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The map label for this gene is soxB [H]

Identifier: 66045873

GI number: 66045873

Start: 3203776

End: 3205101

Strand: Direct

Name: soxB [H]

Synonym: Psyr_2637

Alternate gene names: 66045873

Gene position: 3203776-3205101 (Clockwise)

Preceding gene: 66045871

Following gene: 66045875

Centisome position: 52.58

GC content: 63.42

Gene sequence:

>1326_bases
ATGCCAGCACCTTTAACTCCCGTGCATACCTCTGCAGATCTGCCGGCGCAGGCCGATGTGGTTGTGATCGGCGGCGGTAT
CATCGGCGCGTTTACCGCCTATTACCTTGCCAGGCGCGGCATGAAGGTCGCGCTGGTTGAAAAGGGCCGCATAGGCGCCG
AGCAGTCAAGCCGTAACTGGGGCTGGTGCCGCCAACAGAATCGCGATGCGCGTGAACTGCCGATGGCCACCAAAAGCCTG
GAACTGTGGGAGCAATTCGCCGAGCAATCCGGTGAACAGACCGGCTTTACACGTTGCGGCTTGCTCTACCTGAGTAACAA
CGACCAGGAGCTGGAAGGGTGGGCGCGCTGGGGCGAGTTTGCGCGCACTGTCAACGTGCAGACCCAGATGCTCACCGCCG
AGCAGGCCGCCGAACGGGGCAGGGCGACGGGCAAGCCTTGGAAAGGCGGGGTGTTTGCGCCCACCGATGGCATTGCCGAC
CCTTCCCGCGCAGCCCCCGCAGTCGCGCGCGCCATCATGGCACTGGGCAGTAGCGTGCATCAGGATTGCGCCGTGCGAGG
CGTCGAGACCGAAGGTGGTCGCTTGTCGGCAGTGGTCACCGAAAAAGGCACCATCCGCACCCGGCTCGCGGTGCTTGCCG
CAGGCGCCTGGGCATCTTCGTTCTGCCGCCAGTATGGTATTCGCTTCCCGCAAGCGACGATTCGTCAGACCGTACTTTCG
GTCACCGCCCCGAGCCAGGAAATTCCCAGTGCGCTGCATACCACCGGCGCGTCCATGACCCGCCGCTTTGATGGCAGTTA
CACGCTGGCGATCAGTGGCCGGGGGCGAGTCGATATCACGCCGCAGTTGCTGAGGTTCTCTACACAATTCCTGCCAATGT
TTCAGCGCCGCTGGCGCAACCTTGCGCCTGGGGGGCTGGAAGGCTGGCAAGCAGGCCACGAAAGCTTGAAGCGCTGGCGC
CTGGACCAGCCCACGCCGATGGAGAGAATGCGCATTCTCGACCCAAGCGCTGACGCCTCCGCGGTTGCGCTGACTTACAA
ACGCGCGGTGGAATTGGTGCCGGCACTGCAGGGTACGTCGATCAAGGCGTCGTGGGCCGGTTACGTGGACAGTACGCCGG
ACGGCGTTCCCGGTATTGGCGAAATGGCCAGCCTGCCGGGGTTGGTGATCGCGGCCGGGTTCAGCGGGCATGGCTTTGGT
ATTGGCCCGGGCGCGGGTCATCTTATTGCCGATATTGTCAGCGGTGTGAGCCCCATTGTTGATCCGCGTCCTTATCATCC
GGACCGCTTTCAAACGTCCGCCTGGGGCAAGGTGGCGGACTTTTGA

Upstream 100 bases:

>100_bases
GCCCGGTACACACCACAGTGGTTGGCGCCGTATCGGTGGGCAGGCCGGATCGGGCTCTAGCAACACGTCACTCTTCTGAA
CTCAGGTGGATAACCAGAAC

Downstream 100 bases:

>100_bases
GCTGAAGCCGTCTTGTTGAAAACGTTTGGCCGGGTGAGCGGGTGGGTTTATTTCGCCTTTTCAGTCTCGCGCATGAACTG
CCCGAGTTCCTTGCTATAGA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPAPLTPVHTSADLPAQADVVVIGGGIIGAFTAYYLARRGMKVALVEKGRIGAEQSSRNWGWCRQQNRDARELPMATKSL
ELWEQFAEQSGEQTGFTRCGLLYLSNNDQELEGWARWGEFARTVNVQTQMLTAEQAAERGRATGKPWKGGVFAPTDGIAD
PSRAAPAVARAIMALGSSVHQDCAVRGVETEGGRLSAVVTEKGTIRTRLAVLAAGAWASSFCRQYGIRFPQATIRQTVLS
VTAPSQEIPSALHTTGASMTRRFDGSYTLAISGRGRVDITPQLLRFSTQFLPMFQRRWRNLAPGGLEGWQAGHESLKRWR
LDQPTPMERMRILDPSADASAVALTYKRAVELVPALQGTSIKASWAGYVDSTPDGVPGIGEMASLPGLVIAAGFSGHGFG
IGPGAGHLIADIVSGVSPIVDPRPYHPDRFQTSAWGKVADF

