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The map label for this gene is caiD [C]

Identifier: 66045688

GI number: 66045688

Start: 2840775

End: 2841587

Strand: Direct

Name: caiD [C]

Synonym: Psyr_2452

Alternate gene names: 66045688

Gene position: 2840775-2841587 (Clockwise)

Preceding gene: 66045685

Following gene: 66045689

Centisome position: 46.62

GC content: 59.29

Gene sequence:

>813_bases
GTGACCGATTATCAAAGTTTCCGGGTCGATCTGGCCGACAGCATTGCTCACGTACAAATCAACCGGCCCGAAAAACTCAA
CGCAATGAACGAGTCGTTCTGGACGGAGATAATCGCCATTTTCGACTGGATAGAGCGTACCGACGAGGTGCGCGTCGTGG
TGCTCAGCGGTGCGGGCAAGCACTTTTCGTCAGGCATCGATCTGGCACTGCTGGCCTCGGTCGCCAGCCAGATGGGCAAG
GATGCCGGGCGTAACGCCCGCCTGTTGCGGCGCAAGATCCGTGACATGCAGGCTTCGTTCACTGCCGTGGACAATTGCCG
AAAACCGGTTCTCGCCGCCATCCAGGGCTATTGCCTGGGCGGCGCCATCGACCTGATTTCCGCGTGTGACATGCGTTACG
CGGCGGCCGACGCGCAGTTCGCCATTCGCGAGATCGACATGGGTATGGCCGCTGATGTCGGCACGCTGCAACGGCTGCCA
AGGATCATCGGTGATGGTGTGTTGCGCGAACTGGCCTACACCGGGCGTACCGTCGGCGCTGAAGAGGCGCAACGCATCGG
GCTGGTCAATCGCACCTTCGATGACGCGGACGGTCTGTTGCAGGGTGTCCTGGCGGTGGCTCGGGAAATAGCCGGAAAGT
CGCCCATCGCCATCGAAGGCACCAAGCAAATGATCAGCTACATGCGTGATCACAGAGTGGAAGATGGTCTCGAACACGTT
GCCATCTGGAACGCAGCCATGCTGCAATCACCTGACCTGAAGCTGGCGATGGCTGCGCAGATGAGCAAGCACAAGCCAGT
CTTTGATAATTGA

Upstream 100 bases:

>100_bases
TTTCGCGTCCGGCAAATGTCACTTCAGTCCGGTTCCGGTGTGCCTGTTGCAGTTGTTATAGTCCTGCGCCTGAACACCCA
ACCTGCCTGAGGATCACGTC

Downstream 100 bases:

>100_bases
TACATGACAAGGCTCGAGTTTGAGCGAAGGAGTTTCTAATGTCGCGCCCGGAGCGTTGGACAACTGCAGTTCTGGATGTC
GAGGCCCCTGGCGGTTTGGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTDYQSFRVDLADSIAHVQINRPEKLNAMNESFWTEIIAIFDWIERTDEVRVVVLSGAGKHFSSGIDLALLASVASQMGK
DAGRNARLLRRKIRDMQASFTAVDNCRKPVLAAIQGYCLGGAIDLISACDMRYAAADAQFAIREIDMGMAADVGTLQRLP
RIIGDGVLRELAYTGRTVGAEEAQRIGLVNRTFDDADGLLQGVLAVAREIAGKSPIAIEGTKQMISYMRDHRVEDGLEHV
AIWNAAMLQSPDLKLAMAAQMSKHKPVFDN

Sequences:

>Translated_270_residues
MTDYQSFRVDLADSIAHVQINRPEKLNAMNESFWTEIIAIFDWIERTDEVRVVVLSGAGKHFSSGIDLALLASVASQMGK
DAGRNARLLRRKIRDMQASFTAVDNCRKPVLAAIQGYCLGGAIDLISACDMRYAAADAQFAIREIDMGMAADVGTLQRLP
RIIGDGVLRELAYTGRTVGAEEAQRIGLVNRTFDDADGLLQGVLAVAREIAGKSPIAIEGTKQMISYMRDHRVEDGLEHV
AIWNAAMLQSPDLKLAMAAQMSKHKPVFDN
>Mature_269_residues
TDYQSFRVDLADSIAHVQINRPEKLNAMNESFWTEIIAIFDWIERTDEVRVVVLSGAGKHFSSGIDLALLASVASQMGKD
AGRNARLLRRKIRDMQASFTAVDNCRKPVLAAIQGYCLGGAIDLISACDMRYAAADAQFAIREIDMGMAADVGTLQRLPR
IIGDGVLRELAYTGRTVGAEEAQRIGLVNRTFDDADGLLQGVLAVAREIAGKSPIAIEGTKQMISYMRDHRVEDGLEHVA
IWNAAMLQSPDLKLAMAAQMSKHKPVFDN

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=253, Percent_Identity=48.6166007905138, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI194097323, Length=258, Percent_Identity=27.1317829457364, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI20127408, Length=186, Percent_Identity=27.9569892473118, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI45643119, Length=224, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260275230, Length=224, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260274832, Length=224, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221136756, Length=249, Percent_Identity=22.8915662650602, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221136753, Length=249, Percent_Identity=22.8915662650602, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221307494, Length=249, Percent_Identity=22.8915662650602, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI116235487, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI68989263, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4502327, Length=216, Percent_Identity=28.2407407407407, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542718, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI221142681, Length=237, Percent_Identity=31.2236286919831, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=26.5873015873016, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082183, Length=269, Percent_Identity=25.6505576208178, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788682, Length=194, Percent_Identity=30.9278350515464, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=25.5813953488372, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788597, Length=239, Percent_Identity=30.1255230125523, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790281, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=273, Percent_Identity=41.3919413919414, Blast_Score=234, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=40.9961685823755, Blast_Score=219, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17554946, Length=263, Percent_Identity=26.9961977186312, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=259, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17540714, Length=215, Percent_Identity=30.2325581395349, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=201, Percent_Identity=27.8606965174129, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508953, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25141363, Length=236, Percent_Identity=25.8474576271186, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=195, Percent_Identity=24.1025641025641, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=44.1860465116279, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI20129971, Length=276, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24653477, Length=276, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=26.4591439688716, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357171, Length=190, Percent_Identity=31.0526315789474, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654903, Length=194, Percent_Identity=24.7422680412371, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650670, Length=266, Percent_Identity=27.4436090225564, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921000, Length=201, Percent_Identity=25.8706467661692, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583077, Length=201, Percent_Identity=25.8706467661692, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24583079, Length=201, Percent_Identity=25.8706467661692, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29608; Mature: 29477

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYQSFRVDLADSIAHVQINRPEKLNAMNESFWTEIIAIFDWIERTDEVRVVVLSGAGK
CCCHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
HFSSGIDLALLASVASQMGKDAGRNARLLRRKIRDMQASFTAVDNCRKPVLAAIQGYCLG
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIDLISACDMRYAAADAQFAIREIDMGMAADVGTLQRLPRIIGDGVLRELAYTGRTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEAQRIGLVNRTFDDADGLLQGVLAVAREIAGKSPIAIEGTKQMISYMRDHRVEDGLEHV
HHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
AIWNAAMLQSPDLKLAMAAQMSKHKPVFDN
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDYQSFRVDLADSIAHVQINRPEKLNAMNESFWTEIIAIFDWIERTDEVRVVVLSGAGK
CCHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
HFSSGIDLALLASVASQMGKDAGRNARLLRRKIRDMQASFTAVDNCRKPVLAAIQGYCLG
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIDLISACDMRYAAADAQFAIREIDMGMAADVGTLQRLPRIIGDGVLRELAYTGRTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEAQRIGLVNRTFDDADGLLQGVLAVAREIAGKSPIAIEGTKQMISYMRDHRVEDGLEHV
HHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
AIWNAAMLQSPDLKLAMAAQMSKHKPVFDN
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA