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The map label for this gene is nahR [H]

Identifier: 66046331

GI number: 66046331

Start: 3719982

End: 3720911

Strand: Direct

Name: nahR [H]

Synonym: Psyr_3102

Alternate gene names: 66046331

Gene position: 3719982-3720911 (Clockwise)

Preceding gene: 66046329

Following gene: 66046336

Centisome position: 61.05

GC content: 62.9

Gene sequence:

>930_bases
ATGAATCGAAATGAACTGCGCAAGGCCGACATCAACCTGATGGTGGTATTCGAAACATTGATGCAGGAGCGTAACGTCAC
CCGCGCAGCCGAAAAACTTTTTCTCGGCCAACCCACGATAAGCGCCGCCCTGAATCGCCTGCGCAGTCTGCTCAACGACC
CGCTGTTCATCCGCGTCGGCCATCGTATGGAACCCACCGCACGCGCTCACGAGATTCTCAAGCACCTGACGCCCGCGCTG
GACGCCATGTCCACGGCGCTCAGCCTGACCACCGACTTCGATCCGTCAGTCAGCAAAATGACCTTTCGCATCGGCCTGAC
CGATGACGTCGAGTTCGGCCTGCTGCCGGCGATGCTCAAGGCCATCCGCGAAGAGGCGCCCGGCGTGGTGATCGTGGTCA
AGCATGTCGACTACCTGAATATCTCCGAGGTGCTGATGTCCGGCGACATCACCGTCGGCGTCTGCCTGACCCGTGAACTG
CCGGCCAACGCCAAGCGCAAGACCCTGCGTAACGTACAGCCAAGGCTGGTGCGCGCCGACAAGCCTGCCGGTCCCATGAG
CCTGGACGAATACTGCTCGCGCCCACACGTTGTGGTCTCGCACGTCGCGAGTGTCAGCAGTTTCGCCGATGAGTGGCTGA
CCGCGCTGGGACGCAAGCGTCAGGTGGTGTTGTCGGTGCCGCAGTTCGCCACCCTGCCCGCTTTGATGGCCGGCACCGAC
ATGATTTCGGGGCTGTCCGACTACGCGGCAAAGGCCATGAGCGCACTGGGTCTGCTGTATGACGAGCCACTGCCCTTCCC
CACGCCGGGGCTGGACCTGTCGATGACGTGGCTGAGTGTGATGGACAGCGACCCTGCCGAGCGTTGGCTGCGCAGCAGGA
TCGAGGCGTTCATGGGCGAGCGCCAGGAAGCGCCCGCCCTGGCCGAATGA

Upstream 100 bases:

>100_bases
ACGATGGCAAAATGCTGGACGCCTCCTGCCGTGCCTGCCTAGACTGGGCCGTCCGTTACAGGCCGTCGTGGCCATCCGGG
TCTGACGCCAAGGAACAGCA

Downstream 100 bases:

>100_bases
TCAGCCGAAACGACCGGTGATGTAATCTTCGGTCTGGGTCTTGGAGGGCTTGGTGAAGATGGTGTCGGTGTCGCCGTGCT
CGATCAGTTCACCCATGAAC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNRNELRKADINLMVVFETLMQERNVTRAAEKLFLGQPTISAALNRLRSLLNDPLFIRVGHRMEPTARAHEILKHLTPAL
DAMSTALSLTTDFDPSVSKMTFRIGLTDDVEFGLLPAMLKAIREEAPGVVIVVKHVDYLNISEVLMSGDITVGVCLTREL
PANAKRKTLRNVQPRLVRADKPAGPMSLDEYCSRPHVVVSHVASVSSFADEWLTALGRKRQVVLSVPQFATLPALMAGTD
MISGLSDYAAKAMSALGLLYDEPLPFPTPGLDLSMTWLSVMDSDPAERWLRSRIEAFMGERQEAPALAE

Sequences:

>Translated_309_residues
MNRNELRKADINLMVVFETLMQERNVTRAAEKLFLGQPTISAALNRLRSLLNDPLFIRVGHRMEPTARAHEILKHLTPAL
DAMSTALSLTTDFDPSVSKMTFRIGLTDDVEFGLLPAMLKAIREEAPGVVIVVKHVDYLNISEVLMSGDITVGVCLTREL
PANAKRKTLRNVQPRLVRADKPAGPMSLDEYCSRPHVVVSHVASVSSFADEWLTALGRKRQVVLSVPQFATLPALMAGTD
MISGLSDYAAKAMSALGLLYDEPLPFPTPGLDLSMTWLSVMDSDPAERWLRSRIEAFMGERQEAPALAE
>Mature_309_residues
MNRNELRKADINLMVVFETLMQERNVTRAAEKLFLGQPTISAALNRLRSLLNDPLFIRVGHRMEPTARAHEILKHLTPAL
DAMSTALSLTTDFDPSVSKMTFRIGLTDDVEFGLLPAMLKAIREEAPGVVIVVKHVDYLNISEVLMSGDITVGVCLTREL
PANAKRKTLRNVQPRLVRADKPAGPMSLDEYCSRPHVVVSHVASVSSFADEWLTALGRKRQVVLSVPQFATLPALMAGTD
MISGLSDYAAKAMSALGLLYDEPLPFPTPGLDLSMTWLSVMDSDPAERWLRSRIEAFMGERQEAPALAE

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=22.2222222222222, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786820, Length=90, Percent_Identity=35.5555555555556, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081766, Length=126, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790147, Length=296, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34135; Mature: 34135

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNELRKADINLMVVFETLMQERNVTRAAEKLFLGQPTISAALNRLRSLLNDPLFIRVG
CCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEC
HRMEPTARAHEILKHLTPALDAMSTALSLTTDFDPSVSKMTFRIGLTDDVEFGLLPAMLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
AIREEAPGVVIVVKHVDYLNISEVLMSGDITVGVCLTRELPANAKRKTLRNVQPRLVRAD
HHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCHHEECC
KPAGPMSLDEYCSRPHVVVSHVASVSSFADEWLTALGRKRQVVLSVPQFATLPALMAGTD
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
MISGLSDYAAKAMSALGLLYDEPLPFPTPGLDLSMTWLSVMDSDPAERWLRSRIEAFMGE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RQEAPALAE
CCCCCCCCC
>Mature Secondary Structure
MNRNELRKADINLMVVFETLMQERNVTRAAEKLFLGQPTISAALNRLRSLLNDPLFIRVG
CCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEC
HRMEPTARAHEILKHLTPALDAMSTALSLTTDFDPSVSKMTFRIGLTDDVEFGLLPAMLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
AIREEAPGVVIVVKHVDYLNISEVLMSGDITVGVCLTRELPANAKRKTLRNVQPRLVRAD
HHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCHHEECC
KPAGPMSLDEYCSRPHVVVSHVASVSSFADEWLTALGRKRQVVLSVPQFATLPALMAGTD
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
MISGLSDYAAKAMSALGLLYDEPLPFPTPGLDLSMTWLSVMDSDPAERWLRSRIEAFMGE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RQEAPALAE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]