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The map label for this gene is hlyB [H]

Identifier: 66046580

GI number: 66046580

Start: 4007226

End: 4008938

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_3351

Alternate gene names: 66046580

Gene position: 4008938-4007226 (Counterclockwise)

Preceding gene: 66046581

Following gene: 66046579

Centisome position: 65.79

GC content: 59.6

Gene sequence:

>1713_bases
ATGACATCATCGCTGTTTGATCAACTCATTCCGGCACTGACACCACTCCTCATTCAGCAACAGGTAAGCCCCATGAACGT
CCTGCGTCAGTCCAAGTTTTCCACCAAGCTGCTCTCTGCTTTCATCATTTGTGCATTGATTACGCTGGCCGTCGGCGCTC
TGGGAATGGTGGGCGTGACCCGCCTGGCCAACGCCCTTGAGCTGACCTTCTCCAACAACCTTGTATCGGTCAGCAACACC
AATGAAGCGCTGACCAGCTTCACCGCTCACAACCGCGGGTTGTACCGTTTGCTGGATGCGCAGGATGGCGGTGTCTCCGA
AACGGACAAGGATCGAGTTCGTCAGGCGTTGAGTGATGACCTGGCCCGTGCGCAAAAAGTGTTCGCGATCTACCGCGCCA
CGCCTCTGGAAGATGACGAGCGCGCCGCCGGTGACCAGCTGGAACTGATGCTGCCCGCTTACATTTCCGGCTCTCAACAG
GTTGTCGACCTGATGAAGGCGGGTAATTACGAGGCTGCCCGGACCCAGTTGAACAGCCTGTCCTCGGAAAGCTTTACCAA
GGTGCGCAGTTACATGCGCGTCATGATCGACTCCAACAATCGTCAGATCAAGGAAGGCGCAGCCGCTGCTGCCGACCTGA
AGGCCAGTTCGGTATTGATGCTGGAGATTGGCGTGGTGATCGCGTTTCTGGTGGCGATCATGCTGGGCGTGCTGATTACC
CGCATGATCACCCGTCCTTTGGCTGTTGCAGTCGCCAGTGCTCAGCGCATTGCGGGCGGTGACCTGACTCAGCCTATTGT
TTCTACCAGTGGCGATGAGGCCGGACAACTGTTGAACGCGCTGTCCGATATGCAGGGCGGTCTGAAAAACACCATTCAAC
AGATTGCCAGTGCCTCGGACCAGCTGGCTTCCGCTGCCGAAGAGCTGAGCGCCGTCACCGATGAAAGCACCCGCGGGCTG
ACTCGCCAGAACGACGAAATCCAGCAGGCGGCAACAGCCGTCAATCAGATGACTGCCGCGGTGGAAGAAGTGGCGCGCAA
TGCGGTGTCCACGTCTGAAGCGTCGAAGTCCGCTACAGACGATGCGGTTGATGGCCGTGGTCAGGTCGATCACACGGTCA
AGGGCATCACCACCATGGTCCACGAGATCACCGCATCCACTGGCGCTGTCTCCGAGCTGGCCGGGCATGTGCGGGAAATC
AGCAAGGTGCTTGACGTGATTCGCAGTATCGCCGAGCAGACCAACCTGCTGGCCTTGAACGCCGCCATTGAAGCTGCACG
TGCTGGCGAGCAGGGCCGTGGTTTTGCGGTGGTGGCTGACGAGGTTCGGGCCCTGGCGCACCGTACCCAGGCATCGACAG
TGGAAATCGAAGGCATGATCAGCACCGTGCAGTCAGGTGCCGACGGCGCGGTTGCGGCGATGGGCAAGAGCCTGTCGCTG
GCCACCAACACGCAGGAACTGGCCCTGCGTGCGGGCGCGGCGCTGGAGAAAATCACCCTGGGTGTAGCCACCATCAACGA
GCGCAATCTGGTCATTGCCTCCGCTTCGGAAGAGCAGGCCCAGGTAGCTCGCGAGGTGGACCGCAACCTGATCAATATTC
AGGACCTGTCGACCCAGAGCGCTGCCGGTGCCAACCAGACCAGCGCGTCCAGTCAGGAACTGTCGCGACTGGCCACCTCG
TTCAACTCACTGGTTGCCAACTTCAAGCTGTAA

Upstream 100 bases:

>100_bases
GACCGATAGAGGGCATTAGTTGCACACGTGCGACTTGTCAAAGCCCTTTTTATCAAAAAGCGAGGAGGCCGTGGAACGAT
CCAAATGAGGTGAAGTCATT

Downstream 100 bases:

>100_bases
GTCGTTCTCACGAGGCATTGTCTGGCGCACGTCTGGGCTCGATCGGTTGTTAAATTCCGGTCAGGCATAAAAAAGGCGTT
GCGCCCGACCGGGTCATTTC

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MTSSLFDQLIPALTPLLIQQQVSPMNVLRQSKFSTKLLSAFIICALITLAVGALGMVGVTRLANALELTFSNNLVSVSNT
NEALTSFTAHNRGLYRLLDAQDGGVSETDKDRVRQALSDDLARAQKVFAIYRATPLEDDERAAGDQLELMLPAYISGSQQ
VVDLMKAGNYEAARTQLNSLSSESFTKVRSYMRVMIDSNNRQIKEGAAAAADLKASSVLMLEIGVVIAFLVAIMLGVLIT
RMITRPLAVAVASAQRIAGGDLTQPIVSTSGDEAGQLLNALSDMQGGLKNTIQQIASASDQLASAAEELSAVTDESTRGL
TRQNDEIQQAATAVNQMTAAVEEVARNAVSTSEASKSATDDAVDGRGQVDHTVKGITTMVHEITASTGAVSELAGHVREI
SKVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAHRTQASTVEIEGMISTVQSGADGAVAAMGKSLSL
ATNTQELALRAGAALEKITLGVATINERNLVIASASEEQAQVAREVDRNLINIQDLSTQSAAGANQTSASSQELSRLATS
FNSLVANFKL

Sequences:

>Translated_570_residues
MTSSLFDQLIPALTPLLIQQQVSPMNVLRQSKFSTKLLSAFIICALITLAVGALGMVGVTRLANALELTFSNNLVSVSNT
NEALTSFTAHNRGLYRLLDAQDGGVSETDKDRVRQALSDDLARAQKVFAIYRATPLEDDERAAGDQLELMLPAYISGSQQ
VVDLMKAGNYEAARTQLNSLSSESFTKVRSYMRVMIDSNNRQIKEGAAAAADLKASSVLMLEIGVVIAFLVAIMLGVLIT
RMITRPLAVAVASAQRIAGGDLTQPIVSTSGDEAGQLLNALSDMQGGLKNTIQQIASASDQLASAAEELSAVTDESTRGL
TRQNDEIQQAATAVNQMTAAVEEVARNAVSTSEASKSATDDAVDGRGQVDHTVKGITTMVHEITASTGAVSELAGHVREI
SKVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAHRTQASTVEIEGMISTVQSGADGAVAAMGKSLSL
ATNTQELALRAGAALEKITLGVATINERNLVIASASEEQAQVAREVDRNLINIQDLSTQSAAGANQTSASSQELSRLATS
FNSLVANFKL
>Mature_569_residues
TSSLFDQLIPALTPLLIQQQVSPMNVLRQSKFSTKLLSAFIICALITLAVGALGMVGVTRLANALELTFSNNLVSVSNTN
EALTSFTAHNRGLYRLLDAQDGGVSETDKDRVRQALSDDLARAQKVFAIYRATPLEDDERAAGDQLELMLPAYISGSQQV
VDLMKAGNYEAARTQLNSLSSESFTKVRSYMRVMIDSNNRQIKEGAAAAADLKASSVLMLEIGVVIAFLVAIMLGVLITR
MITRPLAVAVASAQRIAGGDLTQPIVSTSGDEAGQLLNALSDMQGGLKNTIQQIASASDQLASAAEELSAVTDESTRGLT
RQNDEIQQAATAVNQMTAAVEEVARNAVSTSEASKSATDDAVDGRGQVDHTVKGITTMVHEITASTGAVSELAGHVREIS
KVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAHRTQASTVEIEGMISTVQSGADGAVAAMGKSLSLA
TNTQELALRAGAALEKITLGVATINERNLVIASASEEQAQVAREVDRNLINIQDLSTQSAAGANQTSASSQELSRLATSF
NSLVANFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=476, Percent_Identity=31.3025210084034, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1788194, Length=489, Percent_Identity=29.4478527607362, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI2367378, Length=510, Percent_Identity=29.0196078431373, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=37.4581939799331, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=30.6990881458967, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60015; Mature: 59883

