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The map label for this gene is grsB [H]

Identifier: 66044949

GI number: 66044949

Start: 1914095

End: 1918063

Strand: Direct

Name: grsB [H]

Synonym: Psyr_1704

Alternate gene names: 66044949

Gene position: 1914095-1918063 (Clockwise)

Preceding gene: 66044947

Following gene: 66044950

Centisome position: 31.41

GC content: 57.09

Gene sequence:

>3969_bases
ATGAACAGTTTTGAGAAAAATAATACCGCACCGTCACGCTCTCAAGATCTCGCTATGCGGGCCGGCGCACAGCATATAAC
CGGTACTGAAGGGCCACTCTCCATGTCTCAGGAGCAAGCCTGGTTTCTTGAGACGTTAGTACCAGAGAGTATTGCTTATA
ACTTTCAGGCCATGCTGAACATTCGCGGCAACCTTGATATCAACGTGCTTGAACGTGCGCTGAACAGGGTGGTTGAACGC
CATCAGTCACTGTCCACTGTTTTTGATGAGGTTGACGGAGAACCACGGCAAACTATCCAGGACGCCTGGTCCGTGAACAT
TCCGATCGTTGACCTGTCTGCCAGCAGTGAAGCGGTACGGCAGACCTACATGAATTCTATTGTGAAAGCTGAAATTGCCC
AGAAGATCGAAGTGGCGAAACTTCCGCTGATTCGCTGGGTACTGTTCAAATTCAGCGATCAGTTCCACGTATTGCTGCAT
ATCGAACACCACCTCATTCATGACGGCTGGTCATTCCGGCTGTTTCTCAAAGAGCTGAATCATTTTTACAATGAAGAAAA
GGGCCGCGCGAATCAGGAGCCCCTTGAGCCGGTGATCCAGTTCATCGATTACTGCCAATGGGAGCGCGACTGGCTGGATT
CGGCTGAAGGCCGTCAAGGCCGAGACTTCTGGTACGGACGTCTTGAAACCTGGCCGGCCTACACGCATTCGCCGTTTCCG
GCAGAGAAGGACGCGCAAGCCGCATTGGATTTTGTCGGAAGTTCGGTGTCGGTGCCGTTGCCGGGTAAGTTGATCAGCGC
ACTGCAGGCGTATGGGTCGGAAAATAAATCCACCCTGTTCGAGACCATGTTTTCGCTGTTTGCCTGCGTGGTAGCGGCGC
GTTCGGGTCAGACGCAACAGCTGATAGGCACCGCCGTCGCCAACCGTGACTTGCCGGGCATCGAAAACACCATCGGTATG
CTGGTCAACATGTTGCCGCTGCGCATCGACATTGATGCGAATACGTCCTGGGCGCCTCTACTGGCAGCCGTGAAAGAAGA
AATCCGCACGGCTTGCCTGCAGTCGCATGTACCGTTTTCAACAATGGTTGCCGATCTGAGTCCGGATCGTGTCACTCAGC
AATTGCCGTACATCCAGGTTGCTTTCAGCTTTCATAACTCCATGTCCCGCACCCTGGACTTTGCGGACATTGATGTCGAG
GTGGTGGAAGGGCTGGCAAACGGTTCTGCGAAATTCGACCTCAACGTCATTTGCGTTTTCGATGACGAAGTGAACCCGGC
CGCTGGTGGTCGCTTCATGCTTGAGTACTCCACCGCTGTCGCCAAAGAAGCAGATGTCAGAGCGCTGATGGCCGATTTTC
TTCACCTGGCTGGCGCCTGGCTCGAGCAACCTGCAGAAAGTCTCGCCAATGTACGCAAGTCTGCTGTGCTGGCCGCGCCG
TCAGGCAGTTCTTCTGTCAATCCTGGTATGGAATTCTGGAAACAATCACTCGACCTCGAAGCTTCGGGGCTTCTGCCTGA
CCATGCGCTTAATCGCGCAGTCAGCGGGCCGCTTGCGCGTCATGAAATCCCTCTTCCGGATGAAAGCCTTGCGCGCCTGT
TTCAAGCGTGTGAGCAGCGCAACATTGAACCTGAAGCAGCGCTTTTTTCTCTCTATGCCGTGACCATGGCTCGTTATGGC
GGGCATCAAACCGTCGTGGCCGGTCTGGGTACTGCTGCCGATGGACAGCGTCTGGCCATACCGTTGCCACTCAAGTTGAC
GCTCGCTGCGCATGACACGTTTGCCGATGTCTTCCTGCGCGCACAACAGCACTGCGAGCAGGCTCGTCACTGGCACGCAT
CTTCTGCCCAGGGTCTGGAACAAGCGCTTGATGACAGTGTTGCGGCCTCGGGAAGAGCGCCGCAGTCATTGATACAGTCG
GTATTCTGCGACGGTGTTTCCGCGCGTGCAGAGCAGGGAGGCGCGTCGGGCAGTCTGCACTCGCCTCTCGAATTCGTCCT
GGACCGTTCCAGCACAAAGGCCTCGTTGTCACTCGGCTATGCTGCTGATCTGTTCGCTCAGGAAACAGCCACTTCAATGG
CCGGGCATTACGTCCAGTTGCTGGAAAAGGCCAGCGAATCACTGGACGAAACGCTGGCGCAAAGTCTATCGGCCCAGCAC
CAGGCTGCCATTCAGACACAGTGTGAAGGGCTTGACTCGAGCTATCCTGAAACGTCCCTGCACGCCATCGTCGAGGCCTT
TGCGGCCATACAGCCCGAGGCCATCGCTGTGCGGTGCGGCGATGCAGTGCTGACGTACGCTCAGCTCAATGAATCCGCCG
ACAAAGTTGCTGACACATTGCTTCGCAAGGGCGTGCAGCCGGGTGACGTCGTGGGCATCTGCATGATGCGCTCCGAATTG
CTGGTTGCGGCGCTGTTGGGCGTGCTCAAGGCCGGTGCATGCTACCTCTCGATCGACTGTGCATTGCCTGCAGAGCGTCG
TAATTGGCTTCTGGAGGAGGCGGACGTCAAGTGGGCACTGATCGATGAGAGTGCTCCGGCTTTACGTGATGCAACCTCAA
CACTGTTGATAGGGCAATTGGTGAATGAGCAGGACGACCCACGCGTGTCGCCGCTGGCCAAACCTGTCATCAGCGCGGAT
GCTCGCTGCTATTACATGTTTACATCGGGTTCCACGGGCACTCCGAAGGCCACGGCCAGTACCCACCGCGCGGTGGTGAG
TCTGGTCAAGGGTACGGACTATATCGATATCAAGGGTGACGACCGCTTCCTGTTTTTCGCGCCCCTCGCGTTCGATGCGT
CGACCTTTGAAATCTGGGGCGCCTTGCTGAACGGCGCGCAGTTGGTGGTTCAGCCTGGCGAAGCCGGCGGACTGGATGAC
CTGGCACACACACTGGAAAATCAGCAGGTCAGTGTGCTCTGGCTGACGTCCGCATTGTTCCAGGAGATGGTCGATCAATA
TCCTCAGGCGATGGCTGGCGTGAGGCATGTACTGACCGGCGGTGACGTTGTTTCGCCGCAAAGCATGCGCAGTTTGCTGG
CACGCTCCACCGGGACGCTCACCATCTGTTACGGCCCGACTGAAGGCACGGTCTTTACCACGGCCTACAGCATGGACAAG
GTCGAACAAGTGACTGACAAACCCTTGATCGGATGGCCGATTGCACAGGCCGATGCCTACATCGTGGATGTTTTCGGGCA
GCTTGCCGAGCCCGGTGTTCCAGGGGAGTTATTCATCGGCGGCACAGGGATCACCGGTGCCTACCTCAAGCGTCCGGAAC
TGAGCCAGGAGCGGTTTGTGACGCTGGAGCGGTTCCCCGGCAAAACACTCTTCCGCACCGGTGATCTGGCGCGCTGGACC
CCGGGCCGCGGTATCGAGTTCCTTGGACGCAGTGACAGTCAGATAAAGATCCGTGGGTTGCGTATAGAACCGGGTGAGGT
CGAGCAGGCGATACGTCAATTGCCGGGTGTCACAGCGTGCTCACTGATTCTGCGCACATTGAACCTGGACAAACAGCTGG
TCGCCTTCGTCAGTCTGGACGGCAGCGTTGCACTGGATGAGCAACAGATTCGTGTGGCGTTGAGAGAATGCCTGCCCGAC
TACATGGTGCCTGCCGAAGTGCATGTGATCGAGCAACTGCCGGTCAATGCGAGCGGCAAGGTCGACAAGCGTGCCTTGCT
TGAACTGGCGACTCAAAACGGCCGTGCAAGGGTTACCAGCGAGCGACCGTCGACGGCTCTGGAAAAATCCATTGCCGAGG
TCTGGGCGCACATCCTCAACGTGCCGGACGTGGGTAGAAATGAAGACTTCTTCTCCATCGGCGGACACTCGTTGGCCGGT
ATGCGGATCATGTCGAGGCTGAGCAAGCAATTTGGCACTCGTCTGTCGCTGAATCTGCTCTTCGAGTATCCCAGCGTCGA
GACGCTTGCAGGTGCTATCGAACGCTCGGCCGAGCCGTTGACGGCCTGA

Upstream 100 bases:

>100_bases
GTGGTCTTTTTAAAGAAGTCAATCACCGCTAACAAAAACGGATACACCGGTTTTTTTACGAGGTTGATGTCACCTGATCA
ATATGTTATCCGAGGCCGTC

Downstream 100 bases:

>100_bases
CCGTTTTTCAGGCGCGTGGTGGGTAGCAACAGCACCCCCACGCGCTTTCTCACCTCTCAGCCTCCCAATTTACCTTCCTC
GCAGCGACATCGGTCGCTGT

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Gramicidin S synthase II; ATP-dependent proline adenylase; ProA; Proline activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1322; Mature: 1322

Protein sequence:

>1322_residues
MNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQAWFLETLVPESIAYNFQAMLNIRGNLDINVLERALNRVVER
HQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVRQTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHVLLH
IEHHLIHDGWSFRLFLKELNHFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFP
AEKDAQAALDFVGSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQLIGTAVANRDLPGIENTIGM
LVNMLPLRIDIDANTSWAPLLAAVKEEIRTACLQSHVPFSTMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLDFADIDVE
VVEGLANGSAKFDLNVICVFDDEVNPAAGGRFMLEYSTAVAKEADVRALMADFLHLAGAWLEQPAESLANVRKSAVLAAP
SGSSSVNPGMEFWKQSLDLEASGLLPDHALNRAVSGPLARHEIPLPDESLARLFQACEQRNIEPEAALFSLYAVTMARYG
GHQTVVAGLGTAADGQRLAIPLPLKLTLAAHDTFADVFLRAQQHCEQARHWHASSAQGLEQALDDSVAASGRAPQSLIQS
VFCDGVSARAEQGGASGSLHSPLEFVLDRSSTKASLSLGYAADLFAQETATSMAGHYVQLLEKASESLDETLAQSLSAQH
QAAIQTQCEGLDSSYPETSLHAIVEAFAAIQPEAIAVRCGDAVLTYAQLNESADKVADTLLRKGVQPGDVVGICMMRSEL
LVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWALIDESAPALRDATSTLLIGQLVNEQDDPRVSPLAKPVISAD
ARCYYMFTSGSTGTPKATASTHRAVVSLVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDD
LAHTLENQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTLTICYGPTEGTVFTTAYSMDK
VEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIGGTGITGAYLKRPELSQERFVTLERFPGKTLFRTGDLARWT
PGRGIEFLGRSDSQIKIRGLRIEPGEVEQAIRQLPGVTACSLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPD
YMVPAEVHVIEQLPVNASGKVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILNVPDVGRNEDFFSIGGHSLAG
MRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPLTA

Sequences:

>Translated_1322_residues
MNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQAWFLETLVPESIAYNFQAMLNIRGNLDINVLERALNRVVER
HQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVRQTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHVLLH
IEHHLIHDGWSFRLFLKELNHFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFP
AEKDAQAALDFVGSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQLIGTAVANRDLPGIENTIGM
LVNMLPLRIDIDANTSWAPLLAAVKEEIRTACLQSHVPFSTMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLDFADIDVE
VVEGLANGSAKFDLNVICVFDDEVNPAAGGRFMLEYSTAVAKEADVRALMADFLHLAGAWLEQPAESLANVRKSAVLAAP
SGSSSVNPGMEFWKQSLDLEASGLLPDHALNRAVSGPLARHEIPLPDESLARLFQACEQRNIEPEAALFSLYAVTMARYG
GHQTVVAGLGTAADGQRLAIPLPLKLTLAAHDTFADVFLRAQQHCEQARHWHASSAQGLEQALDDSVAASGRAPQSLIQS
VFCDGVSARAEQGGASGSLHSPLEFVLDRSSTKASLSLGYAADLFAQETATSMAGHYVQLLEKASESLDETLAQSLSAQH
QAAIQTQCEGLDSSYPETSLHAIVEAFAAIQPEAIAVRCGDAVLTYAQLNESADKVADTLLRKGVQPGDVVGICMMRSEL
LVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWALIDESAPALRDATSTLLIGQLVNEQDDPRVSPLAKPVISAD
ARCYYMFTSGSTGTPKATASTHRAVVSLVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDD
LAHTLENQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTLTICYGPTEGTVFTTAYSMDK
VEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIGGTGITGAYLKRPELSQERFVTLERFPGKTLFRTGDLARWT
PGRGIEFLGRSDSQIKIRGLRIEPGEVEQAIRQLPGVTACSLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPD
YMVPAEVHVIEQLPVNASGKVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILNVPDVGRNEDFFSIGGHSLAG
MRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPLTA
>Mature_1322_residues
MNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQAWFLETLVPESIAYNFQAMLNIRGNLDINVLERALNRVVER
HQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVRQTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHVLLH
IEHHLIHDGWSFRLFLKELNHFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFP
AEKDAQAALDFVGSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQLIGTAVANRDLPGIENTIGM
LVNMLPLRIDIDANTSWAPLLAAVKEEIRTACLQSHVPFSTMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLDFADIDVE
VVEGLANGSAKFDLNVICVFDDEVNPAAGGRFMLEYSTAVAKEADVRALMADFLHLAGAWLEQPAESLANVRKSAVLAAP
SGSSSVNPGMEFWKQSLDLEASGLLPDHALNRAVSGPLARHEIPLPDESLARLFQACEQRNIEPEAALFSLYAVTMARYG
GHQTVVAGLGTAADGQRLAIPLPLKLTLAAHDTFADVFLRAQQHCEQARHWHASSAQGLEQALDDSVAASGRAPQSLIQS
VFCDGVSARAEQGGASGSLHSPLEFVLDRSSTKASLSLGYAADLFAQETATSMAGHYVQLLEKASESLDETLAQSLSAQH
QAAIQTQCEGLDSSYPETSLHAIVEAFAAIQPEAIAVRCGDAVLTYAQLNESADKVADTLLRKGVQPGDVVGICMMRSEL
LVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWALIDESAPALRDATSTLLIGQLVNEQDDPRVSPLAKPVISAD
ARCYYMFTSGSTGTPKATASTHRAVVSLVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDD
LAHTLENQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTLTICYGPTEGTVFTTAYSMDK
VEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIGGTGITGAYLKRPELSQERFVTLERFPGKTLFRTGDLARWT
PGRGIEFLGRSDSQIKIRGLRIEPGEVEQAIRQLPGVTACSLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPD
YMVPAEVHVIEQLPVNASGKVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILNVPDVGRNEDFFSIGGHSLAG
MRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPLTA

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=437, Percent_Identity=29.5194508009153, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI156151445, Length=538, Percent_Identity=22.4907063197026, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI42544132, Length=357, Percent_Identity=23.249299719888, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI115511026, Length=375, Percent_Identity=24.5333333333333, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI187761345, Length=381, Percent_Identity=25.4593175853018, Blast_Score=74, Evalue=9e-13,
Organism=Homo sapiens, GI187761343, Length=381, Percent_Identity=25.4593175853018, Blast_Score=74, Evalue=9e-13,
Organism=Homo sapiens, GI38505220, Length=496, Percent_Identity=21.9758064516129, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1786801, Length=604, Percent_Identity=31.7880794701987, Blast_Score=241, Evalue=3e-64,
Organism=Escherichia coli, GI1786810, Length=512, Percent_Identity=25.390625, Blast_Score=97, Evalue=8e-21,
Organism=Escherichia coli, GI145693145, Length=549, Percent_Identity=24.0437158469945, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788107, Length=521, Percent_Identity=21.4971209213052, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=571, Percent_Identity=25.7443082311734, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17550940, Length=440, Percent_Identity=25.2272727272727, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71985884, Length=358, Percent_Identity=25.6983240223464, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=500, Percent_Identity=21.4, Blast_Score=86, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319591, Length=760, Percent_Identity=25.3947368421053, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6319699, Length=252, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648676, Length=648, Percent_Identity=27.7777777777778, Blast_Score=160, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24581924, Length=517, Percent_Identity=23.0174081237911, Blast_Score=91, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 144106; Mature: 144106

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQAWFLETLVPESIAYNFQAMLN
CCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEE
IRGNLDINVLERALNRVVERHQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHH
QTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHVLLHIEHHLIHDGWSFRLFLKELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHCCCCHHHHHHHHHH
HFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFP
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCC
AEKDAQAALDFVGSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQ
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LIGTAVANRDLPGIENTIGMLVNMLPLRIDIDANTSWAPLLAAVKEEIRTACLQSHVPFS
HHHHHHHCCCCCCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHH
TMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLDFADIDVEVVEGLANGSAKFDLNVICVF
HHHHCCCHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
DDEVNPAAGGRFMLEYSTAVAKEADVRALMADFLHLAGAWLEQPAESLANVRKSAVLAAP
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
SGSSSVNPGMEFWKQSLDLEASGLLPDHALNRAVSGPLARHEIPLPDESLARLFQACEQR
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
NIEPEAALFSLYAVTMARYGGHQTVVAGLGTAADGQRLAIPLPLKLTLAAHDTFADVFLR
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCEEEEEECHHHHHHHHHH
AQQHCEQARHWHASSAQGLEQALDDSVAASGRAPQSLIQSVFCDGVSARAEQGGASGSLH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCC
SPLEFVLDRSSTKASLSLGYAADLFAQETATSMAGHYVQLLEKASESLDETLAQSLSAQH
CCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAIQTQCEGLDSSYPETSLHAIVEAFAAIQPEAIAVRCGDAVLTYAQLNESADKVADTL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHH
LRKGVQPGDVVGICMMRSELLVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWAL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCHHHCCCEEEE
IDESAPALRDATSTLLIGQLVNEQDDPRVSPLAKPVISADARCYYMFTSGSTGTPKATAS
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
THRAVVSLVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDD
HHHHHHHHHCCCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHH
LAHTLENQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTL
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCE
TICYGPTEGTVFTTAYSMDKVEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIG
EEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEC
GTGITGAYLKRPELSQERFVTLERFPGKTLFRTGDLARWTPGRGIEFLGRSDSQIKIRGL
CCCCCCHHHCCCCCCHHHEEEHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
RIEPGEVEQAIRQLPGVTACSLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPD
ECCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEEECCCCEEECHHHHHHHHHHHCCC
YMVPAEVHVIEQLPVNASGKVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILN
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHC
VPDVGRNEDFFSIGGHSLAGMRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHCCCCC
TA
CC
>Mature Secondary Structure
MNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQAWFLETLVPESIAYNFQAMLN
CCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEE
IRGNLDINVLERALNRVVERHQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHH
QTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHVLLHIEHHLIHDGWSFRLFLKELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHCCCCHHHHHHHHHH
HFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFP
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCC
AEKDAQAALDFVGSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQ
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LIGTAVANRDLPGIENTIGMLVNMLPLRIDIDANTSWAPLLAAVKEEIRTACLQSHVPFS
HHHHHHHCCCCCCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHH
TMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLDFADIDVEVVEGLANGSAKFDLNVICVF
HHHHCCCHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
DDEVNPAAGGRFMLEYSTAVAKEADVRALMADFLHLAGAWLEQPAESLANVRKSAVLAAP
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
SGSSSVNPGMEFWKQSLDLEASGLLPDHALNRAVSGPLARHEIPLPDESLARLFQACEQR
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
NIEPEAALFSLYAVTMARYGGHQTVVAGLGTAADGQRLAIPLPLKLTLAAHDTFADVFLR
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCEEEEEECHHHHHHHHHH
AQQHCEQARHWHASSAQGLEQALDDSVAASGRAPQSLIQSVFCDGVSARAEQGGASGSLH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCC
SPLEFVLDRSSTKASLSLGYAADLFAQETATSMAGHYVQLLEKASESLDETLAQSLSAQH
CCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAIQTQCEGLDSSYPETSLHAIVEAFAAIQPEAIAVRCGDAVLTYAQLNESADKVADTL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHH
LRKGVQPGDVVGICMMRSELLVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWAL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCHHHCCCEEEE
IDESAPALRDATSTLLIGQLVNEQDDPRVSPLAKPVISADARCYYMFTSGSTGTPKATAS
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
THRAVVSLVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDD
HHHHHHHHHCCCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHH
LAHTLENQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTL
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCE
TICYGPTEGTVFTTAYSMDKVEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIG
EEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEC
GTGITGAYLKRPELSQERFVTLERFPGKTLFRTGDLARWTPGRGIEFLGRSDSQIKIRGL
CCCCCCHHHCCCCCCHHHEEEHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
RIEPGEVEQAIRQLPGVTACSLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPD
ECCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEEECCCCEEECHHHHHHHHHHHCCC
YMVPAEVHVIEQLPVNASGKVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILN
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHC
VPDVGRNEDFFSIGGHSLAGMRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHCCCCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1560782; 2477357 [H]