Click here to switch to the map view.

The map label for this gene is bepF [H]

Identifier: 66046198

GI number: 66046198

Start: 3556381

End: 3557622

Strand: Direct

Name: bepF [H]

Synonym: Psyr_2967

Alternate gene names: 66046198

Gene position: 3556381-3557622 (Clockwise)

Preceding gene: 66046196

Following gene: 66046199

Centisome position: 58.36

GC content: 63.04

Gene sequence:

>1242_bases
ATGCACCAGACAATCAGCCATCTGCGCTATCCTCTCACCGCCCTCGCCTTGATCGTCATCAGTGCCTGCGGCCGTGCGCC
GGAAGCCACCAGTGCGCCTGGCGCGGCCAAGGTCAGTGTGGCCAAGGTACTGGAGCAGCCAGTCAACGAGTGGGATGAAT
TCACCGGTCGTCTCGAAGCACCTGAAACGGTCGAAGTGCGTCCAAGGGTCTCCGGCCAGATCGATCAGGTAGCCTTCACC
GACGGCGCGCTGGTCAAGAAAGGCGATCTGCTGTTCCAGATCGATCCTCGCCCTTTCCAGTCGGAAGTCCGCCGCCTCGA
AGCCCAGTTGCAACAGGCCCGCGCAGTTGCTTCGCGCAGTGACAGCGAAGCGCAGCGCGGTGAGCGTCTGCGCAGCAACA
ATGCGATTTCCGCCGAGCTGGCCGAATCGCGTACCACCTCGGCGCAGGAAGCCAAGGCCGGTGTCGCGGCCATCCAGGCG
CAACTGGATCTGGCTCGACTGAACCTCAGTTTCACCCGGGTCACCGCACCGATTTCAGGCCGCGTAAGCCGTGCCGAAAT
CACCGCTGGCAACATTGTTACCGCCGATGTCACCGCCCTGACCAGCGTGGTTTCCACCGACAAGGTCTACGCCTACTTCG
ACGCAGACGAGCGCGTGTTCCTCAAATACACCGAACTGGCCCGCAAAGGCCAGCGCGGTCAGACCACGCCGGTGTACCTG
GGGCTGTCCAACGAACCCGGCAACCCGCACCTGGGCCAGATGAACTTTGTCGACAACCAGGTCAACCCGAGGACCGGCAC
CATTCGTGGCCGCGCCGTGTTCGATAACGCCGACGGTGCGTTTACCCCCGGCCTGTATGCACGCCTGAAACTGGTGGGCA
GCGGCACTTACTCGGCCGTGCTGATCAATGACGAAGCAGTGGGCACCGACCTGGGCAAGAAGTTTGTGCTGGTCATGGAC
AAGGACAACAAGCCCGCTTACCGGGCTGTCGAGCTGGGGCCGAAAATCGAAGGCCTGCGCATTGTGCGCAATGGTCTGGC
CAAGGATGACACCATCGTCGTCAAAGGCTTGCAGCGCGTTCGTCCCGGCCAGCCTGTGGACCCTGAAGTCACTCCGATGG
CCAGCGCCGACACCCTCGCCGCACTGCTCAAACAACGCCAGGCCCTCGAAGCCAGCAACCTGCCACAAGTGGCGCCCAAA
GCGGCCGTCAAAATCGCCAGCGCTGCCGCGCCGCGCGGCTAA

Upstream 100 bases:

>100_bases
ATCATTGTCGGTGATAGTAACCTTCGGTTTATTCGATTCGTTAATAACACCCCGTGCGCAACAGAATCCGCCCCATTCTT
CACTATTGGCGGAACTTCCC

Downstream 100 bases:

>100_bases
GGGACTCGTCCGATGAACTTCTCCAAATTCTTTATTTCACGGCCGATCTTCGCCGCAGTGCTGTCGCTGCTGATCCTGAT
CGCCGGTGCCATCTCGCTGT

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MHQTISHLRYPLTALALIVISACGRAPEATSAPGAAKVSVAKVLEQPVNEWDEFTGRLEAPETVEVRPRVSGQIDQVAFT
DGALVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRSDSEAQRGERLRSNNAISAELAESRTTSAQEAKAGVAAIQA
QLDLARLNLSFTRVTAPISGRVSRAEITAGNIVTADVTALTSVVSTDKVYAYFDADERVFLKYTELARKGQRGQTTPVYL
GLSNEPGNPHLGQMNFVDNQVNPRTGTIRGRAVFDNADGAFTPGLYARLKLVGSGTYSAVLINDEAVGTDLGKKFVLVMD
KDNKPAYRAVELGPKIEGLRIVRNGLAKDDTIVVKGLQRVRPGQPVDPEVTPMASADTLAALLKQRQALEASNLPQVAPK
AAVKIASAAAPRG

Sequences:

>Translated_413_residues
MHQTISHLRYPLTALALIVISACGRAPEATSAPGAAKVSVAKVLEQPVNEWDEFTGRLEAPETVEVRPRVSGQIDQVAFT
DGALVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRSDSEAQRGERLRSNNAISAELAESRTTSAQEAKAGVAAIQA
QLDLARLNLSFTRVTAPISGRVSRAEITAGNIVTADVTALTSVVSTDKVYAYFDADERVFLKYTELARKGQRGQTTPVYL
GLSNEPGNPHLGQMNFVDNQVNPRTGTIRGRAVFDNADGAFTPGLYARLKLVGSGTYSAVLINDEAVGTDLGKKFVLVMD
KDNKPAYRAVELGPKIEGLRIVRNGLAKDDTIVVKGLQRVRPGQPVDPEVTPMASADTLAALLKQRQALEASNLPQVAPK
AAVKIASAAAPRG
>Mature_413_residues
MHQTISHLRYPLTALALIVISACGRAPEATSAPGAAKVSVAKVLEQPVNEWDEFTGRLEAPETVEVRPRVSGQIDQVAFT
DGALVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRSDSEAQRGERLRSNNAISAELAESRTTSAQEAKAGVAAIQA
QLDLARLNLSFTRVTAPISGRVSRAEITAGNIVTADVTALTSVVSTDKVYAYFDADERVFLKYTELARKGQRGQTTPVYL
GLSNEPGNPHLGQMNFVDNQVNPRTGTIRGRAVFDNADGAFTPGLYARLKLVGSGTYSAVLINDEAVGTDLGKKFVLVMD
KDNKPAYRAVELGPKIEGLRIVRNGLAKDDTIVVKGLQRVRPGQPVDPEVTPMASADTLAALLKQRQALEASNLPQVAPK
AAVKIASAAAPRG

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=351, Percent_Identity=32.7635327635328, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789665, Length=369, Percent_Identity=30.3523035230352, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786668, Length=331, Percent_Identity=32.9305135951662, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87082036, Length=378, Percent_Identity=27.2486772486773, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081951, Length=136, Percent_Identity=36.7647058823529, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790519, Length=257, Percent_Identity=27.2373540856031, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081796, Length=155, Percent_Identity=31.6129032258064, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789637, Length=201, Percent_Identity=30.8457711442786, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44269; Mature: 44269

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQTISHLRYPLTALALIVISACGRAPEATSAPGAAKVSVAKVLEQPVNEWDEFTGRLEA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PETVEVRPRVSGQIDQVAFTDGALVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRS
CCCEEECCCCCCCCCEEEECCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DSEAQRGERLRSNNAISAELAESRTTSAQEAKAGVAAIQAQLDLARLNLSFTRVTAPISG
CHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
RVSRAEITAGNIVTADVTALTSVVSTDKVYAYFDADERVFLKYTELARKGQRGQTTPVYL
CCEEEEEECCCEEEHHHHHHHHHHCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCEEEE
GLSNEPGNPHLGQMNFVDNQVNPRTGTIRGRAVFDNADGAFTPGLYARLKLVGSGTYSAV
EECCCCCCCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEEECCCEEEE
LINDEAVGTDLGKKFVLVMDKDNKPAYRAVELGPKIEGLRIVRNGLAKDDTIVVKGLQRV
EECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHC
RPGQPVDPEVTPMASADTLAALLKQRQALEASNLPQVAPKAAVKIASAAAPRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHQTISHLRYPLTALALIVISACGRAPEATSAPGAAKVSVAKVLEQPVNEWDEFTGRLEA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PETVEVRPRVSGQIDQVAFTDGALVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRS
CCCEEECCCCCCCCCEEEECCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DSEAQRGERLRSNNAISAELAESRTTSAQEAKAGVAAIQAQLDLARLNLSFTRVTAPISG
CHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
RVSRAEITAGNIVTADVTALTSVVSTDKVYAYFDADERVFLKYTELARKGQRGQTTPVYL
CCEEEEEECCCEEEHHHHHHHHHHCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCEEEE
GLSNEPGNPHLGQMNFVDNQVNPRTGTIRGRAVFDNADGAFTPGLYARLKLVGSGTYSAV
EECCCCCCCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEEECCCEEEE
LINDEAVGTDLGKKFVLVMDKDNKPAYRAVELGPKIEGLRIVRNGLAKDDTIVVKGLQRV
EECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHC
RPGQPVDPEVTPMASADTLAALLKQRQALEASNLPQVAPKAAVKIASAAAPRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]