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The map label for this gene is yhjE [H]

Identifier: 66044526

GI number: 66044526

Start: 1443602

End: 1444972

Strand: Reverse

Name: yhjE [H]

Synonym: Psyr_1278

Alternate gene names: 66044526

Gene position: 1444972-1443602 (Counterclockwise)

Preceding gene: 66044527

Following gene: 66044520

Centisome position: 23.71

GC content: 62.95

Gene sequence:

>1371_bases
ATGCACGCTTGCCGGAATACGGTCGATGCCGACCGGCGAGTCGACTGTCAGGAAATCCGCATGACCAGCACCCCGCTCTC
TCGCGAAGATCACGACGCGCACGCAAAGCCGGTGAATTCGACGACCCGCGTCGCCACGGCCAGCTTTATCGGCACGGCCA
TCGAGTTCTACGACTTTTACGTGTATGCCACCGCCGCCGCCCTGGTGATCGGTCCGGTATTCTTTCCACAGACCTCGGGC
ACCGCCCAGATGCTGTCGTCATTTCTGACCTTCGGCATCGCCTTTCTCGCTCGCCCTCTGGGGTCGGCGCTGTTCGGTCA
CTTCGGTGACCGGATCGGGCGCAAGTCGACCCTGGTGGCCTCGCTGCTGTTGATGGGGATCTGCACCACGCTGATCGGCG
TATTGCCCGGCTACGCGACGATCGGGGCGTGGGCGCCGATTCTGTTGTGTGTGCTGCGTTTCGGTCAGGGGCTTGGCCTG
GGTGGCGAATGGGGTGGCGCGGCGCTACTGGCGACCGAGAATGCCCCGAAAGGCAAGCGCGCCTGGTTCGGCATGTTTCC
GCAACTGGGCCCTTCGATCGGCTTTCTTGCCGCCAACGGCCTGTTTCTGGCGCTGGCCATGACCCTCGATGACGAGCAGT
TCCGCGCGTGGGGCTGGCGGATTCCATTTCTGCTGAGCGCCGTACTGGTCATGGTCGGGCTGTACGTGCGCCTGAAGCTG
GAAGAGACGCCCGTGTTCGCCAAGGCCATGGCTCGCCACCAACGGGTCAGCCTGCCCATCGTGGAAACCTTCAGCCAGCA
CTGGAAACCCATGCTGCTCGGTGCGGCTTCGATGGTGGTCTGCTACGCGCTGTTTTATATCTCGACGGTGTTCTCGTTGA
GCTACGGCGTGGCCACGCTGGGCTATACCCGTGAAACGTTCCTGGGGTTGTTGTGCTTTGCGGTGCTGTTCATGGCAGCG
GCCACACCACTGGCCGCATTGGCGAGCGATCGCTTCGGGCGCAAGCCGGTGCTGATTGCGGGAGGCGTGCTGGCGATCCT
GTCAGGTTTTACCATGGAGCCACTGTTGACCCACGGCAGCACCTGGGCTGTGGCGCTGTTTCTGTGCATCGAACTGTTTC
TGATGGGCATCACGTTCGCCCCGATGGGCGCACTGCTACCGGAACTGTTCCCGACACAGGTTCGCTACACCGGCGCATCG
GCGGCCTACAACCTGGGCGGAATCGTCGGAGCGTCGGTCGCCCCCTTCTTCGCCCAGAAACTGGTGGCGATGGGTGGCCT
GAGCTGGGTGGGCGGGTATGTGTCTGCTGCAGCGCTGATCAGCGTGCTGGCGGTGTTGAGCCTGAAAGAGACGAGAGATA
GGGAGCTTTGA

Upstream 100 bases:

>100_bases
TTTCAAATAGCTGTCTGCGTTCAAATAGATTCCTGAACCGCCCTTGCCTCTCGACCCATTCGGGTTACTCTGCTCGACGC
CGCACCCACAATCACAATAA

Downstream 100 bases:

>100_bases
GCTGCAAGCTGCAAGCTGCAAGAAGAAGCGTGGTGCTCTTTCTTGCAGCTTGAGCCTTGAGGCTTACCGCTGCGCCCCTA
CAGTTCTACGTTTACCGCCT

Product: citrate-proton symport

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MHACRNTVDADRRVDCQEIRMTSTPLSREDHDAHAKPVNSTTRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSG
TAQMLSSFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGICTTLIGVLPGYATIGAWAPILLCVLRFGQGLGL
GGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLFLALAMTLDDEQFRAWGWRIPFLLSAVLVMVGLYVRLKL
EETPVFAKAMARHQRVSLPIVETFSQHWKPMLLGAASMVVCYALFYISTVFSLSYGVATLGYTRETFLGLLCFAVLFMAA
ATPLAALASDRFGRKPVLIAGGVLAILSGFTMEPLLTHGSTWAVALFLCIELFLMGITFAPMGALLPELFPTQVRYTGAS
AAYNLGGIVGASVAPFFAQKLVAMGGLSWVGGYVSAAALISVLAVLSLKETRDREL

Sequences:

>Translated_456_residues
MHACRNTVDADRRVDCQEIRMTSTPLSREDHDAHAKPVNSTTRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSG
TAQMLSSFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGICTTLIGVLPGYATIGAWAPILLCVLRFGQGLGL
GGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLFLALAMTLDDEQFRAWGWRIPFLLSAVLVMVGLYVRLKL
EETPVFAKAMARHQRVSLPIVETFSQHWKPMLLGAASMVVCYALFYISTVFSLSYGVATLGYTRETFLGLLCFAVLFMAA
ATPLAALASDRFGRKPVLIAGGVLAILSGFTMEPLLTHGSTWAVALFLCIELFLMGITFAPMGALLPELFPTQVRYTGAS
AAYNLGGIVGASVAPFFAQKLVAMGGLSWVGGYVSAAALISVLAVLSLKETRDREL
>Mature_456_residues
MHACRNTVDADRRVDCQEIRMTSTPLSREDHDAHAKPVNSTTRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSG
TAQMLSSFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGICTTLIGVLPGYATIGAWAPILLCVLRFGQGLGL
GGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLFLALAMTLDDEQFRAWGWRIPFLLSAVLVMVGLYVRLKL
EETPVFAKAMARHQRVSLPIVETFSQHWKPMLLGAASMVVCYALFYISTVFSLSYGVATLGYTRETFLGLLCFAVLFMAA
ATPLAALASDRFGRKPVLIAGGVLAILSGFTMEPLLTHGSTWAVALFLCIELFLMGITFAPMGALLPELFPTQVRYTGAS
AAYNLGGIVGASVAPFFAQKLVAMGGLSWVGGYVSAAALISVLAVLSLKETRDREL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789941, Length=435, Percent_Identity=54.2528735632184, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788292, Length=445, Percent_Identity=38.4269662921348, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1790550, Length=439, Percent_Identity=30.9794988610478, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788942, Length=429, Percent_Identity=31.2354312354312, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87082404, Length=346, Percent_Identity=26.5895953757225, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082231, Length=386, Percent_Identity=23.5751295336788, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48803; Mature: 48803

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHACRNTVDADRRVDCQEIRMTSTPLSREDHDAHAKPVNSTTRVATASFIGTAIEFYDFY
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VYATAAALVIGPVFFPQTSGTAQMLSSFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SLLLMGICTTLIGVLPGYATIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCH
AWFGMFPQLGPSIGFLAANGLFLALAMTLDDEQFRAWGWRIPFLLSAVLVMVGLYVRLKL
HHHHCCHHHCCCHHHHHHCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
EETPVFAKAMARHQRVSLPIVETFSQHWKPMLLGAASMVVCYALFYISTVFSLSYGVATL
CCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYTRETFLGLLCFAVLFMAAATPLAALASDRFGRKPVLIAGGVLAILSGFTMEPLLTHGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCCHHHHCCC
TWAVALFLCIELFLMGITFAPMGALLPELFPTQVRYTGASAAYNLGGIVGASVAPFFAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCHHHHHHHHHHHHH
LVAMGGLSWVGGYVSAAALISVLAVLSLKETRDREL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHACRNTVDADRRVDCQEIRMTSTPLSREDHDAHAKPVNSTTRVATASFIGTAIEFYDFY
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VYATAAALVIGPVFFPQTSGTAQMLSSFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SLLLMGICTTLIGVLPGYATIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCH
AWFGMFPQLGPSIGFLAANGLFLALAMTLDDEQFRAWGWRIPFLLSAVLVMVGLYVRLKL
HHHHCCHHHCCCHHHHHHCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
EETPVFAKAMARHQRVSLPIVETFSQHWKPMLLGAASMVVCYALFYISTVFSLSYGVATL
CCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYTRETFLGLLCFAVLFMAAATPLAALASDRFGRKPVLIAGGVLAILSGFTMEPLLTHGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCCHHHHCCC
TWAVALFLCIELFLMGITFAPMGALLPELFPTQVRYTGASAAYNLGGIVGASVAPFFAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCHHHHHHHHHHHHH
LVAMGGLSWVGGYVSAAALISVLAVLSLKETRDREL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]