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The map label for this gene is pleC [H]

Identifier: 66044351

GI number: 66044351

Start: 1244685

End: 1246415

Strand: Reverse

Name: pleC [H]

Synonym: Psyr_1100

Alternate gene names: 66044351

Gene position: 1246415-1244685 (Counterclockwise)

Preceding gene: 66044352

Following gene: 66044350

Centisome position: 20.45

GC content: 60.49

Gene sequence:

>1731_bases
ATGCCAACCTCGCCAGTGGACCGCCCGCTTGTCGACGCTCAGTCTCGCGCTGAAAAAATCGTCGAATCTCGCCGTCAGAA
AATCCTTCTCAAGACCGGCGCGCTGCAGGACGCAATTTTCAACAGCGCCTACTTCTCCAGCATCGCAACCGATGAGCACG
GCGTTATCCAGATATTCAATGTCGGCGCCGAACGGATGCTCGGCTATCACTCCGAAGACGTGGTCGACAAGATCACACCT
GCGGACATCTCCGACCCCGCCGAGCTCATCATCCGCGCGGCGGCCCTCAGCCATGAACTCAACACGCCCATCACGCCGGG
TTTCGAAGCCCTGGTATTCAAGGCTTCGCGCGGCATCGAAGACATCTACGAACTGACCTACATCCGCAAGGATGGCAGCC
GCCTGTCGGCCATGGTCTCGGTCACGTCACTGCGCGACAGCGCCGAAACCATCATCGGTTATCTGCTGATCGGCACCGAC
AACACCGCGCGCAAGCAGGAGGAAGAAGCTCAGGCCTTGCTCGATCAGCGCTTGCGGGACCAACAGTTCTATACCCGCTC
ACTGATCGAGTCGAACATCGATGCGCTGATGATGACCGACCCGCAAGGCATCATTTCCGACGTCAACAAGCAGATGATGG
CGCTGACCGGGCGCACCCGCGACGAATTGATCGGCGCGCCCTGCAAGAACTTCTTCACCGACCCGGCGAGTGCCGATGCC
GCCATCAAGCGCGTGCTCAGCGAGCACAAGGTCAGTGACTACGAACTCACCGTGCGCGCCTACGACGGCACTGAAACCGT
GGTGTCCTACAACGCCGCGACCTTTCATGACCGTGACCGCAAGCTCAAGGGTGTCTTCGCCGCGGCCCGCGACGTGACCG
AGCGCAAGCGTTTCGAGCGAACGCTGGAAGAAAAGAATATCGAGCTGGAACACGCCAGCCACATGAAGTCCGAGTTTCTT
GCCACCATGTCGCACGAGCTGCGCACCCCGCTCAACGCCGTGATCGGTTTCTCCGAGGCACTCAGGGACGGCATGGTCGG
CGACATGACCGATGCCCAGCGACGCTACATAGGCGATATCTTCAACAGCGGCCAGCACCTGCTGTCGCTGATCAATGACA
TCCTCGACCTGTCCAAGGTCGAGGCCGGCATGATGACGCTGGAGCTCGAGTCGGTCGATCTGGACGAACTGCTGAGCAAC
AGCCTGCTGATCGTGCGTGAGCAAGCCGCCCTGCAACACATTCAGCTGAAACTGGAAACAGAGGCCGAATTCGGTGAGCT
TGAGCTCGATCGACGCAAGACCAAGCAGATCGTCTACAACCTGCTGGCCAACGCCGTGAAATTCAGCGAGCCCGGTGGCT
GGGTGACGCTGGCGGTGCGATTGGTGCCGGCTTCCCAGGCGGGTCTTATCGATGGCGACTGGCCGACCTACGGGTTTGCG
CTTGCGTCCGGTGACTGTGAGCAGTTTCTGGAACTGAGTGTCAGCGACACCGGAATCGGCATCGCCCAAAGCGACATGAA
CAAGCTGTTCAAGGCGTTCAGCCAGATCGACAGCGGCCTGGCACGCAAATTCGAGGGCACCGGACTGGGTCTTGCGATGG
TCAAGCAACTGACCGAACTTCACGGCGGCTGCGTCGCGGTCGCCAGCGTGAAGGACCTCGGCGCACGCTTCGTGGTCTGG
CTGCCCATCCGCTCACCTGAATCAGCGGAGGCGCGATGGCCCAGATCCTGA

Upstream 100 bases:

>100_bases
CTGGTATCGTCCATGAACCTCTTATCATCCATTTGAATGGATGTCCGTAGTGTGATTACGGCCGTAATGGCAAAAAGGTC
AGGTAGTACCGGGAAGTCAT

Downstream 100 bases:

>100_bases
TCATTGAAGACAATGCGGCGAACATGCGTCTGGCAGAGCTATTGCTGACCAGCGCCGGGCACACTGTGCTGTCGGCCGTC
GATGCCGAAACCGGCCTGAA

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MPTSPVDRPLVDAQSRAEKIVESRRQKILLKTGALQDAIFNSAYFSSIATDEHGVIQIFNVGAERMLGYHSEDVVDKITP
ADISDPAELIIRAAALSHELNTPITPGFEALVFKASRGIEDIYELTYIRKDGSRLSAMVSVTSLRDSAETIIGYLLIGTD
NTARKQEEEAQALLDQRLRDQQFYTRSLIESNIDALMMTDPQGIISDVNKQMMALTGRTRDELIGAPCKNFFTDPASADA
AIKRVLSEHKVSDYELTVRAYDGTETVVSYNAATFHDRDRKLKGVFAAARDVTERKRFERTLEEKNIELEHASHMKSEFL
ATMSHELRTPLNAVIGFSEALRDGMVGDMTDAQRRYIGDIFNSGQHLLSLINDILDLSKVEAGMMTLELESVDLDELLSN
SLLIVREQAALQHIQLKLETEAEFGELELDRRKTKQIVYNLLANAVKFSEPGGWVTLAVRLVPASQAGLIDGDWPTYGFA
LASGDCEQFLELSVSDTGIGIAQSDMNKLFKAFSQIDSGLARKFEGTGLGLAMVKQLTELHGGCVAVASVKDLGARFVVW
LPIRSPESAEARWPRS

Sequences:

>Translated_576_residues
MPTSPVDRPLVDAQSRAEKIVESRRQKILLKTGALQDAIFNSAYFSSIATDEHGVIQIFNVGAERMLGYHSEDVVDKITP
ADISDPAELIIRAAALSHELNTPITPGFEALVFKASRGIEDIYELTYIRKDGSRLSAMVSVTSLRDSAETIIGYLLIGTD
NTARKQEEEAQALLDQRLRDQQFYTRSLIESNIDALMMTDPQGIISDVNKQMMALTGRTRDELIGAPCKNFFTDPASADA
AIKRVLSEHKVSDYELTVRAYDGTETVVSYNAATFHDRDRKLKGVFAAARDVTERKRFERTLEEKNIELEHASHMKSEFL
ATMSHELRTPLNAVIGFSEALRDGMVGDMTDAQRRYIGDIFNSGQHLLSLINDILDLSKVEAGMMTLELESVDLDELLSN
SLLIVREQAALQHIQLKLETEAEFGELELDRRKTKQIVYNLLANAVKFSEPGGWVTLAVRLVPASQAGLIDGDWPTYGFA
LASGDCEQFLELSVSDTGIGIAQSDMNKLFKAFSQIDSGLARKFEGTGLGLAMVKQLTELHGGCVAVASVKDLGARFVVW
LPIRSPESAEARWPRS
>Mature_575_residues
PTSPVDRPLVDAQSRAEKIVESRRQKILLKTGALQDAIFNSAYFSSIATDEHGVIQIFNVGAERMLGYHSEDVVDKITPA
DISDPAELIIRAAALSHELNTPITPGFEALVFKASRGIEDIYELTYIRKDGSRLSAMVSVTSLRDSAETIIGYLLIGTDN
TARKQEEEAQALLDQRLRDQQFYTRSLIESNIDALMMTDPQGIISDVNKQMMALTGRTRDELIGAPCKNFFTDPASADAA
IKRVLSEHKVSDYELTVRAYDGTETVVSYNAATFHDRDRKLKGVFAAARDVTERKRFERTLEEKNIELEHASHMKSEFLA
TMSHELRTPLNAVIGFSEALRDGMVGDMTDAQRRYIGDIFNSGQHLLSLINDILDLSKVEAGMMTLELESVDLDELLSNS
LLIVREQAALQHIQLKLETEAEFGELELDRRKTKQIVYNLLANAVKFSEPGGWVTLAVRLVPASQAGLIDGDWPTYGFAL
ASGDCEQFLELSVSDTGIGIAQSDMNKLFKAFSQIDSGLARKFEGTGLGLAMVKQLTELHGGCVAVASVKDLGARFVVWL
PIRSPESAEARWPRS

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=410, Percent_Identity=30.2439024390244, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI145693157, Length=293, Percent_Identity=33.4470989761092, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789149, Length=270, Percent_Identity=34.0740740740741, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788713, Length=276, Percent_Identity=32.9710144927536, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=32.6923076923077, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788549, Length=392, Percent_Identity=24.234693877551, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=26.7175572519084, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=25.7950530035336, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=259, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=267, Percent_Identity=23.2209737827715, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=23.1075697211155, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=251, Percent_Identity=24.7011952191235, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=26.6949152542373, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63740; Mature: 63609

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSPVDRPLVDAQSRAEKIVESRRQKILLKTGALQDAIFNSAYFSSIATDEHGVIQIFN
CCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEE
VGAERMLGYHSEDVVDKITPADISDPAELIIRAAALSHELNTPITPGFEALVFKASRGIE
CCHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHH
DIYELTYIRKDGSRLSAMVSVTSLRDSAETIIGYLLIGTDNTARKQEEEAQALLDQRLRD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QQFYTRSLIESNIDALMMTDPQGIISDVNKQMMALTGRTRDELIGAPCKNFFTDPASADA
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHCCCCCCHHH
AIKRVLSEHKVSDYELTVRAYDGTETVVSYNAATFHDRDRKLKGVFAAARDVTERKRFER
HHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
TLEEKNIELEHASHMKSEFLATMSHELRTPLNAVIGFSEALRDGMVGDMTDAQRRYIGDI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FNSGQHLLSLINDILDLSKVEAGMMTLELESVDLDELLSNSLLIVREQAALQHIQLKLET
HHCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHCCCEEEEEHHHHHHHHEEEEEC
EAEFGELELDRRKTKQIVYNLLANAVKFSEPGGWVTLAVRLVPASQAGLIDGDWPTYGFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEE
LASGDCEQFLELSVSDTGIGIAQSDMNKLFKAFSQIDSGLARKFEGTGLGLAMVKQLTEL
EECCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGGCVAVASVKDLGARFVVWLPIRSPESAEARWPRS
CCCEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PTSPVDRPLVDAQSRAEKIVESRRQKILLKTGALQDAIFNSAYFSSIATDEHGVIQIFN
CCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEE
VGAERMLGYHSEDVVDKITPADISDPAELIIRAAALSHELNTPITPGFEALVFKASRGIE
CCHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHH
DIYELTYIRKDGSRLSAMVSVTSLRDSAETIIGYLLIGTDNTARKQEEEAQALLDQRLRD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QQFYTRSLIESNIDALMMTDPQGIISDVNKQMMALTGRTRDELIGAPCKNFFTDPASADA
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHCCCCCCHHH
AIKRVLSEHKVSDYELTVRAYDGTETVVSYNAATFHDRDRKLKGVFAAARDVTERKRFER
HHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
TLEEKNIELEHASHMKSEFLATMSHELRTPLNAVIGFSEALRDGMVGDMTDAQRRYIGDI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FNSGQHLLSLINDILDLSKVEAGMMTLELESVDLDELLSNSLLIVREQAALQHIQLKLET
HHCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHCCCEEEEEHHHHHHHHEEEEEC
EAEFGELELDRRKTKQIVYNLLANAVKFSEPGGWVTLAVRLVPASQAGLIDGDWPTYGFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEE
LASGDCEQFLELSVSDTGIGIAQSDMNKLFKAFSQIDSGLARKFEGTGLGLAMVKQLTEL
EECCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGGCVAVASVKDLGARFVVWLPIRSPESAEARWPRS
CCCEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]