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The map label for this gene is degU [H]

Identifier: 66046528

GI number: 66046528

Start: 3947701

End: 3948363

Strand: Direct

Name: degU [H]

Synonym: Psyr_3299

Alternate gene names: 66046528

Gene position: 3947701-3948363 (Clockwise)

Preceding gene: 66046527

Following gene: 66046530

Centisome position: 64.78

GC content: 60.63

Gene sequence:

>663_bases
ATGACCTGCAATCTGTTACTGGTCGACGACCACTCCCTTATCAGAGCCGGCGTGCGAGCGCTGGTTGCAGACATGCCTGG
ATACACCATCCTGGGCGAAACGGCTGACGGCGCGCAGCTGGCGGGTCTTGCGCAGCAGCTCAAGCCCGACATCATCCTGT
TCGACATCTGCATGAAAAGTGTCGACGGCCTGGATGCACTCGAGCAGCTGTTGAAGGTGCAACCGCACTGCAAGGTGTTG
ATCCTGTCGATGCAGAACGATCCGGACATGATCATGCGTGCGCTCGACATTGGCGCGCAGGGCTACCTGCTCAAGGACAC
TACGGCTGCGGAACTCGAACAGGCACTGGGGGCGCTGCGTGGCAACGAGCGCTACCTGAGCCCGGGCATTGCCCACACCG
TCATCGAGCGCGCCCTGCGTGGCAAGCGATCCGACAGGGCCCGGTCGGCAAAGGAACGGTATCACCTGACCGCTCGGCAA
CTTGAAATCCTGCGCCTGATAGTGCGCGGCAAGTCCACACGCGAGATCGCCGATGGCCTGGGACTGAGCGTCAAGACCAT
CGAGACTCACCGTGCCCAGGTCATGAAGCGCTTGCAGATATTCGACGTGGCCGGGTTGGTGCTGTTTTGCGTTCGCGAAC
GGATTATCAGTCTGGACGATTGA

Upstream 100 bases:

>100_bases
CATTTTCCGTTCATTGTCTTCACTGCCGCTAACATCGTCTTCAAGCATGACCGGAGACTGCACACGCGCTTGAGCGGCCC
CATTTGCACAAGAAATCACA

Downstream 100 bases:

>100_bases
GCTTCGGGGCGCCGCCCAGTAACGGCGAGTCCGCTGGCAGGTGCACGTGAAGCGCGCCTGGCCGGGCCTCGAAACGCAGG
TCCTCGCCCGACAGCGGCTC

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTCNLLLVDDHSLIRAGVRALVADMPGYTILGETADGAQLAGLAQQLKPDIILFDICMKSVDGLDALEQLLKVQPHCKVL
ILSMQNDPDMIMRALDIGAQGYLLKDTTAAELEQALGALRGNERYLSPGIAHTVIERALRGKRSDRARSAKERYHLTARQ
LEILRLIVRGKSTREIADGLGLSVKTIETHRAQVMKRLQIFDVAGLVLFCVRERIISLDD

Sequences:

>Translated_220_residues
MTCNLLLVDDHSLIRAGVRALVADMPGYTILGETADGAQLAGLAQQLKPDIILFDICMKSVDGLDALEQLLKVQPHCKVL
ILSMQNDPDMIMRALDIGAQGYLLKDTTAAELEQALGALRGNERYLSPGIAHTVIERALRGKRSDRARSAKERYHLTARQ
LEILRLIVRGKSTREIADGLGLSVKTIETHRAQVMKRLQIFDVAGLVLFCVRERIISLDD
>Mature_219_residues
TCNLLLVDDHSLIRAGVRALVADMPGYTILGETADGAQLAGLAQQLKPDIILFDICMKSVDGLDALEQLLKVQPHCKVLI
LSMQNDPDMIMRALDIGAQGYLLKDTTAAELEQALGALRGNERYLSPGIAHTVIERALRGKRSDRARSAKERYHLTARQL
EILRLIVRGKSTREIADGLGLSVKTIETHRAQVMKRLQIFDVAGLVLFCVRERIISLDD

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=26.7942583732057, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=32.5242718446602, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787473, Length=188, Percent_Identity=34.0425531914894, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=26.2376237623762, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788712, Length=212, Percent_Identity=26.8867924528302, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=31.4720812182741, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24324; Mature: 24193

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCNLLLVDDHSLIRAGVRALVADMPGYTILGETADGAQLAGLAQQLKPDIILFDICMKS
CCEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
VDGLDALEQLLKVQPHCKVLILSMQNDPDMIMRALDIGAQGYLLKDTTAAELEQALGALR
CCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHC
GNERYLSPGIAHTVIERALRGKRSDRARSAKERYHLTARQLEILRLIVRGKSTREIADGL
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
GLSVKTIETHRAQVMKRLQIFDVAGLVLFCVRERIISLDD
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TCNLLLVDDHSLIRAGVRALVADMPGYTILGETADGAQLAGLAQQLKPDIILFDICMKS
CEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
VDGLDALEQLLKVQPHCKVLILSMQNDPDMIMRALDIGAQGYLLKDTTAAELEQALGALR
CCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHC
GNERYLSPGIAHTVIERALRGKRSDRARSAKERYHLTARQLEILRLIVRGKSTREIADGL
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
GLSVKTIETHRAQVMKRLQIFDVAGLVLFCVRERIISLDD
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]