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The map label for this gene is ppiD [H]

Identifier: 66044996

GI number: 66044996

Start: 1990043

End: 1991926

Strand: Direct

Name: ppiD [H]

Synonym: Psyr_1751

Alternate gene names: 66044996

Gene position: 1990043-1991926 (Clockwise)

Preceding gene: 66044995

Following gene: 66044998

Centisome position: 32.66

GC content: 58.01

Gene sequence:

>1884_bases
ATGCTGCAGAATATCAGGGACAATTCACAAGGCTGGATTGCCAAGACAATTATCGGACTCATCATCGCCTTGATGGCCTT
CACCGGCATCGAAGCGATGTTTACCGCTACCAGCAACAAACAGAACGCAGCTGAAGTCAACGGCGAGGACATCTCTCAGA
ATGAGTTGAGCCAGGCCGTGGACATGCAGCGCCGTCAGTTGGCTCAACAGCTCTCGCAACAGCTGGGCAAGGATTTCGAT
CCGGCCATGCTGGATGAGAAACTGTTGCGCGAATCAGCCCTCAAAGGCCTGATCGACCGCAAGCTGCTGCTGCAAGGCGC
GGCGGATGCCAGGTTCTCGTTTTCCGACGCGGCACTGGATCAGCAGCTTTTGCAGACGCCTGAGTTTCAGGTGGATGGCA
AATTCAACGCAGACCGTTTCGATCAGGTGATTCGCCAGCTAGGCTACAGCCGTCTGCAGTTCCGCCAGATGCTGGGTCAG
GAAATGCTCATCGGTCAGGTGCGTGCTGGTGTTGCCGGCAGCGCCTTTGTAACCGACGCACAGGTTGAAGCCTTTGCACG
CCTCGAAAAGCAGACCCGTGATTTCGCTTCGCTGACCCTGCCTGCCGATACCTCGGCGGTCAAAGTGACCGATGACGAAG
TCAAGGCTCACTACGACGAGCATGCCAAGGAGTTCATGAGCCCTGAGCAGGTCGTACTCGACTACATCGAATTGAAGAAG
TCGTCCTTCTTCGACAAGGTGCAGGTCAAGGACGAGGACTTGCAGGCGGCTTATCAGAAGGAAATCGCCAATCTGTCCGA
ACAGCGTCGTGCGGCACACATCCTGATCGAAGTGAACGACAAGCTGAATGACGAGCAGGCCAAGGCGAAGATTGAAGAAA
TTCAGCAGCGTCTGGCCAAGGGTGAGGATTTCGCGGCACTGGCCAAGGAATACTCGCAGGACCCTGGTTCGTCGAACAAG
GGCGGTGATCTGGGCTACGCAGGCAAGGGTGTCTATGACCCGGCTTTCGAAGAGGCGCTGTATGCCTTGAACAAGGACCA
GGTTTCGCAGCCGGTGCGCACCGACTTCGGCTGGCACCTGATCAAGCTGCTGGGCGTTGAAGCACCTTCGGTGCCGAGCT
TTGCCAGTCTGAAAGGCAAGCTGACCAACGATTTGAAATCGCAGCTGGTCGAGCAGAAGTTTGTCGAAGTGACCAAGCAA
CTGGAAGACTCGGCGTTCGAATCGTCCGACCTGTCCCAGCCGGCACAGGACCTGGGCCTGAAGGTTCAGACCACTGCACC
GTTCGGTCGTGAAGGCGGCGAAGGCCTGACGGCCAACCGTGCGGTCATCCAGGCGGCATTCAGCCCTGAAGTGTTGGAAG
AGGGCGCCAACAGCAATACGCTGGAGCTGGATCCGGAAACCGTTGTGGTGGTGCGCTCCAAAGAGCACCTGCAGCCGCAG
CAGTTGCCACTTGAGAGCGTTGCCAGCTCGATTCGCGCTCAACTGGTCAAGGAACATGCTTCGGCCGCTGCCAAGGCCAA
GGGCGAGGCGCTGCTGGCCGGTCTGCGTGACGGCAAGATCCCGTTGGCTGCCAAGCAGGAAGGTCGTGACTGGAAGGTGA
TGGAAGCGGTCACGCGCAGTCAGGAAGGGGTTGACCCTCAAGTGCTGCAGACGCTGTTCCGCATGCCCAAGCCGACAGGT
AAGGACAAGCCGGAATTCGCCAGCATCACTGCTTCGGATGGCAGCTTCGTGATCGTCCGTCTCAATGGCGTCAATCAGGC
GGCTGCACCGACTGACGCCGAGAAGGCGCAATACCGTCGCTTCCTCTCCTCCCGCGAGGGGCAACAGGATTTCGCGGCGT
ACCGTGCACAGTTGGAAAGCAAGGCGAAGATCGAGAAGTTCTAA

Upstream 100 bases:

>100_bases
CAGTTACGAGAAGGCGCATCCTCGGATGCGCCTTTCTTCTATCCGCTTTCTACCCACGCTCCGCGGTTGGTTAGTCAGTA
CAACCGTTTTGGGGGACGCA

Downstream 100 bases:

>100_bases
TCTCGAAACGCGCAAACAAAGAAGGCCGCTCATTGAGCGGCCTTTTTTTTGGATGGCGGTGGGGCCAGTTACGTACCTGC
GTCAGGGTAAGTCATGACTC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAVDMQRRQLAQQLSQQLGKDFD
PAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALDQQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQ
EMLIGQVRAGVAGSAFVTDAQVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAKGEDFAALAKEYSQDPGSSNK
GGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHLIKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQ
LEDSAFESSDLSQPAQDLGLKVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRSQEGVDPQVLQTLFRMPKPTG
KDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRRFLSSREGQQDFAAYRAQLESKAKIEKF

Sequences:

>Translated_627_residues
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAVDMQRRQLAQQLSQQLGKDFD
PAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALDQQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQ
EMLIGQVRAGVAGSAFVTDAQVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAKGEDFAALAKEYSQDPGSSNK
GGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHLIKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQ
LEDSAFESSDLSQPAQDLGLKVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRSQEGVDPQVLQTLFRMPKPTG
KDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRRFLSSREGQQDFAAYRAQLESKAKIEKF
>Mature_627_residues
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAVDMQRRQLAQQLSQQLGKDFD
PAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALDQQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQ
EMLIGQVRAGVAGSAFVTDAQVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAKGEDFAALAKEYSQDPGSSNK
GGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHLIKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQ
LEDSAFESSDLSQPAQDLGLKVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRSQEGVDPQVLQTLFRMPKPTG
KDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRRFLSSREGQQDFAAYRAQLESKAKIEKF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=635, Percent_Identity=29.1338582677165, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1786238, Length=330, Percent_Identity=30.3030303030303, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69087; Mature: 69087

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
DMQRRQLAQQLSQQLGKDFDPAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
QQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQEMLIGQVRAGVAGSAFVTDA
HHHHCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
HHHHHHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHC
GEDFAALAKEYSQDPGSSNKGGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHL
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHCCCHHHHHHHHH
IKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQLEDSAFESSDLSQPAQDLGL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCE
KVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
EEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCEEEECCCEEEEECCHHHCCHH
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
QEGVDPQVLQTLFRMPKPTGKDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRR
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHH
FLSSREGQQDFAAYRAQLESKAKIEKF
HHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
DMQRRQLAQQLSQQLGKDFDPAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
QQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQEMLIGQVRAGVAGSAFVTDA
HHHHCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
HHHHHHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHC
GEDFAALAKEYSQDPGSSNKGGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHL
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHCCCHHHHHHHHH
IKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQLEDSAFESSDLSQPAQDLGL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCE
KVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
EEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCEEEECCCEEEEECCHHHCCHH
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
QEGVDPQVLQTLFRMPKPTGKDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRR
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHH
FLSSREGQQDFAAYRAQLESKAKIEKF
HHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]