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The map label for this gene is lgrC [H]

Identifier: 66045197

GI number: 66045197

Start: 2241385

End: 2244795

Strand: Direct

Name: lgrC [H]

Synonym: Psyr_1957

Alternate gene names: 66045197

Gene position: 2241385-2244795 (Clockwise)

Preceding gene: 66045196

Following gene: 66045198

Centisome position: 36.78

GC content: 64.91

Gene sequence:

>3411_bases
ATGAACCCCGAACACGCCCAGAAACTCGCTCGCCGTTTTGTCGAGTTACCCCTTGAAAAACGCCGCCTGTTCCTCGACGG
CATGCGCAAGGAGAACATGGATTTCTCGCTGTTCCCGATCCCTTCCTGTGCCGGGCTGGCCGAGCGTGACGGTCTGTCCT
ATGCCCAGCAACGCATGTGGTTTCTCTGGCAACTGGACCCGCACAGCGCGGCCTACAACCTGCCGATGTCGGTGTGCCTG
AACGGTCCGCTGGAGCTGCCTTTGCTGGAGCGGGCTTTCAGTGCGCTGGTCGAACGACATGAAAGCCTGCGCACCACCTT
CGGCCAGGAGGGCGACCGGGCGTTTCAGCGTGTCGCGCCGCCAGCGCCAGCGAGCATCCGCCTGACCGACCTGAGCGCCT
TGCCGCCCGAGCAGCGCTGGGCCAGTGCGCGTCAGGCCATGGCCGAACAGGCCGCGCAAACCTTCGATCTGCAGCGCGGG
CCGCTGTTCACTGTGCAGGTACTGCGTCTGGCCGAACAGGAGCACCTGCTGCTGCTCAACCTGCACCACATGATCACCGA
TGGCTGGTCGATGAACGTGCTGATCGACGAATGGCTGCGCGGCTACGACGCGCTGCTGGCCGGCAAACCGCTGCCTTTTC
AGCCGCTGCTCGTGCAGTACCGCGATTATGCGGTCTGGCAACGCAGCTGGCTGGAAGCCGGTGAGCAGGAGCGTCAGCTG
GACTACTGGCGCAGCCACCTGGGCGAAGAGCATCCGCTGTTGGAGCTACCCACCGACCGTCCGTATCCGGCCTTGCCCAG
CCACGACGGCGCCCGCCTGGAGCTGGCACTGGAGCCCGAGCTGCTGCGCGACCTGAAAAGCCTCGCGCAGCGCCAAGGCG
TGACCCTGTTCGTGGTGCTGCTGGCGGCCTTCAAAAGCCTGCTGCATCGCTACAGCGGGCAGACCGATATTCGTGTCGGC
GGCCTGATCGCCAACCGCACCCGCAGCGAAACCGAAGGGCTGATCGGCTGCTTCATCAATACTCAGGTACTGCGCAGTGA
AGTGACGGCGCAGACCCGCTTCGTCGATCTGTTGAACATCGTGCGCGACGCCTCGACCGGTGCCCAGGCACATCAGGAGC
TACCGTTCGACGCCATCATCGACGCCCTGCAGCCGGAGCGCAGTCAGAGCCATAACCCTTTATTTCAGGTGATGTTCAAT
CACCAGCCGGTGGTGGCCGACCTGCTCGACAAACAGTTGAGCGGCGGCCTGCGCGTGGCCAATCTGCCTGCCGGGCAACA
GGCATTGGCGCAGCGCTCGCACGCTGCCGCCAGCGACCTGATGCTGGCCACCAGCGGTGAAGGCGAGCAACTGCATGCCG
CCTTCACCTACGCCACCGACATCTTTGACGAGTCGACCATCGCTCGCCTGGCCGGGCACTGGCGCAACCTGTTGGCCTCT
GTCTGTGCCGACCCGCTGCAGACCATCGCCGAGCTGTCGATGCTCTCGGCCGACGAGCGCACGCAACTGCTGGATGTCGA
CAACGCCACCAAAGCCGACACCACAACTCCCGCGCATCGCCAGTTCGAAGCGCAAGTACAACGCACACCGGACGCACTGG
CGCTGATCCTCGCCCGTGAAGGTCAATCGCCGAGCCTGAGCTACACCGAACTGAACCAGCGCAGTAACCGTCTGGCCTGG
CAACTGCGCGAGCAGGGTGTCGGTGCGGACGTGCTGGTCGGCGTGGCGCTGGGCCGCTCGCTGGACATGCCCGTGGCGCT
GCTCGCCGTGCTCAAGGCGGGCGGCGCCTATGTGCCACTGGACCTGAACGCGCCGAGCGAACGCTTGCGTCATGTAGTCG
AGGACAGTGGCGTGAAACTGCTGCTGACCCATAGCGATCAGCTGACCGGGCTGCCTGAACTGGCTGATATTCAATGCCTG
TGCATCGATCGGATGAACAGCGAAACCGCCAGCGTGCAAAACCTCGACGGCCCGATCGATCCGGCCAGTCTGGCCTACGT
GATCTACACCTCGGGGTCGACCGGGCGGCCTAAAGGCGTGGCGATCAGTCATGCGGCGCTGGCCGAATTCGTCACCCTGG
GTGCTGACTACAGTGACCTGCACGAAGGCGACCGGGTCCTGCAATTCGCCACCCACAGCTTCGACGGCTTCGTCGAGCAG
TTCTACCCACCGTTGTGTCGCGGTGCGGCCGTTGTGCTGCGTGACGAACGCCTGTGGGACAGCGCCACCTTCCATCAGGC
CATCGTCGAGCACGGCGTGACCCTCGCCGACTTGCCCGCGGCCTATTGGCTGACGCTGGTTCAGGACTTCGCCGCCAGCC
CGCCCGTGCATTACGGCGCGCTACGCCAGGTGCATGTTGGCGGCGAAGCCATGGCCGTCGAGGGGCTGCGCCTGTGGCAC
AAGGCCGGGCTCGGGCATGTACGCCTGCTCAATACCTATGGCCCGACCGAAGCCACCGTGGTGTCGAGCATCCATGATTG
CAGCACGCTGACCCCGCAGCAGGTGTCCTGGCGCGGCGTGCCGATTGGCCATGCGCTGGCAGGACGACGCCTGTACGTTC
TCGACGATCAAATGAACCTGCTGCCGCAAGGTGCGGTGGGCGAGCTGTACATCGGTGGTCCTGGTCTGGCGCGCGGTTAT
CACGCCCAGCCCGGTCTGAGCGCCGAACGTTTCGTCGCCGATCCGTTTGGCAGCGGTGAGCGCCTGTACCGCAGCGGCGA
CCGCGCCCGACTGCGTGCCGATGGCGCTGTCGAGTACATCGGCCGGGTCGATCATCAAGTGAAGATTCGCGGTTTCCGTA
TCGAGCTGGGCGAGGTCGAATCGCGCCTGCAGCAATGCACGGGCGTGCGCGAGGCCGTGGTGCTGGCCGTCGAACTGGCG
GGCAGCACGCAGTTGGTCGCCTACGCCGTGCCTGACGTTGCCGCCTCCACAGAGGCCGAACAGTTGGCCCTGCGCCAAAG
CATCCGCAGCCAGTTGCAAGCCTTCCTGCCGGATTACATGGTGCCGACGCACATGCTGCTGTTGCCAGAGCTGCCCCTGA
CGCCCAGCGGCAAGCTGGACCGCAAGGCATTGCCGACCCCCGACGCAAGCCAGTTGCAGGCGCGTTATCGGGCGCCGCGC
AGCGAGGTGGAAATCTGCCTGGCGGCCATCTGGCAGGACGTCCTGCACGCACCCCAGGTGGGCCTGGACGATCACTTCTT
CGAACTGGGCGGGCACTCGTTGCTCGCCGCACAAGTCATCGCCCGGATCAAGACGCAGCTGGGCGTCAGCCTGCCGCTGC
GCACCCTGTTTGAAAAACCGCTGCTCAGTGAGCTCGCCGTCGAAGTGGCAGCGCTGACCGAAAACAGCACGGACAACGAC
TGGAGCGACATGGACCAGTTCATGGATTCACTGGAGGAATTCGGCGCATGA

Upstream 100 bases:

>100_bases
CCTCACCCCCCGAGAAACCTTTCTAAATATTTCCTCGCCAATTCGTTCTTGTTGATACGACCCCGCCCGACGGTCAGCCC
CACTCAGCAAGGATCGACCC

Downstream 100 bases:

>100_bases
CCGGGACCACTGCTGCACGCATCGCGAAACGTTTTGTCGGCCTGTCGCTGGAGCAACGCCAGCAGTTCCTCGCCCGGTTG
CGCCAGGAAGGCAAGGATTT

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1136; Mature: 1136

Protein sequence:

>1136_residues
MNPEHAQKLARRFVELPLEKRRLFLDGMRKENMDFSLFPIPSCAGLAERDGLSYAQQRMWFLWQLDPHSAAYNLPMSVCL
NGPLELPLLERAFSALVERHESLRTTFGQEGDRAFQRVAPPAPASIRLTDLSALPPEQRWASARQAMAEQAAQTFDLQRG
PLFTVQVLRLAEQEHLLLLNLHHMITDGWSMNVLIDEWLRGYDALLAGKPLPFQPLLVQYRDYAVWQRSWLEAGEQERQL
DYWRSHLGEEHPLLELPTDRPYPALPSHDGARLELALEPELLRDLKSLAQRQGVTLFVVLLAAFKSLLHRYSGQTDIRVG
GLIANRTRSETEGLIGCFINTQVLRSEVTAQTRFVDLLNIVRDASTGAQAHQELPFDAIIDALQPERSQSHNPLFQVMFN
HQPVVADLLDKQLSGGLRVANLPAGQQALAQRSHAAASDLMLATSGEGEQLHAAFTYATDIFDESTIARLAGHWRNLLAS
VCADPLQTIAELSMLSADERTQLLDVDNATKADTTTPAHRQFEAQVQRTPDALALILAREGQSPSLSYTELNQRSNRLAW
QLREQGVGADVLVGVALGRSLDMPVALLAVLKAGGAYVPLDLNAPSERLRHVVEDSGVKLLLTHSDQLTGLPELADIQCL
CIDRMNSETASVQNLDGPIDPASLAYVIYTSGSTGRPKGVAISHAALAEFVTLGADYSDLHEGDRVLQFATHSFDGFVEQ
FYPPLCRGAAVVLRDERLWDSATFHQAIVEHGVTLADLPAAYWLTLVQDFAASPPVHYGALRQVHVGGEAMAVEGLRLWH
KAGLGHVRLLNTYGPTEATVVSSIHDCSTLTPQQVSWRGVPIGHALAGRRLYVLDDQMNLLPQGAVGELYIGGPGLARGY
HAQPGLSAERFVADPFGSGERLYRSGDRARLRADGAVEYIGRVDHQVKIRGFRIELGEVESRLQQCTGVREAVVLAVELA
GSTQLVAYAVPDVAASTEAEQLALRQSIRSQLQAFLPDYMVPTHMLLLPELPLTPSGKLDRKALPTPDASQLQARYRAPR
SEVEICLAAIWQDVLHAPQVGLDDHFFELGGHSLLAAQVIARIKTQLGVSLPLRTLFEKPLLSELAVEVAALTENSTDND
WSDMDQFMDSLEEFGA

Sequences:

>Translated_1136_residues
MNPEHAQKLARRFVELPLEKRRLFLDGMRKENMDFSLFPIPSCAGLAERDGLSYAQQRMWFLWQLDPHSAAYNLPMSVCL
NGPLELPLLERAFSALVERHESLRTTFGQEGDRAFQRVAPPAPASIRLTDLSALPPEQRWASARQAMAEQAAQTFDLQRG
PLFTVQVLRLAEQEHLLLLNLHHMITDGWSMNVLIDEWLRGYDALLAGKPLPFQPLLVQYRDYAVWQRSWLEAGEQERQL
DYWRSHLGEEHPLLELPTDRPYPALPSHDGARLELALEPELLRDLKSLAQRQGVTLFVVLLAAFKSLLHRYSGQTDIRVG
GLIANRTRSETEGLIGCFINTQVLRSEVTAQTRFVDLLNIVRDASTGAQAHQELPFDAIIDALQPERSQSHNPLFQVMFN
HQPVVADLLDKQLSGGLRVANLPAGQQALAQRSHAAASDLMLATSGEGEQLHAAFTYATDIFDESTIARLAGHWRNLLAS
VCADPLQTIAELSMLSADERTQLLDVDNATKADTTTPAHRQFEAQVQRTPDALALILAREGQSPSLSYTELNQRSNRLAW
QLREQGVGADVLVGVALGRSLDMPVALLAVLKAGGAYVPLDLNAPSERLRHVVEDSGVKLLLTHSDQLTGLPELADIQCL
CIDRMNSETASVQNLDGPIDPASLAYVIYTSGSTGRPKGVAISHAALAEFVTLGADYSDLHEGDRVLQFATHSFDGFVEQ
FYPPLCRGAAVVLRDERLWDSATFHQAIVEHGVTLADLPAAYWLTLVQDFAASPPVHYGALRQVHVGGEAMAVEGLRLWH
KAGLGHVRLLNTYGPTEATVVSSIHDCSTLTPQQVSWRGVPIGHALAGRRLYVLDDQMNLLPQGAVGELYIGGPGLARGY
HAQPGLSAERFVADPFGSGERLYRSGDRARLRADGAVEYIGRVDHQVKIRGFRIELGEVESRLQQCTGVREAVVLAVELA
GSTQLVAYAVPDVAASTEAEQLALRQSIRSQLQAFLPDYMVPTHMLLLPELPLTPSGKLDRKALPTPDASQLQARYRAPR
SEVEICLAAIWQDVLHAPQVGLDDHFFELGGHSLLAAQVIARIKTQLGVSLPLRTLFEKPLLSELAVEVAALTENSTDND
WSDMDQFMDSLEEFGA
>Mature_1136_residues
MNPEHAQKLARRFVELPLEKRRLFLDGMRKENMDFSLFPIPSCAGLAERDGLSYAQQRMWFLWQLDPHSAAYNLPMSVCL
NGPLELPLLERAFSALVERHESLRTTFGQEGDRAFQRVAPPAPASIRLTDLSALPPEQRWASARQAMAEQAAQTFDLQRG
PLFTVQVLRLAEQEHLLLLNLHHMITDGWSMNVLIDEWLRGYDALLAGKPLPFQPLLVQYRDYAVWQRSWLEAGEQERQL
DYWRSHLGEEHPLLELPTDRPYPALPSHDGARLELALEPELLRDLKSLAQRQGVTLFVVLLAAFKSLLHRYSGQTDIRVG
GLIANRTRSETEGLIGCFINTQVLRSEVTAQTRFVDLLNIVRDASTGAQAHQELPFDAIIDALQPERSQSHNPLFQVMFN
HQPVVADLLDKQLSGGLRVANLPAGQQALAQRSHAAASDLMLATSGEGEQLHAAFTYATDIFDESTIARLAGHWRNLLAS
VCADPLQTIAELSMLSADERTQLLDVDNATKADTTTPAHRQFEAQVQRTPDALALILAREGQSPSLSYTELNQRSNRLAW
QLREQGVGADVLVGVALGRSLDMPVALLAVLKAGGAYVPLDLNAPSERLRHVVEDSGVKLLLTHSDQLTGLPELADIQCL
CIDRMNSETASVQNLDGPIDPASLAYVIYTSGSTGRPKGVAISHAALAEFVTLGADYSDLHEGDRVLQFATHSFDGFVEQ
FYPPLCRGAAVVLRDERLWDSATFHQAIVEHGVTLADLPAAYWLTLVQDFAASPPVHYGALRQVHVGGEAMAVEGLRLWH
KAGLGHVRLLNTYGPTEATVVSSIHDCSTLTPQQVSWRGVPIGHALAGRRLYVLDDQMNLLPQGAVGELYIGGPGLARGY
HAQPGLSAERFVADPFGSGERLYRSGDRARLRADGAVEYIGRVDHQVKIRGFRIELGEVESRLQQCTGVREAVVLAVELA
GSTQLVAYAVPDVAASTEAEQLALRQSIRSQLQAFLPDYMVPTHMLLLPELPLTPSGKLDRKALPTPDASQLQARYRAPR
SEVEICLAAIWQDVLHAPQVGLDDHFFELGGHSLLAAQVIARIKTQLGVSLPLRTLFEKPLLSELAVEVAALTENSTDND
WSDMDQFMDSLEEFGA

