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The map label for this gene is glpR [H]

Identifier: 66046288

GI number: 66046288

Start: 3654763

End: 3655599

Strand: Reverse

Name: glpR [H]

Synonym: Psyr_3057

Alternate gene names: 66046288

Gene position: 3655599-3654763 (Counterclockwise)

Preceding gene: 66046289

Following gene: 66046287

Centisome position: 59.99

GC content: 59.38

Gene sequence:

>837_bases
ATGTCGCTCTTGCACGCAGATCAGCGGCCCAAGGGCCCGGACACTGGAGTCATCACTTTGCAACGGAATGTCACCCCCAT
GCTCAATCAGCCGCGTCTGGACGAAATCATGCGCCTGCTCGCTCAACAGCAGCGCGTCAAGGCGTCGGACCTTGCACAAT
TGCTGTTCGTCTCCGAAGAGACCATCCGCCGCGACTTCAAGCATCTGGAGGAGGAGGGCAGGTTAAGGCGAATTCACGGC
GGTGCCATTCTGCCCAGGTCCAGCGAAGAATTGCCGTTGCAGGAGCGCAGCAGGCTCAAGCCTCGCGCCAAGGCGTGCAT
CGCTGTGCGCGCCGCGCAACTGGTCAGCGAAGGCATGGCGATCTTTCTCGACACCGGTACCTCGACGCTGGCGCTGGCCC
AGCAACTGACCCGGTTCAGTCAGTTGAAGATCATCACCAATTCGCTGGACATCGCCCAGCTGATATCGCACCAGAGCGAC
AATCAGGTTCTGGTTGCGCCCGGTGATGTGCGGCGCACCGACAACGCCTTGATCGGTCCCCATACGCTGGAATTCGCCCG
ACAGTTTCACTACGACATTGCCTTCATGGGCATCGGCGGCATTGATCTGGACTTCGGCCTGATGGATTACCAGGAGCCGG
AAGCCATGTTGCGCAGGACGCTGGTCAGGCATTGCACGCGCAGTGTGGTGCTGGCCGACGATGGCAAGTTCGGTCATCGC
ACCTTTATCAATACCCTGCCATTTGCCGCGATCACGACGTTGGTCACCAATCGCGCGCTATCCGACGAGTTTGCGACACG
CCTGGAGAAAGATCATGTCGACACCCTCTATTCCTGA

Upstream 100 bases:

>100_bases
GCCCACGCTTTGCCGATGCCCAGGTGCTGCAGTTCTGTGCCGCTGTAGAAGCCATTGCGCCCTGGGACCAGCACCTGCCA
CCGGTTTCGGGGCAATAGAC

Downstream 100 bases:

>100_bases
GCTGATCGAGCCGAGCGCAACTGATCTGGCAGCGTTCGAAGCCTTGTTTCGGCAAAGCTCGGCCATCGGTGCGACTCCGG
CCGGAGGCCTGCATCGGCTG

Product: regulatory protein, DeoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSLLHADQRPKGPDTGVITLQRNVTPMLNQPRLDEIMRLLAQQQRVKASDLAQLLFVSEETIRRDFKHLEEEGRLRRIHG
GAILPRSSEELPLQERSRLKPRAKACIAVRAAQLVSEGMAIFLDTGTSTLALAQQLTRFSQLKIITNSLDIAQLISHQSD
NQVLVAPGDVRRTDNALIGPHTLEFARQFHYDIAFMGIGGIDLDFGLMDYQEPEAMLRRTLVRHCTRSVVLADDGKFGHR
TFINTLPFAAITTLVTNRALSDEFATRLEKDHVDTLYS

Sequences:

>Translated_278_residues
MSLLHADQRPKGPDTGVITLQRNVTPMLNQPRLDEIMRLLAQQQRVKASDLAQLLFVSEETIRRDFKHLEEEGRLRRIHG
GAILPRSSEELPLQERSRLKPRAKACIAVRAAQLVSEGMAIFLDTGTSTLALAQQLTRFSQLKIITNSLDIAQLISHQSD
NQVLVAPGDVRRTDNALIGPHTLEFARQFHYDIAFMGIGGIDLDFGLMDYQEPEAMLRRTLVRHCTRSVVLADDGKFGHR
TFINTLPFAAITTLVTNRALSDEFATRLEKDHVDTLYS
>Mature_277_residues
SLLHADQRPKGPDTGVITLQRNVTPMLNQPRLDEIMRLLAQQQRVKASDLAQLLFVSEETIRRDFKHLEEEGRLRRIHGG
AILPRSSEELPLQERSRLKPRAKACIAVRAAQLVSEGMAIFLDTGTSTLALAQQLTRFSQLKIITNSLDIAQLISHQSDN
QVLVAPGDVRRTDNALIGPHTLEFARQFHYDIAFMGIGGIDLDFGLMDYQEPEAMLRRTLVRHCTRSVVLADDGKFGHRT
FINTLPFAAITTLVTNRALSDEFATRLEKDHVDTLYS

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=226, Percent_Identity=32.7433628318584, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=29.1338582677165, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788069, Length=253, Percent_Identity=28.0632411067194, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789059, Length=244, Percent_Identity=27.0491803278689, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789519, Length=248, Percent_Identity=27.4193548387097, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=27.6679841897233, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787540, Length=212, Percent_Identity=31.6037735849057, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789170, Length=214, Percent_Identity=27.5700934579439, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790753, Length=243, Percent_Identity=22.6337448559671, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 31276; Mature: 31145

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLHADQRPKGPDTGVITLQRNVTPMLNQPRLDEIMRLLAQQQRVKASDLAQLLFVSEE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TIRRDFKHLEEEGRLRRIHGGAILPRSSEELPLQERSRLKPRAKACIAVRAAQLVSEGMA
HHHHHHHHHHHCCCEEEECCCEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCE
IFLDTGTSTLALAQQLTRFSQLKIITNSLDIAQLISHQSDNQVLVAPGDVRRTDNALIGP
EEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCCCCCCEECC
HTLEFARQFHYDIAFMGIGGIDLDFGLMDYQEPEAMLRRTLVRHCTRSVVLADDGKFGHR
HHHHHHHHHHCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHH
TFINTLPFAAITTLVTNRALSDEFATRLEKDHVDTLYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLHADQRPKGPDTGVITLQRNVTPMLNQPRLDEIMRLLAQQQRVKASDLAQLLFVSEE
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TIRRDFKHLEEEGRLRRIHGGAILPRSSEELPLQERSRLKPRAKACIAVRAAQLVSEGMA
HHHHHHHHHHHCCCEEEECCCEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCE
IFLDTGTSTLALAQQLTRFSQLKIITNSLDIAQLISHQSDNQVLVAPGDVRRTDNALIGP
EEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCCCCCCEECC
HTLEFARQFHYDIAFMGIGGIDLDFGLMDYQEPEAMLRRTLVRHCTRSVVLADDGKFGHR
HHHHHHHHHHCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHH
TFINTLPFAAITTLVTNRALSDEFATRLEKDHVDTLYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]