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The map label for this gene is kdgR [H]

Identifier: 66045573

GI number: 66045573

Start: 2713737

End: 2714576

Strand: Direct

Name: kdgR [H]

Synonym: Psyr_2336

Alternate gene names: 66045573

Gene position: 2713737-2714576 (Clockwise)

Preceding gene: 66045563

Following gene: 66045579

Centisome position: 44.53

GC content: 64.17

Gene sequence:

>840_bases
ATGGATAATTCCACTGATCGGAATAACGTGAAGGCCGAGGTCGGAGTGGGAGCCGTTTCCCGGCTGTTCGCGGTACTGCG
CTGTCTGGGCGATTGTGATGAAGGCGGTGAGCGGGTCACGCAACTCGCCCAGCGTGTCGGGCTGTCGCAACCCACCACAC
ACCGCTTGCTGCGTAGCCTGATGGAGGAGGGCATGGTCGAGCAGGATCTGCTCAGCAAACGTTATCGGTTGAGCATCGAG
TTCTTCGCCCTGGCCGCCAAGGCGGGTAATACCGGCAACCTGCGTGACGTGGTGCGCCCAAGCCTTTTGCGCCTGTCCGC
CTCACTGGGTGACTCGCTGTTTCTGCTGGCACGCAGCGGTTTCGACGCGATCTGCCTGGACCGCAGCGAAGGCCCGTACC
CGATACGCACGTTCACCGGCGACATCGGCGGCCGTGTTGCCTTGGGCGTCGGGCAGGGCAGTCTGGCGATTCTCGCGTTT
CTGCCCGAGGACGAGCGGGAAACGGTCATTGCCTACAACCTGCCACGGCTCAAGGATTTTCACCTGTACGACGAGGTGTT
TCTGCGTTCGGAGGTGGAAAACGTGCGGCGCCTGGGCTACGCCGGGCGCAACACCGGTGCGCTTCCGGGCATGGCCGGGC
TGGCAGTGCCGATCCTGGACCGCAGCGGTCGTGCGGTGGCTGCGCTCAGTGTGGCGACCATCTTCGACCGGCTGGGGCCG
GATCGCCTGATGACCGTGGTCGAACTGCTCAAGCGCGAAGCCACGGCCATCAGTGCCAGAATCAACCCGTTCGACCCGTC
GCTGCGGCGGCCCAGCCAGGTGTTCGGGCAGGTTGATTAG

Upstream 100 bases:

>100_bases
AGAGTAGGGCGAAGGCTAGGATGGGCTCAACAAGGAATTTCACTGAATAACATCTTTCTTTGAATTAATTCTTTTGGTGG
AAATATAAAGAGATATTGTC

Downstream 100 bases:

>100_bases
GCAGGATGCCTGTTCAGCTTCGAAGCGGCTGTCGGTCTTCTTTCGTTACGCCCATCCGCTGCGGCTCAGGCCTTCTGCCT
TGAACACCAGCGCCTTCAAG

Product: regulatory proteins, IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDNSTDRNNVKAEVGVGAVSRLFAVLRCLGDCDEGGERVTQLAQRVGLSQPTTHRLLRSLMEEGMVEQDLLSKRYRLSIE
FFALAAKAGNTGNLRDVVRPSLLRLSASLGDSLFLLARSGFDAICLDRSEGPYPIRTFTGDIGGRVALGVGQGSLAILAF
LPEDERETVIAYNLPRLKDFHLYDEVFLRSEVENVRRLGYAGRNTGALPGMAGLAVPILDRSGRAVAALSVATIFDRLGP
DRLMTVVELLKREATAISARINPFDPSLRRPSQVFGQVD

Sequences:

>Translated_279_residues
MDNSTDRNNVKAEVGVGAVSRLFAVLRCLGDCDEGGERVTQLAQRVGLSQPTTHRLLRSLMEEGMVEQDLLSKRYRLSIE
FFALAAKAGNTGNLRDVVRPSLLRLSASLGDSLFLLARSGFDAICLDRSEGPYPIRTFTGDIGGRVALGVGQGSLAILAF
LPEDERETVIAYNLPRLKDFHLYDEVFLRSEVENVRRLGYAGRNTGALPGMAGLAVPILDRSGRAVAALSVATIFDRLGP
DRLMTVVELLKREATAISARINPFDPSLRRPSQVFGQVD
>Mature_279_residues
MDNSTDRNNVKAEVGVGAVSRLFAVLRCLGDCDEGGERVTQLAQRVGLSQPTTHRLLRSLMEEGMVEQDLLSKRYRLSIE
FFALAAKAGNTGNLRDVVRPSLLRLSASLGDSLFLLARSGFDAICLDRSEGPYPIRTFTGDIGGRVALGVGQGSLAILAF
LPEDERETVIAYNLPRLKDFHLYDEVFLRSEVENVRRLGYAGRNTGALPGMAGLAVPILDRSGRAVAALSVATIFDRLGP
DRLMTVVELLKREATAISARINPFDPSLRRPSQVFGQVD

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=252, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=24.7011952191235, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786715, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786468, Length=222, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30417; Mature: 30417

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNSTDRNNVKAEVGVGAVSRLFAVLRCLGDCDEGGERVTQLAQRVGLSQPTTHRLLRSL
CCCCCCCCCCEEHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
MEEGMVEQDLLSKRYRLSIEFFALAAKAGNTGNLRDVVRPSLLRLSASLGDSLFLLARSG
HHCCCHHHHHHHHHHHEEEEHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
FDAICLDRSEGPYPIRTFTGDIGGRVALGVGQGSLAILAFLPEDERETVIAYNLPRLKDF
CCEEEEECCCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEECCCCCCHH
HLYDEVFLRSEVENVRRLGYAGRNTGALPGMAGLAVPILDRSGRAVAALSVATIFDRLGP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCEEEEECCCCCCHHHHHHHHHHHHCCH
DRLMTVVELLKREATAISARINPFDPSLRRPSQVFGQVD
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MDNSTDRNNVKAEVGVGAVSRLFAVLRCLGDCDEGGERVTQLAQRVGLSQPTTHRLLRSL
CCCCCCCCCCEEHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
MEEGMVEQDLLSKRYRLSIEFFALAAKAGNTGNLRDVVRPSLLRLSASLGDSLFLLARSG
HHCCCHHHHHHHHHHHEEEEHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
FDAICLDRSEGPYPIRTFTGDIGGRVALGVGQGSLAILAFLPEDERETVIAYNLPRLKDF
CCEEEEECCCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEECCCCCCHH
HLYDEVFLRSEVENVRRLGYAGRNTGALPGMAGLAVPILDRSGRAVAALSVATIFDRLGP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCEEEEECCCCCCHHHHHHHHHHHHCCH
DRLMTVVELLKREATAISARINPFDPSLRRPSQVFGQVD
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]