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The map label for this gene is nhaR [H]

Identifier: 66045658

GI number: 66045658

Start: 2804303

End: 2805205

Strand: Reverse

Name: nhaR [H]

Synonym: Psyr_2422

Alternate gene names: 66045658

Gene position: 2805205-2804303 (Counterclockwise)

Preceding gene: 66045661

Following gene: 66045655

Centisome position: 46.03

GC content: 59.47

Gene sequence:

>903_bases
ATGCTCAATTACCGCCAACTCCACTACTTCTGGGTCGTGGCCAAGACCGGCAGCATCGTGCGCGCCTGCGAACAGCTGAA
TCTGACCGCGCAGACTGTCAGCGGGCAGATCAGCCTGCTCGAGGCGTCGCTTGGGGTCGATCTGTTCCAGCGCGTCGGTC
GGCAGCTGGAAATGACCGAAGCAGGCCGCCTCGCCCTGCCCTATGCCGAACAGATGTTTCAGTTGGGCAATGACCTGGAA
AACCTGTTGCGCTCACAGCCGGATGAACAGCAATTGCTGTTGCGCATTGGGGTGGCCGACGTCGTGCCCAAGTCCATTGT
CTACCGCCTGATTGCCCCGACCATGACGCTGGATGAGTCCATTCGCATCACCTGTCGCGAGGACAAGCTGGAACGACTGC
TGGCAGACCTGGCCATCCAGCGTCTGGACCTGGTGATTTCCGACAGCCCCATGCCGCCGCATCTGGACATCAAGGGCTAC
AGCCAGAAGCTGGGAGAATGCGGGGTCAGTTTTTTCGCCACGCGTGAAATGGCGGAGCGTATCGGGACAAATTTTCCGCA
GTGCATGCATGGAGCACCGCTGCTGATTCCGGGTCAGGAGACCGTGGTTCGAGGCAGACTGATGCGCTGGTTTGCCGAAC
AGGGCATTCAGCCACGCATCATCGGCGAATTCGATGACAGCGCACTGATGAAGGCGTTTGGCAAATCCGGCAGCGGCGTG
TTCGTGGCGCCCAGCGTGATCGCCGACGAAGTGCAGAACCAGTATGGCGTACAAGTGATTGGCCATACTGATGCGGTGAC
CGAATCGTTCTACGCCATCACCGTGGAGCGCAAGGTCAAGCACCCCGGCGTCGTCGCCATTGCCGAAAGTGCTCGGAATC
AGCTGTTTACCGATGCTGGCTAA

Upstream 100 bases:

>100_bases
GTTCAGCCCGGCGTTGGAGCGGATTCTAGACATCTTGAAACATAAGGAAAATTCGATTTTATAAGTCGTATACTTCGGTT
TTACCGAATCGGCTGAAATT

Downstream 100 bases:

>100_bases
GCCGGGAGCGGCCCCGGATCACGCTTGATCAACAGCAGCGCCAGCACAATCGCCAGCACAATGATGCCCGCAGCGGCAAA
ACCGACGTTGCCCAGCCCCA

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTAQTVSGQISLLEASLGVDLFQRVGRQLEMTEAGRLALPYAEQMFQLGNDLE
NLLRSQPDEQQLLLRIGVADVVPKSIVYRLIAPTMTLDESIRITCREDKLERLLADLAIQRLDLVISDSPMPPHLDIKGY
SQKLGECGVSFFATREMAERIGTNFPQCMHGAPLLIPGQETVVRGRLMRWFAEQGIQPRIIGEFDDSALMKAFGKSGSGV
FVAPSVIADEVQNQYGVQVIGHTDAVTESFYAITVERKVKHPGVVAIAESARNQLFTDAG

Sequences:

>Translated_300_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTAQTVSGQISLLEASLGVDLFQRVGRQLEMTEAGRLALPYAEQMFQLGNDLE
NLLRSQPDEQQLLLRIGVADVVPKSIVYRLIAPTMTLDESIRITCREDKLERLLADLAIQRLDLVISDSPMPPHLDIKGY
SQKLGECGVSFFATREMAERIGTNFPQCMHGAPLLIPGQETVVRGRLMRWFAEQGIQPRIIGEFDDSALMKAFGKSGSGV
FVAPSVIADEVQNQYGVQVIGHTDAVTESFYAITVERKVKHPGVVAIAESARNQLFTDAG
>Mature_300_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTAQTVSGQISLLEASLGVDLFQRVGRQLEMTEAGRLALPYAEQMFQLGNDLE
NLLRSQPDEQQLLLRIGVADVVPKSIVYRLIAPTMTLDESIRITCREDKLERLLADLAIQRLDLVISDSPMPPHLDIKGY
SQKLGECGVSFFATREMAERIGTNFPQCMHGAPLLIPGQETVVRGRLMRWFAEQGIQPRIIGEFDDSALMKAFGKSGSGV
FVAPSVIADEVQNQYGVQVIGHTDAVTESFYAITVERKVKHPGVVAIAESARNQLFTDAG

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=298, Percent_Identity=39.9328859060403, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI157672245, Length=256, Percent_Identity=26.5625, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33264; Mature: 33264

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYRQLHYFWVVAKTGSIVRACEQLNLTAQTVSGQISLLEASLGVDLFQRVGRQLEMTE
CCCCEEEEEEEEEECCCHHHHHHHHCCCHHHHHCCHHEEHHHHHCHHHHHHCCCEEECCC
AGRLALPYAEQMFQLGNDLENLLRSQPDEQQLLLRIGVADVVPKSIVYRLIAPTMTLDES
CCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IRITCREDKLERLLADLAIQRLDLVISDSPMPPHLDIKGYSQKLGECGVSFFATREMAER
EEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGTNFPQCMHGAPLLIPGQETVVRGRLMRWFAEQGIQPRIIGEFDDSALMKAFGKSGSGV
HCCCCCHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCCE
FVAPSVIADEVQNQYGVQVIGHTDAVTESFYAITVERKVKHPGVVAIAESARNQLFTDAG
EEEHHHHHHHHHHCCCEEEEECCHHHHHCEEEEEEECCCCCCCEEEEHHHHHHHHCCCCC
>Mature Secondary Structure
MLNYRQLHYFWVVAKTGSIVRACEQLNLTAQTVSGQISLLEASLGVDLFQRVGRQLEMTE
CCCCEEEEEEEEEECCCHHHHHHHHCCCHHHHHCCHHEEHHHHHCHHHHHHCCCEEECCC
AGRLALPYAEQMFQLGNDLENLLRSQPDEQQLLLRIGVADVVPKSIVYRLIAPTMTLDES
CCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IRITCREDKLERLLADLAIQRLDLVISDSPMPPHLDIKGYSQKLGECGVSFFATREMAER
EEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGTNFPQCMHGAPLLIPGQETVVRGRLMRWFAEQGIQPRIIGEFDDSALMKAFGKSGSGV
HCCCCCHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCCE
FVAPSVIADEVQNQYGVQVIGHTDAVTESFYAITVERKVKHPGVVAIAESARNQLFTDAG
EEEHHHHHHHHHHCCCEEEEECCHHHHHCEEEEEEECCCCCCCEEEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]