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The map label for this gene is 66046255

Identifier: 66046255

GI number: 66046255

Start: 3621563

End: 3622699

Strand: Direct

Name: 66046255

Synonym: Psyr_3024

Alternate gene names: NA

Gene position: 3621563-3622699 (Clockwise)

Preceding gene: 66046254

Following gene: 66046257

Centisome position: 59.43

GC content: 59.81

Gene sequence:

>1137_bases
TTGACTCTCACTATCGGTTCAGATTTCGACAGCGGCAACATTCAGGTTCTCGACGCAAGCGACCCGGCGCATATCAGACT
GGCGATTCGGCCCGACACGCAAAGCGCGCATTTCCAGTGGTTTCATTTCAAGGCAGACGGCCTGAACGTCGGCCAGACCT
ACGGCTTCAGCCTCACCAATGCCAGCCAATCCACTTTCAACAGTGCCTGGAGCGGCTACAACGCCGTGGCGTCCTACGAC
CATCAGAACTGGTTTCGTGTCGCGTCGGATTTCGACGGCAAGGCGCTGAATTTCAGCCTGGCCGCGGAGCAACCGCAGGT
CTGGTTTGCGTACTTCGAACCCTACAGCCGTGAACGCCATGACTGGCTGATCGAACAGGCGCAGGAAAAAGCCGGTACAC
AGTTGCTGGCTGTCGGCAAAAGCGTCGAGGGCCGGGATATTCAGCTGCTGCGCAAAGGTGACGGTGCCGAAGGCAAACGC
AAGATCTGGATGATTGCCCAGCAGCACCCTGGCGAACACATGGCCGAATGGTTCATGGAGGGCGTGATCGAACGCCTCCA
GCAAAAGGATGACGCCGCGCTGCAGCAATTGCTGGCCGAGGCAGACCTGTACCTGGTGCCGAACGTCAACCCGGACGGGG
CCTTTCATGGCCACTTGCGCACCAACGCCAGCGGCAAGGACCTTAACCGTGCCTGGCAGGACAGTACCGAAGCGCTGAGC
CCGGAAGTGTCCTTCGTCAGGCAGCAGATGGAAAAATACGGCGTGGACATGTTCCTCGACGTGCACGGTGACGAGGAAAT
CCCCTACGTATTCACCGCCGCCTGCGAAGGCAATCCGGGGTATACCGCACAGCAACGCCAGCTTGAAGAGCGCTTTCGCA
GCCGCCTGTGCGAGGTCAGCGACAACTTCCAGACGGCTCATGGCTACCCACGCGGCGCACCCGGTCAGGCCAACATGAAC
CTGGCCGCCAATGCTGTGGGCGAACGCTACAAGTGCCTGTCACTGACCCTGGAAATGCCCTTCAAGGATCACGACAACGC
GCCAGACCCAGTCACCGGCTGGTCAGGCAAGCGTTCCGCGCAACTGGCCGGGGACATACTGACCGTGCTGTCCGAGATGG
TAAAAGAGCTGCGTTAA

Upstream 100 bases:

>100_bases
CGCGCAGATGACCGTTGCAGTGAAGTTTACGTCGCAGGACGCGATGTCGATCGGTGTACAGTAGCGGCCTGAAAAGGCAT
CTACGCAGCAGGCACCTATC

Downstream 100 bases:

>100_bases
GGGCTCTGCTGTCTTCAGGCAAACCGAAATGCCCATCTACGCGTGGGCATTTTTGTTTGCGCTGGCCGCACGGCGTACGA
TCAGACTGGCCAGCGCGATC

Product: peptidase M14, carboxypeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTLTIGSDFDSGNIQVLDASDPAHIRLAIRPDTQSAHFQWFHFKADGLNVGQTYGFSLTNASQSTFNSAWSGYNAVASYD
HQNWFRVASDFDGKALNFSLAAEQPQVWFAYFEPYSRERHDWLIEQAQEKAGTQLLAVGKSVEGRDIQLLRKGDGAEGKR
KIWMIAQQHPGEHMAEWFMEGVIERLQQKDDAALQQLLAEADLYLVPNVNPDGAFHGHLRTNASGKDLNRAWQDSTEALS
PEVSFVRQQMEKYGVDMFLDVHGDEEIPYVFTAACEGNPGYTAQQRQLEERFRSRLCEVSDNFQTAHGYPRGAPGQANMN
LAANAVGERYKCLSLTLEMPFKDHDNAPDPVTGWSGKRSAQLAGDILTVLSEMVKELR

Sequences:

>Translated_378_residues
MTLTIGSDFDSGNIQVLDASDPAHIRLAIRPDTQSAHFQWFHFKADGLNVGQTYGFSLTNASQSTFNSAWSGYNAVASYD
HQNWFRVASDFDGKALNFSLAAEQPQVWFAYFEPYSRERHDWLIEQAQEKAGTQLLAVGKSVEGRDIQLLRKGDGAEGKR
KIWMIAQQHPGEHMAEWFMEGVIERLQQKDDAALQQLLAEADLYLVPNVNPDGAFHGHLRTNASGKDLNRAWQDSTEALS
PEVSFVRQQMEKYGVDMFLDVHGDEEIPYVFTAACEGNPGYTAQQRQLEERFRSRLCEVSDNFQTAHGYPRGAPGQANMN
LAANAVGERYKCLSLTLEMPFKDHDNAPDPVTGWSGKRSAQLAGDILTVLSEMVKELR
>Mature_377_residues
TLTIGSDFDSGNIQVLDASDPAHIRLAIRPDTQSAHFQWFHFKADGLNVGQTYGFSLTNASQSTFNSAWSGYNAVASYDH
QNWFRVASDFDGKALNFSLAAEQPQVWFAYFEPYSRERHDWLIEQAQEKAGTQLLAVGKSVEGRDIQLLRKGDGAEGKRK
IWMIAQQHPGEHMAEWFMEGVIERLQQKDDAALQQLLAEADLYLVPNVNPDGAFHGHLRTNASGKDLNRAWQDSTEALSP
EVSFVRQQMEKYGVDMFLDVHGDEEIPYVFTAACEGNPGYTAQQRQLEERFRSRLCEVSDNFQTAHGYPRGAPGQANMNL
AANAVGERYKCLSLTLEMPFKDHDNAPDPVTGWSGKRSAQLAGDILTVLSEMVKELR

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31657119, Length=312, Percent_Identity=24.3589743589744, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI222352158, Length=311, Percent_Identity=23.4726688102894, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI190194403, Length=334, Percent_Identity=24.8502994011976, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI170763513, Length=323, Percent_Identity=24.4582043343653, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI120444924, Length=326, Percent_Identity=25.4601226993865, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115533904, Length=374, Percent_Identity=27.5401069518717, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193202888, Length=309, Percent_Identity=25.5663430420712, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641847, Length=322, Percent_Identity=25.1552795031056, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI161077807, Length=322, Percent_Identity=24.8447204968944, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571179, Length=322, Percent_Identity=24.8447204968944, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24641845, Length=322, Percent_Identity=24.8447204968944, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24651466, Length=282, Percent_Identity=27.3049645390071, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 42368; Mature: 42237

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTIGSDFDSGNIQVLDASDPAHIRLAIRPDTQSAHFQWFHFKADGLNVGQTYGFSLTN
CEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEECC
ASQSTFNSAWSGYNAVASYDHQNWFRVASDFDGKALNFSLAAEQPQVWFAYFEPYSRERH
CCHHHHHHHCCCCCHHCCCCCCCHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCHH
DWLIEQAQEKAGTQLLAVGKSVEGRDIQLLRKGDGAEGKRKIWMIAQQHPGEHMAEWFME
HHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHH
GVIERLQQKDDAALQQLLAEADLYLVPNVNPDGAFHGHLRTNASGKDLNRAWQDSTEALS
HHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCEECEEECCCCCCHHHHHHHCHHHHCC
PEVSFVRQQMEKYGVDMFLDVHGDEEIPYVFTAACEGNPGYTAQQRQLEERFRSRLCEVS
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
DNFQTAHGYPRGAPGQANMNLAANAVGERYKCLSLTLEMPFKDHDNAPDPVTGWSGKRSA
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCH
QLAGDILTVLSEMVKELR
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTIGSDFDSGNIQVLDASDPAHIRLAIRPDTQSAHFQWFHFKADGLNVGQTYGFSLTN
EEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEECC
ASQSTFNSAWSGYNAVASYDHQNWFRVASDFDGKALNFSLAAEQPQVWFAYFEPYSRERH
CCHHHHHHHCCCCCHHCCCCCCCHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCHH
DWLIEQAQEKAGTQLLAVGKSVEGRDIQLLRKGDGAEGKRKIWMIAQQHPGEHMAEWFME
HHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHH
GVIERLQQKDDAALQQLLAEADLYLVPNVNPDGAFHGHLRTNASGKDLNRAWQDSTEALS
HHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCEECEEECCCCCCHHHHHHHCHHHHCC
PEVSFVRQQMEKYGVDMFLDVHGDEEIPYVFTAACEGNPGYTAQQRQLEERFRSRLCEVS
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
DNFQTAHGYPRGAPGQANMNLAANAVGERYKCLSLTLEMPFKDHDNAPDPVTGWSGKRSA
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCH
QLAGDILTVLSEMVKELR
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]