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The map label for this gene is dapL [H]

Identifier: 66044588

GI number: 66044588

Start: 1518114

End: 1519307

Strand: Reverse

Name: dapL [H]

Synonym: Psyr_1340

Alternate gene names: 66044588

Gene position: 1519307-1518114 (Counterclockwise)

Preceding gene: 66044589

Following gene: 66044587

Centisome position: 24.93

GC content: 61.39

Gene sequence:

>1194_bases
ATGAATAACGCCATGCAACTGCTTCAGCCTTACCCTTTCGAGAAGCTGCGCGCCTTGCTGGCCGGCGTGACACCCAACCC
GGAAAAGCGTCCGGTAGCACTGTCCATCGGCGAACCGAAGCACCGCTCTCCCGATTTCGTTGCCAAAGCACTGGCAGACA
ACCTCGATCAGATGGCGGTTTACCCGACCACGCTGGGTATTCCTGCGCTGCGCGAAGCCATTGCCGGCTGGTGCAGCCGT
CGATTCGGCGTGCCACAGGGCTGGATCGATCCGGCGCGCAATGTATTACCGGTCAACGGCACGCGCGAAGCGCTGTTCGC
CTTCACCCAGACCGTAGTCAATCGCAGTGATGACGGCCTGGTGATCAGCCCGAATCCGTTTTACCAGATCTATGAAGGCG
CCGCGTTTCTGGCCGGAGCCCAACCGCACTACCTGCCCTGCCTGAGCGATAACGGGTTCAATCCCGATTTCGATGCCGTC
AGCCCGGACATCTGGAAGCGTTGCCAGATCCTCTTTCTGTGCTCACCAGGCAACCCGACCGGGGCGCTGATTCCGGTTGA
AACCCTGAAAAAGCTCATCGCCCTGGCCGACGAACATGACTTTGTCATTGCTGCGGACGAGTGCTACAGCGAGCTGTACT
TCGATGAGCAGACCCCGCCGCCGGGCCTGCTCAGCGCCTGCGTCGAGCTGGGCCGCGAGGATTTCAAACGCTGCGTGGTC
TTCCACAGCCTGTCCAAGCGCTCCAATCTGCCGGGCCTGCGCTCAGGTTTTGTGGCGGGTGACGCCCAGATCCTCAAGGC
CTTCCTGCTGTATCGCACCTATCACGGCTGCGCCATGCCGGTTCAGACTCAACTGGCCAGCATCGCCGCCTGGAATGATG
AGGAGCACGTACGCGCCAACCGTGATCTGTACCGGGAAAAGTTCGCTGCGGTGCTCGACATCCTGACCCCGGTGCTCGAC
GTTCAACGCCCGGACGGCGGCTTTTACCTGTGGCCGAACGTCGGTACCGATGACGCTGCATTTTGCCGCGATCTGTTCGT
CGATCAGCACGTCACTGCAGTACCGGGCTCGTACCTTTCCCGCGAAGTGGATGGCGTCAACCCTGGCGCAGGCCGGGTGC
GTCTTGCGCTCGTGGCCCCGTTGGCCGAATGCATCGAAGCGGCCGAACGTATCCGCGCATTCCTGAGCAAGTAA

Upstream 100 bases:

>100_bases
ACTGAGCGTCAACTCAGAGCCGGGCAACGATTTGCGGATCAGCATATGAATACTCGGCCATACGAATCGACTCAACGCAG
CTCATTGAGGAACACGTTCC

Downstream 100 bases:

>100_bases
AAGCCGAATCCAAAAAAATCGCCCCGCCGCATGCAATGTGCGGCGGGGTAATTAGTTACCACCTCCAGCCCCCTGCGTGA
ACGTACCCTCACCCTTCATT

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNNAMQLLQPYPFEKLRALLAGVTPNPEKRPVALSIGEPKHRSPDFVAKALADNLDQMAVYPTTLGIPALREAIAGWCSR
RFGVPQGWIDPARNVLPVNGTREALFAFTQTVVNRSDDGLVISPNPFYQIYEGAAFLAGAQPHYLPCLSDNGFNPDFDAV
SPDIWKRCQILFLCSPGNPTGALIPVETLKKLIALADEHDFVIAADECYSELYFDEQTPPPGLLSACVELGREDFKRCVV
FHSLSKRSNLPGLRSGFVAGDAQILKAFLLYRTYHGCAMPVQTQLASIAAWNDEEHVRANRDLYREKFAAVLDILTPVLD
VQRPDGGFYLWPNVGTDDAAFCRDLFVDQHVTAVPGSYLSREVDGVNPGAGRVRLALVAPLAECIEAAERIRAFLSK

Sequences:

>Translated_397_residues
MNNAMQLLQPYPFEKLRALLAGVTPNPEKRPVALSIGEPKHRSPDFVAKALADNLDQMAVYPTTLGIPALREAIAGWCSR
RFGVPQGWIDPARNVLPVNGTREALFAFTQTVVNRSDDGLVISPNPFYQIYEGAAFLAGAQPHYLPCLSDNGFNPDFDAV
SPDIWKRCQILFLCSPGNPTGALIPVETLKKLIALADEHDFVIAADECYSELYFDEQTPPPGLLSACVELGREDFKRCVV
FHSLSKRSNLPGLRSGFVAGDAQILKAFLLYRTYHGCAMPVQTQLASIAAWNDEEHVRANRDLYREKFAAVLDILTPVLD
VQRPDGGFYLWPNVGTDDAAFCRDLFVDQHVTAVPGSYLSREVDGVNPGAGRVRLALVAPLAECIEAAERIRAFLSK
>Mature_397_residues
MNNAMQLLQPYPFEKLRALLAGVTPNPEKRPVALSIGEPKHRSPDFVAKALADNLDQMAVYPTTLGIPALREAIAGWCSR
RFGVPQGWIDPARNVLPVNGTREALFAFTQTVVNRSDDGLVISPNPFYQIYEGAAFLAGAQPHYLPCLSDNGFNPDFDAV
SPDIWKRCQILFLCSPGNPTGALIPVETLKKLIALADEHDFVIAADECYSELYFDEQTPPPGLLSACVELGREDFKRCVV
FHSLSKRSNLPGLRSGFVAGDAQILKAFLLYRTYHGCAMPVQTQLASIAAWNDEEHVRANRDLYREKFAAVLDILTPVLD
VQRPDGGFYLWPNVGTDDAAFCRDLFVDQHVTAVPGSYLSREVDGVNPGAGRVRLALVAPLAECIEAAERIRAFLSK

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=301, Percent_Identity=26.2458471760797, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI169881279, Length=301, Percent_Identity=26.2458471760797, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4507369, Length=417, Percent_Identity=24.4604316546763, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI56713256, Length=337, Percent_Identity=22.8486646884273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56713254, Length=337, Percent_Identity=22.8486646884273, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=26.8929503916449, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=26.6490765171504, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788627, Length=357, Percent_Identity=25.2100840336134, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790797, Length=316, Percent_Identity=24.3670886075949, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=400, Percent_Identity=24.75, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=421, Percent_Identity=24.7030878859857, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=421, Percent_Identity=24.7030878859857, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI18859735, Length=398, Percent_Identity=25.6281407035176, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43687; Mature: 43687

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNAMQLLQPYPFEKLRALLAGVTPNPEKRPVALSIGEPKHRSPDFVAKALADNLDQMAV
CCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCHHHEEE
YPTTLGIPALREAIAGWCSRRFGVPQGWIDPARNVLPVNGTREALFAFTQTVVNRSDDGL
CCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCE
VISPNPFYQIYEGAAFLAGAQPHYLPCLSDNGFNPDFDAVSPDIWKRCQILFLCSPGNPT
EECCCCCHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCHHHHCCEEEEEEECCCCCC
GALIPVETLKKLIALADEHDFVIAADECYSELYFDEQTPPPGLLSACVELGREDFKRCVV
CCEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHH
FHSLSKRSNLPGLRSGFVAGDAQILKAFLLYRTYHGCAMPVQTQLASIAAWNDEEHVRAN
HHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
RDLYREKFAAVLDILTPVLDVQRPDGGFYLWPNVGTDDAAFCRDLFVDQHVTAVPGSYLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHCCCHHHH
REVDGVNPGAGRVRLALVAPLAECIEAAERIRAFLSK
HHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNAMQLLQPYPFEKLRALLAGVTPNPEKRPVALSIGEPKHRSPDFVAKALADNLDQMAV
CCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCHHHEEE
YPTTLGIPALREAIAGWCSRRFGVPQGWIDPARNVLPVNGTREALFAFTQTVVNRSDDGL
CCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCE
VISPNPFYQIYEGAAFLAGAQPHYLPCLSDNGFNPDFDAVSPDIWKRCQILFLCSPGNPT
EECCCCCHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCHHHHCCEEEEEEECCCCCC
GALIPVETLKKLIALADEHDFVIAADECYSELYFDEQTPPPGLLSACVELGREDFKRCVV
CCEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHH
FHSLSKRSNLPGLRSGFVAGDAQILKAFLLYRTYHGCAMPVQTQLASIAAWNDEEHVRAN
HHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
RDLYREKFAAVLDILTPVLDVQRPDGGFYLWPNVGTDDAAFCRDLFVDQHVTAVPGSYLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHCCCHHHH
REVDGVNPGAGRVRLALVAPLAECIEAAERIRAFLSK
HHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA