Click here to switch to the map view.

The map label for this gene is polB [H]

Identifier: 66045597

GI number: 66045597

Start: 2737422

End: 2739785

Strand: Direct

Name: polB [H]

Synonym: Psyr_2361

Alternate gene names: 66045597

Gene position: 2737422-2739785 (Clockwise)

Preceding gene: 66045595

Following gene: 66045599

Centisome position: 44.92

GC content: 60.87

Gene sequence:

>2364_bases
TTGGATGTACAGCAGGGCTTTATCCTGAGTCGGCACTGGCAAGACACGCCCGCCGGGACCGAGGTCGACTTCTGGTTGGC
CACCGATCAGGGCCCGCGCCATATTCGCCTGCCTTGCCAGCCCTCTGTCGCCTTTATTCCTGCCGAACAGGGTGAGCGGG
CCCGATCGTTGTTGCGTACCGAACGTGGCGTAGAACTGCGTCCGCTTGAGCTCTGTGATTTTCGTCACCGTCCGGTGCTG
GGTGTGTATTGCCAGCAGCACCGCCAGTTGATGAACATCGAAAAGTTGCTGCGCAGAGGCAATGTAGACGTCTATGAAGC
GGACATTCGCCCGCCGGAACGCTACCTGATGGAACGCTTCATCACCGCGCCGGTGCAGTTTGGCGGCACGCCGGATGCCG
ATGGGGTGCTGTGCGACGCGCAGATCAGACCATCGCCCGATTACCGTCCTAATCTGAGGCTGGTCTCGCTGGATATCGAA
ACCACCGCCCGCGGCGAGTTGTATTCGATTGCACTGGAGGGCTGTGGGCAGCGCCAGGTCTACATGCTGGGGCCGGCCAA
CGGTGGTGACGAGACGCTGGATTTTCAGCTCGATTATTGCGATACCCGCGCGCAGTTGCTCGAACGCCTGAACGACTGGC
TGGCGCTGCACGACCCTGATGCGATTATCGGCTGGAACGTTATCCAGTTCGATTTACGCGTGCTGCATGAGCATGCCCAG
CGCCTGCAAGTGCCGTTAAGGCTTGGGCGTGGCGGTGAAGCGATGGGCTGGCGTGAGCATGGCAGTCGCAACAACCATTT
TTTTGCCGAAGTGAGCGGGCGGCTGATCATCGACGGAATCGAGGCATTGCGCTCGGCGACCTGGAGCTTTCCGTCGTTCA
GCCTCGAATACGTCGCGCAGACTCTGCTGGGCGAAGGCAAGGCCATCGACACGCCTTATCAGCGTATGGACGAAATCAAC
CGCATGTTCGCCGAGGACAAACCGGCGCTGGCGCGTTACAACATCAAGGACTGCGAACTGGTCTCGCGCATCTTTGCCAA
GACCCAATTGCTGACCTTTCTGCTCGAGCGCGCCACGGTCACCGGTCTGCCTGCCGACCGCAGCGGCGGTTCGGTCGCGG
CTTTCTGCCATTTGTATATCCCGTTGATGCACCGCCAGGGTTTCGTGGCGCCCAACCTGGGCGAGCGCCTGCCAGAGGCC
AGCCCTGGCGGTTTTGTCATGGATTCCCAGCCAGGGCTGTATGAGTCGGTGCTGGTACTGGACTACAAGAGCCTTTATCC
GTCGATCATTCGTACCTTTCTGATTGATCCGGTGGGCTTGATCGAAGGCCTGCGCCATCCAGCGGACAGCGAGTCGGTGC
CGGGCTTTCGCGGCGCGCGCTTCTCGCGCACCCGTCACAGCCTGCCAGCCATCGTCGAGCGCGTGTGGCAAGGTCGGGAA
GCGGCCAAGCGCGAGCAGAACGCCCCCTTGTCCCAGGCGCTGAAAATCATCATGAATGCCTTCTACGGCGTGTTGGGCTC
GAGCGGCTGTCGCTTTTTCGATCCGCGCCTGGCTTCATCGATCACCCTGCGCGGGCATGAAATCATGCTCAAGACCCGCG
ACCTCATTCAGGCGCAGGGCTACACCGTGATCTATGGCGATACCGACTCGACCTTTGTCTGGCTGGGCCGTCCTCACGGC
CAGGAAGAGGCGGCAAGCATCGGCAAGGCGCTGGTGCAGCAGGTCAACCAGTGGTGGCGTGAGCACTTGCACACCGAGTA
CGGTCTGCACAGCGCCCTTGAACTGCAATACGAAACGCATTTTCGGCGCTTCCTGATGCCCACCGTGCGCGGTGCGGAGG
AGGGCAGCAAGAAGCGTTACGCCGGCCTGGTGACCCGTGCTGACGGTTCCGAAGAGATGGTCTACAAGGGCCTCGAAACG
GTACGCACCGACTGGTCGCCACTGGCTCAGCAGTTTCAGCAGGAGCTTTACCTGCGGATCTTCAAGCGTCAGCCGTATCA
GGATTACGTGCGTGACTACGTGCAACGCACCCTGTCAGGCGAGCTGGATGATCTGTTGATTTACCGCAAGCGCTTGCGTC
GCAAGCTCGATGACTACCAGCGTAATGTGCCGCCCCATGTACGCGCCGCGCGGCTGGCCGATGAATACAACGACCAGCAG
GGGCGACCGCGTCAGTACCAGAGTGGCGGCTGGATCAGCTACGTGATGACCACCGCCGGGCCGGAACCGCTGGAGATTCG
TCACGCCCCGATTGACTACGATCACTACGTGACTCGTCAGTTACAACCGCTGGCTGACGCGATCCTGCCGTTTGTGGACG
ACGATTTCAGCACCCTGATCGGCGGGCAACTGGGGTTGTTCTAA