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=603, Percent_Identity=22.5538971807629, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI28416953, Length=564, Percent_Identity=24.645390070922, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI38505220, Length=365, Percent_Identity=23.5616438356164, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI122937307, Length=530, Percent_Identity=22.4528301886792, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI115511026, Length=540, Percent_Identity=20.3703703703704, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI58082049, Length=520, Percent_Identity=21.3461538461538, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI157311624, Length=523, Percent_Identity=21.7973231357553, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI157311622, Length=523, Percent_Identity=21.7973231357553, Blast_Score=82, Evalue=4e-15,
Organism=Escherichia coli, GI1786801, Length=1093, Percent_Identity=31.1985361390668, Blast_Score=347, Evalue=4e-96,
Organism=Escherichia coli, GI145693145, Length=524, Percent_Identity=24.8091603053435, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786810, Length=520, Percent_Identity=25.3846153846154, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790505, Length=548, Percent_Identity=23.3576642335766, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556356, Length=581, Percent_Identity=27.0223752151463, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17550940, Length=576, Percent_Identity=24.3055555555556, Blast_Score=112, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319591, Length=943, Percent_Identity=24.8144220572641, Blast_Score=228, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6319264, Length=554, Percent_Identity=23.4657039711191, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319699, Length=377, Percent_Identity=22.0159151193634, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648676, Length=541, Percent_Identity=29.9445471349353, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24582852, Length=607, Percent_Identity=25.0411861614498, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648260, Length=527, Percent_Identity=22.3908918406072, Blast_Score=68, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 125251; Mature: 125251

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPEHAQKLARRFVELPLEKRRLFLDGMRKENMDFSLFPIPSCAGLAERDGLSYAQQRMW
CCHHHHHHHHHHHHHCCHHHHHHHHHCHHCCCCCEEEECCCCCCCCHHHCCHHHHHHHEE
FLWQLDPHSAAYNLPMSVCLNGPLELPLLERAFSALVERHESLRTTFGQEGDRAFQRVAP
EEEEECCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PAPASIRLTDLSALPPEQRWASARQAMAEQAAQTFDLQRGPLFTVQVLRLAEQEHLLLLN
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
LHHMITDGWSMNVLIDEWLRGYDALLAGKPLPFQPLLVQYRDYAVWQRSWLEAGEQERQL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
DYWRSHLGEEHPLLELPTDRPYPALPSHDGARLELALEPELLRDLKSLAQRQGVTLFVVL
HHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHH
LAAFKSLLHRYSGQTDIRVGGLIANRTRSETEGLIGCFINTQVLRSEVTAQTRFVDLLNI
HHHHHHHHHHHCCCCCEEECCEEECCCCCHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VRDASTGAQAHQELPFDAIIDALQPERSQSHNPLFQVMFNHQPVVADLLDKQLSGGLRVA
HHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEE
NLPAGQQALAQRSHAAASDLMLATSGEGEQLHAAFTYATDIFDESTIARLAGHWRNLLAS
ECCCCHHHHHHHHHHHHHCEEEEECCCCCEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHH
VCADPLQTIAELSMLSADERTQLLDVDNATKADTTTPAHRQFEAQVQRTPDALALILARE
HHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECC
GQSPSLSYTELNQRSNRLAWQLREQGVGADVLVGVALGRSLDMPVALLAVLKAGGAYVPL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
DLNAPSERLRHVVEDSGVKLLLTHSDQLTGLPELADIQCLCIDRMNSETASVQNLDGPID
ECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCEEEEEECCCCCHHHHHCCCCCCC
PASLAYVIYTSGSTGRPKGVAISHAALAEFVTLGADYSDLHEGDRVLQFATHSFDGFVEQ
CCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
FYPPLCRGAAVVLRDERLWDSATFHQAIVEHGVTLADLPAAYWLTLVQDFAASPPVHYGA
HCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCCCCC
LRQVHVGGEAMAVEGLRLWHKAGLGHVRLLNTYGPTEATVVSSIHDCSTLTPQQVSWRGV
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
PIGHALAGRRLYVLDDQMNLLPQGAVGELYIGGPGLARGYHAQPGLSAERFVADPFGSGE
CCHHHHHCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCH
RLYRSGDRARLRADGAVEYIGRVDHQVKIRGFRIELGEVESRLQQCTGVREAVVLAVELA
HHHHCCCCCEEECCHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHCHHHHHEEEEEEC
GSTQLVAYAVPDVAASTEAEQLALRQSIRSQLQAFLPDYMVPTHMLLLPELPLTPSGKLD
CCCEEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCCCCCC
RKALPTPDASQLQARYRAPRSEVEICLAAIWQDVLHAPQVGLDDHFFELGGHSLLAAQVI
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
ARIKTQLGVSLPLRTLFEKPLLSELAVEVAALTENSTDNDWSDMDQFMDSLEEFGA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPEHAQKLARRFVELPLEKRRLFLDGMRKENMDFSLFPIPSCAGLAERDGLSYAQQRMW
CCHHHHHHHHHHHHHCCHHHHHHHHHCHHCCCCCEEEECCCCCCCCHHHCCHHHHHHHEE
FLWQLDPHSAAYNLPMSVCLNGPLELPLLERAFSALVERHESLRTTFGQEGDRAFQRVAP
EEEEECCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PAPASIRLTDLSALPPEQRWASARQAMAEQAAQTFDLQRGPLFTVQVLRLAEQEHLLLLN
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
LHHMITDGWSMNVLIDEWLRGYDALLAGKPLPFQPLLVQYRDYAVWQRSWLEAGEQERQL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
DYWRSHLGEEHPLLELPTDRPYPALPSHDGARLELALEPELLRDLKSLAQRQGVTLFVVL
HHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHH
LAAFKSLLHRYSGQTDIRVGGLIANRTRSETEGLIGCFINTQVLRSEVTAQTRFVDLLNI
HHHHHHHHHHHCCCCCEEECCEEECCCCCHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VRDASTGAQAHQELPFDAIIDALQPERSQSHNPLFQVMFNHQPVVADLLDKQLSGGLRVA
HHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEE
NLPAGQQALAQRSHAAASDLMLATSGEGEQLHAAFTYATDIFDESTIARLAGHWRNLLAS
ECCCCHHHHHHHHHHHHHCEEEEECCCCCEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHH
VCADPLQTIAELSMLSADERTQLLDVDNATKADTTTPAHRQFEAQVQRTPDALALILARE
HHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECC
GQSPSLSYTELNQRSNRLAWQLREQGVGADVLVGVALGRSLDMPVALLAVLKAGGAYVPL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
DLNAPSERLRHVVEDSGVKLLLTHSDQLTGLPELADIQCLCIDRMNSETASVQNLDGPID
ECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCEEEEEECCCCCHHHHHCCCCCCC
PASLAYVIYTSGSTGRPKGVAISHAALAEFVTLGADYSDLHEGDRVLQFATHSFDGFVEQ
CCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
FYPPLCRGAAVVLRDERLWDSATFHQAIVEHGVTLADLPAAYWLTLVQDFAASPPVHYGA
HCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCCCCC
LRQVHVGGEAMAVEGLRLWHKAGLGHVRLLNTYGPTEATVVSSIHDCSTLTPQQVSWRGV
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
PIGHALAGRRLYVLDDQMNLLPQGAVGELYIGGPGLARGYHAQPGLSAERFVADPFGSGE
CCHHHHHCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCH
RLYRSGDRARLRADGAVEYIGRVDHQVKIRGFRIELGEVESRLQQCTGVREAVVLAVELA
HHHHCCCCCEEECCHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHCHHHHHEEEEEEC
GSTQLVAYAVPDVAASTEAEQLALRQSIRSQLQAFLPDYMVPTHMLLLPELPLTPSGKLD
CCCEEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCCCCCC
RKALPTPDASQLQARYRAPRSEVEICLAAIWQDVLHAPQVGLDDHFFELGGHSLLAAQVI
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
ARIKTQLGVSLPLRTLFEKPLLSELAVEVAALTENSTDNDWSDMDQFMDSLEEFGA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA