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The map label for this gene is cpg2 [H]

Identifier: 66045501

GI number: 66045501

Start: 2625734

End: 2626885

Strand: Reverse

Name: cpg2 [H]

Synonym: Psyr_2261

Alternate gene names: 66045501

Gene position: 2626885-2625734 (Counterclockwise)

Preceding gene: 66045502

Following gene: 66045500

Centisome position: 43.11

GC content: 63.63

Gene sequence:

>1152_bases
ATGAATGAAGCACAACTGCACGCCAGTGCGTGGCTGGCTGAGCAATATGAGGCGATGGAAGCGCTGCTGCAGCGCCTGGT
CGATACCGATTCCAACAGTTATGACAAGGTCGGCGTCGACGCAGTCGGTGAGCTGCTTGTCGAGCAGTTGCAGGTCGATG
GTATCGACGTCACACGCATCCCGGTCGAAGGGTTTGGCGATGTACTACTCGCCGAGTTGCCCGGTGGCCCCGGAAAACCG
GTGCTGTTGCTTGGGCACCGCGACACGGTGTTTCCGAAAGGCACCACGTCCACCCGCGGCTATACCAGGGACGCCGAGCT
GGCCTACGGCCCTGGCGTGGCCGACATGAAAGGCGGACTGGTGCTCAACTGCTTTGCGCTGAAGGCGTTGAAGCGCGCAG
GCCCGCTGCCGTTCCCGGTGCAGATTCTGTATACCGGCGACGAGGAAATCGGCTCCGCCAGCGCTCGCAATCACATCGAA
CACTACGCCCGCCAGGCGCGCGCGGTGCTCAACCCCGAGCCGGGACGCGCCAGTGGCAATGTGGTCAGCGCGCGCAAAGG
CGGTGCCACGCTGATCATCGAAGTCAGCGGCCGCGCGGCGCATTCAGGGGTCAATCATGCCGACGGCGCCAGCGCCATTC
AGGCGCTGGCGCACAAGATAATCAAGTTGCATGCGTTGACTGATTACGCGGCGGGCATCACCACCAATGTCGGGCTGATC
TCCGGCGGTACCTCCAGCAATACGGTAGCGCCCAGCGCCACGGCGAAGCTCGACGTGCGTTTTGTCGAGCTTCGCCAATG
GGCGGAAATACTTGCAGCCGTGCAGGCTATCGTCGCCGAAGAGGAACTGTCCGGCACGTCGGCCAGACTGCTGGAAGCCA
CCACCTTCCTGCCGATGGAAGCCCGGCACAGTACCGAGTTGCTGAGTATTTATCAGGGCCTCGCGCAGGAGCTGGGTTTT
AGCGTTGAGGGCGAATTCACCGGAGGCTGCGCCGACTCGGGCTTCACCGCCAGCCTGGGGATCCCGACCCTGTGCGGCCT
TGGCCCGGTGGGCGGCAAGGTCCACACCGACCGCGAGTACCTGGAACTGAACACCTTGGTGCCCAGAGGCCAGGCACTGG
TCGCGACGATTCTGGCGCTGGGGGACGTGTGA

Upstream 100 bases:

>100_bases
TGGTCAAGGAGAGCCTGCAAATCATGGCCGGACTGTTCTGGGACCTGGGCACGGACGGCGCACGACTGACCCGGGAACAG
CGGGCACAGGAGCTGAGTGA

Downstream 100 bases:

>100_bases
CGCAGAGCGTCACGAACTGCATTCCCACGCGGAGCGTGCGGAACGATGAACATTCGGGCCAGTATCGTACCCATACTCCG
CACACAGCGTTATACCTAAG

Product: peptidase M20:peptidase M20

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNEAQLHASAWLAEQYEAMEALLQRLVDTDSNSYDKVGVDAVGELLVEQLQVDGIDVTRIPVEGFGDVLLAELPGGPGKP
VLLLGHRDTVFPKGTTSTRGYTRDAELAYGPGVADMKGGLVLNCFALKALKRAGPLPFPVQILYTGDEEIGSASARNHIE
HYARQARAVLNPEPGRASGNVVSARKGGATLIIEVSGRAAHSGVNHADGASAIQALAHKIIKLHALTDYAAGITTNVGLI
SGGTSSNTVAPSATAKLDVRFVELRQWAEILAAVQAIVAEEELSGTSARLLEATTFLPMEARHSTELLSIYQGLAQELGF
SVEGEFTGGCADSGFTASLGIPTLCGLGPVGGKVHTDREYLELNTLVPRGQALVATILALGDV

Sequences:

>Translated_383_residues
MNEAQLHASAWLAEQYEAMEALLQRLVDTDSNSYDKVGVDAVGELLVEQLQVDGIDVTRIPVEGFGDVLLAELPGGPGKP
VLLLGHRDTVFPKGTTSTRGYTRDAELAYGPGVADMKGGLVLNCFALKALKRAGPLPFPVQILYTGDEEIGSASARNHIE
HYARQARAVLNPEPGRASGNVVSARKGGATLIIEVSGRAAHSGVNHADGASAIQALAHKIIKLHALTDYAAGITTNVGLI
SGGTSSNTVAPSATAKLDVRFVELRQWAEILAAVQAIVAEEELSGTSARLLEATTFLPMEARHSTELLSIYQGLAQELGF
SVEGEFTGGCADSGFTASLGIPTLCGLGPVGGKVHTDREYLELNTLVPRGQALVATILALGDV
>Mature_383_residues
MNEAQLHASAWLAEQYEAMEALLQRLVDTDSNSYDKVGVDAVGELLVEQLQVDGIDVTRIPVEGFGDVLLAELPGGPGKP
VLLLGHRDTVFPKGTTSTRGYTRDAELAYGPGVADMKGGLVLNCFALKALKRAGPLPFPVQILYTGDEEIGSASARNHIE
HYARQARAVLNPEPGRASGNVVSARKGGATLIIEVSGRAAHSGVNHADGASAIQALAHKIIKLHALTDYAAGITTNVGLI
SGGTSSNTVAPSATAKLDVRFVELRQWAEILAAVQAIVAEEELSGTSARLLEATTFLPMEARHSTELLSIYQGLAQELGF
SVEGEFTGGCADSGFTASLGIPTLCGLGPVGGKVHTDREYLELNTLVPRGQALVATILALGDV

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=369, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 40109; Mature: 40109

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAQLHASAWLAEQYEAMEALLQRLVDTDSNSYDKVGVDAVGELLVEQLQVDGIDVTRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
PVEGFGDVLLAELPGGPGKPVLLLGHRDTVFPKGTTSTRGYTRDAELAYGPGVADMKGGL
CCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCE
VLNCFALKALKRAGPLPFPVQILYTGDEEIGSASARNHIEHYARQARAVLNPEPGRASGN
EEHHHHHHHHHHCCCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVSARKGGATLIIEVSGRAAHSGVNHADGASAIQALAHKIIKLHALTDYAAGITTNVGLI
EEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
SGGTSSNTVAPSATAKLDVRFVELRQWAEILAAVQAIVAEEELSGTSARLLEATTFLPME
ECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
ARHSTELLSIYQGLAQELGFSVEGEFTGGCADSGFTASLGIPTLCGLGPVGGKVHTDREY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCCCCCCEECCHHH
LELNTLVPRGQALVATILALGDV
EEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNEAQLHASAWLAEQYEAMEALLQRLVDTDSNSYDKVGVDAVGELLVEQLQVDGIDVTRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
PVEGFGDVLLAELPGGPGKPVLLLGHRDTVFPKGTTSTRGYTRDAELAYGPGVADMKGGL
CCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCE
VLNCFALKALKRAGPLPFPVQILYTGDEEIGSASARNHIEHYARQARAVLNPEPGRASGN
EEHHHHHHHHHHCCCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVSARKGGATLIIEVSGRAAHSGVNHADGASAIQALAHKIIKLHALTDYAAGITTNVGLI
EEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
SGGTSSNTVAPSATAKLDVRFVELRQWAEILAAVQAIVAEEELSGTSARLLEATTFLPME
ECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
ARHSTELLSIYQGLAQELGFSVEGEFTGGCADSGFTASLGIPTLCGLGPVGGKVHTDREY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCCCCCCEECCHHH
LELNTLVPRGQALVATILALGDV
EEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]