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The map label for this gene is hlyB [H]

Identifier: 66044738

GI number: 66044738

Start: 1678195

End: 1679814

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_1491

Alternate gene names: 66044738

Gene position: 1679814-1678195 (Counterclockwise)

Preceding gene: 66044746

Following gene: 66044736

Centisome position: 27.57

GC content: 54.51

Gene sequence:

>1620_bases
ATGCGGCTCAGAAATATAAACCTCGCTCCACGCGCCACCTTGTTTTTTTCGGCCATCATTTTGCTGGTCGTGGTCTTGGG
CGTCATCGCCATACTGCAGATGGGCAAGCTTCGCGATACGGAAAAGGATGTCGAACTGAATTGGCTACCCAGTATTCGGC
AAACCGCGATGATGAACTCCACCGTCCTTCGCGTCCGGTTGGAGACCCAGCGGGCCGTTGCCGATCCTCAAACCGTTCAG
CAGACCATCGTCAAATTTCCTGCCTACCGGAAAGCCATGAAGGATGCGGTCTATAACTATGAGACCCTCATTGCGAGTGA
CCAGGAGCGACAGTTGTTCTTGGCCGTGAAAAAGTCCTACGACGATTACGCAAGCCAACTGGATCTGCTGGAACCTTTGT
TGAAGGCAGGCGACACCGCTTCGATTGTCAAACTCGTCGCTACCGGTATACGTCCCCTCACGAACCAAATGGAAACTCAG
GTCGAGGAATTAACACAATTCAATAACAAAGGCGCTGCGCTTGCCGGTGTTCAAGCGACGCAAGTTTATGATTCAGGTCT
TTACATCGTCATCGGCCTGATTATCTTCGTCGCGCTCCTGACTCTTTGTTTGGCAACTCTTCTAACCAAAACGATTACGT
CGCCCATCGGGAGCGCCCTTAGCGTCGCCGAACGCATTGCCTCAAGCGATCTGACGAAGGAGGTTGAGGTAAGCGGTACC
GACGAGGCAGGCAGGCTTTTGAGCGCGTTGGCCACGATGCAGCAGAACCTTCGAAGCACGATCATGCAGATCGCTGACTC
CTCATCCCAACTGGCTGCCGCCTCGGAAGAAATGACCGCGGTGACTGAGCAATCCAGCCTTGGCCTGGTGTCGCAGAATG
ATGAAGTAAATCAGGCTGCAACTGCTGTCACCGAGATGAGCGCTGCAGTGGACGAGGTAGCACGCAATGCCGAATCAGCT
TCCGAAGAGTCCAGGAAAGGTCAGGGCTATACGGAGGTTGGTTTGGAGCGTGTATCGCAGACGCTTAAGTCCATCGAAAA
GCTGTCGAGCAACGTGCGCGACACCAGCGAGCAGATCACTGGCTTGTCCAATCGTGCACAGAACATTTCCAAAGTGGTTG
AGGTGATCAGAGCCATTGCTGAGCAGACCAATCTGCTTGCGCTCAATGCCGCGATCGAGGCCGCTAGGGCGGGTGAACAA
GGCCGAGGCTTCGCAGTCGTTGCTGACGAAGTTCGAGCCCTCGCTCACCGCACGCAAGTGTCTACGCAAGAAATTGAGCA
GATGATTCAGGCCATTCAGAACGATTCTGACCAGGCCGTGAAGGCGATGGCCACCAGCAGAGAACTGGCTGCAGAATCCC
TAAGCGTCGCAGGCGATGCCAGCAGTTCGCTTGACCAGATCGCGACAGCTATTACGGGCATCAACGAGCGTAACATTCTC
ATCGCCACCGCTTCGGAAGAACAGGCGCACGTCGCCCGGGAAGTCGATCGCAATCTGGTTAGCATTCGCGAGCTGGCCTC
CCAAAGTTCTGCAGGTGCAAGCCAGACTGCAAGCGCTTGCAACGAGATGTCGAAGCTTGCGGTTAGTCTGAATCAGCTGG
TCAATCGTTTCAAGGTTTAA

Upstream 100 bases:

>100_bases
GACGTGGTGTCAACGAGCTGACGAACAGCCATAATCCTTCACGATTTCTAGCCGATAGCTTCAAGACCAGGCCTCTGGCC
ATCTTGCAGTGGGAAGTCCT

Downstream 100 bases:

>100_bases
GGTATTCACGTACGTCAGCGGACTCGTCCGATGTCCTTGGATATCGGACCTAGACTGTCGACTGTGCCTTGGCGATATAC
CGTCCTCCCTGAGCGTGAGC

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MRLRNINLAPRATLFFSAIILLVVVLGVIAILQMGKLRDTEKDVELNWLPSIRQTAMMNSTVLRVRLETQRAVADPQTVQ
QTIVKFPAYRKAMKDAVYNYETLIASDQERQLFLAVKKSYDDYASQLDLLEPLLKAGDTASIVKLVATGIRPLTNQMETQ
VEELTQFNNKGAALAGVQATQVYDSGLYIVIGLIIFVALLTLCLATLLTKTITSPIGSALSVAERIASSDLTKEVEVSGT
DEAGRLLSALATMQQNLRSTIMQIADSSSQLAAASEEMTAVTEQSSLGLVSQNDEVNQAATAVTEMSAAVDEVARNAESA
SEESRKGQGYTEVGLERVSQTLKSIEKLSSNVRDTSEQITGLSNRAQNISKVVEVIRAIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAHRTQVSTQEIEQMIQAIQNDSDQAVKAMATSRELAAESLSVAGDASSSLDQIATAITGINERNIL
IATASEEQAHVAREVDRNLVSIRELASQSSAGASQTASACNEMSKLAVSLNQLVNRFKV

Sequences:

>Translated_539_residues
MRLRNINLAPRATLFFSAIILLVVVLGVIAILQMGKLRDTEKDVELNWLPSIRQTAMMNSTVLRVRLETQRAVADPQTVQ
QTIVKFPAYRKAMKDAVYNYETLIASDQERQLFLAVKKSYDDYASQLDLLEPLLKAGDTASIVKLVATGIRPLTNQMETQ
VEELTQFNNKGAALAGVQATQVYDSGLYIVIGLIIFVALLTLCLATLLTKTITSPIGSALSVAERIASSDLTKEVEVSGT
DEAGRLLSALATMQQNLRSTIMQIADSSSQLAAASEEMTAVTEQSSLGLVSQNDEVNQAATAVTEMSAAVDEVARNAESA
SEESRKGQGYTEVGLERVSQTLKSIEKLSSNVRDTSEQITGLSNRAQNISKVVEVIRAIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAHRTQVSTQEIEQMIQAIQNDSDQAVKAMATSRELAAESLSVAGDASSSLDQIATAITGINERNIL
IATASEEQAHVAREVDRNLVSIRELASQSSAGASQTASACNEMSKLAVSLNQLVNRFKV
>Mature_539_residues
MRLRNINLAPRATLFFSAIILLVVVLGVIAILQMGKLRDTEKDVELNWLPSIRQTAMMNSTVLRVRLETQRAVADPQTVQ
QTIVKFPAYRKAMKDAVYNYETLIASDQERQLFLAVKKSYDDYASQLDLLEPLLKAGDTASIVKLVATGIRPLTNQMETQ
VEELTQFNNKGAALAGVQATQVYDSGLYIVIGLIIFVALLTLCLATLLTKTITSPIGSALSVAERIASSDLTKEVEVSGT
DEAGRLLSALATMQQNLRSTIMQIADSSSQLAAASEEMTAVTEQSSLGLVSQNDEVNQAATAVTEMSAAVDEVARNAESA
SEESRKGQGYTEVGLERVSQTLKSIEKLSSNVRDTSEQITGLSNRAQNISKVVEVIRAIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAHRTQVSTQEIEQMIQAIQNDSDQAVKAMATSRELAAESLSVAGDASSSLDQIATAITGINERNIL
IATASEEQAHVAREVDRNLVSIRELASQSSAGASQTASACNEMSKLAVSLNQLVNRFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=419, Percent_Identity=29.8329355608592, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI2367378, Length=404, Percent_Identity=29.2079207920792, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788194, Length=369, Percent_Identity=29.810298102981, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=29.5302013422819, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789453, Length=272, Percent_Identity=29.7794117647059, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57978; Mature: 57978

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRNINLAPRATLFFSAIILLVVVLGVIAILQMGKLRDTEKDVELNWLPSIRQTAMMNS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TVLRVRLETQRAVADPQTVQQTIVKFPAYRKAMKDAVYNYETLIASDQERQLFLAVKKSY
HHEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DDYASQLDLLEPLLKAGDTASIVKLVATGIRPLTNQMETQVEELTQFNNKGAALAGVQAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHH
QVYDSGLYIVIGLIIFVALLTLCLATLLTKTITSPIGSALSVAERIASSDLTKEVEVSGT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
DEAGRLLSALATMQQNLRSTIMQIADSSSQLAAASEEMTAVTEQSSLGLVSQNDEVNQAA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TAVTEMSAAVDEVARNAESASEESRKGQGYTEVGLERVSQTLKSIEKLSSNVRDTSEQIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSNRAQNISKVVEVIRAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAHRTQV
HHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCC
STQEIEQMIQAIQNDSDQAVKAMATSRELAAESLSVAGDASSSLDQIATAITGINERNIL
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEE
IATASEEQAHVAREVDRNLVSIRELASQSSAGASQTASACNEMSKLAVSLNQLVNRFKV
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLRNINLAPRATLFFSAIILLVVVLGVIAILQMGKLRDTEKDVELNWLPSIRQTAMMNS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TVLRVRLETQRAVADPQTVQQTIVKFPAYRKAMKDAVYNYETLIASDQERQLFLAVKKSY
HHEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DDYASQLDLLEPLLKAGDTASIVKLVATGIRPLTNQMETQVEELTQFNNKGAALAGVQAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHH
QVYDSGLYIVIGLIIFVALLTLCLATLLTKTITSPIGSALSVAERIASSDLTKEVEVSGT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
DEAGRLLSALATMQQNLRSTIMQIADSSSQLAAASEEMTAVTEQSSLGLVSQNDEVNQAA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TAVTEMSAAVDEVARNAESASEESRKGQGYTEVGLERVSQTLKSIEKLSSNVRDTSEQIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSNRAQNISKVVEVIRAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAHRTQV
HHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCC
STQEIEQMIQAIQNDSDQAVKAMATSRELAAESLSVAGDASSSLDQIATAITGINERNIL
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEE
IATASEEQAHVAREVDRNLVSIRELASQSSAGASQTASACNEMSKLAVSLNQLVNRFKV
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]