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The map label for this gene is aaeR [H]

Identifier: 66044297

GI number: 66044297

Start: 1179211

End: 1180209

Strand: Reverse

Name: aaeR [H]

Synonym: Psyr_1044

Alternate gene names: 66044297

Gene position: 1180209-1179211 (Counterclockwise)

Preceding gene: 66044302

Following gene: 66044296

Centisome position: 19.37

GC content: 61.06

Gene sequence:

>999_bases
ATGCATCCGTTACTTCATGTCACAATTTGCCATCTACTCAGAGAAGTACCCATGGACACCCTGCAAAACATGCGTGCCTT
CAGCTGCGTGGCGCAAGCGGGCAGCTTCACTGCTGCCGCCGCCGTGCTGGATACCACCACCGCCAACGTCTCGCGTGCGG
TCTCCAACCTTGAAGCGCATTTACAGACGCGCCTGCTCAATCGCACCACCCGGCGCATTGCCCTCACCGAAGCAGGCAAG
CGTTATCTGTTGCGCTGCGAGCAGATTCTCGCCTCGGTGGAAGAAGCCGAGGCCGAAGCCAGCGACGCTCATGCCCGCCC
GGCCGGGCAGCTCAAGATGCATTCGATGCCGGGCGTCGGCCAGCATTATGTGATCGACGCCATTGCCCGTTACCGGCGCA
ACCACCCGGACGTCGCGTTCGACCTGACCATGACCCACCGCGTGCCGGACTTGCTGGAAGAAGGCTATGACGTGTCGATC
GTGCTCGCCAGCGAACTGGCCGACTCGGGCTTTGTGTCTCAGCGCCTGGGCATTACCTACAGCATCGTGTGCGCGTCCCC
CGAGTACGTGAAAACCTTCGGCATGGCCCACAAGCCTGCCGACCTGCTGAATCATGCGTGCCTGCGTCTGGTGAGCCCGG
TGTTCCCGTTGGACAAATGGCTGTTCGATGGCCCGGAAGGTCAGGAGATGGTCACCATCAACAGCTCGCCGCTGCTGGTC
AACTCTGCGGATGCGATGAAGACCGCGATTTCCAGCGGCATGGGGGTCGGCATCCTGCCGATCTACTCGGCGATCGAGGG
GCTGCGCAACGGCACCCTGGTGCGCGTGTTGTCCGATTACCGCTCGCAAGAGCTGAACCTGTACGCCATCTACCCGTCCC
GCCAGTATCTGGATGCAAAGATCAGAACCTGGGTTGAATACCTGCGCGGTTCGTTGCCGGAAATTCTCGCAGCCGACGAA
GCCGATCTGCATGTGCAGGCGCTCAAGTCATCGTACTGA

Upstream 100 bases:

>100_bases
TTGAATGGCGGCGATTCTAGGCGGCGCTCGATGCGGCGATAAGCAGGGAGATTTGTGAATCTTTGTTACTGAAACGGCGA
TAATCCTTTGGTCTGGATAC

Downstream 100 bases:

>100_bases
CATCGTACAACTGCAAAAAGCGGCTGCCAAAGAGCGGGGAGGAATGTTAGCGTGCTACTCATTCAACCGCTCGAGAGTGA
CTGCCCAATGAAAAAAACCG

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MHPLLHVTICHLLREVPMDTLQNMRAFSCVAQAGSFTAAAAVLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGK
RYLLRCEQILASVEEAEAEASDAHARPAGQLKMHSMPGVGQHYVIDAIARYRRNHPDVAFDLTMTHRVPDLLEEGYDVSI
VLASELADSGFVSQRLGITYSIVCASPEYVKTFGMAHKPADLLNHACLRLVSPVFPLDKWLFDGPEGQEMVTINSSPLLV
NSADAMKTAISSGMGVGILPIYSAIEGLRNGTLVRVLSDYRSQELNLYAIYPSRQYLDAKIRTWVEYLRGSLPEILAADE
ADLHVQALKSSY

Sequences:

>Translated_332_residues
MHPLLHVTICHLLREVPMDTLQNMRAFSCVAQAGSFTAAAAVLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGK
RYLLRCEQILASVEEAEAEASDAHARPAGQLKMHSMPGVGQHYVIDAIARYRRNHPDVAFDLTMTHRVPDLLEEGYDVSI
VLASELADSGFVSQRLGITYSIVCASPEYVKTFGMAHKPADLLNHACLRLVSPVFPLDKWLFDGPEGQEMVTINSSPLLV
NSADAMKTAISSGMGVGILPIYSAIEGLRNGTLVRVLSDYRSQELNLYAIYPSRQYLDAKIRTWVEYLRGSLPEILAADE
ADLHVQALKSSY
>Mature_332_residues
MHPLLHVTICHLLREVPMDTLQNMRAFSCVAQAGSFTAAAAVLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGK
RYLLRCEQILASVEEAEAEASDAHARPAGQLKMHSMPGVGQHYVIDAIARYRRNHPDVAFDLTMTHRVPDLLEEGYDVSI
VLASELADSGFVSQRLGITYSIVCASPEYVKTFGMAHKPADLLNHACLRLVSPVFPLDKWLFDGPEGQEMVTINSSPLLV
NSADAMKTAISSGMGVGILPIYSAIEGLRNGTLVRVLSDYRSQELNLYAIYPSRQYLDAKIRTWVEYLRGSLPEILAADE
ADLHVQALKSSY

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=30.8724832214765, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=30.3921568627451, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=31.2925170068027, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=32.1917808219178, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=27.4914089347079, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.8194444444444, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=26.1904761904762, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786448, Length=299, Percent_Identity=22.742474916388, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=259, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=25.3472222222222, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693105, Length=118, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=286, Percent_Identity=22.027972027972, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=30.8943089430894, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36577; Mature: 36577

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPLLHVTICHLLREVPMDTLQNMRAFSCVAQAGSFTAAAAVLDTTTANVSRAVSNLEAH
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQTRLLNRTTRRIALTEAGKRYLLRCEQILASVEEAEAEASDAHARPAGQLKMHSMPGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCC
QHYVIDAIARYRRNHPDVAFDLTMTHRVPDLLEEGYDVSIVLASELADSGFVSQRLGITY
HHHHHHHHHHHHCCCCCEEEEEEEHHHCHHHHHCCCCEEEEEECHHCCCCCHHHHCCCEE
SIVCASPEYVKTFGMAHKPADLLNHACLRLVSPVFPLDKWLFDGPEGQEMVTINSSPLLV
EEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCEEE
NSADAMKTAISSGMGVGILPIYSAIEGLRNGTLVRVLSDYRSQELNLYAIYPSRQYLDAK
ECHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IRTWVEYLRGSLPEILAADEADLHVQALKSSY
HHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MHPLLHVTICHLLREVPMDTLQNMRAFSCVAQAGSFTAAAAVLDTTTANVSRAVSNLEAH
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQTRLLNRTTRRIALTEAGKRYLLRCEQILASVEEAEAEASDAHARPAGQLKMHSMPGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCC
QHYVIDAIARYRRNHPDVAFDLTMTHRVPDLLEEGYDVSIVLASELADSGFVSQRLGITY
HHHHHHHHHHHHCCCCCEEEEEEEHHHCHHHHHCCCCEEEEEECHHCCCCCHHHHCCCEE
SIVCASPEYVKTFGMAHKPADLLNHACLRLVSPVFPLDKWLFDGPEGQEMVTINSSPLLV
EEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCEEE
NSADAMKTAISSGMGVGILPIYSAIEGLRNGTLVRVLSDYRSQELNLYAIYPSRQYLDAK
ECHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IRTWVEYLRGSLPEILAADEADLHVQALKSSY
HHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]