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The map label for this gene is aroP [C]

Identifier: 66045079

GI number: 66045079

Start: 2114781

End: 2116145

Strand: Reverse

Name: aroP [C]

Synonym: Psyr_1835

Alternate gene names: 66045079

Gene position: 2116145-2114781 (Counterclockwise)

Preceding gene: 66045081

Following gene: 66045078

Centisome position: 34.73

GC content: 62.42

Gene sequence:

>1365_bases
ATGAGCACACAACTCAAGCCGACGCTCGGCACGATTCATTTATGGGGGATCGCGGTAGGGCTGGTGATTTCCGGCGAATA
CTTCGGCTGGAGCTACGGCTGGGGCGTTGCGGGTACGCTGGGCTTTTTGGTAACAGCCCTGATGGTTGCCACCATGTACA
CCTGTTTCATTTTCAGTTTTACCGAGCTCACCACCGCCATCCCGCACGCCGGCGGTCCGTTCGCCTACAGCCGTCGTGCC
TTTGGCGAAAAAGGCGGACTGATCGCAGGCATGGCCACCCTGATCGAGTTCGTCTTTGCGCCACCGGCCATTGCCATGGC
GATCGGTGCGTACCTTAATGTGCAATACCCGGGGCTGGACCCCAAGCATGCGGCAGTCGGCGCCTACATCGTCTTCATGG
CGCTCAACATCGTGGGCGTGAAGCTCGCCGCAACCTTCGAGCTGGTGGTGTGCATTCTGGCCGTCGCCGAGTTGCTGGTG
TTCATGGGCGTCGTCGCGCCTGCCTTCAGTTTCAGCAACTTCGCCCTCAACGGCTGGGCCGGTTCGCAGACCTTCGGACC
CGAAGCCATTGCCGGCATGTTCGCTGCCATCCCCTTCGCCATCTGGTTCTTCCTGGCCATCGAAGGCGCTGCAATGGCCG
CCGAAGAAGCCAAGGACCCGAAACGCACCATCCCGAAGGCCTACATCAGTGGCATTCTGACCTTGGTGATACTGGCGATC
GGCGTCATGCTGTTTGCCGGTGGCGTGGGCGACTGGCGCACCCTGGCCAACATCAACGATCCGCTGCCGCAGGCCATGAA
AGCCGTGGTCGGTGACAGTTCCGGCTGGCTGCACATGCTGGTGTGGATCGGCCTGTTCGGTCTGGTCGCCAGCTTCCACG
GGATCATCATGGGTTACTCGCGCCAGTTCTTCGCCCTCGCCCGCGCCGGCTACCTGCCCGCCTCGCTGGCCAGGCTTTCG
CGCTTCCAGACGCCGCACCGGGCAATCATCGCCGGCGGTCTGATCGGCATCGCCGCGATCTACAGCGACGGCCTGATCAA
CCTGAGTGGCATGACGCTGACCGCTGCGATGATCACCATGGCCGTGTTCGGCGCCATCGTCATGTACATCATGAGCATGC
TCAGCCTGTTCAAACTGCGCAAGACCGAGCCTGGCCTGGAGCGCACGTTCCGCGCCCCCGGTTATCCGGTAGTGCCCGGC
ATCGCCCTGGCGCTGGCCGTCGTGTGTCTGGTGGCAATGGCCTGGTTCAACGCATTGATCGGCCTGATTTTCCTCGGCCT
GATGGCCGTCGGCTTCATCTACTTCAGCCTGACCGCCAAATTGCGTGCCGACGCGCCGACCGACGCGATGCTGACCGGGG
AGTAA

Upstream 100 bases:

>100_bases
TAAACGACCCGTTTTGAAGCATCACGACAGTGATCCGTGCACTGGCACGGCCTCTGCAACAGGATGTTTCAACGTTTATC
GAATCCCAGGGAGAGAAACA

Downstream 100 bases:

>100_bases
CTGCCAGGTTCCAAGGGGTTGCGGGCGAATGCTTTCGCACGCAACCCTTCAGGGCGCATACTCTTGAACCATTAGGCAGC
CGTGCTGCTCAAAGCGGTAT

Product: amino acid permease-associated region

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSTQLKPTLGTIHLWGIAVGLVISGEYFGWSYGWGVAGTLGFLVTALMVATMYTCFIFSFTELTTAIPHAGGPFAYSRRA
FGEKGGLIAGMATLIEFVFAPPAIAMAIGAYLNVQYPGLDPKHAAVGAYIVFMALNIVGVKLAATFELVVCILAVAELLV
FMGVVAPAFSFSNFALNGWAGSQTFGPEAIAGMFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPKAYISGILTLVILAI
GVMLFAGGVGDWRTLANINDPLPQAMKAVVGDSSGWLHMLVWIGLFGLVASFHGIIMGYSRQFFALARAGYLPASLARLS
RFQTPHRAIIAGGLIGIAAIYSDGLINLSGMTLTAAMITMAVFGAIVMYIMSMLSLFKLRKTEPGLERTFRAPGYPVVPG
IALALAVVCLVAMAWFNALIGLIFLGLMAVGFIYFSLTAKLRADAPTDAMLTGE

Sequences:

>Translated_454_residues
MSTQLKPTLGTIHLWGIAVGLVISGEYFGWSYGWGVAGTLGFLVTALMVATMYTCFIFSFTELTTAIPHAGGPFAYSRRA
FGEKGGLIAGMATLIEFVFAPPAIAMAIGAYLNVQYPGLDPKHAAVGAYIVFMALNIVGVKLAATFELVVCILAVAELLV
FMGVVAPAFSFSNFALNGWAGSQTFGPEAIAGMFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPKAYISGILTLVILAI
GVMLFAGGVGDWRTLANINDPLPQAMKAVVGDSSGWLHMLVWIGLFGLVASFHGIIMGYSRQFFALARAGYLPASLARLS
RFQTPHRAIIAGGLIGIAAIYSDGLINLSGMTLTAAMITMAVFGAIVMYIMSMLSLFKLRKTEPGLERTFRAPGYPVVPG
IALALAVVCLVAMAWFNALIGLIFLGLMAVGFIYFSLTAKLRADAPTDAMLTGE
>Mature_453_residues
STQLKPTLGTIHLWGIAVGLVISGEYFGWSYGWGVAGTLGFLVTALMVATMYTCFIFSFTELTTAIPHAGGPFAYSRRAF
GEKGGLIAGMATLIEFVFAPPAIAMAIGAYLNVQYPGLDPKHAAVGAYIVFMALNIVGVKLAATFELVVCILAVAELLVF
MGVVAPAFSFSNFALNGWAGSQTFGPEAIAGMFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPKAYISGILTLVILAIG
VMLFAGGVGDWRTLANINDPLPQAMKAVVGDSSGWLHMLVWIGLFGLVASFHGIIMGYSRQFFALARAGYLPASLARLSR
FQTPHRAIIAGGLIGIAAIYSDGLINLSGMTLTAAMITMAVFGAIVMYIMSMLSLFKLRKTEPGLERTFRAPGYPVVPGI
ALALAVVCLVAMAWFNALIGLIFLGLMAVGFIYFSLTAKLRADAPTDAMLTGE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786302, Length=435, Percent_Identity=23.448275862069, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081708, Length=451, Percent_Identity=24.1685144124169, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786789, Length=373, Percent_Identity=21.71581769437, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790653, Length=300, Percent_Identity=22.6666666666667, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786602, Length=417, Percent_Identity=20.3836930455636, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082250, Length=423, Percent_Identity=23.6406619385343, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081915, Length=357, Percent_Identity=21.8487394957983, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=318, Percent_Identity=26.1006289308176, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48069; Mature: 47938

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQLKPTLGTIHLWGIAVGLVISGEYFGWSYGWGVAGTLGFLVTALMVATMYTCFIFSF
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TELTTAIPHAGGPFAYSRRAFGEKGGLIAGMATLIEFVFAPPAIAMAIGAYLNVQYPGLD
HHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCC
PKHAAVGAYIVFMALNIVGVKLAATFELVVCILAVAELLVFMGVVAPAFSFSNFALNGWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GSQTFGPEAIAGMFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPKAYISGILTLVILAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GVMLFAGGVGDWRTLANINDPLPQAMKAVVGDSSGWLHMLVWIGLFGLVASFHGIIMGYS
HHHHHHCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQFFALARAGYLPASLARLSRFQTPHRAIIAGGLIGIAAIYSDGLINLSGMTLTAAMITM
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHH
AVFGAIVMYIMSMLSLFKLRKTEPGLERTFRAPGYPVVPGIALALAVVCLVAMAWFNALI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIFLGLMAVGFIYFSLTAKLRADAPTDAMLTGE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STQLKPTLGTIHLWGIAVGLVISGEYFGWSYGWGVAGTLGFLVTALMVATMYTCFIFSF
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TELTTAIPHAGGPFAYSRRAFGEKGGLIAGMATLIEFVFAPPAIAMAIGAYLNVQYPGLD
HHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCC
PKHAAVGAYIVFMALNIVGVKLAATFELVVCILAVAELLVFMGVVAPAFSFSNFALNGWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GSQTFGPEAIAGMFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPKAYISGILTLVILAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GVMLFAGGVGDWRTLANINDPLPQAMKAVVGDSSGWLHMLVWIGLFGLVASFHGIIMGYS
HHHHHHCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQFFALARAGYLPASLARLSRFQTPHRAIIAGGLIGIAAIYSDGLINLSGMTLTAAMITM
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHH
AVFGAIVMYIMSMLSLFKLRKTEPGLERTFRAPGYPVVPGIALALAVVCLVAMAWFNALI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIFLGLMAVGFIYFSLTAKLRADAPTDAMLTGE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]