Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 66045718

GI number: 66045718

Start: 2879475

End: 2880779

Strand: Direct

Name: mdtA [H]

Synonym: Psyr_2482

Alternate gene names: 66045718

Gene position: 2879475-2880779 (Clockwise)

Preceding gene: 66045717

Following gene: 66045719

Centisome position: 47.25

GC content: 60.08

Gene sequence:

>1305_bases
ATGGTTGATTTATTCATGCAATCGTCTGGCTCCCGTAAATCCCGTCGCTGGTTGATCAGTTTGCTGGTCCTGTTGGTCAT
CGTCGCCTTGTGCTGGTGGTTCTGGCCTGCGTCCACTTCCGGCAAGGGGGCCGAGAGCAACAAGAAGCCCGCTACAAGCG
GCATGGCAAGGCCCGGCTTCGGCGGATCGGCTGTGGCGGTCCCGGTGCGTGTGGCCCCGGCTACCGAAGGTGATTTTCCG
ATCTACTACAAGGCACTTGGCACCGTGACGGCGATGAACACCATCAATGTGCGCAGCCGCGTGGCGGGGGAGCTGGTCAA
GCTTTATTTCCAGGAAGGGCAGATGGTCAAGGCGGGTGATCTGCTGGCTGAAATCGATCCGCGCAGCTATCAAGTGGCGT
TGCAGCAGGCCGAAGGTACGCTGGCCACCAACCAGGCGCTGCTCAAGAACGCTCAGCTCGACGTGCAGCGTTACCGAGGC
TTGTTTGCCGAGGACAGCATCGCCAAGCAGACCCTCGACACTGCCGAGTCGCTGGTCAACCAATACAAGGGCACGATCAA
GACCAATCAGGCTGCCGTGGCTGACGCAAAACTCAACCTGGACTTCAGTCGCATTCGTGCCCCGATTGCCGGGCGTGTCG
GCCTCAAACAGCTGGACGTGGGTAATCTGGTTGCCGCCAATGACACCACGGCACTGGCGGTGATTACCCAGACCCAGCCT
ATTTCCGTCGCATTCACGCTGCCTGAAAAGGACCTGTCGAAAGTTATTTCCCGCTACCGCACCGGCGACAAGCTGCCGGT
CGAAGCCTGGGACCGTGGCGATACGAAGATGCAGGCCACCGGCGTACTGGCCAGCCTCGACAACCAGATCGACGTGGCTA
CCGGCACACTGAAGTTCAAGGCGCGTTTCGATAACAGCGACGAGGTCCTGTTTCCCAATCAGTTCGTCAATATACGGCTG
CGCGCCGACACGCTGAAAAAAGTCACGCTGGTGCCGACGGCTGCCGTGCAGTTTGGCACCGACGGGACCTTTGTCTACGT
GCTGGACGGTGACAAGAAGGTCAAGCTCAAACTGCTGAAGACCGGCCCGAGCGACGAGACATCCACGGTGATTACCGAAG
GTCTGGCAGCCGGCGAGCGGGTGGTGCTCGAAGGCACCGACCGTCTGCGCGACGGTGCCGAAGTCGAAGTCGTCAACGAC
AGCAAGGAAGTCCCGGCTGGCCCGGCTCAGAAGCTGCAAGGCAAGCCTGACAGCAAGACCGACAAGTCGGCGGCGCTCGG
CAAGGTGGAAAAACCAAACGTATGA

Upstream 100 bases:

>100_bases
TGCTTCATACGTTTATCCAAAGTAAGCGCTTGGTAAAGGCGCTTTGCTTGTAACGTAACTGTGCTTATTGTTCAGCCTTC
TGAACAAACCCCCACCTGTA

Downstream 100 bases:

>100_bases
ACATGTCGCGCCTGTTCATCCTGCGTCCGGTTGCCACCACACTGAGCATGTTGGCAATCGTCCTGGCGGGTCTGATCGCC
TATACCTTGCTACCGGTTTC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MVDLFMQSSGSRKSRRWLISLLVLLVIVALCWWFWPASTSGKGAESNKKPATSGMARPGFGGSAVAVPVRVAPATEGDFP
IYYKALGTVTAMNTINVRSRVAGELVKLYFQEGQMVKAGDLLAEIDPRSYQVALQQAEGTLATNQALLKNAQLDVQRYRG
LFAEDSIAKQTLDTAESLVNQYKGTIKTNQAAVADAKLNLDFSRIRAPIAGRVGLKQLDVGNLVAANDTTALAVITQTQP
ISVAFTLPEKDLSKVISRYRTGDKLPVEAWDRGDTKMQATGVLASLDNQIDVATGTLKFKARFDNSDEVLFPNQFVNIRL
RADTLKKVTLVPTAAVQFGTDGTFVYVLDGDKKVKLKLLKTGPSDETSTVITEGLAAGERVVLEGTDRLRDGAEVEVVND
SKEVPAGPAQKLQGKPDSKTDKSAALGKVEKPNV

Sequences:

>Translated_434_residues
MVDLFMQSSGSRKSRRWLISLLVLLVIVALCWWFWPASTSGKGAESNKKPATSGMARPGFGGSAVAVPVRVAPATEGDFP
IYYKALGTVTAMNTINVRSRVAGELVKLYFQEGQMVKAGDLLAEIDPRSYQVALQQAEGTLATNQALLKNAQLDVQRYRG
LFAEDSIAKQTLDTAESLVNQYKGTIKTNQAAVADAKLNLDFSRIRAPIAGRVGLKQLDVGNLVAANDTTALAVITQTQP
ISVAFTLPEKDLSKVISRYRTGDKLPVEAWDRGDTKMQATGVLASLDNQIDVATGTLKFKARFDNSDEVLFPNQFVNIRL
RADTLKKVTLVPTAAVQFGTDGTFVYVLDGDKKVKLKLLKTGPSDETSTVITEGLAAGERVVLEGTDRLRDGAEVEVVND
SKEVPAGPAQKLQGKPDSKTDKSAALGKVEKPNV
>Mature_434_residues
MVDLFMQSSGSRKSRRWLISLLVLLVIVALCWWFWPASTSGKGAESNKKPATSGMARPGFGGSAVAVPVRVAPATEGDFP
IYYKALGTVTAMNTINVRSRVAGELVKLYFQEGQMVKAGDLLAEIDPRSYQVALQQAEGTLATNQALLKNAQLDVQRYRG
LFAEDSIAKQTLDTAESLVNQYKGTIKTNQAAVADAKLNLDFSRIRAPIAGRVGLKQLDVGNLVAANDTTALAVITQTQP
ISVAFTLPEKDLSKVISRYRTGDKLPVEAWDRGDTKMQATGVLASLDNQIDVATGTLKFKARFDNSDEVLFPNQFVNIRL
RADTLKKVTLVPTAAVQFGTDGTFVYVLDGDKKVKLKLLKTGPSDETSTVITEGLAAGERVVLEGTDRLRDGAEVEVVND
SKEVPAGPAQKLQGKPDSKTDKSAALGKVEKPNV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=371, Percent_Identity=50.1347708894879, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786668, Length=339, Percent_Identity=33.0383480825959, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1789929, Length=314, Percent_Identity=29.2993630573248, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789665, Length=332, Percent_Identity=29.2168674698795, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081796, Length=336, Percent_Identity=27.9761904761905, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081951, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46787; Mature: 46787

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLFMQSSGSRKSRRWLISLLVLLVIVALCWWFWPASTSGKGAESNKKPATSGMARPGF
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GGSAVAVPVRVAPATEGDFPIYYKALGTVTAMNTINVRSRVAGELVKLYFQEGQMVKAGD
CCCEEEEEEEEECCCCCCCCEEEEEHHHHHEEEEHHHHHHHHHHHHHHHHHCCCEEECCC
LLAEIDPRSYQVALQQAEGTLATNQALLKNAQLDVQRYRGLFAEDSIAKQTLDTAESLVN
EEEECCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QYKGTIKTNQAAVADAKLNLDFSRIRAPIAGRVGLKQLDVGNLVAANDTTALAVITQTQP
HHCCCEECCCEEEEEEEECCCHHHHCCCCCCCCCCEEECCCCEEEECCCEEEEEEEECCC
ISVAFTLPEKDLSKVISRYRTGDKLPVEAWDRGDTKMQATGVLASLDNQIDVATGTLKFK
EEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEEEEEEEEE
ARFDNSDEVLFPNQFVNIRLRADTLKKVTLVPTAAVQFGTDGTFVYVLDGDKKVKLKLLK
EEECCCCCEECCCCEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEEEECCCEEEEEEEE
TGPSDETSTVITEGLAAGERVVLEGTDRLRDGAEVEVVNDSKEVPAGPAQKLQGKPDSKT
CCCCCCHHHHHHHHHCCCCEEEEECCHHCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCC
DKSAALGKVEKPNV
CCHHHCCCCCCCCC
>Mature Secondary Structure
MVDLFMQSSGSRKSRRWLISLLVLLVIVALCWWFWPASTSGKGAESNKKPATSGMARPGF
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GGSAVAVPVRVAPATEGDFPIYYKALGTVTAMNTINVRSRVAGELVKLYFQEGQMVKAGD
CCCEEEEEEEEECCCCCCCCEEEEEHHHHHEEEEHHHHHHHHHHHHHHHHHCCCEEECCC
LLAEIDPRSYQVALQQAEGTLATNQALLKNAQLDVQRYRGLFAEDSIAKQTLDTAESLVN
EEEECCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QYKGTIKTNQAAVADAKLNLDFSRIRAPIAGRVGLKQLDVGNLVAANDTTALAVITQTQP
HHCCCEECCCEEEEEEEECCCHHHHCCCCCCCCCCEEECCCCEEEECCCEEEEEEEECCC
ISVAFTLPEKDLSKVISRYRTGDKLPVEAWDRGDTKMQATGVLASLDNQIDVATGTLKFK
EEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEEEEEEEEE
ARFDNSDEVLFPNQFVNIRLRADTLKKVTLVPTAAVQFGTDGTFVYVLDGDKKVKLKLLK
EEECCCCCEECCCCEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEEEECCCEEEEEEEE
TGPSDETSTVITEGLAAGERVVLEGTDRLRDGAEVEVVNDSKEVPAGPAQKLQGKPDSKT
CCCCCCHHHHHHHHHCCCCEEEEECCHHCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCC
DKSAALGKVEKPNV
CCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA