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The map label for this gene is ycsE [H]

Identifier: 66046218

GI number: 66046218

Start: 3578605

End: 3579414

Strand: Reverse

Name: ycsE [H]

Synonym: Psyr_2987

Alternate gene names: 66046218

Gene position: 3579414-3578605 (Counterclockwise)

Preceding gene: 66046219

Following gene: 66046217

Centisome position: 58.74

GC content: 59.88

Gene sequence:

>810_bases
ATGTCTGAACTGCCTGTACAGTTCCTGTTGTCCGACATCGACGGCACGTTACTGCGCCGTGATCACAGCCTTAGCCAAGC
CAATATCGACGCCGTCAAGCGCCTGCGTAATGCCGGCGTTCACTTCACGCTGGCCAGCAGTCGCCCGCCCAGGGCCATGC
GCCAGGTAATCGAAGCGTTGAGTGTGGATCTGCCCACCGTGGCGTTCAATGGCGGCACCATCACCCATCCTGATGGCAGC
CTGCTGGTTGCTCATCGCATTGACCCGCGCGCCGTTCGCATTTGTCTGGAGTTGTTTGCCGGGCAGAACGTTGCCATCTG
GGTGTTTGCCGATGATCAGTGGCTGCTGCTCGATCCTCACGCCGATTACGTCGATCATGAGCTCCGTGCACTGGGCTATG
GCTATGTTCAGGTCGAGAGTTTCGAGCCGTATCTGGATCGCGTCGACAAGATCGTCGCGGCCAGCGCCGATTTCGAGTTG
CTCAAGACCCTTGAGGCGCAGCTCAATCCGCAGATCGAAGGGCTCGCGCTGGCGGCCCGTTCGCAAAAATACTACCTGGA
TGTGACTGCGCTGGAGGCCAACAAGGGTTCCGCTCTGGTCGCGCTGGCGGACTATCTGGGCGTCGACCTGTCGCGTACGG
CGGCCATAGGCGACGGCGGTAACGACGTGGCGATGTTCCACAAGGCAGGCTTGTCGATTGCGATGGGGCAGGGCGAGCAG
ACAGTCAAGGGACAGGCTGATCATGTTACTGATAGCAATGAGCAGGACGGAGTGGCCAACGCCATCGAGCGTTACATTCT
GAGCGCCTGA

Upstream 100 bases:

>100_bases
GCCGCGCAGCCGCAAGTGCAGCTTTACGAGGCTGGCAAGGATGGCCCGCAAGCGGGTGAAGAGCTGCTGAGTCGTGACGG
TCGGGAATGGAGAGAATTGA

Downstream 100 bases:

>100_bases
CCGAACGGTGTTCCCACGTTAACGAATCATCATCACGACGGGCATTTCTGAATGGCTGCACTGATCGAAGACTACGCATT
GCTGGGCAACTGCGAGACGG

Product: Cof protein/HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSELPVQFLLSDIDGTLLRRDHSLSQANIDAVKRLRNAGVHFTLASSRPPRAMRQVIEALSVDLPTVAFNGGTITHPDGS
LLVAHRIDPRAVRICLELFAGQNVAIWVFADDQWLLLDPHADYVDHELRALGYGYVQVESFEPYLDRVDKIVAASADFEL
LKTLEAQLNPQIEGLALAARSQKYYLDVTALEANKGSALVALADYLGVDLSRTAAIGDGGNDVAMFHKAGLSIAMGQGEQ
TVKGQADHVTDSNEQDGVANAIERYILSA

Sequences:

>Translated_269_residues
MSELPVQFLLSDIDGTLLRRDHSLSQANIDAVKRLRNAGVHFTLASSRPPRAMRQVIEALSVDLPTVAFNGGTITHPDGS
LLVAHRIDPRAVRICLELFAGQNVAIWVFADDQWLLLDPHADYVDHELRALGYGYVQVESFEPYLDRVDKIVAASADFEL
LKTLEAQLNPQIEGLALAARSQKYYLDVTALEANKGSALVALADYLGVDLSRTAAIGDGGNDVAMFHKAGLSIAMGQGEQ
TVKGQADHVTDSNEQDGVANAIERYILSA
>Mature_268_residues
SELPVQFLLSDIDGTLLRRDHSLSQANIDAVKRLRNAGVHFTLASSRPPRAMRQVIEALSVDLPTVAFNGGTITHPDGSL
LVAHRIDPRAVRICLELFAGQNVAIWVFADDQWLLLDPHADYVDHELRALGYGYVQVESFEPYLDRVDKIVAASADFELL
KTLEAQLNPQIEGLALAARSQKYYLDVTALEANKGSALVALADYLGVDLSRTAAIGDGGNDVAMFHKAGLSIAMGQGEQT
VKGQADHVTDSNEQDGVANAIERYILSA

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=274, Percent_Identity=28.4671532846715, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI48994981, Length=271, Percent_Identity=29.8892988929889, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87081741, Length=247, Percent_Identity=29.1497975708502, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786982, Length=271, Percent_Identity=24.3542435424354, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081790, Length=263, Percent_Identity=22.0532319391635, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 29206; Mature: 29075

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELPVQFLLSDIDGTLLRRDHSLSQANIDAVKRLRNAGVHFTLASSRPPRAMRQVIEAL
CCCCCHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
SVDLPTVAFNGGTITHPDGSLLVAHRIDPRAVRICLELFAGQNVAIWVFADDQWLLLDPH
CCCCCEEEECCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCEEEECCC
ADYVDHELRALGYGYVQVESFEPYLDRVDKIVAASADFELLKTLEAQLNPQIEGLALAAR
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEC
SQKYYLDVTALEANKGSALVALADYLGVDLSRTAAIGDGGNDVAMFHKAGLSIAMGQGEQ
CCEEEEEEEEEECCCCCEEEEEHHHHCCCCHHEEEECCCCCCEEEEECCCCEEEECCCCC
TVKGQADHVTDSNEQDGVANAIERYILSA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SELPVQFLLSDIDGTLLRRDHSLSQANIDAVKRLRNAGVHFTLASSRPPRAMRQVIEAL
CCCCHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
SVDLPTVAFNGGTITHPDGSLLVAHRIDPRAVRICLELFAGQNVAIWVFADDQWLLLDPH
CCCCCEEEECCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCEEEECCC
ADYVDHELRALGYGYVQVESFEPYLDRVDKIVAASADFELLKTLEAQLNPQIEGLALAAR
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEC
SQKYYLDVTALEANKGSALVALADYLGVDLSRTAAIGDGGNDVAMFHKAGLSIAMGQGEQ
CCEEEEEEEEEECCCCCEEEEEHHHHCCCCHHEEEECCCCCCEEEEECCCCEEEECCCCC
TVKGQADHVTDSNEQDGVANAIERYILSA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]