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The map label for this gene is hcrC [H]

Identifier: 66045059

GI number: 66045059

Start: 2089883

End: 2091337

Strand: Reverse

Name: hcrC [H]

Synonym: Psyr_1815

Alternate gene names: 66045059

Gene position: 2091337-2089883 (Counterclockwise)

Preceding gene: 66045065

Following gene: 66045058

Centisome position: 34.32

GC content: 60.48

Gene sequence:

>1455_bases
GTGATTCAGTTCCTTTTGAACCAAGAGCTAAAAACCGAGCGCAGCCTGAATCCGAACATGACCGTGCTGACCTACCTGCG
TGAGCAGGCACACAAGCCCGGTACCAAGGAAGGTTGCGCCAGTGGTGACTGCGGTGCCTGCACCGTCGTGGTGGGCGAGT
TGCACAGTGACACCGACGGCGAGCAAACGCTGCGTTATCGCAGCCTCAATTCGTGCCTGACGTTCATGGCGTCGCTGCAC
GGCAAGCAATTGATCAGCGTCGAAGACCTCAAGCATCAGGGGCAGTTGCACAGCGTGCAGAAGGCGATGGTCGAGTGTCA
TGGCTCGCAATGCGGCTTTTGTACCCCCGGCTTTGTGATGTCGCTGTTTGCCCTGCAAAAGAACAGCAGCGAAGCCGATG
CCCATCAGGCCCACGAAGCCCTGGCCGGCAACTTGTGTCGTTGTACCGGTTATCGCCCTATTCTGGCCGCCGCCGAGCAG
TCTTGCGCGCAGCGCCTGCCGGACCAGTTCGATCAGCGCCAGGCGCAAACCGTCGAACGCCTGCGCGCCATCGCCCCGGC
CAGCACCGATGAACTGAATGACGGCGAAAAACGCTGCTTCATTCCGCTGACCGTGGCGGATCTGGCAGACCTCTACGACA
GCCATCCACAGGCGCGCCTGCTGGCCGGCGGTACCGATCTGGCCCTGGAGGTCACGCAGTTTCACAAACAGTTGCCGGTG
ATGATTTACGTCGGACACATCGATGAAATGAAGGGCGTGAAGCGTTTCGATGACCGCCTGGAGATCGGTGCGGCAACCCC
GCTGACCGATTGCTATGCAGCACTCAAGGCCGAATACCCGGACTTTGGCGAGTTACTGCAGCGCTTCGCCTCGTTGCAGA
TCCGCAATCAGGGCACGCTGGGCGGCAACATCGGCAACGCCTCCCCCATCGGCGACTTCCCGCCGCTGCTGATCGCCCTC
GGTGCGCAGATCGTGCTGCGCAAAGGCAACAGTCAACGCACCCTGGCGCTGGAAGACTATTTCATCGACTACAAGGTCAC
GGCCCGCCAGGAAAGCGAGTTCATCGAAAAGATCATCGTGCCCACTGCCTCTTCGCGACAGATTTTCCGCGCCTATAAAG
TCTCCAAACGGCTGGATGACGACATCTCGGCGGTCTGCGCGGCTTTTCGTCTGACCCTGGAAGGCGGCGTCATCCACGAG
GCTCGCGTAGCGTTCGGTGGTATGGCAGCGATTCCCAAGCGTGCAGCGGCCTGCGAACAGGCGCTGATCGGGCAACCATG
GAGCCATGCAACCGTCGAGCGCGCCTGCGCGGCACTGAGCGAGGACTTCACCCCACTCTCGGATTTCCGGGCGAGCAAAG
AATACCGCCTGTTGAGTGCGCAAAACCTGCTGCGCAAGTACTTCATCGAGTTACAGACCCCAGCCGTTCCAACGCGGGTG
ACTGACTATGTCTGA

Upstream 100 bases:

>100_bases
CAATTTCCTGACTCGGAAGTCAGAAACAAATTGACCCAATAAACAGAGCTGATAGATTCATCGACATGTCTGATGACAAT
AAACGTGAGGGCTTTGCGCC

Downstream 100 bases:

>100_bases
GCATTCCTCAAACAGCACCCAGGCGGAGATGCTGGCGGTATTTCAGCAGGGTCTGAACACCGGCGTGGGCCGCAGCGTCA
AGCACGACAGTGCCGACAAA

Product: ferredoxin:molybdopterin dehydrogenase, FAD-binding:[2Fe-2S]-binding:CO dehydrogenase flavoprotein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MIQFLLNQELKTERSLNPNMTVLTYLREQAHKPGTKEGCASGDCGACTVVVGELHSDTDGEQTLRYRSLNSCLTFMASLH
GKQLISVEDLKHQGQLHSVQKAMVECHGSQCGFCTPGFVMSLFALQKNSSEADAHQAHEALAGNLCRCTGYRPILAAAEQ
SCAQRLPDQFDQRQAQTVERLRAIAPASTDELNDGEKRCFIPLTVADLADLYDSHPQARLLAGGTDLALEVTQFHKQLPV
MIYVGHIDEMKGVKRFDDRLEIGAATPLTDCYAALKAEYPDFGELLQRFASLQIRNQGTLGGNIGNASPIGDFPPLLIAL
GAQIVLRKGNSQRTLALEDYFIDYKVTARQESEFIEKIIVPTASSRQIFRAYKVSKRLDDDISAVCAAFRLTLEGGVIHE
ARVAFGGMAAIPKRAAACEQALIGQPWSHATVERACAALSEDFTPLSDFRASKEYRLLSAQNLLRKYFIELQTPAVPTRV
TDYV

Sequences:

>Translated_484_residues
MIQFLLNQELKTERSLNPNMTVLTYLREQAHKPGTKEGCASGDCGACTVVVGELHSDTDGEQTLRYRSLNSCLTFMASLH
GKQLISVEDLKHQGQLHSVQKAMVECHGSQCGFCTPGFVMSLFALQKNSSEADAHQAHEALAGNLCRCTGYRPILAAAEQ
SCAQRLPDQFDQRQAQTVERLRAIAPASTDELNDGEKRCFIPLTVADLADLYDSHPQARLLAGGTDLALEVTQFHKQLPV
MIYVGHIDEMKGVKRFDDRLEIGAATPLTDCYAALKAEYPDFGELLQRFASLQIRNQGTLGGNIGNASPIGDFPPLLIAL
GAQIVLRKGNSQRTLALEDYFIDYKVTARQESEFIEKIIVPTASSRQIFRAYKVSKRLDDDISAVCAAFRLTLEGGVIHE
ARVAFGGMAAIPKRAAACEQALIGQPWSHATVERACAALSEDFTPLSDFRASKEYRLLSAQNLLRKYFIELQTPAVPTRV
TDYV
>Mature_484_residues
MIQFLLNQELKTERSLNPNMTVLTYLREQAHKPGTKEGCASGDCGACTVVVGELHSDTDGEQTLRYRSLNSCLTFMASLH
GKQLISVEDLKHQGQLHSVQKAMVECHGSQCGFCTPGFVMSLFALQKNSSEADAHQAHEALAGNLCRCTGYRPILAAAEQ
SCAQRLPDQFDQRQAQTVERLRAIAPASTDELNDGEKRCFIPLTVADLADLYDSHPQARLLAGGTDLALEVTQFHKQLPV
MIYVGHIDEMKGVKRFDDRLEIGAATPLTDCYAALKAEYPDFGELLQRFASLQIRNQGTLGGNIGNASPIGDFPPLLIAL
GAQIVLRKGNSQRTLALEDYFIDYKVTARQESEFIEKIIVPTASSRQIFRAYKVSKRLDDDISAVCAAFRLTLEGGVIHE
ARVAFGGMAAIPKRAAACEQALIGQPWSHATVERACAALSEDFTPLSDFRASKEYRLLSAQNLLRKYFIELQTPAVPTRV
TDYV

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=490, Percent_Identity=30.4081632653061, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI71773480, Length=530, Percent_Identity=28.3018867924528, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1789231, Length=271, Percent_Identity=27.6752767527675, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786480, Length=180, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789232, Length=140, Percent_Identity=37.8571428571429, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=537, Percent_Identity=29.9813780260708, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=41.6666666666667, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=41.025641025641, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17737937, Length=499, Percent_Identity=32.8657314629259, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24647197, Length=489, Percent_Identity=29.6523517382413, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24647199, Length=491, Percent_Identity=28.3095723014257, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24647201, Length=490, Percent_Identity=27.7551020408163, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24647193, Length=498, Percent_Identity=27.5100401606426, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24647195, Length=481, Percent_Identity=27.2349272349272, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 53257; Mature: 53257

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFLLNQELKTERSLNPNMTVLTYLREQAHKPGTKEGCASGDCGACTVVVGELHSDTDG
CCCHHHCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCH
EQTLRYRSLNSCLTFMASLHGKQLISVEDLKHQGQLHSVQKAMVECHGSQCGFCTPGFVM
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHH
SLFALQKNSSEADAHQAHEALAGNLCRCTGYRPILAAAEQSCAQRLPDQFDQRQAQTVER
HHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LRAIAPASTDELNDGEKRCFIPLTVADLADLYDSHPQARLLAGGTDLALEVTQFHKQLPV
HHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCE
MIYVGHIDEMKGVKRFDDRLEIGAATPLTDCYAALKAEYPDFGELLQRFASLQIRNQGTL
EEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCEECCCCCC
GGNIGNASPIGDFPPLLIALGAQIVLRKGNSQRTLALEDYFIDYKVTARQESEFIEKIIV
CCCCCCCCCCCCCHHHHHHHCCHHEEECCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHC
PTASSRQIFRAYKVSKRLDDDISAVCAAFRLTLEGGVIHEARVAFGGMAAIPKRAAACEQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHH
ALIGQPWSHATVERACAALSEDFTPLSDFRASKEYRLLSAQNLLRKYFIELQTPAVPTRV
HHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
TDYV
CCCC
>Mature Secondary Structure
MIQFLLNQELKTERSLNPNMTVLTYLREQAHKPGTKEGCASGDCGACTVVVGELHSDTDG
CCCHHHCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCH
EQTLRYRSLNSCLTFMASLHGKQLISVEDLKHQGQLHSVQKAMVECHGSQCGFCTPGFVM
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHH
SLFALQKNSSEADAHQAHEALAGNLCRCTGYRPILAAAEQSCAQRLPDQFDQRQAQTVER
HHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LRAIAPASTDELNDGEKRCFIPLTVADLADLYDSHPQARLLAGGTDLALEVTQFHKQLPV
HHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCE
MIYVGHIDEMKGVKRFDDRLEIGAATPLTDCYAALKAEYPDFGELLQRFASLQIRNQGTL
EEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCEECCCCCC
GGNIGNASPIGDFPPLLIALGAQIVLRKGNSQRTLALEDYFIDYKVTARQESEFIEKIIV
CCCCCCCCCCCCCHHHHHHHCCHHEEECCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHC
PTASSRQIFRAYKVSKRLDDDISAVCAAFRLTLEGGVIHEARVAFGGMAAIPKRAAACEQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHH
ALIGQPWSHATVERACAALSEDFTPLSDFRASKEYRLLSAQNLLRKYFIELQTPAVPTRV
HHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
TDYV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]