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The map label for this gene is mmgC [H]

Identifier: 66045416

GI number: 66045416

Start: 2529334

End: 2530497

Strand: Reverse

Name: mmgC [H]

Synonym: Psyr_2176

Alternate gene names: 66045416

Gene position: 2530497-2529334 (Counterclockwise)

Preceding gene: 66045417

Following gene: 66045415

Centisome position: 41.53

GC content: 57.13

Gene sequence:

>1164_bases
ATGACTGACCGTAACTCTGAAGAACTCAATGCCATCCGCGAGGGCGTACGCGCTCTGTGCGCTGAATTCGATGCGGCTTA
CTGGCGCAAAGTCGACGAAGAAAAAGGCTTTCCGGAAACCTTCGTCAAGGCACTGACCGACGCAGGTTGGCTGGCAGCGA
TGATCCCTGTCGAATATGGTGGCTCCGGCCTTGGGTTGGCTGAGGCCTCGGTAATCCTGGAAGAAGTGAACCGCTGCGGC
GGTAATTCCGGCACCGTGCACGGCCAGATGTACAACATGTTCACCCTGCTACGACACGGCAGCGAGGCGCAGAAAAGCTA
CTACCTGCCGAAACTGGCCAGCGGCGAATTGCGCCTGCAATCGATGGGCGTCACCGAACCCACTACCGGTACCGACACTA
CAAAGATAAAGACCACCGCCGTGCGCAAAGGTGACAAGTATGTGATCAACGGGCAGAAGGTCTGGATCTCGCGCGTCCAG
CACTCCGATCTGATGATCTTGCTGGCGCGTACCACGCCTTTGACCGACGTGAAGAAAAAATCCGAAGGTATGTCGATCTT
TCTCGTCGATCTACGCGAGGCCATTGGCAACGGCATGACCGTGCAGCCGATCGCCAACATGGTCAATCACGAAACCAACG
AGCTGTTCTTCGACAACCTGGAAATTCCTGCCGATAGCCTCATCGGCGAGGAAGGCAAAGGTTTCCGCTACATTCTGGAC
GGACTGAACGCCGAGCGCACACTGATCGCAGCCGAATGCATTGGTGACGGTCGCTGGTTTATCGAAAAAGCCAGCGCCTA
TGCGCGTGATCGCGTCGTGTTCGGACGCCCTATCGGGCAGAACCAGGGCGTTCAGTTCCCCATCGCTGAAGCACACATTG
AAATCGAAGCGGCTGACCTGATGCGCTGGCGTGCTTGCGAGGAATACGACAGCGGTATCAACGCCGGGGCCAGTGCCAAT
ATGGCCAAGTACCTGGCGGCGAAAGCCTCGTGGGAAGCCGCCAATGCGTGCTTGCAGACCCACGGCGGTTTTGGTTTTGC
CTGCGAGTACGACGTCGAGCGCAAATTCCGTGAAACCCGTCTGTATCAGGTTGCTCCCATCTCCACCAATCTGATCCTGT
CGTACGTTGCCGAACACCTGCTCGAACTGCCGCGCTCCTTTTAA

Upstream 100 bases:

>100_bases
CTTTCGTGCCGCCTTGGGTTTCAACCCGATCTGATTGCTCTTTGCTCGGCCCCGGTCACGCAGGGCAGTTACCGTGCGTG
ACGCGTTGAGGAGAATAAAA

Downstream 100 bases:

>100_bases
GGAATAAGCGTATAGCCCAGTGCGTCGGCCCAAGCAGACGCGACTGGGGAGCCATGACAAGAGAGATAATAATCATGAGC
CAACCCAAAGGCATCCGTCC

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTDRNSEELNAIREGVRALCAEFDAAYWRKVDEEKGFPETFVKALTDAGWLAAMIPVEYGGSGLGLAEASVILEEVNRCG
GNSGTVHGQMYNMFTLLRHGSEAQKSYYLPKLASGELRLQSMGVTEPTTGTDTTKIKTTAVRKGDKYVINGQKVWISRVQ
HSDLMILLARTTPLTDVKKKSEGMSIFLVDLREAIGNGMTVQPIANMVNHETNELFFDNLEIPADSLIGEEGKGFRYILD
GLNAERTLIAAECIGDGRWFIEKASAYARDRVVFGRPIGQNQGVQFPIAEAHIEIEAADLMRWRACEEYDSGINAGASAN
MAKYLAAKASWEAANACLQTHGGFGFACEYDVERKFRETRLYQVAPISTNLILSYVAEHLLELPRSF

Sequences:

>Translated_387_residues
MTDRNSEELNAIREGVRALCAEFDAAYWRKVDEEKGFPETFVKALTDAGWLAAMIPVEYGGSGLGLAEASVILEEVNRCG
GNSGTVHGQMYNMFTLLRHGSEAQKSYYLPKLASGELRLQSMGVTEPTTGTDTTKIKTTAVRKGDKYVINGQKVWISRVQ
HSDLMILLARTTPLTDVKKKSEGMSIFLVDLREAIGNGMTVQPIANMVNHETNELFFDNLEIPADSLIGEEGKGFRYILD
GLNAERTLIAAECIGDGRWFIEKASAYARDRVVFGRPIGQNQGVQFPIAEAHIEIEAADLMRWRACEEYDSGINAGASAN
MAKYLAAKASWEAANACLQTHGGFGFACEYDVERKFRETRLYQVAPISTNLILSYVAEHLLELPRSF
>Mature_386_residues
TDRNSEELNAIREGVRALCAEFDAAYWRKVDEEKGFPETFVKALTDAGWLAAMIPVEYGGSGLGLAEASVILEEVNRCGG
NSGTVHGQMYNMFTLLRHGSEAQKSYYLPKLASGELRLQSMGVTEPTTGTDTTKIKTTAVRKGDKYVINGQKVWISRVQH
SDLMILLARTTPLTDVKKKSEGMSIFLVDLREAIGNGMTVQPIANMVNHETNELFFDNLEIPADSLIGEEGKGFRYILDG
LNAERTLIAAECIGDGRWFIEKASAYARDRVVFGRPIGQNQGVQFPIAEAHIEIEAADLMRWRACEEYDSGINAGASANM
AKYLAAKASWEAANACLQTHGGFGFACEYDVERKFRETRLYQVAPISTNLILSYVAEHLLELPRSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=28.8713910761155, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4557233, Length=363, Percent_Identity=30.3030303030303, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI226958412, Length=365, Percent_Identity=30.1369863013699, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=30.9090909090909, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=29.7587131367292, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI4501857, Length=335, Percent_Identity=32.5373134328358, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=29.7587131367292, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI76496475, Length=349, Percent_Identity=30.945558739255, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4557235, Length=349, Percent_Identity=30.945558739255, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7656849, Length=361, Percent_Identity=28.808864265928, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI21361497, Length=384, Percent_Identity=26.8229166666667, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI38505218, Length=327, Percent_Identity=27.217125382263, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI48976061, Length=282, Percent_Identity=26.241134751773, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI211971008, Length=282, Percent_Identity=26.241134751773, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7669494, Length=289, Percent_Identity=26.643598615917, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4503943, Length=352, Percent_Identity=25.5681818181818, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=30.2083333333333, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=27.9569892473118, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17534899, Length=340, Percent_Identity=33.8235294117647, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=372, Percent_Identity=31.7204301075269, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=337, Percent_Identity=30.5637982195846, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=28.6472148541114, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=28.4552845528455, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=385, Percent_Identity=29.3506493506493, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=28.0748663101604, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17505929, Length=347, Percent_Identity=30.835734870317, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=30.7432432432432, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17551932, Length=347, Percent_Identity=30.5475504322767, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=320, Percent_Identity=30, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=354, Percent_Identity=28.2485875706215, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=30.1724137931034, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=370, Percent_Identity=25.4054054054054, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=253, Percent_Identity=26.8774703557312, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=257, Percent_Identity=27.2373540856031, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=263, Percent_Identity=26.615969581749, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356377, Length=338, Percent_Identity=30.7692307692308, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.6068601583113, Blast_Score=167, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24646207, Length=352, Percent_Identity=29.2613636363636, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24660351, Length=343, Percent_Identity=30.6122448979592, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355753, Length=345, Percent_Identity=30.1449275362319, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281363737, Length=374, Percent_Identity=27.5401069518717, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI19920834, Length=297, Percent_Identity=28.6195286195286, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42801; Mature: 42670

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRNSEELNAIREGVRALCAEFDAAYWRKVDEEKGFPETFVKALTDAGWLAAMIPVEYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEEEEC
GSGLGLAEASVILEEVNRCGGNSGTVHGQMYNMFTLLRHGSEAQKSYYLPKLASGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEE
SMGVTEPTTGTDTTKIKTTAVRKGDKYVINGQKVWISRVQHSDLMILLARTTPLTDVKKK
ECCCCCCCCCCCCCEEEEEEEECCCEEEECCCEEEEEHHCCCCEEEEEECCCCCHHHHHH
SEGMSIFLVDLREAIGNGMTVQPIANMVNHETNELFFDNLEIPADSLIGEEGKGFRYILD
CCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCCEEEEC
GLNAERTLIAAECIGDGRWFIEKASAYARDRVVFGRPIGQNQGVQFPIAEAHIEIEAADL
CCCCCCEEEEEEHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEHHHEEEEEHHHH
MRWRACEEYDSGINAGASANMAKYLAAKASWEAANACLQTHGGFGFACEYDVERKFRETR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
LYQVAPISTNLILSYVAEHLLELPRSF
CEEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDRNSEELNAIREGVRALCAEFDAAYWRKVDEEKGFPETFVKALTDAGWLAAMIPVEYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEEEEC
GSGLGLAEASVILEEVNRCGGNSGTVHGQMYNMFTLLRHGSEAQKSYYLPKLASGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEE
SMGVTEPTTGTDTTKIKTTAVRKGDKYVINGQKVWISRVQHSDLMILLARTTPLTDVKKK
ECCCCCCCCCCCCCEEEEEEEECCCEEEECCCEEEEEHHCCCCEEEEEECCCCCHHHHHH
SEGMSIFLVDLREAIGNGMTVQPIANMVNHETNELFFDNLEIPADSLIGEEGKGFRYILD
CCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCCEEEEC
GLNAERTLIAAECIGDGRWFIEKASAYARDRVVFGRPIGQNQGVQFPIAEAHIEIEAADL
CCCCCCEEEEEEHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEHHHEEEEEHHHH
MRWRACEEYDSGINAGASANMAKYLAAKASWEAANACLQTHGGFGFACEYDVERKFRETR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
LYQVAPISTNLILSYVAEHLLELPRSF
CEEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]