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The map label for this gene is fabD [H]

Identifier: 66044891

GI number: 66044891

Start: 1851557

End: 1852495

Strand: Direct

Name: fabD [H]

Synonym: Psyr_1646

Alternate gene names: 66044891

Gene position: 1851557-1852495 (Clockwise)

Preceding gene: 66044890

Following gene: 66044892

Centisome position: 30.38

GC content: 64.22

Gene sequence:

>939_bases
ATGTCTGCATCCCTCGCATTCGTCTTTCCGGGTCAAGGATCGCAATCGCTCGGTATGCTCGCCGAGCAAGGCGCGCACCA
CCCGCTGATCCTCGACACTTTCGAGCAGGCTTCCGAAGCCCTCGGCTATGACCTGTGGGCATTGACTCAGAACGGTCCTG
CCGAGCTGCTCAACCAGACCGACAAGACCCAGCCGGCCATTCTGACCGCATCCGTTGCCTTGTGGCACGTGTGGCTGGCC
GAGGGCGGTGCGGTTCCTGCATTCGTCGCCGGTCACAGTCTGGGTGAATACAGCGCACTGGTAGCCGCGCAAAGCCTGAG
CCTGGCCGACGCCGTAAAGCTTGTCGAGCGTCGCGGCCAGTTGATGCAGGAAGCGGTGCCGGCGGGTCAGGGCGGCATGG
CCGCCATTCTGGGTCTGGATGATGCCGACGTTATTGCAGCCTGCGCCGAAGCGGCACAGGGTGAAGTCGTCAGCGCGGTG
AATTTCAACTCGCCGGGTCAGGTGGTGATCGCCGGTTCCGCCGAGGCCGTCAAGCGTGCCATGGAGCTGTGCAAGGCCCG
TGGCGCCAAGCGCGCCTTGCCATTGCCGGTCAGCGTGCCATCGCACTGCGAACTGATGCGCCCGGCCGCCGAGCGTTTCG
CCGAGGCCGTTGAAGCCATCGAATGGCAAGCGCCGGAAATTGCGCTGGTACAGAACGTCAGCGCCAGTGCCGTCAGTGAT
CTGGCGACGCTCAAGCGTGATTTGCTGGAGCAGTTGTACAAGCCGGTGCGTTGGGTCGAGTCCATTCAATGCCTGGCGAG
CCGCGGTGCGACCCAGCTCGTGGAATGCGGTCCGGGCAAAGTGCTGGCCGGTCTGAACAAACGTTGCGCCGACGGCGTGA
TGACCTACAACCTTGATACCCCGGACGCCTTTGCCGCCGCGCGCGCGGCACTGGCCTGA

Upstream 100 bases:

>100_bases
ACTGGTCAGTCATCCAACCGATCAGTCATGTACATTAGAATTCCCGCGTTCGGCCTGTCCGGACGCCCATTTTGGCGACA
ATAATTCAGAGGCTTGTCAA

Downstream 100 bases:

>100_bases
TTAGGAGAAGCCTGCATGAGCCTTCAAGGTAAAGTGGCACTGGTAACCGGTGCAAGTCGCGGCATTGGCCAAGCCATTGC
TCTGGAATTGGGACGCAACG

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSASLAFVFPGQGSQSLGMLAEQGAHHPLILDTFEQASEALGYDLWALTQNGPAELLNQTDKTQPAILTASVALWHVWLA
EGGAVPAFVAGHSLGEYSALVAAQSLSLADAVKLVERRGQLMQEAVPAGQGGMAAILGLDDADVIAACAEAAQGEVVSAV
NFNSPGQVVIAGSAEAVKRAMELCKARGAKRALPLPVSVPSHCELMRPAAERFAEAVEAIEWQAPEIALVQNVSASAVSD
LATLKRDLLEQLYKPVRWVESIQCLASRGATQLVECGPGKVLAGLNKRCADGVMTYNLDTPDAFAAARAALA

Sequences:

>Translated_312_residues
MSASLAFVFPGQGSQSLGMLAEQGAHHPLILDTFEQASEALGYDLWALTQNGPAELLNQTDKTQPAILTASVALWHVWLA
EGGAVPAFVAGHSLGEYSALVAAQSLSLADAVKLVERRGQLMQEAVPAGQGGMAAILGLDDADVIAACAEAAQGEVVSAV
NFNSPGQVVIAGSAEAVKRAMELCKARGAKRALPLPVSVPSHCELMRPAAERFAEAVEAIEWQAPEIALVQNVSASAVSD
LATLKRDLLEQLYKPVRWVESIQCLASRGATQLVECGPGKVLAGLNKRCADGVMTYNLDTPDAFAAARAALA
>Mature_311_residues
SASLAFVFPGQGSQSLGMLAEQGAHHPLILDTFEQASEALGYDLWALTQNGPAELLNQTDKTQPAILTASVALWHVWLAE
GGAVPAFVAGHSLGEYSALVAAQSLSLADAVKLVERRGQLMQEAVPAGQGGMAAILGLDDADVIAACAEAAQGEVVSAVN
FNSPGQVVIAGSAEAVKRAMELCKARGAKRALPLPVSVPSHCELMRPAAERFAEAVEAIEWQAPEIALVQNVSASAVSDL
ATLKRDLLEQLYKPVRWVESIQCLASRGATQLVECGPGKVLAGLNKRCADGVMTYNLDTPDAFAAARAALA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=305, Percent_Identity=32.1311475409836, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1787334, Length=303, Percent_Identity=59.7359735973597, Blast_Score=344, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.3993174061433, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=296, Percent_Identity=28.0405405405405, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=33.003300330033, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32520; Mature: 32389

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLAFVFPGQGSQSLGMLAEQGAHHPLILDTFEQASEALGYDLWALTQNGPAELLNQT
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCEEEEECCCCHHHHHCCC
DKTQPAILTASVALWHVWLAEGGAVPAFVAGHSLGEYSALVAAQSLSLADAVKLVERRGQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQEAVPAGQGGMAAILGLDDADVIAACAEAAQGEVVSAVNFNSPGQVVIAGSAEAVKRA
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHH
MELCKARGAKRALPLPVSVPSHCELMRPAAERFAEAVEAIEWQAPEIALVQNVSASAVSD
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LATLKRDLLEQLYKPVRWVESIQCLASRGATQLVECGPGKVLAGLNKRCADGVMTYNLDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCHHHHCCEEEEECCC
PDAFAAARAALA
CHHHHHHHHHCC
>Mature Secondary Structure 
SASLAFVFPGQGSQSLGMLAEQGAHHPLILDTFEQASEALGYDLWALTQNGPAELLNQT
CCCEEEEECCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCEEEEECCCCHHHHHCCC
DKTQPAILTASVALWHVWLAEGGAVPAFVAGHSLGEYSALVAAQSLSLADAVKLVERRGQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQEAVPAGQGGMAAILGLDDADVIAACAEAAQGEVVSAVNFNSPGQVVIAGSAEAVKRA
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHH
MELCKARGAKRALPLPVSVPSHCELMRPAAERFAEAVEAIEWQAPEIALVQNVSASAVSD
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LATLKRDLLEQLYKPVRWVESIQCLASRGATQLVECGPGKVLAGLNKRCADGVMTYNLDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCHHHHCCEEEEECCC
PDAFAAARAALA
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]