Upstream 100 bases:

>100_bases
TCCATGCCCCTCAATGTGCCGCTAATTCGCCTCCAGACGCGCCTTTAGCCTCATAGCCAAGTAGAATCATTTGTTTCACC
GGGCGGTCGAGGTAACAGCG

Downstream 100 bases:

>100_bases
GGCGAAACCAACTGTTCGGCCAGCCACGGCAAGGCCTGCTCACAGGACGCTTCGATCTTCATTTCAAGCAGCTCGTCCGC
CCGGGTCTTGCCATGGTTGA

Product: DNA polymerase II

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MDVQQGFILSRHWQDTPAGTEVDFWLATDQGPRHIRLPCQPSVAFIPAEQGERARSLLRTERGVELRPLELCDFRHRPVL
GVYCQQHRQLMNIEKLLRRGNVDVYEADIRPPERYLMERFITAPVQFGGTPDADGVLCDAQIRPSPDYRPNLRLVSLDIE
TTARGELYSIALEGCGQRQVYMLGPANGGDETLDFQLDYCDTRAQLLERLNDWLALHDPDAIIGWNVIQFDLRVLHEHAQ
RLQVPLRLGRGGEAMGWREHGSRNNHFFAEVSGRLIIDGIEALRSATWSFPSFSLEYVAQTLLGEGKAIDTPYQRMDEIN
RMFAEDKPALARYNIKDCELVSRIFAKTQLLTFLLERATVTGLPADRSGGSVAAFCHLYIPLMHRQGFVAPNLGERLPEA
SPGGFVMDSQPGLYESVLVLDYKSLYPSIIRTFLIDPVGLIEGLRHPADSESVPGFRGARFSRTRHSLPAIVERVWQGRE
AAKREQNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHEIMLKTRDLIQAQGYTVIYGDTDSTFVWLGRPHG
QEEAASIGKALVQQVNQWWREHLHTEYGLHSALELQYETHFRRFLMPTVRGAEEGSKKRYAGLVTRADGSEEMVYKGLET
VRTDWSPLAQQFQQELYLRIFKRQPYQDYVRDYVQRTLSGELDDLLIYRKRLRRKLDDYQRNVPPHVRAARLADEYNDQQ
GRPRQYQSGGWISYVMTTAGPEPLEIRHAPIDYDHYVTRQLQPLADAILPFVDDDFSTLIGGQLGLF

Sequences:

