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The map label for this gene is bdlA [H]

Identifier: 66045832

GI number: 66045832

Start: 3042083

End: 3043444

Strand: Direct

Name: bdlA [H]

Synonym: Psyr_2596

Alternate gene names: 66045832

Gene position: 3042083-3043444 (Clockwise)

Preceding gene: 66045831

Following gene: 66045833

Centisome position: 49.92

GC content: 56.24

Gene sequence:

>1362_bases
ATGACCGATGCAGATTGCAAACCCAAACTGTCCCGGATAGCCGCAATGTTCAATTCGCATTTGAAAAACACCAATAAGGC
ATTGGAGCGCCGCCTCGCCATGCTTGAGCAAGCAGGGCAAATCCTCAATCTGGAGACAGTCGCCGTCGTGCTGGATGGCA
CGGGCAAAATACAGACCGTCAACGCGTTGTTCGAGACGGAGATGAGCTACGCACAGGCAGAGCTCGTCGGGCGCAGCCTG
TCTGAACTGAGCCCGCCGGAACTGAGCGGTGACGTTCACCAGAAGCGCGCATTGACCGCGATTCGCGACGGCAAGCATTT
CAGCGGCACGTTGCGCCTGGTCAGCAAGACCGGATCGAGGGTGTGGCTGAGAACCATCGTCGTACCCTATAAAAATGAAA
CCGGCGGCGTCGAGCAGATCACTCTGTATTCGAGTGTTCTGACGCGAACGATTGAAGCCTCGCGCGAGAACGAAGCCCTG
GTCAATGCGCTGCAACGTTCCACCGCTGTTATCGACTTCACCCTCGATGGCACGGTCATCAGCGCCAACGACAACTTTCT
GAGGGCGATGGGTTACGAGCTGAATCAGATAAAAGGCAAACATCATAAGATGTTTTGTGTGCCTGAAGAGTCCGCCTCTG
ATGCGTATACCCAATTCTGGGAAAGGCTGCGCCGGGGTGAGTTTATCGTCGATCGTTTCCGTCGAATTGACAAAGGCGGT
CGTGATGTATGGCTGGAGGCGTCTTACAACCCGATTACCGACGCCAACGGCAAACTCTATAAAATTGCCAAGTTCGCGAC
TGTGATCACTGAACAGGTCGAGCGCGAGAAAGCCGTCGCCGAAGCATCGGAAATGGCTTATCAAACCTCTATCGATACTG
ACAGCAGCGCACAGCAAGGCCGCAAAGTCATCAAGGACACGCTGCAGATGCTCGGCCAGCTGACCATTTCAATGGAAGAG
GCCACACGAGGCATCGAAGCACTGGACTCGCAAAGTCAGGTGATTGGAACAATCATCAAGACCATCAGCGGCATTGCCGA
ACAAACCAACCTGCTCGCGCTGAACGCAGCGATTGAAGCCGCCAGGGCCGGCGAACAGGGCAGGGGCTTCGCCGTAGTGG
CCGACGAGGTACGCCAACTGGCCTCTCGCACGACAAAAGCGGCGGAAGAGATCGTAAACGTCGTGAAGACCAACCAAAGC
CTGGCGTCCGACGCGGTAGGCGTGATTGTGCGCAGCACCGAACAGGCGTCCGAGGCACTGGTATTGGCCAATGACGCAGA
CCGTGTGATTCAGGAAATCCAGCACGGCGCGAACACGGTAGTGCGGGCAGTCAGCCGGTTTGTGGACCAGCGCTCCAGTT
AA

Upstream 100 bases:

>100_bases
TGATCAATAGTTATAACTTTTGGATCCTATAGTCACAATCAGACAACAGGCAGGCTATTTTCGTATTAAGTTCGATTGCA
CCGCTCAAGATTGCGGTTCC

Downstream 100 bases:

>100_bases
GTGCGAGCAGTCGGAGTGACTCAGGGGACGCTAAAAGTGTTCTGCGCTGAGTCACTCACCGCGCAGTCAAACAGGAAGGG
AAGTGTACTGATGGTCGCAG

Product: PAS

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTDADCKPKLSRIAAMFNSHLKNTNKALERRLAMLEQAGQILNLETVAVVLDGTGKIQTVNALFETEMSYAQAELVGRSL
SELSPPELSGDVHQKRALTAIRDGKHFSGTLRLVSKTGSRVWLRTIVVPYKNETGGVEQITLYSSVLTRTIEASRENEAL
VNALQRSTAVIDFTLDGTVISANDNFLRAMGYELNQIKGKHHKMFCVPEESASDAYTQFWERLRRGEFIVDRFRRIDKGG
RDVWLEASYNPITDANGKLYKIAKFATVITEQVEREKAVAEASEMAYQTSIDTDSSAQQGRKVIKDTLQMLGQLTISMEE
ATRGIEALDSQSQVIGTIIKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTTKAAEEIVNVVKTNQS
LASDAVGVIVRSTEQASEALVLANDADRVIQEIQHGANTVVRAVSRFVDQRSS

Sequences:

>Translated_453_residues
MTDADCKPKLSRIAAMFNSHLKNTNKALERRLAMLEQAGQILNLETVAVVLDGTGKIQTVNALFETEMSYAQAELVGRSL
SELSPPELSGDVHQKRALTAIRDGKHFSGTLRLVSKTGSRVWLRTIVVPYKNETGGVEQITLYSSVLTRTIEASRENEAL
VNALQRSTAVIDFTLDGTVISANDNFLRAMGYELNQIKGKHHKMFCVPEESASDAYTQFWERLRRGEFIVDRFRRIDKGG
RDVWLEASYNPITDANGKLYKIAKFATVITEQVEREKAVAEASEMAYQTSIDTDSSAQQGRKVIKDTLQMLGQLTISMEE
ATRGIEALDSQSQVIGTIIKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTTKAAEEIVNVVKTNQS
LASDAVGVIVRSTEQASEALVLANDADRVIQEIQHGANTVVRAVSRFVDQRSS
>Mature_452_residues
TDADCKPKLSRIAAMFNSHLKNTNKALERRLAMLEQAGQILNLETVAVVLDGTGKIQTVNALFETEMSYAQAELVGRSLS
ELSPPELSGDVHQKRALTAIRDGKHFSGTLRLVSKTGSRVWLRTIVVPYKNETGGVEQITLYSSVLTRTIEASRENEALV
NALQRSTAVIDFTLDGTVISANDNFLRAMGYELNQIKGKHHKMFCVPEESASDAYTQFWERLRRGEFIVDRFRRIDKGGR
DVWLEASYNPITDANGKLYKIAKFATVITEQVEREKAVAEASEMAYQTSIDTDSSAQQGRKVIKDTLQMLGQLTISMEEA
TRGIEALDSQSQVIGTIIKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTTKAAEEIVNVVKTNQSL
ASDAVGVIVRSTEQASEALVLANDADRVIQEIQHGANTVVRAVSRFVDQRSS

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=131, Percent_Identity=45.8015267175573, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788194, Length=136, Percent_Identity=44.8529411764706, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788195, Length=169, Percent_Identity=40.8284023668639, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789453, Length=75, Percent_Identity=57.3333333333333, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787690, Length=69, Percent_Identity=62.3188405797101, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 49723; Mature: 49592

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDADCKPKLSRIAAMFNSHLKNTNKALERRLAMLEQAGQILNLETVAVVLDGTGKIQTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEEEECCCCEEEH
NALFETEMSYAQAELVGRSLSELSPPELSGDVHQKRALTAIRDGKHFSGTLRLVSKTGSR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHEEHHCCCE
VWLRTIVVPYKNETGGVEQITLYSSVLTRTIEASRENEALVNALQRSTAVIDFTLDGTVI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCEEE
SANDNFLRAMGYELNQIKGKHHKMFCVPEESASDAYTQFWERLRRGEFIVDRFRRIDKGG
ECCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
RDVWLEASYNPITDANGKLYKIAKFATVITEQVEREKAVAEASEMAYQTSIDTDSSAQQG
CEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RKVIKDTLQMLGQLTISMEEATRGIEALDSQSQVIGTIIKTISGIAEQTNLLALNAAIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
ARAGEQGRGFAVVADEVRQLASRTTKAAEEIVNVVKTNQSLASDAVGVIVRSTEQASEAL
HHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCHHHCCEE
VLANDADRVIQEIQHGANTVVRAVSRFVDQRSS
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDADCKPKLSRIAAMFNSHLKNTNKALERRLAMLEQAGQILNLETVAVVLDGTGKIQTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEEEECCCCEEEH
NALFETEMSYAQAELVGRSLSELSPPELSGDVHQKRALTAIRDGKHFSGTLRLVSKTGSR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHEEHHCCCE
VWLRTIVVPYKNETGGVEQITLYSSVLTRTIEASRENEALVNALQRSTAVIDFTLDGTVI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCEEE
SANDNFLRAMGYELNQIKGKHHKMFCVPEESASDAYTQFWERLRRGEFIVDRFRRIDKGG
ECCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
RDVWLEASYNPITDANGKLYKIAKFATVITEQVEREKAVAEASEMAYQTSIDTDSSAQQG
CEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RKVIKDTLQMLGQLTISMEEATRGIEALDSQSQVIGTIIKTISGIAEQTNLLALNAAIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
ARAGEQGRGFAVVADEVRQLASRTTKAAEEIVNVVKTNQSLASDAVGVIVRSTEQASEAL
HHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCHHHCCEE
VLANDADRVIQEIQHGANTVVRAVSRFVDQRSS
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]