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The map label for this gene is rhtC [H]

Identifier: 66045979

GI number: 66045979

Start: 3329306

End: 3329950

Strand: Reverse

Name: rhtC [H]

Synonym: Psyr_2743

Alternate gene names: 66045979

Gene position: 3329950-3329306 (Counterclockwise)

Preceding gene: 66045980

Following gene: 66045978

Centisome position: 54.65

GC content: 62.17

Gene sequence:

>645_bases
ATGCAAGAAATCACTTTGCTGACCGCCCTCGCTGGGGCGTTCATCGTGTTGATCATCAGCCCTGGTCCGAACTTTCTGGT
CATCACCCAACTCTCGTTCAGCCAGTCACGGCAGCAGGGCATCTGTGCCGGGCTGGGCGTTGCCTCGGGCAGCATCCTCT
GGGCCTTGCTGGCCGCTACCGGGTTGGGGCTGGTGTTTCAGCAGTTGCCATGGCTGCAACCGACCCTGCAATTGCTCGGT
GGTGCCTACCTGACCTGGCTCGGCAGCAAAAGCCTGCGCAGTGCCGGCAGCCAGCCCAAACCCAGGGACATCGCTGCGCT
GGGCATCGGCAGTCTGAGCCGCGCCTATCGTTTCGGCCTGCTGACCAACCTGACCAATCCCAAGGCGCTGGCGTTCTACA
CCAGCGTGTTCACCACCGTGACCACGCCGGGCATGCCGATGTGGGTACGCACTGCGGGTGTATCGATCATCGCGGTGCTG
GCGATTGCCTGGTTCGTGCTGCTCGCCACGCTGTTTTCGATCCCCGCGGTACAGACGCGCTATCAGCGCATGAAAAAGGC
CATCGACATCGTCACCGGCCTGTTCATGATCGCTTTCGGTCTGCGCCTGCTGATCGGGTTGCTGCCTGCTGGCCTCACTC
ACTGA

Upstream 100 bases:

>100_bases
CGAGTCTTGTCTGGATACGCTGACAAACAAAACTTCAAGTGGCATCACATTTCAGTTGAACAAAGCCATTCAAGCTTTTA
ATTAAAAAGGAATTATTACT

Downstream 100 bases:

>100_bases
ACTCACCTGTAAAGGAATACCTGAATGCACCGCAACGACTGGCACTACCCGACTTCCATCCGCGCAGGCGCAGGACGCGT
CAACGAACTGGCCGACGCCT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MQEITLLTALAGAFIVLIISPGPNFLVITQLSFSQSRQQGICAGLGVASGSILWALLAATGLGLVFQQLPWLQPTLQLLG
GAYLTWLGSKSLRSAGSQPKPRDIAALGIGSLSRAYRFGLLTNLTNPKALAFYTSVFTTVTTPGMPMWVRTAGVSIIAVL
AIAWFVLLATLFSIPAVQTRYQRMKKAIDIVTGLFMIAFGLRLLIGLLPAGLTH

Sequences:

>Translated_214_residues
MQEITLLTALAGAFIVLIISPGPNFLVITQLSFSQSRQQGICAGLGVASGSILWALLAATGLGLVFQQLPWLQPTLQLLG
GAYLTWLGSKSLRSAGSQPKPRDIAALGIGSLSRAYRFGLLTNLTNPKALAFYTSVFTTVTTPGMPMWVRTAGVSIIAVL
AIAWFVLLATLFSIPAVQTRYQRMKKAIDIVTGLFMIAFGLRLLIGLLPAGLTH
>Mature_214_residues
MQEITLLTALAGAFIVLIISPGPNFLVITQLSFSQSRQQGICAGLGVASGSILWALLAATGLGLVFQQLPWLQPTLQLLG
GAYLTWLGSKSLRSAGSQPKPRDIAALGIGSLSRAYRFGLLTNLTNPKALAFYTSVFTTVTTPGMPMWVRTAGVSIIAVL
AIAWFVLLATLFSIPAVQTRYQRMKKAIDIVTGLFMIAFGLRLLIGLLPAGLTH

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=208, Percent_Identity=35.0961538461538, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1786522, Length=209, Percent_Identity=32.5358851674641, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788099, Length=208, Percent_Identity=32.2115384615385, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22802; Mature: 22802

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEITLLTALAGAFIVLIISPGPNFLVITQLSFSQSRQQGICAGLGVASGSILWALLAAT
CCHHHHHHHHHHHHEEEEECCCCCEEEEEECCHHHHHHCCCHHHCCCCCHHHHHHHHHHH
GLGLVFQQLPWLQPTLQLLGGAYLTWLGSKSLRSAGSQPKPRDIAALGIGSLSRAYRFGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LTNLTNPKALAFYTSVFTTVTTPGMPMWVRTAGVSIIAVLAIAWFVLLATLFSIPAVQTR
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YQRMKKAIDIVTGLFMIAFGLRLLIGLLPAGLTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQEITLLTALAGAFIVLIISPGPNFLVITQLSFSQSRQQGICAGLGVASGSILWALLAAT
CCHHHHHHHHHHHHEEEEECCCCCEEEEEECCHHHHHHCCCHHHCCCCCHHHHHHHHHHH
GLGLVFQQLPWLQPTLQLLGGAYLTWLGSKSLRSAGSQPKPRDIAALGIGSLSRAYRFGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LTNLTNPKALAFYTSVFTTVTTPGMPMWVRTAGVSIIAVLAIAWFVLLATLFSIPAVQTR
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YQRMKKAIDIVTGLFMIAFGLRLLIGLLPAGLTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]