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The map label for this gene is feaR [H]

Identifier: 66045453

GI number: 66045453

Start: 2571752

End: 2572681

Strand: Reverse

Name: feaR [H]

Synonym: Psyr_2213

Alternate gene names: 66045453

Gene position: 2572681-2571752 (Counterclockwise)

Preceding gene: 66045457

Following gene: 66045452

Centisome position: 42.22

GC content: 58.49

Gene sequence:

>930_bases
ATGGCCATGATTTTCCCAGCCGAACCACTACGACCCGAGGATCGTTTCGACGCCTGGCAGGAGGTTGTGAGTTCGACGTA
TGGCCTGGTCGCCAGCCAGCCCCTGAACGAAGCGCCGTTTGACGGCAGACTGAACGTCAGGGGTCAGGGTAGCGTTACTT
TCACCCGGATCCAGTCATCCCCCCTGCATTACCGGCGCTTGCAGCAAGACAGGGAAAGCGATCACTTCCTCCTCACGCTC
TCTTTGTGTCCCGACGCGCTTGTCGTGCAGAACGACAGGGAGTCCCGGCAAGGCGCTGGCGATATCGTCCTTTACGATAG
CGCACAGCCTTACGCATGCCGTTACCCCGAAGGGGACGATCAGATTGTCCTGACGGTGCCCCGCAAGCTGTTGCTGCAAC
ACATCCCCAGTGCCGAACGACTGGTGTGCCGGACGCTGGATGGCCATTCGGCATTGGGTCGTGTTGCCGCCGTCGTGTTG
ACCGAAGCCTGGAACGCAGAGGGTTTATCGGACCCGCTGAGCGAACGACTCAATGCATCACTGCTGGACGTACTGTCTAC
CGCCTTCGACTCGGTGTTTGGCGACACCGATATCCGACGTCAGTCTCATCAAATGCAACAACTGCAGCGCATCAAGCAAT
TCCTGCTGAATAATCTGCCCGACACAGGGCTGACGGCCGAAAACATTGCCTTGGCGACTCATGTCTCCCCACGCACACTC
AATCGACTGTTCGCACGGGAAGGCACTACGGCCATTCGCTGGCTCTGGCAGCAAAGGCTTTCGGCGTGCCATGACGCACT
GCTCAAACGCCACGTTCGCCGGGTCAGCGACGCTGCGCTGAATTTCGGCTTCACCAACCTCTCGCATTTCAGTCGAGCCT
TCAAAAACGCTTATGGCATTCCTCCCCAGCAGTTGCTGGAGCCACGATAA

Upstream 100 bases:

>100_bases
CACACTGGAGCACTGTAGACGCAGGGGTCTTGCTCTGGATCAACGTCTGATAACCTTGAAGCCGATCACTTCGTGAAAAA
CGCTCTTCGCAGAGGCAGAC

Downstream 100 bases:

>100_bases
GACGACTGGCGTCTTCGGCACAGCGATTGACCGTTCAGGCAAAGCACGCCGCATCCGGGTCGATCAGTATCACCGCCCTA
CTGACGGCGCTTTCTGCGCG

Product: helix-turn-helix, AraC type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAMIFPAEPLRPEDRFDAWQEVVSSTYGLVASQPLNEAPFDGRLNVRGQGSVTFTRIQSSPLHYRRLQQDRESDHFLLTL
SLCPDALVVQNDRESRQGAGDIVLYDSAQPYACRYPEGDDQIVLTVPRKLLLQHIPSAERLVCRTLDGHSALGRVAAVVL
TEAWNAEGLSDPLSERLNASLLDVLSTAFDSVFGDTDIRRQSHQMQQLQRIKQFLLNNLPDTGLTAENIALATHVSPRTL
NRLFAREGTTAIRWLWQQRLSACHDALLKRHVRRVSDAALNFGFTNLSHFSRAFKNAYGIPPQQLLEPR

Sequences:

>Translated_309_residues
MAMIFPAEPLRPEDRFDAWQEVVSSTYGLVASQPLNEAPFDGRLNVRGQGSVTFTRIQSSPLHYRRLQQDRESDHFLLTL
SLCPDALVVQNDRESRQGAGDIVLYDSAQPYACRYPEGDDQIVLTVPRKLLLQHIPSAERLVCRTLDGHSALGRVAAVVL
TEAWNAEGLSDPLSERLNASLLDVLSTAFDSVFGDTDIRRQSHQMQQLQRIKQFLLNNLPDTGLTAENIALATHVSPRTL
NRLFAREGTTAIRWLWQQRLSACHDALLKRHVRRVSDAALNFGFTNLSHFSRAFKNAYGIPPQQLLEPR
>Mature_308_residues
AMIFPAEPLRPEDRFDAWQEVVSSTYGLVASQPLNEAPFDGRLNVRGQGSVTFTRIQSSPLHYRRLQQDRESDHFLLTLS
LCPDALVVQNDRESRQGAGDIVLYDSAQPYACRYPEGDDQIVLTVPRKLLLQHIPSAERLVCRTLDGHSALGRVAAVVLT
EAWNAEGLSDPLSERLNASLLDVLSTAFDSVFGDTDIRRQSHQMQQLQRIKQFLLNNLPDTGLTAENIALATHVSPRTLN
RLFAREGTTAIRWLWQQRLSACHDALLKRHVRRVSDAALNFGFTNLSHFSRAFKNAYGIPPQQLLEPR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=299, Percent_Identity=26.7558528428094, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34793; Mature: 34662

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMIFPAEPLRPEDRFDAWQEVVSSTYGLVASQPLNEAPFDGRLNVRGQGSVTFTRIQSS
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEECCC
PLHYRRLQQDRESDHFLLTLSLCPDALVVQNDRESRQGAGDIVLYDSAQPYACRYPEGDD
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHCCCCCCEEEEECCCCCEEECCCCCC
QIVLTVPRKLLLQHIPSAERLVCRTLDGHSALGRVAAVVLTEAWNAEGLSDPLSERLNAS
EEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLDVLSTAFDSVFGDTDIRRQSHQMQQLQRIKQFLLNNLPDTGLTAENIALATHVSPRTL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCHHHH
NRLFAREGTTAIRWLWQQRLSACHDALLKRHVRRVSDAALNFGFTNLSHFSRAFKNAYGI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PPQQLLEPR
CHHHHCCCC
>Mature Secondary Structure 
AMIFPAEPLRPEDRFDAWQEVVSSTYGLVASQPLNEAPFDGRLNVRGQGSVTFTRIQSS
CEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEECCC
PLHYRRLQQDRESDHFLLTLSLCPDALVVQNDRESRQGAGDIVLYDSAQPYACRYPEGDD
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHCCCCCCEEEEECCCCCEEECCCCCC
QIVLTVPRKLLLQHIPSAERLVCRTLDGHSALGRVAAVVLTEAWNAEGLSDPLSERLNAS
EEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLDVLSTAFDSVFGDTDIRRQSHQMQQLQRIKQFLLNNLPDTGLTAENIALATHVSPRTL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCHHHH
NRLFAREGTTAIRWLWQQRLSACHDALLKRHVRRVSDAALNFGFTNLSHFSRAFKNAYGI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PPQQLLEPR
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]