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The map label for this gene is etfA [H]

Identifier: 66045413

GI number: 66045413

Start: 2526314

End: 2527243

Strand: Reverse

Name: etfA [H]

Synonym: Psyr_2173

Alternate gene names: 66045413

Gene position: 2527243-2526314 (Counterclockwise)

Preceding gene: 66045414

Following gene: 66045412

Centisome position: 41.47

GC content: 60.43

Gene sequence:

>930_bases
ATGACTATCTTGGTTATTGCTGAACACGACAACAAAGTGCTGGCTCCGGCCACCCTGAACACCGTGGCTGCCGCTGCCAA
AATCGGCGGCGACATCCACGTTCTGGTTGCCGGCCAGGGTGCTGGCGCCGTGGCTGAAGCCGCCGCGAAAATCGCAGGCG
TGAGCAAAGTCCTGAACGCTGACAATGCTGCCTACGCGCATCAGCTGCCGGAAAACGTTGCTCCGCTGGTAGCCGAACTG
GGCGCTGGTTACAGCCACATCCTGGCTGCCGCCACTTCCAACGGCAAAAACATCCTGCCGCGCGTTGCCGCCCAGCTGGA
CGTTGACCAGATTTCCGAGATCATCTCGGTAGAAAGCGCTGACACCTTCAAGCGTCCGATCTACGCCGGTAACGCCATCG
CTACTGTGCAATCGACCGCTGCGATCAAAGTGATCACCGTGCGTGCAACCGGTTTCGACCCGGTTGCCGCTGAAGGTGGT
TCGGCTGCTGTTGAAGCGGTTGCTGCTGCTCACAACGCCGGCACTTCCAGCTTCGTCAGCGAAGAGCTGGCCAAGTCCGA
TCGTCCTGAGCTGACCGCTGCCAAGATCGTCGTTTCCGGCGGCCGCGGCATGCAGAACGGCGACAACTTCAAACACCTGT
ACGCCCTGGCCGACAAGCTGGGCGCTGCCGTCGGTGCTTCCCGTGCAGCGGTCGACGCAGGTTTCGTACCGAACGACATG
CAGGTCGGCCAGACCGGCAAGATCGTTGCGCCACAGCTGTACATCGCCGTCGGTATCTCCGGCGCGATCCAGCACCTGGC
CGGCATGAAAGACTCCAAAGTGATCGTTGCGATCAACAAGGACGAAGAAGCACCGATCTTCCAGGTGGCCGATTACGGCC
TGGTGGCGGATCTTTTTGAAGCGATTCCAGAAATGGCCACCCTGGCTTGA

Upstream 100 bases:

>100_bases
CCTGAAAGTCGAAGCGCCGGCTGCACGCAGCGCGGGCATCAAGGTCAAGTCGGTGGCTGAACTGGTCGAGAAACTGAAAA
ACGAAGCGAAGGTAATCTAA

Downstream 100 bases:

>100_bases
TCACTGACCGACTGGAGCAAAGAATATGAGCAACAGTTCCGATTTTTCCGCCTGGATTGGACGACGTCAGGAAAGCCAGG
ACCGGATCAGTTTCACTCTG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAEL
GAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGG
SAAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPEMATLA

Sequences:

>Translated_309_residues
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAEL
GAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGG
SAAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPEMATLA
>Mature_308_residues
TILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAELG
AGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGS
AAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDMQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPEMATLA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=309, Percent_Identity=61.1650485436893, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=62.2710622710623, Blast_Score=340, Evalue=1e-93,
Organism=Escherichia coli, GI1787990, Length=228, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786226, Length=230, Percent_Identity=33.4782608695652, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082157, Length=209, Percent_Identity=33.4928229665072, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=307, Percent_Identity=60.586319218241, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6325261, Length=288, Percent_Identity=45.4861111111111, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=67.1009771986971, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=67.1009771986971, Blast_Score=401, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31262; Mature: 31131

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNA
CEEEEEEECCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
DNAAYAHQLPENVAPLVAELGAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESA
CCCHHHHHCCHHHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCC
DTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGSAAVEAVAAAHNAGTSSFVS
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AIPEMATLA
HHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNA
EEEEEEECCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
DNAAYAHQLPENVAPLVAELGAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESA
CCCHHHHHCCHHHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCC
DTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGSAAVEAVAAAHNAGTSSFVS
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AIPEMATLA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]