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The map label for this gene is carR [H]

Identifier: 66044867

GI number: 66044867

Start: 1823413

End: 1824156

Strand: Reverse

Name: carR [H]

Synonym: Psyr_1622

Alternate gene names: 66044867

Gene position: 1824156-1823413 (Counterclockwise)

Preceding gene: 66044869

Following gene: 66044865

Centisome position: 29.94

GC content: 53.23

Gene sequence:

>744_bases
ATGGAGGTTCGTACCGTGCACACCCAACTTGACTGCCCGCCCCTCAAGATCAACGCAGCCCCTGCTCCGCTGCGTCAATT
GATTGAAGACTTCGAAAACGATCTGCATCGTATTGGCGATTTCACCTATGCCTACTTTTCCAGCCCAAAGACACGCACTG
TCAAACCGGTCATCCTGTCCAACTATCCTGATTCCTGGCTGAAGTCGTATATTGCCTCCAACTATCACCTTATCGATCCC
ATCATCAAACATGCCTGGCATAGCATTACGCCATTTTTCTGGAGAGAGGCCCGGCATGCCATTCAGGGCGTCGAGACCGA
TGACTTCCTGAAGCGCTCGGCCAAATACCAGCTGTCCTCCGGGGCCACTTTCACCCTGCACGATGCAAGCGGGCTTTTTG
CCGCTCTGAGTCTTTGCAATGCCAGGCAACAGACTGACTTCGATCAGCGAATCCGCGACAAGGCCGCTGATATCCAGATG
AGCCTCATCCGCTTTCATGACCGTTTGACCAAGACACAGGCGCCCCACGAACTCTTCCCGCAGCCCACCCGATGCAAATT
ATCCAGCCGCGAAATAGGCGTGCTGAAATGGGTAGCCATGGGCAAGGCCTACAGCGAAATCGCCGAGATATTTTCCATTT
CGGAACGCACCGTGAAATTTCACATGTCCAACGTTTCCAGCAAACTCGAAGTGCGCACTGCCAAACAGGCCGTGTACAAA
GCCATTAATATGGGCATGGTCTGA

Upstream 100 bases:

>100_bases
CAAAAGACACACGCAGTCCATGTTTTCATGTACTGCGGAAAATACAAATGAGGATAATGAAGACGGCCAGGCCGCAAACA
AACAATAGACAAGGTATTAC

Downstream 100 bases:

>100_bases
CTCAGGCTGCGCTGTCCATGCGTGCTCGCTGCAAGGATGCTGATGCATCGAGCGGTATTGGCCAGCGCAACAGGTCATCC
GTGACGGGCTGCCTGAGAGC

Product: LuxR transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEVRTVHTQLDCPPLKINAAPAPLRQLIEDFENDLHRIGDFTYAYFSSPKTRTVKPVILSNYPDSWLKSYIASNYHLIDP
IIKHAWHSITPFFWREARHAIQGVETDDFLKRSAKYQLSSGATFTLHDASGLFAALSLCNARQQTDFDQRIRDKAADIQM
SLIRFHDRLTKTQAPHELFPQPTRCKLSSREIGVLKWVAMGKAYSEIAEIFSISERTVKFHMSNVSSKLEVRTAKQAVYK
AINMGMV

Sequences:

>Translated_247_residues
MEVRTVHTQLDCPPLKINAAPAPLRQLIEDFENDLHRIGDFTYAYFSSPKTRTVKPVILSNYPDSWLKSYIASNYHLIDP
IIKHAWHSITPFFWREARHAIQGVETDDFLKRSAKYQLSSGATFTLHDASGLFAALSLCNARQQTDFDQRIRDKAADIQM
SLIRFHDRLTKTQAPHELFPQPTRCKLSSREIGVLKWVAMGKAYSEIAEIFSISERTVKFHMSNVSSKLEVRTAKQAVYK
AINMGMV
>Mature_247_residues
MEVRTVHTQLDCPPLKINAAPAPLRQLIEDFENDLHRIGDFTYAYFSSPKTRTVKPVILSNYPDSWLKSYIASNYHLIDP
IIKHAWHSITPFFWREARHAIQGVETDDFLKRSAKYQLSSGATFTLHDASGLFAALSLCNARQQTDFDQRIRDKAADIQM
SLIRFHDRLTKTQAPHELFPQPTRCKLSSREIGVLKWVAMGKAYSEIAEIFSISERTVKFHMSNVSSKLEVRTAKQAVYK
AINMGMV

Specific function: Functions as an OHLL responsive transcriptional regulator which acts in the control of the biosynthesis of carbapenem antibiotics [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788224, Length=238, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 28274; Mature: 28274

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRTVHTQLDCPPLKINAAPAPLRQLIEDFENDLHRIGDFTYAYFSSPKTRTVKPVILS
CCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCEEEC
NYPDSWLKSYIASNYHLIDPIIKHAWHSITPFFWREARHAIQGVETDDFLKRSAKYQLSS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECC
GATFTLHDASGLFAALSLCNARQQTDFDQRIRDKAADIQMSLIRFHDRLTKTQAPHELFP
CCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
QPTRCKLSSREIGVLKWVAMGKAYSEIAEIFSISERTVKFHMSNVSSKLEVRTAKQAVYK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AINMGMV
HHHCCCC
>Mature Secondary Structure
MEVRTVHTQLDCPPLKINAAPAPLRQLIEDFENDLHRIGDFTYAYFSSPKTRTVKPVILS
CCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCEEEC
NYPDSWLKSYIASNYHLIDPIIKHAWHSITPFFWREARHAIQGVETDDFLKRSAKYQLSS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECC
GATFTLHDASGLFAALSLCNARQQTDFDQRIRDKAADIQMSLIRFHDRLTKTQAPHELFP
CCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
QPTRCKLSSREIGVLKWVAMGKAYSEIAEIFSISERTVKFHMSNVSSKLEVRTAKQAVYK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AINMGMV
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7711893 [H]