>Translated_787_residues
MDVQQGFILSRHWQDTPAGTEVDFWLATDQGPRHIRLPCQPSVAFIPAEQGERARSLLRTERGVELRPLELCDFRHRPVL
GVYCQQHRQLMNIEKLLRRGNVDVYEADIRPPERYLMERFITAPVQFGGTPDADGVLCDAQIRPSPDYRPNLRLVSLDIE
TTARGELYSIALEGCGQRQVYMLGPANGGDETLDFQLDYCDTRAQLLERLNDWLALHDPDAIIGWNVIQFDLRVLHEHAQ
RLQVPLRLGRGGEAMGWREHGSRNNHFFAEVSGRLIIDGIEALRSATWSFPSFSLEYVAQTLLGEGKAIDTPYQRMDEIN
RMFAEDKPALARYNIKDCELVSRIFAKTQLLTFLLERATVTGLPADRSGGSVAAFCHLYIPLMHRQGFVAPNLGERLPEA
SPGGFVMDSQPGLYESVLVLDYKSLYPSIIRTFLIDPVGLIEGLRHPADSESVPGFRGARFSRTRHSLPAIVERVWQGRE
AAKREQNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHEIMLKTRDLIQAQGYTVIYGDTDSTFVWLGRPHG
QEEAASIGKALVQQVNQWWREHLHTEYGLHSALELQYETHFRRFLMPTVRGAEEGSKKRYAGLVTRADGSEEMVYKGLET
VRTDWSPLAQQFQQELYLRIFKRQPYQDYVRDYVQRTLSGELDDLLIYRKRLRRKLDDYQRNVPPHVRAARLADEYNDQQ
GRPRQYQSGGWISYVMTTAGPEPLEIRHAPIDYDHYVTRQLQPLADAILPFVDDDFSTLIGGQLGLF
>Mature_787_residues
MDVQQGFILSRHWQDTPAGTEVDFWLATDQGPRHIRLPCQPSVAFIPAEQGERARSLLRTERGVELRPLELCDFRHRPVL
GVYCQQHRQLMNIEKLLRRGNVDVYEADIRPPERYLMERFITAPVQFGGTPDADGVLCDAQIRPSPDYRPNLRLVSLDIE
TTARGELYSIALEGCGQRQVYMLGPANGGDETLDFQLDYCDTRAQLLERLNDWLALHDPDAIIGWNVIQFDLRVLHEHAQ
RLQVPLRLGRGGEAMGWREHGSRNNHFFAEVSGRLIIDGIEALRSATWSFPSFSLEYVAQTLLGEGKAIDTPYQRMDEIN
RMFAEDKPALARYNIKDCELVSRIFAKTQLLTFLLERATVTGLPADRSGGSVAAFCHLYIPLMHRQGFVAPNLGERLPEA
SPGGFVMDSQPGLYESVLVLDYKSLYPSIIRTFLIDPVGLIEGLRHPADSESVPGFRGARFSRTRHSLPAIVERVWQGRE
AAKREQNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHEIMLKTRDLIQAQGYTVIYGDTDSTFVWLGRPHG
QEEAASIGKALVQQVNQWWREHLHTEYGLHSALELQYETHFRRFLMPTVRGAEEGSKKRYAGLVTRADGSEEMVYKGLET
VRTDWSPLAQQFQQELYLRIFKRQPYQDYVRDYVQRTLSGELDDLLIYRKRLRRKLDDYQRNVPPHVRAARLADEYNDQQ
GRPRQYQSGGWISYVMTTAGPEPLEIRHAPIDYDHYVTRQLQPLADAILPFVDDDFSTLIGGQLGLF

Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=639, Percent_Identity=27.5430359937402, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI106507301, Length=648, Percent_Identity=25.462962962963, Blast_Score=138, Evalue=2e-32,
Organism=Escherichia coli, GI1786246, Length=785, Percent_Identity=67.515923566879, Blast_Score=1097, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559488, Length=709, Percent_Identity=26.7983074753174, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI32565317, Length=637, Percent_Identity=24.0188383045526, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320101, Length=703, Percent_Identity=25.3200568990043, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324227, Length=685, Percent_Identity=25.8394160583942, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24648780, Length=644, Percent_Identity=22.9813664596273, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24664937, Length=648, Percent_Identity=25.7716049382716, Blast_Score=124, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 89787; Mature: 89787

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVQQGFILSRHWQDTPAGTEVDFWLATDQGPRHIRLPCQPSVAFIPAEQGERARSLLRT
CCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCEEECCCCCCEEEEECCCCHHHHHHHHH
ERGVELRPLELCDFRHRPVLGVYCQQHRQLMNIEKLLRRGNVDVYEADIRPPERYLMERF
HCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHH
ITAPVQFGGTPDADGVLCDAQIRPSPDYRPNLRLVSLDIETTARGELYSIALEGCGQRQV
HHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEE
YMLGPANGGDETLDFQLDYCDTRAQLLERLNDWLALHDPDAIIGWNVIQFDLRVLHEHAQ
EEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHEEECCCCCEECCHHHHHHHHHHHHHHH
RLQVPLRLGRGGEAMGWREHGSRNNHFFAEVSGRLIIDGIEALRSATWSFPSFSLEYVAQ
HHHHHHEECCCCCCCCCHHCCCCCCEEEEEECCCEEEHHHHHHHHCCCCCCCCHHHHHHH
TLLGEGKAIDTPYQRMDEINRMFAEDKPALARYNIKDCELVSRIFAKTQLLTFLLERATV
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPADRSGGSVAAFCHLYIPLMHRQGFVAPNLGERLPEASPGGFVMDSQPGLYESVLVL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHH
DYKSLYPSIIRTFLIDPVGLIEGLRHPADSESVPGFRGARFSRTRHSLPAIVERVWQGRE
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
AAKREQNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHEIMLKTRDLIQAQG
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHCEEEECCCEEEEEHHHHHHHCC
YTVIYGDTDSTFVWLGRPHGQEEAASIGKALVQQVNQWWREHLHTEYGLHSALELQYETH
CEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FRRFLMPTVRGAEEGSKKRYAGLVTRADGSEEMVYKGLETVRTDWSPLAQQFQQELYLRI
HHHHHHHHHCCCCCCCCHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKRQPYQDYVRDYVQRTLSGELDDLLIYRKRLRRKLDDYQRNVPPHVRAARLADEYNDQQ
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GRPRQYQSGGWISYVMTTAGPEPLEIRHAPIDYDHYVTRQLQPLADAILPFVDDDFSTLI
CCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
GGQLGLF
CCCCCCC
>Mature Secondary Structure
MDVQQGFILSRHWQDTPAGTEVDFWLATDQGPRHIRLPCQPSVAFIPAEQGERARSLLRT
CCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCEEECCCCCCEEEEECCCCHHHHHHHHH
ERGVELRPLELCDFRHRPVLGVYCQQHRQLMNIEKLLRRGNVDVYEADIRPPERYLMERF
HCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHH
ITAPVQFGGTPDADGVLCDAQIRPSPDYRPNLRLVSLDIETTARGELYSIALEGCGQRQV
HHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEE
YMLGPANGGDETLDFQLDYCDTRAQLLERLNDWLALHDPDAIIGWNVIQFDLRVLHEHAQ
EEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHEEECCCCCEECCHHHHHHHHHHHHHHH
RLQVPLRLGRGGEAMGWREHGSRNNHFFAEVSGRLIIDGIEALRSATWSFPSFSLEYVAQ
HHHHHHEECCCCCCCCCHHCCCCCCEEEEEECCCEEEHHHHHHHHCCCCCCCCHHHHHHH
TLLGEGKAIDTPYQRMDEINRMFAEDKPALARYNIKDCELVSRIFAKTQLLTFLLERATV
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPADRSGGSVAAFCHLYIPLMHRQGFVAPNLGERLPEASPGGFVMDSQPGLYESVLVL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHH
DYKSLYPSIIRTFLIDPVGLIEGLRHPADSESVPGFRGARFSRTRHSLPAIVERVWQGRE
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
AAKREQNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHEIMLKTRDLIQAQG
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHCEEEECCCEEEEEHHHHHHHCC
YTVIYGDTDSTFVWLGRPHGQEEAASIGKALVQQVNQWWREHLHTEYGLHSALELQYETH
CEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FRRFLMPTVRGAEEGSKKRYAGLVTRADGSEEMVYKGLETVRTDWSPLAQQFQQELYLRI
HHHHHHHHHCCCCCCCCHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKRQPYQDYVRDYVQRTLSGELDDLLIYRKRLRRKLDDYQRNVPPHVRAARLADEYNDQQ
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GRPRQYQSGGWISYVMTTAGPEPLEIRHAPIDYDHYVTRQLQPLADAILPFVDDDFSTLI
CCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
GGQLGLF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]