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The map label for this gene is torS [H]

Identifier: 66045684

GI number: 66045684

Start: 2835328

End: 2836509

Strand: Direct

Name: torS [H]

Synonym: Psyr_2448

Alternate gene names: 66045684

Gene position: 2835328-2836509 (Clockwise)

Preceding gene: 66045683

Following gene: 66045685

Centisome position: 46.53

GC content: 57.53

Gene sequence:

>1182_bases
ATGTTAAGTGAAATTCAGGCAAAACTGCTCATCGTTGACGATTTGCCGGAAAACCTGCTGGCGCTCGAAGCGCTGATCAA
GCGCGGTGATCGAATCGTCTACAAGGCGCTGTCTGCGGACGAAGCGCTGTCACTGTTGCTGCAGCACGAATTCGCCATGG
CCATCCTCGACGTTCAGATGCCCGGAATGAACGGCTTCGAACTGGCCGAGCTGATGCGCAGCACGGAAAAGACCAAAAGC
ATTCCAATTGTCTTCGTCAGTGCTGCCGGCCGCGAGCTGAATTACGCCTTCAAGGGCTATGAAAGCGGTGCCGTGGATTT
TCTGCACAAGCCGCTGGATATTCACGCGGTGAAGAGCAAGGTCAACGTGTTCGTCGATCTTTACCGACAGCGCAAGGCCA
TGAAAATACAGGTCGAGGAGCTTGAGCGCAGTCGTCAGGAGCAGGAAGCCCTGCTCAAGCGTCTGCAGTCGACCCAGGGC
GAGCTGGAACACGCGATTCGCATGCGGGACGACTTCATGTCCATCGTGTCCCACGAGGTGCGCACGCCGCTCAACGGCCT
GATTCTGGAAACCCAGCTGCGCAAGCTGCACCTGGCCAAGGACAATGCGGCGGCGTTTACCATGGAGAAGCTGCGCGCGA
TGGTCGATCGCGACGAGCGACAGATTCAGAGCCTCATCCGCCTGATCGAAGACATGCTCGACGTATCAAGGATCCGTACT
GGCAAGCTGTCGATCAGACCGAGCCCGTTCGACCTGAGCGAACTGGTCACGCAACTGCTGGAGAGCTTTGCCGCGCAGAT
CGCCGCCGCCAATTCCACCATCACCCGGTTCGCCGAACAGCCGGTGATCGGTGTCTGGGACGAATTCCGTATCGAGCAGG
TGGTTGCCAACCTGCTGACCAACGCGCTGCGCTACGGTGCGCGAAAGCCGATTGAAGTGCATGTGTACAGCAAGGACAGC
GAGGCTTTCATCGAAGTCAGGGATCAAGGTATTGGCATTACGGCCGAAAACCAGAAGCGCATCTTTCAGCAGTTCGAGCG
GGTGTCGAGCAATCACGCGGTTGCCGGGTTGGGTCTTGGGTTGTTCATTTCCGATCAGATCGTCATGGCGCACGGCGGTC
GCATCGAGGTGGAAAGTGAAGAGGGCAAGGGTTCGGTGTTTCGTATCTGCCTGCCTCTGTAA

Upstream 100 bases:

>100_bases
CTTCTACCATGCCTGAAGCTGGCCTGGCGCTGCACTCGCCCGATTACCTCCTTTCCCTGAACGATATTGGCCGCTTGCTG
GTCGAGCTGGAACGAAGCGC

Downstream 100 bases:

>100_bases
GGTCGCCGCCACCGGCAATAAAGTTTAATCACAGGTTGGCGCAACCTCCCATGCGTGCCGTGGTCGTAATGGCAGCTATT
TATAAGATCAAAGGCAGTTC

Product: response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLSEIQAKLLIVDDLPENLLALEALIKRGDRIVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRSTEKTKS
IPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQRKAMKIQVEELERSRQEQEALLKRLQSTQG
ELEHAIRMRDDFMSIVSHEVRTPLNGLILETQLRKLHLAKDNAAAFTMEKLRAMVDRDERQIQSLIRLIEDMLDVSRIRT
GKLSIRPSPFDLSELVTQLLESFAAQIAAANSTITRFAEQPVIGVWDEFRIEQVVANLLTNALRYGARKPIEVHVYSKDS
EAFIEVRDQGIGITAENQKRIFQQFERVSSNHAVAGLGLGLFISDQIVMAHGGRIEVESEEGKGSVFRICLPL

Sequences:

>Translated_393_residues
MLSEIQAKLLIVDDLPENLLALEALIKRGDRIVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRSTEKTKS
IPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQRKAMKIQVEELERSRQEQEALLKRLQSTQG
ELEHAIRMRDDFMSIVSHEVRTPLNGLILETQLRKLHLAKDNAAAFTMEKLRAMVDRDERQIQSLIRLIEDMLDVSRIRT
GKLSIRPSPFDLSELVTQLLESFAAQIAAANSTITRFAEQPVIGVWDEFRIEQVVANLLTNALRYGARKPIEVHVYSKDS
EAFIEVRDQGIGITAENQKRIFQQFERVSSNHAVAGLGLGLFISDQIVMAHGGRIEVESEEGKGSVFRICLPL
>Mature_393_residues
MLSEIQAKLLIVDDLPENLLALEALIKRGDRIVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRSTEKTKS
IPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQRKAMKIQVEELERSRQEQEALLKRLQSTQG
ELEHAIRMRDDFMSIVSHEVRTPLNGLILETQLRKLHLAKDNAAAFTMEKLRAMVDRDERQIQSLIRLIEDMLDVSRIRT
GKLSIRPSPFDLSELVTQLLESFAAQIAAANSTITRFAEQPVIGVWDEFRIEQVVANLLTNALRYGARKPIEVHVYSKDS
EAFIEVRDQGIGITAENQKRIFQQFERVSSNHAVAGLGLGLFISDQIVMAHGGRIEVESEEGKGSVFRICLPL

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=284, Percent_Identity=32.3943661971831, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=31.1740890688259, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=32.6086956521739, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=26.953125, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=28.6852589641434, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=28.82096069869, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=28.936170212766, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=30.2222222222222, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=30, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=26.0683760683761, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=28.0769230769231, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=247, Percent_Identity=23.4817813765182, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=26.1802575107296, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44337; Mature: 44337

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEIQAKLLIVDDLPENLLALEALIKRGDRIVYKALSADEALSLLLQHEFAMAILDVQM
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEC
PGMNGFELAELMRSTEKTKSIPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCHHHHCCCCHHHHHHHH
VNVFVDLYRQRKAMKIQVEELERSRQEQEALLKRLQSTQGELEHAIRMRDDFMSIVSHEV
HHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNGLILETQLRKLHLAKDNAAAFTMEKLRAMVDRDERQIQSLIRLIEDMLDVSRIRT
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GKLSIRPSPFDLSELVTQLLESFAAQIAAANSTITRFAEQPVIGVWDEFRIEQVVANLLT
CCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NALRYGARKPIEVHVYSKDSEAFIEVRDQGIGITAENQKRIFQQFERVSSNHAVAGLGLG
HHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECEE
LFISDQIVMAHGGRIEVESEEGKGSVFRICLPL
HEEECEEEEECCCEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MLSEIQAKLLIVDDLPENLLALEALIKRGDRIVYKALSADEALSLLLQHEFAMAILDVQM
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEC
PGMNGFELAELMRSTEKTKSIPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCHHHHCCCCHHHHHHHH
VNVFVDLYRQRKAMKIQVEELERSRQEQEALLKRLQSTQGELEHAIRMRDDFMSIVSHEV
HHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNGLILETQLRKLHLAKDNAAAFTMEKLRAMVDRDERQIQSLIRLIEDMLDVSRIRT
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GKLSIRPSPFDLSELVTQLLESFAAQIAAANSTITRFAEQPVIGVWDEFRIEQVVANLLT
CCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NALRYGARKPIEVHVYSKDSEAFIEVRDQGIGITAENQKRIFQQFERVSSNHAVAGLGLG
HHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECEE
LFISDQIVMAHGGRIEVESEEGKGSVFRICLPL
HEEECEEEEECCCEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]