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The map label for this gene is bvgA [H]

Identifier: 66045354

GI number: 66045354

Start: 2473029

End: 2473667

Strand: Reverse

Name: bvgA [H]

Synonym: Psyr_2114

Alternate gene names: 66045354

Gene position: 2473667-2473029 (Counterclockwise)

Preceding gene: 66045355

Following gene: 66045353

Centisome position: 40.59

GC content: 51.64

Gene sequence:

>639_bases
ATGGAATGGAATATGAACTCAGTTTTTATCATCGACGACCATCCGGTCATCCGGATGGCGGTAAGAATGCTTCTGGAGAA
CGAAAATTATGAGGTGGTCGGCGAGACCGATAACGGTGTCGACGCCATGCAAATGGTGCGTGAGTGCATGCCCGACCTGA
TCATCCTCGACATCAGCATTCCCAAGCTCGACGGCCTCGAGGTGCTGGCCCGCTTCAATACGATGGGGCTGCCCTCCAAG
ATTCTGGTGCTGACGTCGCAGACCCCCAACCTGTTTGCCATTCGCTGCATGCAATCGGGCGCCTCGGGTTATGTGTGCAA
ACAGGAAGACCTCAGTGAACTGCTCAGTTCGGTGAAAGCGGTATTATCCGGCTACAATTACTTTCCCAGTCAGGCGTTGA
CGTGCGCAGTTCGTGAAGATGGCCAGACCGACGAGCTGGAGCTGTTCAAGTTGGTCAATGACCGTGAACTGATGGTATTG
CAGTTATTTGCCCAGGGCCGTTCCAACAAGGAAATAGCCAAGGGCATGTTTCTCAGTAACAAAACCGTCAGTACTTACAA
AACGCGGCTTATGCAAAAACTGAAAACCAGAACCTTGGTAGAACTTATCGAGATGGCAAAACGCAACGCGCTAGTGTGA

Upstream 100 bases:

>100_bases
ATTTTTGTAGGACTTTTCCTATATATGCCTGCCGAGCAAGTCTCTTTATGTGCCTGCCCGAACATCTGAGCTAAGGTGCG
CGCTTTCTTCACTGCTTGTT

Downstream 100 bases:

>100_bases
GAAAACGGATGTCCAAGCGCTTCAGACAATTATTAATACTGGCCACAAGCCTGTGCATAGGCTGGGGTGCTGAGGCCGGT
GTTCATGCGGCCGATCACTA

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MEWNMNSVFIIDDHPVIRMAVRMLLENENYEVVGETDNGVDAMQMVRECMPDLIILDISIPKLDGLEVLARFNTMGLPSK
ILVLTSQTPNLFAIRCMQSGASGYVCKQEDLSELLSSVKAVLSGYNYFPSQALTCAVREDGQTDELELFKLVNDRELMVL
QLFAQGRSNKEIAKGMFLSNKTVSTYKTRLMQKLKTRTLVELIEMAKRNALV

Sequences:

>Translated_212_residues
MEWNMNSVFIIDDHPVIRMAVRMLLENENYEVVGETDNGVDAMQMVRECMPDLIILDISIPKLDGLEVLARFNTMGLPSK
ILVLTSQTPNLFAIRCMQSGASGYVCKQEDLSELLSSVKAVLSGYNYFPSQALTCAVREDGQTDELELFKLVNDRELMVL
QLFAQGRSNKEIAKGMFLSNKTVSTYKTRLMQKLKTRTLVELIEMAKRNALV
>Mature_212_residues
MEWNMNSVFIIDDHPVIRMAVRMLLENENYEVVGETDNGVDAMQMVRECMPDLIILDISIPKLDGLEVLARFNTMGLPSK
ILVLTSQTPNLFAIRCMQSGASGYVCKQEDLSELLSSVKAVLSGYNYFPSQALTCAVREDGQTDELELFKLVNDRELMVL
QLFAQGRSNKEIAKGMFLSNKTVSTYKTRLMQKLKTRTLVELIEMAKRNALV

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=36.7149758454106, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788712, Length=210, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=32.7014218009479, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=34.5177664974619, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=33, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787473, Length=185, Percent_Identity=30.8108108108108, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788546, Length=207, Percent_Identity=29.951690821256, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23951; Mature: 23951

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWNMNSVFIIDDHPVIRMAVRMLLENENYEVVGETDNGVDAMQMVRECMPDLIILDISI
CCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECC
PKLDGLEVLARFNTMGLPSKILVLTSQTPNLFAIRCMQSGASGYVCKQEDLSELLSSVKA
CCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHH
VLSGYNYFPSQALTCAVREDGQTDELELFKLVNDRELMVLQLFAQGRSNKEIAKGMFLSN
HHCCCCCCCCHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCC
KTVSTYKTRLMQKLKTRTLVELIEMAKRNALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEWNMNSVFIIDDHPVIRMAVRMLLENENYEVVGETDNGVDAMQMVRECMPDLIILDISI
CCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECC
PKLDGLEVLARFNTMGLPSKILVLTSQTPNLFAIRCMQSGASGYVCKQEDLSELLSSVKA
CCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHH
VLSGYNYFPSQALTCAVREDGQTDELELFKLVNDRELMVLQLFAQGRSNKEIAKGMFLSN
HHCCCCCCCCHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCC
KTVSTYKTRLMQKLKTRTLVELIEMAKRNALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]