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The map label for this gene is resE [H]

Identifier: 66045159

GI number: 66045159

Start: 2191553

End: 2192686

Strand: Direct

Name: resE [H]

Synonym: Psyr_1918

Alternate gene names: 66045159

Gene position: 2191553-2192686 (Clockwise)

Preceding gene: 66045158

Following gene: 66045162

Centisome position: 35.96

GC content: 58.2

Gene sequence:

>1134_bases
ATGGCTATGCGGTTATCAGGCTTCATCCTCGACAACATCGAGCCTATCGTGCGCGAGTGGACCGATTTCGCACGCACCCT
GTCCGCGCTCGGCGAGCCTCTGGATACCACGGAGCTCAGAGACCATGCCGAGCAAATGCTGCGGGCTATCGCCGCTGATC
TGCAAACGGATCAGTCGTTGCAGCAACAGGTCGACAAATCGCAGGGCCACGGTGTGTCAAATGAACAGACCGCAGCGAAA
AGCCATGCGATCACTCGATTGATGTCGGGCTTCACCATCGATCAGGTGGTCTCGGAGTTTCGGGCATTACGGGCGAGCGT
GATCAAACAGTGGATGTCGCGAGAGGCGCTGGACACTCAACAGCAGATCGAAGACATGATCCGTTTCAACGAGGCGATAG
ATCAGGCCCTGGCCGAGTCTATCTCCAGCTATACCAGCGCGATCCAGGCGTCACGCAACATCTTTCTGGGCATTCTCGGG
CACGACTTGCGCACCCCGCTAAGCGCCATACTGCTGGGTGCCGACGTGTTGTTGCGCACCCATGATCTGGGCGCGCGGCC
AACCAAGGTCGCATCGAGGATCTATTCCAGCGTTAAGCGGGCCAACCAGATCGTTGGCGACCTGCTCGACTTCACGCGCT
CACAGATCGGTCCCGGCATCCCGCTGAAAAAGACCGAAGTAGACATGCAACCCATCTGCGCGCGGATTGTTGAAGAGTCG
AGTACGGTCCACCCTGAGGCAGACATTCGTCTGACTTCAGATGAACCGGTCATTGGCCGCTTCGATGGCGATCGCCTGGA
GCAGGTCTTTTCCAACCTCATCGGCAACGCTATACAGCACGGCAATAGCAGCGATCCCGTCGAAGTGACGCTGGCCGTCT
CGGAGAGCGAGCTGCGTTTTACCGTCCACAACACCGGCAGCCCGATTCCCGAGGACGTGCTTCCGTTCATCTTCAACCCG
ATGGACCGCTATTCACCCGAAAAGATGACCGACAACGGACCTTATTCAAGCCTGGGGCTGGGCCTGTTCATCGTCGACAG
GATTGTCGATGCGCACGGCGGGCATATCGAGGTGACGTCGAAAGCGGATCTGGGGACTACGTTTGCGGTTGTTATCCCGT
TGAGTGCGGGGTGA

Upstream 100 bases:

>100_bases
GTGTGAACTTCACTCCATATTGTATCTGTCCGCCTGATCGGGACGGATACTTGGCTCACCCTACGAATCTGCAGTCTGCC
GGGTTCATGTTCAGGTTTGA

Downstream 100 bases:

>100_bases
GGTCGCGTAGCGGCGATAGAGTTGCGAGGCAACTGAAGAGCATTCGGATCAGAGCTGCCTGTCCCTGATAACGCGCCCGT
CATGGCCTGAAAGTCAGCGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MAMRLSGFILDNIEPIVREWTDFARTLSALGEPLDTTELRDHAEQMLRAIAADLQTDQSLQQQVDKSQGHGVSNEQTAAK
SHAITRLMSGFTIDQVVSEFRALRASVIKQWMSREALDTQQQIEDMIRFNEAIDQALAESISSYTSAIQASRNIFLGILG
HDLRTPLSAILLGADVLLRTHDLGARPTKVASRIYSSVKRANQIVGDLLDFTRSQIGPGIPLKKTEVDMQPICARIVEES
STVHPEADIRLTSDEPVIGRFDGDRLEQVFSNLIGNAIQHGNSSDPVEVTLAVSESELRFTVHNTGSPIPEDVLPFIFNP
MDRYSPEKMTDNGPYSSLGLGLFIVDRIVDAHGGHIEVTSKADLGTTFAVVIPLSAG

Sequences:

>Translated_377_residues
MAMRLSGFILDNIEPIVREWTDFARTLSALGEPLDTTELRDHAEQMLRAIAADLQTDQSLQQQVDKSQGHGVSNEQTAAK
SHAITRLMSGFTIDQVVSEFRALRASVIKQWMSREALDTQQQIEDMIRFNEAIDQALAESISSYTSAIQASRNIFLGILG
HDLRTPLSAILLGADVLLRTHDLGARPTKVASRIYSSVKRANQIVGDLLDFTRSQIGPGIPLKKTEVDMQPICARIVEES
STVHPEADIRLTSDEPVIGRFDGDRLEQVFSNLIGNAIQHGNSSDPVEVTLAVSESELRFTVHNTGSPIPEDVLPFIFNP
MDRYSPEKMTDNGPYSSLGLGLFIVDRIVDAHGGHIEVTSKADLGTTFAVVIPLSAG
>Mature_376_residues
AMRLSGFILDNIEPIVREWTDFARTLSALGEPLDTTELRDHAEQMLRAIAADLQTDQSLQQQVDKSQGHGVSNEQTAAKS
HAITRLMSGFTIDQVVSEFRALRASVIKQWMSREALDTQQQIEDMIRFNEAIDQALAESISSYTSAIQASRNIFLGILGH
DLRTPLSAILLGADVLLRTHDLGARPTKVASRIYSSVKRANQIVGDLLDFTRSQIGPGIPLKKTEVDMQPICARIVEESS
TVHPEADIRLTSDEPVIGRFDGDRLEQVFSNLIGNAIQHGNSSDPVEVTLAVSESELRFTVHNTGSPIPEDVLPFIFNPM
DRYSPEKMTDNGPYSSLGLGLFIVDRIVDAHGGHIEVTSKADLGTTFAVVIPLSAG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=31.140350877193, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=30.4878048780488, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=26.978417266187, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=269, Percent_Identity=28.2527881040892, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=26.6375545851528, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=26.7241379310345, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=223, Percent_Identity=22.8699551569507, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=25.764192139738, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41342; Mature: 41211

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMRLSGFILDNIEPIVREWTDFARTLSALGEPLDTTELRDHAEQMLRAIAADLQTDQSL
CCEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
QQQVDKSQGHGVSNEQTAAKSHAITRLMSGFTIDQVVSEFRALRASVIKQWMSREALDTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QQIEDMIRFNEAIDQALAESISSYTSAIQASRNIFLGILGHDLRTPLSAILLGADVLLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HDLGARPTKVASRIYSSVKRANQIVGDLLDFTRSQIGPGIPLKKTEVDMQPICARIVEES
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
STVHPEADIRLTSDEPVIGRFDGDRLEQVFSNLIGNAIQHGNSSDPVEVTLAVSESELRF
CCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
TVHNTGSPIPEDVLPFIFNPMDRYSPEKMTDNGPYSSLGLGLFIVDRIVDAHGGHIEVTS
EECCCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
KADLGTTFAVVIPLSAG
CCCCCCEEEEEEEECCC
>Mature Secondary Structure 
AMRLSGFILDNIEPIVREWTDFARTLSALGEPLDTTELRDHAEQMLRAIAADLQTDQSL
CEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
QQQVDKSQGHGVSNEQTAAKSHAITRLMSGFTIDQVVSEFRALRASVIKQWMSREALDTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QQIEDMIRFNEAIDQALAESISSYTSAIQASRNIFLGILGHDLRTPLSAILLGADVLLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HDLGARPTKVASRIYSSVKRANQIVGDLLDFTRSQIGPGIPLKKTEVDMQPICARIVEES
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
STVHPEADIRLTSDEPVIGRFDGDRLEQVFSNLIGNAIQHGNSSDPVEVTLAVSESELRF
CCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
TVHNTGSPIPEDVLPFIFNPMDRYSPEKMTDNGPYSSLGLGLFIVDRIVDAHGGHIEVTS
EECCCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
KADLGTTFAVVIPLSAG
CCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]