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The map label for this gene is dppA [H]

Identifier: 66046189

GI number: 66046189

Start: 3545617

End: 3547248

Strand: Direct

Name: dppA [H]

Synonym: Psyr_2958

Alternate gene names: 66046189

Gene position: 3545617-3547248 (Clockwise)

Preceding gene: 66046188

Following gene: 66046190

Centisome position: 58.18

GC content: 60.6

Gene sequence:

>1632_bases
ATGACCCGGCGCCCGCTCCTCTCGCGCCTGCTGTTTACCGCCGTCACAGCCATAACCCTGCTTGGCTGCTCACCTTCCGG
CCAGGACAACCAGGCAGCCACAACCCTCAAGGTGGCGTTCTTCAGAGACAACACCACGCTGGTCAGCCTTGACCCCTTTC
AGGTTTACTGGCTGGAGCATCGGGTGGTGCTGCGCAATATTGCCGAGTCCCTGACCGATCAGGACCCGCAGACCGGCAAG
ATCATTCCCTGGCTGGCGGAGCGCTGGGAAATCAGTGACAACGCGCTGGAGTACACCTTTCACTTGCGCAAGGACGTGAC
CTTCAGCAACGGCACACGTTTCGACGCTCAAGCGGTGAAGACGGCCTACGACGCGGACAAGTCGTTCGCCGCACAATTGC
CAGCCACCTTCGGCGCCACTTACCTCAAAGGTTACGACCATGCCGAGGTGCTGGACGAGTTCACCATCAAACTGGTGCTG
GCCCAACCCAATGCGGGCTTTCTGCAAGCCACCTCCACCACCAATCTCGCCATCCTGGCTCCAGAGTCCTACGCGCTCAG
CGTCAAGCAGCGCTCGCTGGGTGCAATCATCGGCACCGGGCCATTCGTGCTGGAGCGCTATACCCCGGAAAGCGGTTTGC
GCCTGATCAAACGCAAGGGCTATGCCTGGCCATCGGCCAATGCGCAGAACAAGGGCGAAGCGCATCTGGACGCAGTCGAG
GTCAGCTACGTGCCGGAAGAAAGCGTACGTAACGGCCAGTTCGTTCAGGGGCAGGTCGATATTCTCTGGCCGCGCAACCC
GTTCTCCGAGGTGGATCTCAACCTGTTCAAGTCCAGGGGCGCGACCATTCAAAGCCGGTCGCTGCCAGGACCGGCACTGA
ACCTGTACCCCAACACACGCGGCAATCGCATTCTTGCCGACCGTAACGTGCGCCAGGCTTTGCAAAAGGCAATCGACCGC
AAGACCTATGCAGCGACGGTCTACAACCCGCAGTTCCCGGTGGTCTCCGGTGTCTTCGACATCACTACACCGTTTTACAA
AAACCAGGCCGACAAGCTTGCCTATGATCCTCAGGGTGCCGAGCGCTTGCTCGACCAGGCTGGCTGGCAAAAAAATGCCG
ACGGCTATCGCTACAAGGAGGGCAAACGGCTGAAGCTGGCCTACAACCTGTCACCCGCCGAAACCGCTGGCGATGTACTG
ATCCAGGATCAACTGCGCAAGGTGGGCATCGAGCTCAAGCTCAACGTGGTGACCACCGCCGAATGGGCCGCTGCCAATGC
GGCAGGCAATTATGACCTGACGTACAACTACATGACCCGCGCCGACCCGATCATCCTGCAGACCATCATCGACCCGCGCA
GCGCCAACAGCTCGACTCTGGCGACCAACCTTTACGCGCCGGAAACACTGCCCAGAGCCCTTGCGCTGTTCGACGCCGGA
CTGACCGCCACGCAAAGCGAGCAGCGTGCCCGGGCCTATGGCGAGTTGCAGGACTTGCTGATCGACGAAGGCTCGGCGTT
CCCGGTCTACGAGCGGGTCTGGCAAGCCGCCACGGCGAAAAACGTACGCAACTTCCACTGGACGGCGGAAGGCTTTGCGC
TGTTCAACGACATCGAGTTGGCAACGCCATGA

Upstream 100 bases:

>100_bases
TCAGTGCTGAAGCACTGTGCCTGACTTGAAGAGGACCTTCCATGCGCCGTACACCACCTTCGACTTTCTCAAATGGATTC
GTGACTCGGAGCACAATGCG

Downstream 100 bases:

>100_bases
GCCGCTATATCCTCAGTCGCATCGCGCAAGCGCTGCTGGTACTTTGGGGTGCCTACAGCGTCACCTATTTCATTCTGTAC
CTGCTGCCCGGCGACACCCT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTRRPLLSRLLFTAVTAITLLGCSPSGQDNQAATTLKVAFFRDNTTLVSLDPFQVYWLEHRVVLRNIAESLTDQDPQTGK
IIPWLAERWEISDNALEYTFHLRKDVTFSNGTRFDAQAVKTAYDADKSFAAQLPATFGATYLKGYDHAEVLDEFTIKLVL
AQPNAGFLQATSTTNLAILAPESYALSVKQRSLGAIIGTGPFVLERYTPESGLRLIKRKGYAWPSANAQNKGEAHLDAVE
VSYVPEESVRNGQFVQGQVDILWPRNPFSEVDLNLFKSRGATIQSRSLPGPALNLYPNTRGNRILADRNVRQALQKAIDR
KTYAATVYNPQFPVVSGVFDITTPFYKNQADKLAYDPQGAERLLDQAGWQKNADGYRYKEGKRLKLAYNLSPAETAGDVL
IQDQLRKVGIELKLNVVTTAEWAAANAAGNYDLTYNYMTRADPIILQTIIDPRSANSSTLATNLYAPETLPRALALFDAG
LTATQSEQRARAYGELQDLLIDEGSAFPVYERVWQAATAKNVRNFHWTAEGFALFNDIELATP

Sequences:

>Translated_543_residues
MTRRPLLSRLLFTAVTAITLLGCSPSGQDNQAATTLKVAFFRDNTTLVSLDPFQVYWLEHRVVLRNIAESLTDQDPQTGK
IIPWLAERWEISDNALEYTFHLRKDVTFSNGTRFDAQAVKTAYDADKSFAAQLPATFGATYLKGYDHAEVLDEFTIKLVL
AQPNAGFLQATSTTNLAILAPESYALSVKQRSLGAIIGTGPFVLERYTPESGLRLIKRKGYAWPSANAQNKGEAHLDAVE
VSYVPEESVRNGQFVQGQVDILWPRNPFSEVDLNLFKSRGATIQSRSLPGPALNLYPNTRGNRILADRNVRQALQKAIDR
KTYAATVYNPQFPVVSGVFDITTPFYKNQADKLAYDPQGAERLLDQAGWQKNADGYRYKEGKRLKLAYNLSPAETAGDVL
IQDQLRKVGIELKLNVVTTAEWAAANAAGNYDLTYNYMTRADPIILQTIIDPRSANSSTLATNLYAPETLPRALALFDAG
LTATQSEQRARAYGELQDLLIDEGSAFPVYERVWQAATAKNVRNFHWTAEGFALFNDIELATP
>Mature_542_residues
TRRPLLSRLLFTAVTAITLLGCSPSGQDNQAATTLKVAFFRDNTTLVSLDPFQVYWLEHRVVLRNIAESLTDQDPQTGKI
IPWLAERWEISDNALEYTFHLRKDVTFSNGTRFDAQAVKTAYDADKSFAAQLPATFGATYLKGYDHAEVLDEFTIKLVLA
QPNAGFLQATSTTNLAILAPESYALSVKQRSLGAIIGTGPFVLERYTPESGLRLIKRKGYAWPSANAQNKGEAHLDAVEV
SYVPEESVRNGQFVQGQVDILWPRNPFSEVDLNLFKSRGATIQSRSLPGPALNLYPNTRGNRILADRNVRQALQKAIDRK
TYAATVYNPQFPVVSGVFDITTPFYKNQADKLAYDPQGAERLLDQAGWQKNADGYRYKEGKRLKLAYNLSPAETAGDVLI
QDQLRKVGIELKLNVVTTAEWAAANAAGNYDLTYNYMTRADPIILQTIIDPRSANSSTLATNLYAPETLPRALALFDAGL
TATQSEQRARAYGELQDLLIDEGSAFPVYERVWQAATAKNVRNFHWTAEGFALFNDIELATP

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=365, Percent_Identity=26.8493150684932, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789887, Length=345, Percent_Identity=25.5072463768116, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787052, Length=570, Percent_Identity=21.9298245614035, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787551, Length=470, Percent_Identity=24.2553191489362, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787762, Length=471, Percent_Identity=22.2929936305732, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60321; Mature: 60189

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRPLLSRLLFTAVTAITLLGCSPSGQDNQAATTLKVAFFRDNTTLVSLDPFQVYWLEH
CCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEEEEECCEEEEEECCEEEEEHHH
RVVLRNIAESLTDQDPQTGKIIPWLAERWEISDNALEYTFHLRKDVTFSNGTRFDAQAVK
HHHHHHHHHHHCCCCCCCCCEEHHHHHHEECCCCEEEEEEEEEECCEECCCCCCHHHHHH
TAYDADKSFAAQLPATFGATYLKGYDHAEVLDEFTIKLVLAQPNAGFLQATSTTNLAILA
HHHCCCHHHHHHCCHHHCHHHHCCCCHHHHHHCEEEEEEEECCCCCEEEECCCCCEEEEC
PESYALSVKQRSLGAIIGTGPFVLERYTPESGLRLIKRKGYAWPSANAQNKGEAHLDAVE
CCCEEEEEECCCCCEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
VSYVPEESVRNGQFVQGQVDILWPRNPFSEVDLNLFKSRGATIQSRSLPGPALNLYPNTR
EEECCHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEEEECCCCC
GNRILADRNVRQALQKAIDRKTYAATVYNPQFPVVSGVFDITTPFYKNQADKLAYDPQGA
CCEEEECCHHHHHHHHHHCCCEEEEEEECCCCCHHHCHHHHCCCHHCCCCCCCEECCCHH
ERLLDQAGWQKNADGYRYKEGKRLKLAYNLSPAETAGDVLIQDQLRKVGIELKLNVVTTA
HHHHHHCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEEC
EWAAANAAGNYDLTYNYMTRADPIILQTIIDPRSANSSTLATNLYAPETLPRALALFDAG
HHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
LTATQSEQRARAYGELQDLLIDEGSAFPVYERVWQAATAKNVRNFHWTAEGFALFNDIEL
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECEEE
ATP
CCC
>Mature Secondary Structure 
TRRPLLSRLLFTAVTAITLLGCSPSGQDNQAATTLKVAFFRDNTTLVSLDPFQVYWLEH
CCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEEEEECCEEEEEECCEEEEEHHH
RVVLRNIAESLTDQDPQTGKIIPWLAERWEISDNALEYTFHLRKDVTFSNGTRFDAQAVK
HHHHHHHHHHHCCCCCCCCCEEHHHHHHEECCCCEEEEEEEEEECCEECCCCCCHHHHHH
TAYDADKSFAAQLPATFGATYLKGYDHAEVLDEFTIKLVLAQPNAGFLQATSTTNLAILA
HHHCCCHHHHHHCCHHHCHHHHCCCCHHHHHHCEEEEEEEECCCCCEEEECCCCCEEEEC
PESYALSVKQRSLGAIIGTGPFVLERYTPESGLRLIKRKGYAWPSANAQNKGEAHLDAVE
CCCEEEEEECCCCCEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
VSYVPEESVRNGQFVQGQVDILWPRNPFSEVDLNLFKSRGATIQSRSLPGPALNLYPNTR
EEECCHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEEEECCCCC
GNRILADRNVRQALQKAIDRKTYAATVYNPQFPVVSGVFDITTPFYKNQADKLAYDPQGA
CCEEEECCHHHHHHHHHHCCCEEEEEEECCCCCHHHCHHHHCCCHHCCCCCCCEECCCHH
ERLLDQAGWQKNADGYRYKEGKRLKLAYNLSPAETAGDVLIQDQLRKVGIELKLNVVTTA
HHHHHHCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEEC
EWAAANAAGNYDLTYNYMTRADPIILQTIIDPRSANSSTLATNLYAPETLPRALALFDAG
HHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
LTATQSEQRARAYGELQDLLIDEGSAFPVYERVWQAATAKNVRNFHWTAEGFALFNDIEL
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECEEE
ATP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]