPPALSMRLRKLETQLGITLASRDARRLSLTA
CEEEHHHHHEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCEEEEEEC
DGERFARESAQLLEQLEALPESFRQRDERLVGTLRLAAPFGYGRQRIAPLLARFARLHPQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCHH
LCLQLDLRETPWPDRHDSDAVIHIGSLNDSQWIAMPLAQNHRWLCASPAYIEQHGVPSTP
HEEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHCCCCCCH
EQLAGHRCICIRENDEDVTLWHLSKGQTKKTLRIEPALLSNDGSVARRWAEQGLGIVLRS
HHHCCCEEEEEECCCCCEEEEEECCCCCCCEEEECCCEECCCHHHHHHHHHCCCCEEEEC
QWDVSDAIASGRLVRVLADWQLASAPINLLVPVRKHRSARVQALTEFLETALKA
CCCHHHHHHCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]