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The map label for this gene is dnaQ [H]

Identifier: 66045009

GI number: 66045009

Start: 2005215

End: 2005994

Strand: Direct

Name: dnaQ [H]

Synonym: Psyr_1764

Alternate gene names: 66045009

Gene position: 2005215-2005994 (Clockwise)

Preceding gene: 66045008

Following gene: 66045010

Centisome position: 32.91

GC content: 58.85

Gene sequence:

>780_bases
ATGGCATTGCAAAACCTGGATAACAGATCGATCGTCCTCGATACCGAAACCACCGGTATGCCGGTGACGGATGGTCACCG
CATCATCGAGATCGGTTGTGTCGAGTTGATCGGTCGTCGCCTGACCGGGCGGCATTTTCACGTTTACCTGCAACCTGATC
GCGAAAGTGACGAAGGCGCGATCGGTGTTCACGGTATCACCAACGAATTTCTGGTCGGCAAGCCGCGGTTTGCCGAAGTC
GCCGATGAATTCTTCGAGTTCATCAAGGGCGCGCAGCTGATCATTCACAACGCAGCGTTCGACGTTGGCTTCATCAACAA
CGAATTTGCCTTGATGGGTTCGCAGGACAGGGCTGATATCACCCAGCACTGTTCGATTCTCGATACCCTGATGATGGCGC
GAGAGCGCCACCCGGGTCAGCGCAACAGCCTGGATGCACTGTGCAAGCGCTATGGCGTCGACAACTCGGGCCGTGAGTTG
CACGGCGCATTGCTCGACTCCGAGATTCTGGCTGACGTCTACCTGGCGATGACCGGCGGGCAGACCAGCCTGTCGCTGGC
CGGCAATGCTTCCGATGGCAATGGTTCGGGCGAAGGCTCCGGCAACCGTGGCAGCGAAATTCGCCGCCTGCCGGCCGATC
GCAAGCCTTGCCGCATCATTCGCGCTTCTGAAAGTGAACTGGCCGAGCACGAAGTGCGTATGAGCACCATCGCCAAGGCT
TGCGGTGCTCCTCCGCTCTGGGTACAGATGCTGGAAGCCGGAGCACCGGCATCTTCCTGA

Upstream 100 bases:

>100_bases
GCGTCGACGAAGTGCGCGGCATCCGGCACGGCTAGACGCGCACGGGCTTGCAACGGCCGCTGCGTGCTAGAATCGCGGCC
TGTACATGAGGCAACAGTCA

Downstream 100 bases:

>100_bases
CAGCAAGCGGCAAAGGTGGACTGAACGTGGCACATCCTGCTTTGAGCATTCGGGTTGCAGACGAATGCTTCGAGGACTAC
ATCCTCAATAGCGAATTCAC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MALQNLDNRSIVLDTETTGMPVTDGHRIIEIGCVELIGRRLTGRHFHVYLQPDRESDEGAIGVHGITNEFLVGKPRFAEV
ADEFFEFIKGAQLIIHNAAFDVGFINNEFALMGSQDRADITQHCSILDTLMMARERHPGQRNSLDALCKRYGVDNSGREL
HGALLDSEILADVYLAMTGGQTSLSLAGNASDGNGSGEGSGNRGSEIRRLPADRKPCRIIRASESELAEHEVRMSTIAKA
CGAPPLWVQMLEAGAPASS

Sequences:

>Translated_259_residues
MALQNLDNRSIVLDTETTGMPVTDGHRIIEIGCVELIGRRLTGRHFHVYLQPDRESDEGAIGVHGITNEFLVGKPRFAEV
ADEFFEFIKGAQLIIHNAAFDVGFINNEFALMGSQDRADITQHCSILDTLMMARERHPGQRNSLDALCKRYGVDNSGREL
HGALLDSEILADVYLAMTGGQTSLSLAGNASDGNGSGEGSGNRGSEIRRLPADRKPCRIIRASESELAEHEVRMSTIAKA
CGAPPLWVQMLEAGAPASS
>Mature_258_residues
ALQNLDNRSIVLDTETTGMPVTDGHRIIEIGCVELIGRRLTGRHFHVYLQPDRESDEGAIGVHGITNEFLVGKPRFAEVA
DEFFEFIKGAQLIIHNAAFDVGFINNEFALMGSQDRADITQHCSILDTLMMARERHPGQRNSLDALCKRYGVDNSGRELH
GALLDSEILADVYLAMTGGQTSLSLAGNASDGNGSGEGSGNRGSEIRRLPADRKPCRIIRASESELAEHEVRMSTIAKAC
GAPPLWVQMLEAGAPASS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=244, Percent_Identity=52.4590163934426, Blast_Score=257, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28100; Mature: 27969

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQNLDNRSIVLDTETTGMPVTDGHRIIEIGCVELIGRRLTGRHFHVYLQPDRESDEGA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCC
IGVHGITNEFLVGKPRFAEVADEFFEFIKGAQLIIHNAAFDVGFINNEFALMGSQDRADI
EEECCCCCCCEECCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCEEEECCCCHHHH
TQHCSILDTLMMARERHPGQRNSLDALCKRYGVDNSGRELHGALLDSEILADVYLAMTGG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECC
QTSLSLAGNASDGNGSGEGSGNRGSEIRRLPADRKPCRIIRASESELAEHEVRMSTIAKA
CEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
CGAPPLWVQMLEAGAPASS
HCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALQNLDNRSIVLDTETTGMPVTDGHRIIEIGCVELIGRRLTGRHFHVYLQPDRESDEGA
CCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCC
IGVHGITNEFLVGKPRFAEVADEFFEFIKGAQLIIHNAAFDVGFINNEFALMGSQDRADI
EEECCCCCCCEECCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCEEEECCCCHHHH
TQHCSILDTLMMARERHPGQRNSLDALCKRYGVDNSGRELHGALLDSEILADVYLAMTGG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECC
QTSLSLAGNASDGNGSGEGSGNRGSEIRRLPADRKPCRIIRASESELAEHEVRMSTIAKA
CEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
CGAPPLWVQMLEAGAPASS
HCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]