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The map label for this gene is xylB [H]

Identifier: 66045671

GI number: 66045671

Start: 2818968

End: 2820449

Strand: Reverse

Name: xylB [H]

Synonym: Psyr_2435

Alternate gene names: 66045671

Gene position: 2820449-2818968 (Counterclockwise)

Preceding gene: 66045672

Following gene: 66045670

Centisome position: 46.28

GC content: 63.56

Gene sequence:

>1482_bases
ATGTTTCTTGGAATCGATTGCGGGACCCAGGGCACCAAGGTGCTGGTGCTCGACACCGAAAGCGGCACCGTGCTGGGCGA
AGGCTCGGCGCCGCACAGCCTGATCAGCGACCATAACGGACGCCGTGAACAGGACGTGCAGCAATGGCTGGACGCCCTGC
AACAGGCGACCCGCGAGGCACTGGCAGCGTCGGGCGTTTCCGGTCAGCAGATTCAGGGCATCGGGGTCTCAGGCCAGCAA
CATGGCCTGGTGCTGCTCGATGCTCAAGGCCAGGTACTGCGCCCGGCCAAACTGTGGTGCGATACCGAGTCGGCACCGGA
AAACCAGCGCCTGCTGGACTTTCTGGGCGGCGCGCAGGGTTCGCTGCAACGCCTTGGCCTGGTCATTGCCCCAGGCTATA
CCGTGTCGAAACTGCTGTGGACCAAGGAGCAATACCCGGATCTGTTCGAGCGGATCGACAAGGTGCTGCTGCCCCACGAC
TACCTCAACTATTGGCTGACCGGCCGCTGCTGCACCGAGTTTGGCGACGCATCGGGCACCGGTTACTTCAACGTGCGCAC
TCGCGAGTGGGACCTGCCGTTGCTCGCGCACATCGACCCGAGCGGTCGCCTGGGCAAGGCACTTCCACAGCTGTTGCAAG
CCCATGAACCGGTGGGCGCACTGCGTGCTGAGGTCGCCCGGCTGCTGGGCCTGAACCCTGACGCGCTGGTCTCCAGTGGC
GGCGGCGACAACATGATGGGCGCGATCGGCACAGGCAATATCCAGCCGGGGCTGATCACCATGAGCCTGGGCTCTTCGGG
CACCGTGTATGCCTACGCCGATGAGGCGCAGGTCAGTGAGCATGAGTCGGTCGCGACGTTCTGCTCATCCTCAGGCGGCT
GGTTGCCGCTGATCTGCACGATGAACCTGACCAACGCAACGACTGCCATTCGCGAGTTGTTCGCCCTCGACATCGGCGGC
TTCAACCAGGTGGTCGCCCAGGCGCCGATCGGTGCCGAAGGCGTACTGATGCTGCCCTTTCTGAACGGCGAACGCGTGCC
CGCCCTGCCCGACGCTACCGGCAGCATCGTCGGGCTGGACAGCACCAATCTGACCCAGGCCAACCTGTCCCGTGCGGTGG
TCGAAGGCACTACCTTCGGCCTTCGCTACGGGCTCGACCTGTTACGCGACAGCGGTATCAAAAGCGAAAAGATCCGTCTG
ATCGGCGGTGGCTCCAAAAGTGCCGTGTGGCGGCAGATCGTGGCCGACATCATGAACACTCCGGTGATCTGCACCGACCA
CTCGGAAGCCGCCGCGCTGGGCGCCGCCATTCAAGCGGCCTGGTGCTGGTCGCGCGCCAACGGCAAAGCTCAGGACCTGC
AGCAACTGTGTGAACGCTGCGTGAGTCTCGATCAGAGCAGTGAGACGCATCCTGTGGTGCATAATGTGGCCGCCTACCAG
CAGGTCTATCAGGGTTATCAGGCGCAATTGCGCAAGGTTTGA

Upstream 100 bases:

>100_bases
TTCGTGGCGGCCTTCGAGCAGAACCTCAATGATCTCCGCACACTGGGTGTGAGTGGCACACTGGAAAAACTTTTGGCCGC
CAAGGCCTGAGGGAATTCCC

Downstream 100 bases:

>100_bases
AGCGTTTTTTCATGGAGCACTTATGTTTCTGGTTTGTGGCGAAGCACTGTTCGATATTTTTACCCGCGCGGATGACAGCG
GTTCCCTGAACAGATTGGGG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MFLGIDCGTQGTKVLVLDTESGTVLGEGSAPHSLISDHNGRREQDVQQWLDALQQATREALAASGVSGQQIQGIGVSGQQ
HGLVLLDAQGQVLRPAKLWCDTESAPENQRLLDFLGGAQGSLQRLGLVIAPGYTVSKLLWTKEQYPDLFERIDKVLLPHD
YLNYWLTGRCCTEFGDASGTGYFNVRTREWDLPLLAHIDPSGRLGKALPQLLQAHEPVGALRAEVARLLGLNPDALVSSG
GGDNMMGAIGTGNIQPGLITMSLGSSGTVYAYADEAQVSEHESVATFCSSSGGWLPLICTMNLTNATTAIRELFALDIGG
FNQVVAQAPIGAEGVLMLPFLNGERVPALPDATGSIVGLDSTNLTQANLSRAVVEGTTFGLRYGLDLLRDSGIKSEKIRL
IGGGSKSAVWRQIVADIMNTPVICTDHSEAAALGAAIQAAWCWSRANGKAQDLQQLCERCVSLDQSSETHPVVHNVAAYQ
QVYQGYQAQLRKV

Sequences:

>Translated_493_residues
MFLGIDCGTQGTKVLVLDTESGTVLGEGSAPHSLISDHNGRREQDVQQWLDALQQATREALAASGVSGQQIQGIGVSGQQ
HGLVLLDAQGQVLRPAKLWCDTESAPENQRLLDFLGGAQGSLQRLGLVIAPGYTVSKLLWTKEQYPDLFERIDKVLLPHD
YLNYWLTGRCCTEFGDASGTGYFNVRTREWDLPLLAHIDPSGRLGKALPQLLQAHEPVGALRAEVARLLGLNPDALVSSG
GGDNMMGAIGTGNIQPGLITMSLGSSGTVYAYADEAQVSEHESVATFCSSSGGWLPLICTMNLTNATTAIRELFALDIGG
FNQVVAQAPIGAEGVLMLPFLNGERVPALPDATGSIVGLDSTNLTQANLSRAVVEGTTFGLRYGLDLLRDSGIKSEKIRL
IGGGSKSAVWRQIVADIMNTPVICTDHSEAAALGAAIQAAWCWSRANGKAQDLQQLCERCVSLDQSSETHPVVHNVAAYQ
QVYQGYQAQLRKV
>Mature_493_residues
MFLGIDCGTQGTKVLVLDTESGTVLGEGSAPHSLISDHNGRREQDVQQWLDALQQATREALAASGVSGQQIQGIGVSGQQ
HGLVLLDAQGQVLRPAKLWCDTESAPENQRLLDFLGGAQGSLQRLGLVIAPGYTVSKLLWTKEQYPDLFERIDKVLLPHD
YLNYWLTGRCCTEFGDASGTGYFNVRTREWDLPLLAHIDPSGRLGKALPQLLQAHEPVGALRAEVARLLGLNPDALVSSG
GGDNMMGAIGTGNIQPGLITMSLGSSGTVYAYADEAQVSEHESVATFCSSSGGWLPLICTMNLTNATTAIRELFALDIGG
FNQVVAQAPIGAEGVLMLPFLNGERVPALPDATGSIVGLDSTNLTQANLSRAVVEGTTFGLRYGLDLLRDSGIKSEKIRL
IGGGSKSAVWRQIVADIMNTPVICTDHSEAAALGAAIQAAWCWSRANGKAQDLQQLCERCVSLDQSSETHPVVHNVAAYQ
QVYQGYQAQLRKV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI18860918, Length=480, Percent_Identity=22.5, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI41393575, Length=440, Percent_Identity=23.4090909090909, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI42794763, Length=444, Percent_Identity=23.1981981981982, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI189409120, Length=444, Percent_Identity=23.4234234234234, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4504007, Length=444, Percent_Identity=23.4234234234234, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789987, Length=498, Percent_Identity=35.140562248996, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1790005, Length=456, Percent_Identity=29.3859649122807, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787789, Length=522, Percent_Identity=24.1379310344828, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789168, Length=452, Percent_Identity=26.9911504424779, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790361, Length=495, Percent_Identity=26.0606060606061, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790338, Length=201, Percent_Identity=29.3532338308458, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554530, Length=543, Percent_Identity=22.6519337016575, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321633, Length=457, Percent_Identity=23.4135667396061, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356607, Length=501, Percent_Identity=23.3532934131737, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24655555, Length=459, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655560, Length=459, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655570, Length=459, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655574, Length=459, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655565, Length=459, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52619; Mature: 52619

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGIDCGTQGTKVLVLDTESGTVLGEGSAPHSLISDHNGRREQDVQQWLDALQQATREA
CEEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAASGVSGQQIQGIGVSGQQHGLVLLDAQGQVLRPAKLWCDTESAPENQRLLDFLGGAQG
HHHCCCCCCEEEEECCCCCCCCEEEECCCCCEECCHHHEECCCCCCCHHHHHHHHCCCCC
SLQRLGLVIAPGYTVSKLLWTKEQYPDLFERIDKVLLPHDYLNYWLTGRCCTEFGDASGT
CHHHCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHEECCHHHHHCCCCCCC
GYFNVRTREWDLPLLAHIDPSGRLGKALPQLLQAHEPVGALRAEVARLLGLNPDALVSSG
EEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHEECC
GGDNMMGAIGTGNIQPGLITMSLGSSGTVYAYADEAQVSEHESVATFCSSSGGWLPLICT
CCCCCEEEEECCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
MNLTNATTAIRELFALDIGGFNQVVAQAPIGAEGVLMLPFLNGERVPALPDATGSIVGLD
ECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEECC
STNLTQANLSRAVVEGTTFGLRYGLDLLRDSGIKSEKIRLIGGGSKSAVWRQIVADIMNT
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
PVICTDHSEAAALGAAIQAAWCWSRANGKAQDLQQLCERCVSLDQSSETHPVVHNVAAYQ
CEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QVYQGYQAQLRKV
HHHHHHHHHHHCC
>Mature Secondary Structure
MFLGIDCGTQGTKVLVLDTESGTVLGEGSAPHSLISDHNGRREQDVQQWLDALQQATREA
CEEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAASGVSGQQIQGIGVSGQQHGLVLLDAQGQVLRPAKLWCDTESAPENQRLLDFLGGAQG
HHHCCCCCCEEEEECCCCCCCCEEEECCCCCEECCHHHEECCCCCCCHHHHHHHHCCCCC
SLQRLGLVIAPGYTVSKLLWTKEQYPDLFERIDKVLLPHDYLNYWLTGRCCTEFGDASGT
CHHHCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHEECCHHHHHCCCCCCC
GYFNVRTREWDLPLLAHIDPSGRLGKALPQLLQAHEPVGALRAEVARLLGLNPDALVSSG
EEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHEECC
GGDNMMGAIGTGNIQPGLITMSLGSSGTVYAYADEAQVSEHESVATFCSSSGGWLPLICT
CCCCCEEEEECCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
MNLTNATTAIRELFALDIGGFNQVVAQAPIGAEGVLMLPFLNGERVPALPDATGSIVGLD
ECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEECC
STNLTQANLSRAVVEGTTFGLRYGLDLLRDSGIKSEKIRLIGGGSKSAVWRQIVADIMNT
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
PVICTDHSEAAALGAAIQAAWCWSRANGKAQDLQQLCERCVSLDQSSETHPVVHNVAAYQ
CEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QVYQGYQAQLRKV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]