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The map label for this gene is lktD [H]

Identifier: 66046306

GI number: 66046306

Start: 3676622

End: 3678043

Strand: Reverse

Name: lktD [H]

Synonym: Psyr_3075

Alternate gene names: 66046306

Gene position: 3678043-3676622 (Counterclockwise)

Preceding gene: 66046307

Following gene: 66046305

Centisome position: 60.36

GC content: 59.0

Gene sequence:

>1422_bases
ATGTCTAACGCCGAATCGACCGGACTACTGCAGCGCTACCGCCGCGTGTGGCGCCAATCTTGGCGTCACCGTCGTGAGAT
GGATGCCCCCAAGCGCTTGGCGCATGAAGTTCAGTTTCTGCCCGCTGCGCTGGAACTCCAGGATAAACCCAGTCATCCCG
CGCCGCGTGTTTTCATGTGGGCGATCATGTTTTTTGCCGCTCTGGCGTTGCTATGGGCATGCCTGGGCAAGATTGACGTG
GTAGCGACAGCCAGCGGCAAAATCATTCCCAGCGGCAAGACGAAAACCATTCAGTCCAGTGAAACCGCTGTGGTCAAGGC
GATTCATGTGCGTGACGGGCAATCGGTCAAGGCCGGTCAGTTGCTTTTGGAGCTGGACTCCACATCTGCGGATGCTGATG
TCGGACGCGTCCGCAGTGATTTGCTGGCTGCGCGAATCGACAGCGCTCGCGCGGCTGCCATGCTCGACGCAATCAATCAG
CGCAAGCCACCTCGGGATCTGACCGGCACCATACTGGATGCCGACCCGATGCATGTATTGGCGGCTGAGCGCTGGCTGCA
GGGCCAGTATCAAGAGTACCGCAGTAGCCTTGACCTGGTAGACGCCGAAATTCAGCAACGCCAGGCCGACATTCAGGCCG
CGCGTATTCAAGTCATGAGTTTGCAGAAAACTTTGCCTATCGCCACCAAGCTGGCAAGTGACTACGAAAACCTCCTGAAA
AAGCAGTACATCGCCCGTCACGCTTACCTGGAAAAGGAACAAGCGCGCCTGGACCTCGAACGCCAACTGAGCGTGCAGCA
AGCCAGCGTCCTGCAGTCCACCGCCGCCCGCCAGGAAGCAGAGCGCCGCCGCGAAGGCGTGGTCGCCCAGACCCGCCGCG
CCATGCTTGACCTGTTGCAGCAAGCCGATCAAAAGATCGCATCTTTCAATCAGGACCTGACCAAGGCTCGCTATCAGGAA
GACCTCACCACCCTCGAAGCGCCGGTAGACGGCACCGTCCAGCAACTGGCCGTGCACACCGTCGGCGGCGTAGTCACCCC
CGCACAACCGCTGATGGTATTAGTCCCCGACGGCCAGCCCGTGGAAGTGGAAGCCATGCTGGAAAACAAGGACGTCGGCT
TTGTTCGCGCCGGGCAGGCCGTTACCGTCAAGGTCGAAACGTTCACCTTCACCAAGTACGGCACGATAGAAGGCGAAGTC
ATCAGCGTCTCCAACGACGCCATCGAAGATGAAAAGCGCGGCTTGATCTACAGCAGCAAGATTCGTCTTAACAGCGATAC
GCTGAATGTGAATGGCGTGGACATCAAGTTGTCGCCGGGCATGGCGGTGACGGCGGAAGTGACGACGAACAAGCGGCGGG
TGATTGAGTATTTCCTGAGTCCGTTGCAGCAGCATGCGTCGGAGAGTTTCAGGGAGCGGTAG

Upstream 100 bases:

>100_bases
GATCGCGGGCAAATTGTAGAGCAGGGCACTCATGCCGAATTGCTCACACATCAAGCAGGTCATTACTCGCGCCTTCATCG
CCTGCAGCAGGGAGGCAGCC

Downstream 100 bases:

>100_bases
TAAGTGGAAATCTGGATTAATAACAGTAACTCAATCGGTACTGACTCATGGGCGATACAATGGCAACTATTATCAACGGG
CAGAGTGGCGATGATTGGCT

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSNAESTGLLQRYRRVWRQSWRHRREMDAPKRLAHEVQFLPAALELQDKPSHPAPRVFMWAIMFFAALALLWACLGKIDV
VATASGKIIPSGKTKTIQSSETAVVKAIHVRDGQSVKAGQLLLELDSTSADADVGRVRSDLLAARIDSARAAAMLDAINQ
RKPPRDLTGTILDADPMHVLAAERWLQGQYQEYRSSLDLVDAEIQQRQADIQAARIQVMSLQKTLPIATKLASDYENLLK
KQYIARHAYLEKEQARLDLERQLSVQQASVLQSTAARQEAERRREGVVAQTRRAMLDLLQQADQKIASFNQDLTKARYQE
DLTTLEAPVDGTVQQLAVHTVGGVVTPAQPLMVLVPDGQPVEVEAMLENKDVGFVRAGQAVTVKVETFTFTKYGTIEGEV
ISVSNDAIEDEKRGLIYSSKIRLNSDTLNVNGVDIKLSPGMAVTAEVTTNKRRVIEYFLSPLQQHASESFRER

Sequences:

>Translated_473_residues
MSNAESTGLLQRYRRVWRQSWRHRREMDAPKRLAHEVQFLPAALELQDKPSHPAPRVFMWAIMFFAALALLWACLGKIDV
VATASGKIIPSGKTKTIQSSETAVVKAIHVRDGQSVKAGQLLLELDSTSADADVGRVRSDLLAARIDSARAAAMLDAINQ
RKPPRDLTGTILDADPMHVLAAERWLQGQYQEYRSSLDLVDAEIQQRQADIQAARIQVMSLQKTLPIATKLASDYENLLK
KQYIARHAYLEKEQARLDLERQLSVQQASVLQSTAARQEAERRREGVVAQTRRAMLDLLQQADQKIASFNQDLTKARYQE
DLTTLEAPVDGTVQQLAVHTVGGVVTPAQPLMVLVPDGQPVEVEAMLENKDVGFVRAGQAVTVKVETFTFTKYGTIEGEV
ISVSNDAIEDEKRGLIYSSKIRLNSDTLNVNGVDIKLSPGMAVTAEVTTNKRRVIEYFLSPLQQHASESFRER
>Mature_472_residues
SNAESTGLLQRYRRVWRQSWRHRREMDAPKRLAHEVQFLPAALELQDKPSHPAPRVFMWAIMFFAALALLWACLGKIDVV
ATASGKIIPSGKTKTIQSSETAVVKAIHVRDGQSVKAGQLLLELDSTSADADVGRVRSDLLAARIDSARAAAMLDAINQR
KPPRDLTGTILDADPMHVLAAERWLQGQYQEYRSSLDLVDAEIQQRQADIQAARIQVMSLQKTLPIATKLASDYENLLKK
QYIARHAYLEKEQARLDLERQLSVQQASVLQSTAARQEAERRREGVVAQTRRAMLDLLQQADQKIASFNQDLTKARYQED
LTTLEAPVDGTVQQLAVHTVGGVVTPAQPLMVLVPDGQPVEVEAMLENKDVGFVRAGQAVTVKVETFTFTKYGTIEGEVI
SVSNDAIEDEKRGLIYSSKIRLNSDTLNVNGVDIKLSPGMAVTAEVTTNKRRVIEYFLSPLQQHASESFRER

Specific function: Involved in the transport of the hemolysin/leukotoxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 52688; Mature: 52557

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAESTGLLQRYRRVWRQSWRHRREMDAPKRLAHEVQFLPAALELQDKPSHPAPRVFMW
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AIMFFAALALLWACLGKIDVVATASGKIIPSGKTKTIQSSETAVVKAIHVRDGQSVKAGQ
HHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCEECCCCCEEEEEEEECCCCCCCCCE
LLLELDSTSADADVGRVRSDLLAARIDSARAAAMLDAINQRKPPRDLTGTILDADPMHVL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHH
AAERWLQGQYQEYRSSLDLVDAEIQQRQADIQAARIQVMSLQKTLPIATKLASDYENLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQYIARHAYLEKEQARLDLERQLSVQQASVLQSTAARQEAERRREGVVAQTRRAMLDLLQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QADQKIASFNQDLTKARYQEDLTTLEAPVDGTVQQLAVHTVGGVVTPAQPLMVLVPDGQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
VEVEAMLENKDVGFVRAGQAVTVKVETFTFTKYGTIEGEVISVSNDAIEDEKRGLIYSSK
EEEEEEECCCCCCEEECCCEEEEEEEEEEEEEECCCCCEEEECCCCCCCHHHCCCEEEEE
IRLNSDTLNVNGVDIKLSPGMAVTAEVTTNKRRVIEYFLSPLQQHASESFRER
EEECCCEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNAESTGLLQRYRRVWRQSWRHRREMDAPKRLAHEVQFLPAALELQDKPSHPAPRVFMW
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AIMFFAALALLWACLGKIDVVATASGKIIPSGKTKTIQSSETAVVKAIHVRDGQSVKAGQ
HHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCEECCCCCEEEEEEEECCCCCCCCCE
LLLELDSTSADADVGRVRSDLLAARIDSARAAAMLDAINQRKPPRDLTGTILDADPMHVL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHH
AAERWLQGQYQEYRSSLDLVDAEIQQRQADIQAARIQVMSLQKTLPIATKLASDYENLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQYIARHAYLEKEQARLDLERQLSVQQASVLQSTAARQEAERRREGVVAQTRRAMLDLLQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QADQKIASFNQDLTKARYQEDLTTLEAPVDGTVQQLAVHTVGGVVTPAQPLMVLVPDGQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
VEVEAMLENKDVGFVRAGQAVTVKVETFTFTKYGTIEGEVISVSNDAIEDEKRGLIYSSK
EEEEEEECCCCCCEEECCCEEEEEEEEEEEEEECCCCCEEEECCCCCCCHHHCCCEEEEE
IRLNSDTLNVNGVDIKLSPGMAVTAEVTTNKRRVIEYFLSPLQQHASESFRER
EEECCCEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2402458; 1961107 [H]