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The map label for this gene is truD [H]

Identifier: 66044618

GI number: 66044618

Start: 1553050

End: 1554108

Strand: Direct

Name: truD [H]

Synonym: Psyr_1370

Alternate gene names: 66044618

Gene position: 1553050-1554108 (Clockwise)

Preceding gene: 66044617

Following gene: 66044619

Centisome position: 25.49

GC content: 62.8

Gene sequence:

>1059_bases
ATGAACGAACTTGAACTGCTGGGCCCGCGAGCTTACGGCGAGGCGCTGGGGCGTGCAGTCCTCAAGGCGACTGCCGAAGA
CTTTCAGGTCGACGAAGTGCTGGACATTCCGCTTTCCGGGGATGGCGAGCACTTGTGGCTATGGGTCGAGAAGCGCGGTC
TGAACACGGAAGAGGCGGCACGTCGGCTGGCCAGGGCTGCGGGCGTTCAGCTGCGCACAGTCAGCTACGCCGGGCTCAAG
GATCGCCAGGCACTGACCCGCCAGTGGTTCAGCATTCAACTGCCGGGCAAGGCCGATCCTGACCTGTCCGCGGCGCAGGA
CGACACGCTGCAGATTCTCAAGAGCGGCCGCCACAAACGCAAGCTGCAGCGCGGCGCCCATGCGGCCAATGGCTTCACGC
TGCGTCTGACCCAGCTGGATGCAGACAAGGACGCCTTGAATCAGCGTCTTGAAACCATCGCCCGGCAGGGCATCCCCAAT
TATTTCGGCGCGCAGCGTTTCGGTTATCAGGGCGGAAATCTTGGCGAGGCACGCGATTACGCCGCCCGCAAGGCGCTGCC
TGAGCAACGCGCGGTGCGTTCGCGACTGTTGTCCACGGCGCGCAGTTACCTGTTCAATCGGGTGTTGGCCGCCCGGGTTG
CCGATGGCAGCTGGCAGAAGGCTCAGGTCGGTGATTTGCTCGCGTTCACCGACAGCCGCAGCTTTTTTCCGGCCGGGGTG
GATGAATGCAGCGATCCTCGTCTGGCGATCCTCGACCTGCACCCCACCGGACCACAGTGGGGTGAAGGCCCTTCGCCAGC
TGGCGGTGCGACGGCAGCGCTGGAAAATACCGTTGCCGATGACGAATCTGTGTTGCGTGACTGGCTGGTCAGAGCGGGCA
TGGAGCACGAACGTCGCATCCTGCGACTGCCCATTGGGCGGCTGACGTGGCATTATCCCGAGTCTGACATTCTGCAACTG
GAATTCGTCCTTCCGCCCGGATGCTTTGCTACCGTTTTGGTCCGCGAACTCATCGATCTGGTGCCGGTTGGGCAGACGGA
CAGCTCATGCGTATTCTGA

Upstream 100 bases:

>100_bases
CGGACCAGGTCAACGTCAAGGCCACAACGACCGAAAAGCTTGGCTTTACCGGGCGTGAAGAAGGCATCGCGGTGCATGCC
GTTGCGTTGTTGCTGCGCGC

Downstream 100 bases:

>100_bases
TATCAAATGATGACGGGGTGAATGCGCCCGGTCTTGTCGCGCTCCATGCGGCGTTGGCGGACTACGCCGACTGCGTGGTG
ATTGCGCCTGATCAGGACAA

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNELELLGPRAYGEALGRAVLKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAARRLARAAGVQLRTVSYAGLK
DRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSGRHKRKLQRGAHAANGFTLRLTQLDADKDALNQRLETIARQGIPN
YFGAQRFGYQGGNLGEARDYAARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWQKAQVGDLLAFTDSRSFFPAGV
DECSDPRLAILDLHPTGPQWGEGPSPAGGATAALENTVADDESVLRDWLVRAGMEHERRILRLPIGRLTWHYPESDILQL
EFVLPPGCFATVLVRELIDLVPVGQTDSSCVF

Sequences:

>Translated_352_residues
MNELELLGPRAYGEALGRAVLKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAARRLARAAGVQLRTVSYAGLK
DRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSGRHKRKLQRGAHAANGFTLRLTQLDADKDALNQRLETIARQGIPN
YFGAQRFGYQGGNLGEARDYAARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWQKAQVGDLLAFTDSRSFFPAGV
DECSDPRLAILDLHPTGPQWGEGPSPAGGATAALENTVADDESVLRDWLVRAGMEHERRILRLPIGRLTWHYPESDILQL
EFVLPPGCFATVLVRELIDLVPVGQTDSSCVF
>Mature_352_residues
MNELELLGPRAYGEALGRAVLKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAARRLARAAGVQLRTVSYAGLK
DRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSGRHKRKLQRGAHAANGFTLRLTQLDADKDALNQRLETIARQGIPN
YFGAQRFGYQGGNLGEARDYAARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWQKAQVGDLLAFTDSRSFFPAGV
DECSDPRLAILDLHPTGPQWGEGPSPAGGATAALENTVADDESVLRDWLVRAGMEHERRILRLPIGRLTWHYPESDILQL
EFVLPPGCFATVLVRELIDLVPVGQTDSSCVF

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=335, Percent_Identity=38.5074626865672, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 38875; Mature: 38875

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELELLGPRAYGEALGRAVLKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEECCCCCHHHHH
RRLARAAGVQLRTVSYAGLKDRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSGRHKR
HHHHHHHCCEEEEEEECCCHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHCCHHHH
KLQRGAHAANGFTLRLTQLDADKDALNQRLETIARQGIPNYFGAQRFGYQGGNLGEARDY
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHH
AARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWQKAQVGDLLAFTDSRSFFPAGV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCCC
DECSDPRLAILDLHPTGPQWGEGPSPAGGATAALENTVADDESVLRDWLVRAGMEHERRI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
LRLPIGRLTWHYPESDILQLEFVLPPGCFATVLVRELIDLVPVGQTDSSCVF
HHCCHHHEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNELELLGPRAYGEALGRAVLKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEECCCCCHHHHH
RRLARAAGVQLRTVSYAGLKDRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSGRHKR
HHHHHHHCCEEEEEEECCCHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHCCHHHH
KLQRGAHAANGFTLRLTQLDADKDALNQRLETIARQGIPNYFGAQRFGYQGGNLGEARDY
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHH
AARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWQKAQVGDLLAFTDSRSFFPAGV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCCC
DECSDPRLAILDLHPTGPQWGEGPSPAGGATAALENTVADDESVLRDWLVRAGMEHERRI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
LRLPIGRLTWHYPESDILQLEFVLPPGCFATVLVRELIDLVPVGQTDSSCVF
HHCCHHHEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA