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The map label for this gene is yccK [H]

Identifier: 66045755

GI number: 66045755

Start: 2927785

End: 2928780

Strand: Reverse

Name: yccK [H]

Synonym: Psyr_2519

Alternate gene names: 66045755

Gene position: 2928780-2927785 (Counterclockwise)

Preceding gene: 66045761

Following gene: 66045753

Centisome position: 48.06

GC content: 61.35

Gene sequence:

>996_bases
GTGATCACGCGCCAATTGGGTCAACTCGGTCCGCACGTGTCCGCCCTCGGGCTGGGCTGCATGGGAATGTCGGACTTCTA
CACCACCGGCATCGACGAAAAGGAATCCATCGCCACCTTGCACCGCGCGATCGAGCTGGGTGTCAACTTTTTCGATACGG
CTGACATGTACGGCCCGCACACCAACGAAGCCTTGCTTGGTCGTGCCCTCGAGGGCAAGCGTGAAGGTATCTACCTGGCC
AGCAAGTTCGGCATCGTCCGTGGCGATGACCCGCATGCGCGTGGCGTCAATGGCAGTCCGGCGTACATTCGCCAGTCCAT
CGACGCCAGCCTGAAGCGGCTGAACACCGATTACCTTGATCTCTATTATCAGCACCGTGTCGACCCCACGGTGCCCATCG
AGGACACCATTGGCGCCATGGCCGAACTGGTCAAGGCTGGCAAGGTTCGCCACATAGGCATCTGCGAAGCCAGTGCCGCG
ACCATCGAAAAGGCCCACGCGGTGCATCCATTGGCGGCCGTGCAGAGCGAGTACTCACTCTGGTCACGCGATCCGGAACA
GGATGGCGTGCTTGTCACCTGCCGCCGTCTGGGCATTGCCTTCGTGGCGTACAGCCCGCTCGGCCGGGGGTTTCTGACCG
GTGAATTGCGCACCCCGGACGATTTCGCGGCCGATGACTACCGTCGCTTCACCCCACGGTTTCAGGGCGAAAACTTCAAT
CGCAATCTGCAATTGGTCGAGAAGGTCAAGGCACTGGCTACGGCCAGGGGCATCAGCGCGTCGCAACTGGCGCTGGCCTG
GGTGCTTGCCCAGGGAGATGACATCATTCCGATCCCCGGCACCAAGCAGCGCAAATACCTGGAAAGCAACGTGGCAGCGG
CTTCATTGACGCTGAGTACCGATGACCTTGCCCAGCTGGAGGCGATTTTCCCGGCCCAGGGGTCGGCATCCGGTGAGCGC
TATAACGCGGCGTCGATGAAGTCTCTCAACGGCTGA

Upstream 100 bases:

>100_bases
GTTTGGATTTCAACAACAGTGAAATAAGAAACACCCGGTTTATTGAGCCACGCAAAGAGGCGAAACTCGACCGATCTTTC
AACGATCAGGAGCACTCATT

Downstream 100 bases:

>100_bases
AAACCGTTGCGCTTGGGCATCAGGTCGCTTCAGGGCAGGTCTCGGCGCCGTTGTTGAGGCCCTGCTTTTGATTCTTGTAA
TCGAGCGTCGCTTTGCCATC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MITRQLGQLGPHVSALGLGCMGMSDFYTTGIDEKESIATLHRAIELGVNFFDTADMYGPHTNEALLGRALEGKREGIYLA
SKFGIVRGDDPHARGVNGSPAYIRQSIDASLKRLNTDYLDLYYQHRVDPTVPIEDTIGAMAELVKAGKVRHIGICEASAA
TIEKAHAVHPLAAVQSEYSLWSRDPEQDGVLVTCRRLGIAFVAYSPLGRGFLTGELRTPDDFAADDYRRFTPRFQGENFN
RNLQLVEKVKALATARGISASQLALAWVLAQGDDIIPIPGTKQRKYLESNVAAASLTLSTDDLAQLEAIFPAQGSASGER
YNAASMKSLNG

Sequences:

>Translated_331_residues
MITRQLGQLGPHVSALGLGCMGMSDFYTTGIDEKESIATLHRAIELGVNFFDTADMYGPHTNEALLGRALEGKREGIYLA
SKFGIVRGDDPHARGVNGSPAYIRQSIDASLKRLNTDYLDLYYQHRVDPTVPIEDTIGAMAELVKAGKVRHIGICEASAA
TIEKAHAVHPLAAVQSEYSLWSRDPEQDGVLVTCRRLGIAFVAYSPLGRGFLTGELRTPDDFAADDYRRFTPRFQGENFN
RNLQLVEKVKALATARGISASQLALAWVLAQGDDIIPIPGTKQRKYLESNVAAASLTLSTDDLAQLEAIFPAQGSASGER
YNAASMKSLNG
>Mature_331_residues
MITRQLGQLGPHVSALGLGCMGMSDFYTTGIDEKESIATLHRAIELGVNFFDTADMYGPHTNEALLGRALEGKREGIYLA
SKFGIVRGDDPHARGVNGSPAYIRQSIDASLKRLNTDYLDLYYQHRVDPTVPIEDTIGAMAELVKAGKVRHIGICEASAA
TIEKAHAVHPLAAVQSEYSLWSRDPEQDGVLVTCRRLGIAFVAYSPLGRGFLTGELRTPDDFAADDYRRFTPRFQGENFN
RNLQLVEKVKALATARGISASQLALAWVLAQGDDIIPIPGTKQRKYLESNVAAASLTLSTDDLAQLEAIFPAQGSASGER
YNAASMKSLNG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=27.6073619631902, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=27.2445820433437, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI27436971, Length=281, Percent_Identity=28.8256227758007, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436962, Length=284, Percent_Identity=27.8169014084507, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436964, Length=284, Percent_Identity=27.8169014084507, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436966, Length=284, Percent_Identity=27.8169014084507, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI223718702, Length=319, Percent_Identity=30.4075235109718, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI41152114, Length=327, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41327764, Length=228, Percent_Identity=31.140350877193, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=34.0625, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=31.5950920245399, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788070, Length=311, Percent_Identity=32.7974276527331, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788081, Length=282, Percent_Identity=31.5602836879433, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=31.7784256559767, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI48994888, Length=302, Percent_Identity=28.476821192053, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI212645785, Length=161, Percent_Identity=29.8136645962733, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6325384, Length=345, Percent_Identity=26.0869565217391, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=26.8221574344023, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=25.2307692307692, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=24.1610738255034, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=320, Percent_Identity=24.375, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.7011952191235, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=160, Percent_Identity=37.5, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=35.2201257861635, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=341, Percent_Identity=24.633431085044, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=24.188790560472, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35929; Mature: 35929

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRQLGQLGPHVSALGLGCMGMSDFYTTGIDEKESIATLHRAIELGVNFFDTADMYGPH
CCCCHHHHCCCCHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
TNEALLGRALEGKREGIYLASKFGIVRGDDPHARGVNGSPAYIRQSIDASLKRLNTDYLD
CCHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LYYQHRVDPTVPIEDTIGAMAELVKAGKVRHIGICEASAATIEKAHAVHPLAAVQSEYSL
HHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WSRDPEQDGVLVTCRRLGIAFVAYSPLGRGFLTGELRTPDDFAADDYRRFTPRFQGENFN
HCCCCCCCCEEEEEHHHCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
RNLQLVEKVKALATARGISASQLALAWVLAQGDDIIPIPGTKQRKYLESNVAAASLTLST
CCHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCHHHHHHHCCCEEEEEECC
DDLAQLEAIFPAQGSASGERYNAASMKSLNG
HHHHHHHHHCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MITRQLGQLGPHVSALGLGCMGMSDFYTTGIDEKESIATLHRAIELGVNFFDTADMYGPH
CCCCHHHHCCCCHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
TNEALLGRALEGKREGIYLASKFGIVRGDDPHARGVNGSPAYIRQSIDASLKRLNTDYLD
CCHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LYYQHRVDPTVPIEDTIGAMAELVKAGKVRHIGICEASAATIEKAHAVHPLAAVQSEYSL
HHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WSRDPEQDGVLVTCRRLGIAFVAYSPLGRGFLTGELRTPDDFAADDYRRFTPRFQGENFN
HCCCCCCCCEEEEEHHHCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
RNLQLVEKVKALATARGISASQLALAWVLAQGDDIIPIPGTKQRKYLESNVAAASLTLST
CCHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCHHHHHHHCCCEEEEEECC
DDLAQLEAIFPAQGSASGERYNAASMKSLNG
HHHHHHHHHCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]