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSLFDQLIPALTPLLIQQQVSPMNVLRQSKFSTKLLSAFIICALITLAVGALGMVGVT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLANALELTFSNNLVSVSNTNEALTSFTAHNRGLYRLLDAQDGGVSETDKDRVRQALSDD
HHHHHHHEEECCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LARAQKVFAIYRATPLEDDERAAGDQLELMLPAYISGSQQVVDLMKAGNYEAARTQLNSL
HHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHC
SSESFTKVRSYMRVMIDSNNRQIKEGAAAAADLKASSVLMLEIGVVIAFLVAIMLGVLIT
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RMITRPLAVAVASAQRIAGGDLTQPIVSTSGDEAGQLLNALSDMQGGLKNTIQQIASASD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLASAAEELSAVTDESTRGLTRQNDEIQQAATAVNQMTAAVEEVARNAVSTSEASKSATD
HHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAVDGRGQVDHTVKGITTMVHEITASTGAVSELAGHVREISKVLDVIRSIAEQTNLLALN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHH
AAIEAARAGEQGRGFAVVADEVRALAHRTQASTVEIEGMISTVQSGADGAVAAMGKSLSL
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHCCCCEE
ATNTQELALRAGAALEKITLGVATINERNLVIASASEEQAQVAREVDRNLINIQDLSTQS
ECCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHCCCHH
AAGANQTSASSQELSRLATSFNSLVANFKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSSLFDQLIPALTPLLIQQQVSPMNVLRQSKFSTKLLSAFIICALITLAVGALGMVGVT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLANALELTFSNNLVSVSNTNEALTSFTAHNRGLYRLLDAQDGGVSETDKDRVRQALSDD
HHHHHHHEEECCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LARAQKVFAIYRATPLEDDERAAGDQLELMLPAYISGSQQVVDLMKAGNYEAARTQLNSL
HHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHC
SSESFTKVRSYMRVMIDSNNRQIKEGAAAAADLKASSVLMLEIGVVIAFLVAIMLGVLIT
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RMITRPLAVAVASAQRIAGGDLTQPIVSTSGDEAGQLLNALSDMQGGLKNTIQQIASASD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLASAAEELSAVTDESTRGLTRQNDEIQQAATAVNQMTAAVEEVARNAVSTSEASKSATD
HHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAVDGRGQVDHTVKGITTMVHEITASTGAVSELAGHVREISKVLDVIRSIAEQTNLLALN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHH
AAIEAARAGEQGRGFAVVADEVRALAHRTQASTVEIEGMISTVQSGADGAVAAMGKSLSL
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHCCCCEE
ATNTQELALRAGAALEKITLGVATINERNLVIASASEEQAQVAREVDRNLINIQDLSTQS
ECCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHCCCHH
AAGANQTSASSQELSRLATSFNSLVANFKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]