Sequences:

>Translated_441_residues
MPAPLTPVHTSADLPAQADVVVIGGGIIGAFTAYYLARRGMKVALVEKGRIGAEQSSRNWGWCRQQNRDARELPMATKSL
ELWEQFAEQSGEQTGFTRCGLLYLSNNDQELEGWARWGEFARTVNVQTQMLTAEQAAERGRATGKPWKGGVFAPTDGIAD
PSRAAPAVARAIMALGSSVHQDCAVRGVETEGGRLSAVVTEKGTIRTRLAVLAAGAWASSFCRQYGIRFPQATIRQTVLS
VTAPSQEIPSALHTTGASMTRRFDGSYTLAISGRGRVDITPQLLRFSTQFLPMFQRRWRNLAPGGLEGWQAGHESLKRWR
LDQPTPMERMRILDPSADASAVALTYKRAVELVPALQGTSIKASWAGYVDSTPDGVPGIGEMASLPGLVIAAGFSGHGFG
IGPGAGHLIADIVSGVSPIVDPRPYHPDRFQTSAWGKVADF
>Mature_440_residues
PAPLTPVHTSADLPAQADVVVIGGGIIGAFTAYYLARRGMKVALVEKGRIGAEQSSRNWGWCRQQNRDARELPMATKSLE
LWEQFAEQSGEQTGFTRCGLLYLSNNDQELEGWARWGEFARTVNVQTQMLTAEQAAERGRATGKPWKGGVFAPTDGIADP
SRAAPAVARAIMALGSSVHQDCAVRGVETEGGRLSAVVTEKGTIRTRLAVLAAGAWASSFCRQYGIRFPQATIRQTVLSV
TAPSQEIPSALHTTGASMTRRFDGSYTLAISGRGRVDITPQLLRFSTQFLPMFQRRWRNLAPGGLEGWQAGHESLKRWRL
DQPTPMERMRILDPSADASAVALTYKRAVELVPALQGTSIKASWAGYVDSTPDGVPGIGEMASLPGLVIAAGFSGHGFGI
GPGAGHLIADIVSGVSPIVDPRPYHPDRFQTSAWGKVADF

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=435, Percent_Identity=26.4367816091954, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI21361378, Length=435, Percent_Identity=26.4367816091954, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI194306651, Length=411, Percent_Identity=23.3576642335766, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI24797151, Length=435, Percent_Identity=23.448275862069, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI20130091, Length=405, Percent_Identity=24.4444444444444, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571104, Length=208, Percent_Identity=29.8076923076923, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 47456; Mature: 47325

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPLTPVHTSADLPAQADVVVIGGGIIGAFTAYYLARRGMKVALVEKGRIGAEQSSRNW
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GWCRQQNRDARELPMATKSLELWEQFAEQSGEQTGFTRCGLLYLSNNDQELEGWARWGEF
CHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
ARTVNVQTQMLTAEQAAERGRATGKPWKGGVFAPTDGIADPSRAAPAVARAIMALGSSVH
HHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QDCAVRGVETEGGRLSAVVTEKGTIRTRLAVLAAGAWASSFCRQYGIRFPQATIRQTVLS
HHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VTAPSQEIPSALHTTGASMTRRFDGSYTLAISGRGRVDITPQLLRFSTQFLPMFQRRWRN
HCCCHHHHHHHHHHCCHHHHEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LAPGGLEGWQAGHESLKRWRLDQPTPMERMRILDPSADASAVALTYKRAVELVPALQGTS
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
IKASWAGYVDSTPDGVPGIGEMASLPGLVIAAGFSGHGFGIGPGAGHLIADIVSGVSPIV
EEEEECCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
DPRPYHPDRFQTSAWGKVADF
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PAPLTPVHTSADLPAQADVVVIGGGIIGAFTAYYLARRGMKVALVEKGRIGAEQSSRNW
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GWCRQQNRDARELPMATKSLELWEQFAEQSGEQTGFTRCGLLYLSNNDQELEGWARWGEF
CHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
ARTVNVQTQMLTAEQAAERGRATGKPWKGGVFAPTDGIADPSRAAPAVARAIMALGSSVH
HHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QDCAVRGVETEGGRLSAVVTEKGTIRTRLAVLAAGAWASSFCRQYGIRFPQATIRQTVLS
HHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VTAPSQEIPSALHTTGASMTRRFDGSYTLAISGRGRVDITPQLLRFSTQFLPMFQRRWRN
HCCCHHHHHHHHHHCCHHHHEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LAPGGLEGWQAGHESLKRWRLDQPTPMERMRILDPSADASAVALTYKRAVELVPALQGTS
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
IKASWAGYVDSTPDGVPGIGEMASLPGLVIAAGFSGHGFGIGPGAGHLIADIVSGVSPIV
EEEEECCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
DPRPYHPDRFQTSAWGKVADF
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]