Click here to switch to the map view.

The map label for this gene is mcp4 [H]

Identifier: 66045021

GI number: 66045021

Start: 2022789

End: 2024420

Strand: Reverse

Name: mcp4 [H]

Synonym: Psyr_1776

Alternate gene names: 66045021

Gene position: 2024420-2022789 (Counterclockwise)

Preceding gene: 66045022

Following gene: 66045020

Centisome position: 33.22

GC content: 59.99

Gene sequence:

>1632_bases
ATGAGTATGCGCAGTTTGTCCATCAGCCGCCGTCTGTGGCTGATTCTTGTCGTTTCAGTACTGATGCTCTTCGTCCTTTC
GGCGACGCTGCTCAGGCAACTGCATAATGACCTGTATCAGGCCAAGGCCGAGAAAACCATGCATGTGGTGCAGACGGCCA
GCGGCATCCTCTCCTTCTATCAAGGGCTTGAAGCCGCCGGCGGCATGACCCGCGAGGCTGCGCAACAGCAAGCCTTGAAA
GAGATAAAGAGCCTGCGTTACAGCCAGAGCGACTACTTCTGGATCAACGACCTGCGCCCGGTGATGATCATGCACCCCAC
CAACGCCAAGCTCGAAGGCCAGGATCTATCGACCATCAAGGACCCGGACGGCTTTGCGGTGTTCAATGAAATGGTCACGC
TGGTCAAAGCCCAGGGTGCCGGGATGGTCAATTATCGCTGGCCCAAGCCCGGTGCCAGCGAGCCGGTGAAAAAGACCTCC
TACGTGCAGCTGTTTCAACCATGGGGCTGGATTCTGGGGTCCGGCGTTTACGTGGATGACGTAGCGGCGGAGTTCAAGAC
CCAACTGTGGAACGCCGGGATGTTCATCGCCGGCATCGTGCTGATCATGGTGTTGCTGCTGGTCACGATCGTGCGCAGCA
TTGTGCGCCCTCTCAGAGCGGCGGTCGGTGCGATGGCCAGCATTGCCAGTGGCGAGAGCGATCTGACCCGCACGCTGGAA
ACCCACGGCAATGATGAAATAACCGAGCTGGGTACGCACTTCAATGCCTTTGTCGCCAAGCTGCGCAATGTCGTCGGTCA
GTTGCAGCACTCGGCTGTGGCGCTGGGCCAGGCCTCGACCGATCTGGGCAGCGACGCCGAACAGGCGCAGAGCCGCAGCG
AGCAACAATCGCAACAGATGGACCTGGTTGCCACTGCGGTCAACGAAGTGACCTACGGCGTGCAGGACGTGGCCAAGAAC
GCTGAACATGCCGCCAGCGAAATGCGCGATGCCGAGTCACAGGCACAGCAGGGTCAAATCAATATCGATAACAGCCTGCG
CCAGATCGAACACCTCTCCAGCACCATAGGTCAGGCCGTGCAAGTGATGCAGAGCCTGGCCAGCGAGAGCACGCAGATCG
GCAGCGTACTGGAAGTGATCAGTTCGATTGCCGAGCAGACCAACCTGCTGGCGCTGAACGCCGCCATCGAGGCAGCGCGT
GCCGGCGAACAGGGCCGCGGCTTTGCCGTAGTGGCCGACGAAGTGCGTCTGCTGGCCCAGCGCACGCAGAAATCGACCGC
AGAAATCCAGTCAATGATCGAACGCCTGCAAAAGCATTCCGATGCAGCGGTCAAGGTGATCGGTGACAGCAGCCGCTCTT
CGCAGTTGACCATCGAGCAGGCCAATCAGGCCGGCCAGAGCCTGACCTCCATCAGTCAGGCGCTGCGCAACCTCAACAGC
CTGAATGCATCGATCGCCAGCGCCACCCTGCAGCAGACGCACGTGGTGGATGACATCAACCAGAACGTCACCCAGGCCGC
GCAACTGTCCCAGAGCACCGCACTGGCCGCCGAACAATCGACTTCGGCCAGTCTGCACCTGCGCGGGTTGAGCGAAGAGT
TGAACACCTTGCTGAAGCAGTTCCGGGTTTAA

Upstream 100 bases:

>100_bases
GTTTGGTCATTACGCGCCGAGATGCTTGAAAGGCCCTGAATCGCGCGCTGCGCGGATCAGAGTCATCAGAAGAAAAAAAA
TAATGCATGGGATGCCGATC

Downstream 100 bases:

>100_bases
ATCTGCATTGTCATTGGGGTGTCACGGAACCTCGTGCGCCTCTTGTTGCCTGAGACCTGCTTATTCAACCGCTCATTAGC
TGCTTATTTAATTGCAGGGG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFYQGLEAAGGMTREAAQQQALK
EIKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIKDPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTS
YVQLFQPWGWILGSGVYVDDVAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLE
THGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQMDLVATAVNEVTYGVQDVAKN
AEHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAVQVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAAR
AGEQGRGFAVVADEVRLLAQRTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNS
LNASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQFRV

Sequences:

>Translated_543_residues
MSMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFYQGLEAAGGMTREAAQQQALK
EIKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIKDPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTS
YVQLFQPWGWILGSGVYVDDVAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLE
THGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQMDLVATAVNEVTYGVQDVAKN
AEHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAVQVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAAR
AGEQGRGFAVVADEVRLLAQRTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNS
LNASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQFRV
>Mature_542_residues
SMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFYQGLEAAGGMTREAAQQQALKE
IKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIKDPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTSY
VQLFQPWGWILGSGVYVDDVAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLET
HGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQMDLVATAVNEVTYGVQDVAKNA
EHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAVQVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRLLAQRTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNSL
NASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQFRV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=30.9859154929577, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI2367378, Length=390, Percent_Identity=29.4871794871795, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=30.3370786516854, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1788195, Length=337, Percent_Identity=29.673590504451, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=347, Percent_Identity=27.9538904899135, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58886; Mature: 58754

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLEAAGGMTREAAQQQALKEIKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIK
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCC
DPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTSYVQLFQPWGWILGSGVYVDD
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
VAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
THGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DLVATAVNEVTYGVQDVAKNAEHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
RTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LNASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
FRV
HCC
>Mature Secondary Structure 
SMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLEAAGGMTREAAQQQALKEIKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIK
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCC
DPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTSYVQLFQPWGWILGSGVYVDD
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
VAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
THGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DLVATAVNEVTYGVQDVAKNAEHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
RTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LNASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
FRV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]