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The map label for this gene is ttuB [H]

Identifier: 66044954

GI number: 66044954

Start: 1934834

End: 1936147

Strand: Direct

Name: ttuB [H]

Synonym: Psyr_1709

Alternate gene names: 66044954

Gene position: 1934834-1936147 (Clockwise)

Preceding gene: 66044951

Following gene: 66044955

Centisome position: 31.75

GC content: 61.34

Gene sequence:

>1314_bases
ATGAGCCAGGAACTGCGGCTTATACGCCGCATCACGTTCAAACTGATTCCTTTCCTCATCCTGCTGTACCTGATCGCTTA
TGTAGACCGCTCTGCCGTGGGCTTTGCCAAGCTGCACATGGGCGCGGACATCGGTATCGGCGACGCCGCCTACGGGCTGG
GTGCCGGGCTGTTCTTTATCGGTTACTTCCTGCTGGAGATCCCCAGCAACCTGATGCTCGAGCGTTTCGGCGCACGTCGC
TGGTTCGCGCGGATCATGATCACCTGGGGCGCGATCACCATCGGCATGGCCTTCGTCCAGGGGCCGCACAGCTTCTATGT
GATGAGGTTTTTGCTGGGCGCTGCCGAGGCGGGCTTCTTTCCCGGTGTGCTGTACTACATCACCCAGTGGTTTCCGGTGC
GCCATCGCGGCAAGATCCTTGGCCTTTTCATCCTCTCGCAACCCATCGCCATGATGATCACCGGGCCCGTGTCCGGCGGT
TTGCTGGGCATGGACGGCATACTCGGCCTGCATGGCTGGCAATGGCTGTTCATCGTCATCGGCACGCCGGCGATTCTGCT
GACCTGGCCGGTGCTGCGCTGGTTGCCGGATGGTCCGCAGCAGGTCAAATGGATGGACCAGGCCGAGAAGGACTGGCTGA
CCGGTGAGCTGAAAAAGGACCTTGAAGAGTACGGCCAGACTCGCCACGGCAATCCGTTGCATGCCTTGAAAGACAAACGC
GTGCTGTTGCTGGCGCTGTTCTACCTGCCGGTGACCTTGAGCATCTACGGTCTGGGCCTGTGGCTGCCGACGCTGATCAA
ACAGTTTGGCGGCAGTGACCTGACCACCGGCTTCGTGTCATCGGTGCCTTACATTTTCGGCATCATCGGCCTGCTGATCG
TGCCGCGCAGCTCTGACCGTCTCAACGACCGTTACGGGCATCTGGCCGTGCTTTATGTGCTGGGCGCCATCGGCCTGTTC
TGCAGTGCCTGGCTGACCATGCCGGTGGCGCAGCTGGCTGCATTGTGCGTCGTGGCGTTCGCGCTGTTTTCCTGCACGGC
GGTGTTCTGGACCTTGCCGGGGCGGTTCTTCGCCGGTGCCAGTGCCGCAGCCGGTATCGCGCTGATCAATTCGGTCGGCA
ATTTGGGCGGCTACATCGGTCCGTTCGTGATCGGCGCGTTGAAGGAAATCACCGGCAGTCTGGCATCAGGCCTGTATTTC
CTGTCGGGCGTCATGGTCTTCGGGCTGCTGCTGACCGGCATCGTTTATCACGTGCTGGAGCGCAAGCATGCGCTGCCAGC
GTCCGACTTCGCGGCGAGTGCCAGGGCGAGATAG

Upstream 100 bases:

>100_bases
GACGAGGGATCATCCTGGCGCATGTGCAGTGTTATTCAGCCCCCAGGCACAGAGGCGATCCCCGCAGGTTCCATAACAAA
AACAATGGGAGACCGCCTAC

Downstream 100 bases:

>100_bases
GTTTTCAGCGGCCCATTATCTGGAAGGAGAATTTCATGCGGTTAGTACAGTTTGAATTGAGCGACGGTCAGCGCCGGGTC
GGGCTGGTCGATGGTGATCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSQELRLIRRITFKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLLEIPSNLMLERFGARR
WFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGG
LLGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLEEYGQTRHGNPLHALKDKR
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFVSSVPYIFGIIGLLIVPRSSDRLNDRYGHLAVLYVLGAIGLF
CSAWLTMPVAQLAALCVVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEITGSLASGLYF
LSGVMVFGLLLTGIVYHVLERKHALPASDFAASARAR

Sequences:

>Translated_437_residues
MSQELRLIRRITFKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLLEIPSNLMLERFGARR
WFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGG
LLGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLEEYGQTRHGNPLHALKDKR
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFVSSVPYIFGIIGLLIVPRSSDRLNDRYGHLAVLYVLGAIGLF
CSAWLTMPVAQLAALCVVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEITGSLASGLYF
LSGVMVFGLLLTGIVYHVLERKHALPASDFAASARAR
>Mature_436_residues
SQELRLIRRITFKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLLEIPSNLMLERFGARRW
FARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGL
LGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLEEYGQTRHGNPLHALKDKRV
LLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFVSSVPYIFGIIGLLIVPRSSDRLNDRYGHLAVLYVLGAIGLFC
SAWLTMPVAQLAALCVVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEITGSLASGLYFL
SGVMVFGLLLTGIVYHVLERKHALPASDFAASARAR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=407, Percent_Identity=36.3636363636364, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1789152, Length=437, Percent_Identity=24.2562929061785, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082320, Length=432, Percent_Identity=25.462962962963, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI2367379, Length=420, Percent_Identity=22.8571428571429, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789515, Length=308, Percent_Identity=25.974025974026, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322025, Length=183, Percent_Identity=26.775956284153, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=311, Percent_Identity=22.1864951768489, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322612, Length=285, Percent_Identity=21.4035087719298, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=344, Percent_Identity=21.5116279069767, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47858; Mature: 47726

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQELRLIRRITFKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GYFLLEIPSNLMLERFGARRWFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGLLGMDGILGLHGWQWLFIVI
HHHHHHHHHHCCCCCCCCEEEHHHHHCCHHEEEECCCCCCCCCCCHHHHCCCHHEEEEEE
GTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLEEYGQTRHGNPLHALKDKR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCH
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFVSSVPYIFGIIGLLIVPRSSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
LNDRYGHLAVLYVLGAIGLFCSAWLTMPVAQLAALCVVAFALFSCTAVFWTLPGRFFAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
SAAAGIALINSVGNLGGYIGPFVIGALKEITGSLASGLYFLSGVMVFGLLLTGIVYHVLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHALPASDFAASARAR
HHCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SQELRLIRRITFKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GYFLLEIPSNLMLERFGARRWFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGLLGMDGILGLHGWQWLFIVI
HHHHHHHHHHCCCCCCCCEEEHHHHHCCHHEEEECCCCCCCCCCCHHHHCCCHHEEEEEE
GTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLEEYGQTRHGNPLHALKDKR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCH
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFVSSVPYIFGIIGLLIVPRSSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
LNDRYGHLAVLYVLGAIGLFCSAWLTMPVAQLAALCVVAFALFSCTAVFWTLPGRFFAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
SAAAGIALINSVGNLGGYIGPFVIGALKEITGSLASGLYFLSGVMVFGLLLTGIVYHVLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHALPASDFAASARAR
HHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]