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The map label for this gene is ahpC [H]

Identifier: 66046206

GI number: 66046206

Start: 3567794

End: 3568357

Strand: Reverse

Name: ahpC [H]

Synonym: Psyr_2975

Alternate gene names: 66046206

Gene position: 3568357-3567794 (Counterclockwise)

Preceding gene: 66046207

Following gene: 66046205

Centisome position: 58.56

GC content: 56.21

Gene sequence:

>564_bases
ATGCCTATCATCAACAGCCAAGTAAAACCGTTCAAGGCTACCGCATTCAAGAACGGCGCTTTCGTTGACGTCTCGGACGC
TGACTTCAAAGGCAAGTGGTCTGTCGTATTCTTCTACCCGGCCGACTTCACCTTCGTATGCCCGACCGAGCTGGAAGACC
TGGCTGACAACTACGAAGAGTTCAAGAAGCTGGGCGTTGAGATCTACAGTGTCTCGACTGACACCCACTTCGCTCACGCT
GCATGGCACAACACTTCGCCAGCCATCGGCAAGATCCAGTACACCATGATCGGTGACCCGACCCTGACCATCTCCCGCAA
CTTCGACGTACTGATCGAAGAAGCCGGTCTGGCGGATCGCGGTACTTTCGTGATCAACCCTGAAGGTCAGATCAAAATCG
TCGAGCTGAACGACGGCGGTGTTGGCCGTGACGCTTCCGAGCTGCTGCGCAAGATCAAGGCTGCTCAGTACGTTGCCGCT
CACCCGGGCGAAGTCTGCCCAGCCAAGTGGAAAGAAGGCGAAGCTACTCTGGCTCCGTCCCTGGACCTGGTTGGCAAGAT
CTGA

Upstream 100 bases:

>100_bases
TCAGTGACATCAGGTTTGCCAATGAGCGATTGTCATCGATCATGCGTAAGCTTCACTTCATCGAATTCACAACCCATCCA
ACCCATCAGGAGATATACCG

Downstream 100 bases:

>100_bases
GTCGCATGAATCGGCTAGGGGCGTTGAGCTCTTGAGCAAGTAAACCGCATCGCCCCAAAAAACGCCCGGGCGGTCATCGC
CTGGGCGTTGTTATTTCTAC

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPIINSQVKPFKATAFKNGAFVDVSDADFKGKWSVVFFYPADFTFVCPTELEDLADNYEEFKKLGVEIYSVSTDTHFAHA
AWHNTSPAIGKIQYTMIGDPTLTISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAA
HPGEVCPAKWKEGEATLAPSLDLVGKI

Sequences:

>Translated_187_residues
MPIINSQVKPFKATAFKNGAFVDVSDADFKGKWSVVFFYPADFTFVCPTELEDLADNYEEFKKLGVEIYSVSTDTHFAHA
AWHNTSPAIGKIQYTMIGDPTLTISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAA
HPGEVCPAKWKEGEATLAPSLDLVGKI
>Mature_186_residues
PIINSQVKPFKATAFKNGAFVDVSDADFKGKWSVVFFYPADFTFVCPTELEDLADNYEEFKKLGVEIYSVSTDTHFAHAA
WHNTSPAIGKIQYTMIGDPTLTISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAH
PGEVCPAKWKEGEATLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=49.1620111731844, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=47.8021978021978, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=45.1428571428571, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=44.5714285714286, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=44.5714285714286, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=44.5714285714286, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=41.6666666666667, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=53.2467532467532, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI4758638, Length=167, Percent_Identity=29.3413173652695, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=68.4491978609626, Blast_Score=288, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=44.6927374301676, Blast_Score=158, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=44.2528735632184, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=44.2528735632184, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=28.0487804878049, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=37.3626373626374, Blast_Score=130, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=35.9116022099448, Blast_Score=130, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6319407, Length=158, Percent_Identity=31.0126582278481, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=41.8079096045198, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=40.5555555555556, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=40.5555555555556, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=39.5604395604396, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=40.3314917127072, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=40.3314917127072, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=31.1688311688312, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.746835443038, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652436, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.746835443038, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20484; Mature: 20353

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINSQVKPFKATAFKNGAFVDVSDADFKGKWSVVFFYPADFTFVCPTELEDLADNYEE
CCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FKKLGVEIYSVSTDTHFAHAAWHNTSPAIGKIQYTMIGDPTLTISRNFDVLIEEAGLADR
HHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCEEEEEECCCCCC
GTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC
>Mature Secondary Structure 
PIINSQVKPFKATAFKNGAFVDVSDADFKGKWSVVFFYPADFTFVCPTELEDLADNYEE
CCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FKKLGVEIYSVSTDTHFAHAAWHNTSPAIGKIQYTMIGDPTLTISRNFDVLIEEAGLADR
HHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCEEEEEECCCCCC
GTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]