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The map label for this gene is wecB [H]

Identifier: 66044285

GI number: 66044285

Start: 1165785

End: 1167035

Strand: Reverse

Name: wecB [H]

Synonym: Psyr_1032

Alternate gene names: 66044285

Gene position: 1167035-1165785 (Counterclockwise)

Preceding gene: 66044286

Following gene: 66044284

Centisome position: 19.15

GC content: 61.47

Gene sequence:

>1251_bases
ATGGCTGGTCTGCACCCCAGAATGAAGGTCCTTTCCATTTTCGGTACTCGTCCGGAGGCCATCAAAATGGCTCCTCTGGT
CAGAGCACTGGCTGCAGAGCCGGGTATCGACTCAAGAATCTGCATTACCGGGCAGCATCAAAGCATGCTGCAACAGGTGC
TGGACATGTTCGAGCTCAAAGCCGACTACAGCCTTGATGTGATGCGCCCGGATCAGACGCTGAACTCGCTGACCGCTGCG
CTTTACGCGGCGATCGACCCGATTCTGGACGAGATGAAACCGGACAGGGTGCTGGTTCACGGCGACACCACATCAGCAAT
GGTGGCGGCCATGTCGGCCTTTCATCGCCGGATCCCCATCGGCCACGTCGAAGCAGGTCTGCGCACCGGTGACATCCGTC
AGCCATGGCCTGAAGAGATGAACCGTCGTTGCATCGATCTGATTTCCGATCACCTGTTCGCCCCCACCGCCGAGTCGCGC
CGCAACGTGCTGGGCGAGCGCCTGCAGGGTATCTCGTTCGTGACCGGCAACACCGTGATCGACGCCCTGCACCTGACGGC
ACAGCGAATCGACAGCAATCGCCAACTGCGCCATGCACTTGATCGCCAGTTTTCGTTCCTGGTGCCCGAGCGCCGGGTGT
TGGTGGTGACCGGGCATCGTCGCGAGAACTTCGGCGACGGCTTCCTGAACATCTGCAAGGCGCTGGGCGAACTGGCCAGA
CGCGATGACATACAGATCGTTTACCCGGTGCACCTGAATCCCAATGTACTTGGGCCGGTGACCGAGCACCTGGGCGATCT
GCCCAACGTGCACCTGATCAAGCCGCTGGACTACCTGTCGTTCGTGCGCCTGATGCAACGCGCTCACGTCATCCTCACCG
ATTCCGGTGGCGTGCAGGAAGAAGCGCCGTCGCTGGGCAAACCGGTATTGGTCATGCGCGATGTCACCGAGCGCCCGGAA
GCGGTCGCGGCGGGCACTGTGCGCCTGGTGGGCACCGAGACGGACGCCATCATTCGCGGTGTGAACGCCCTGTTTGACGA
TGATGCGCTGTGGCAGAACGCCTCCCGTGCAGCCAACCCCTATGGCGACGGCAAAGCCAGTTCACGGATCGTCGATGCCC
TGATGGGCCGTCCGGTGGATGAGTTTGTCGCCGAGCTGCCGCGTCAGCGCCAGGACCCGGTGGACAGACACCTGGATACA
CGAATCAAGCCCCAGCATGAACATGCAGAGTTGCGCTCGATGGCCAGTTAG

Upstream 100 bases:

>100_bases
ATCTTTCCGCCCGAGAAACTCATCAACTCGCAAGCTGACCACGCTGCTCTCAGTCTGGTTTTTGCTGCCGTGCGACGCGC
TCAGGGCGCGGGAGGAAATA

Downstream 100 bases:

>100_bases
CCAAAAGGACGCGCAGGTAGCGCAAACGAACCCCAAAAAAATCCGCAGGAAGCAGTCCGCAAACGATACGGGCACCCGGT
TCAGACCGAGTGCCCGAAAA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MAGLHPRMKVLSIFGTRPEAIKMAPLVRALAAEPGIDSRICITGQHQSMLQQVLDMFELKADYSLDVMRPDQTLNSLTAA
LYAAIDPILDEMKPDRVLVHGDTTSAMVAAMSAFHRRIPIGHVEAGLRTGDIRQPWPEEMNRRCIDLISDHLFAPTAESR
RNVLGERLQGISFVTGNTVIDALHLTAQRIDSNRQLRHALDRQFSFLVPERRVLVVTGHRRENFGDGFLNICKALGELAR
RDDIQIVYPVHLNPNVLGPVTEHLGDLPNVHLIKPLDYLSFVRLMQRAHVILTDSGGVQEEAPSLGKPVLVMRDVTERPE
AVAAGTVRLVGTETDAIIRGVNALFDDDALWQNASRAANPYGDGKASSRIVDALMGRPVDEFVAELPRQRQDPVDRHLDT
RIKPQHEHAELRSMAS

Sequences:

>Translated_416_residues
MAGLHPRMKVLSIFGTRPEAIKMAPLVRALAAEPGIDSRICITGQHQSMLQQVLDMFELKADYSLDVMRPDQTLNSLTAA
LYAAIDPILDEMKPDRVLVHGDTTSAMVAAMSAFHRRIPIGHVEAGLRTGDIRQPWPEEMNRRCIDLISDHLFAPTAESR
RNVLGERLQGISFVTGNTVIDALHLTAQRIDSNRQLRHALDRQFSFLVPERRVLVVTGHRRENFGDGFLNICKALGELAR
RDDIQIVYPVHLNPNVLGPVTEHLGDLPNVHLIKPLDYLSFVRLMQRAHVILTDSGGVQEEAPSLGKPVLVMRDVTERPE
AVAAGTVRLVGTETDAIIRGVNALFDDDALWQNASRAANPYGDGKASSRIVDALMGRPVDEFVAELPRQRQDPVDRHLDT
RIKPQHEHAELRSMAS
>Mature_415_residues
AGLHPRMKVLSIFGTRPEAIKMAPLVRALAAEPGIDSRICITGQHQSMLQQVLDMFELKADYSLDVMRPDQTLNSLTAAL
YAAIDPILDEMKPDRVLVHGDTTSAMVAAMSAFHRRIPIGHVEAGLRTGDIRQPWPEEMNRRCIDLISDHLFAPTAESRR
NVLGERLQGISFVTGNTVIDALHLTAQRIDSNRQLRHALDRQFSFLVPERRVLVVTGHRRENFGDGFLNICKALGELARR
DDIQIVYPVHLNPNVLGPVTEHLGDLPNVHLIKPLDYLSFVRLMQRAHVILTDSGGVQEEAPSLGKPVLVMRDVTERPEA
VAAGTVRLVGTETDAIIRGVNALFDDDALWQNASRAANPYGDGKASSRIVDALMGRPVDEFVAELPRQRQDPVDRHLDTR
IKPQHEHAELRSMAS

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=56.0975609756098, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 46268; Mature: 46137

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLHPRMKVLSIFGTRPEAIKMAPLVRALAAEPGIDSRICITGQHQSMLQQVLDMFELK
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
ADYSLDVMRPDQTLNSLTAALYAAIDPILDEMKPDRVLVHGDTTSAMVAAMSAFHRRIPI
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCC
GHVEAGLRTGDIRQPWPEEMNRRCIDLISDHLFAPTAESRRNVLGERLQGISFVTGNTVI
CHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCHHH
DALHLTAQRIDSNRQLRHALDRQFSFLVPERRVLVVTGHRRENFGDGFLNICKALGELAR
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHC
RDDIQIVYPVHLNPNVLGPVTEHLGDLPNVHLIKPLDYLSFVRLMQRAHVILTDSGGVQE
CCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHCEEEEECCCCCCC
EAPSLGKPVLVMRDVTERPEAVAAGTVRLVGTETDAIIRGVNALFDDDALWQNASRAANP
CCCCCCCCEEEECCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHCCHHHHHCHHHCCCC
YGDGKASSRIVDALMGRPVDEFVAELPRQRQDPVDRHLDTRIKPQHEHAELRSMAS
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AGLHPRMKVLSIFGTRPEAIKMAPLVRALAAEPGIDSRICITGQHQSMLQQVLDMFELK
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
ADYSLDVMRPDQTLNSLTAALYAAIDPILDEMKPDRVLVHGDTTSAMVAAMSAFHRRIPI
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCC
GHVEAGLRTGDIRQPWPEEMNRRCIDLISDHLFAPTAESRRNVLGERLQGISFVTGNTVI
CHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCHHH
DALHLTAQRIDSNRQLRHALDRQFSFLVPERRVLVVTGHRRENFGDGFLNICKALGELAR
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHC
RDDIQIVYPVHLNPNVLGPVTEHLGDLPNVHLIKPLDYLSFVRLMQRAHVILTDSGGVQE
CCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHCEEEEECCCCCCC
EAPSLGKPVLVMRDVTERPEAVAAGTVRLVGTETDAIIRGVNALFDDDALWQNASRAANP
CCCCCCCCEEEECCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHCCHHHHHCHHHCCCC
YGDGKASSRIVDALMGRPVDEFVAELPRQRQDPVDRHLDTRIKPQHEHAELRSMAS
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]