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The map label for this gene is rhtC [H]

Identifier: 66044242

GI number: 66044242

Start: 1119347

End: 1119979

Strand: Direct

Name: rhtC [H]

Synonym: Psyr_0989

Alternate gene names: 66044242

Gene position: 1119347-1119979 (Clockwise)

Preceding gene: 66044241

Following gene: 66044243

Centisome position: 18.37

GC content: 63.98

Gene sequence:

>633_bases
ATGTACTGGGCAGAATTTCTTACCGTTGCGCTGATTCACTTGCTGGCGGTTGCCAGCCCCGGTCCGGATTTCGCGGTGGT
GGTGCGTGAAAGCGTCACTCATGGGCGCAAGGCAGGGACCTGGGCGGCGTTGGGCGTCGGCTCGGCGATCTTTCTGCATG
TGGGGTATTCGCTGCTGGGGATCGGGATTATCGTCTCCCAGTCCATCGTGCTGTTCAACGCGCTGAAATGGGCAGCCGCG
GCCTATCTACTGTACATCGGCATCAAGGCGTTGCGCGCCAAACCAGCCGCTGCAACGGGGGATACCGCCATCAAGGCCAC
TCCCGGCGAGCGCACGGCACGCGGTGCCTACATCAGCGGTTTCGTCACCAATGGCCTGAATCCCAAGGCGACGCTGTTCT
TCCTCTCGCTGTTCACCGTGGTGATCAATCCGCACACGCCACTGCTGGTGCAGGGCGGTTACGGCGTGTACCTCGCAGTG
GCGACGGCGGCGTGGTTCTGTCTGGTGGCGCGACTGTTCAGCCAGGCCCGGGTGCGCGCAGGATTCGCGCGCATGGGGCA
CTGGTTCGACCGGGCCATGGGCGGCGTGCTGATCGCGCTGGGCATCAAGCTGGCGCTGACCGAAGTGCGCTGA

Upstream 100 bases:

>100_bases
TTAGAGCACGCCCAGCGCCGCGCCAATGCTGGCATCTGTTGCGAAGACATCAGACAGCGTAATCTGCCGGGTCACACGTC
AACCCTCCAGGAGATCCCAC

Downstream 100 bases:

>100_bases
AACCTGAGTTCAGTACGCCGCTTACCGAACACATGCAGCAGTCCGGACGCCCCTTGCAGACAGCGCGGGGCGTCTCGAAA
AATCATCCCTTTTACTGATT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MYWAEFLTVALIHLLAVASPGPDFAVVVRESVTHGRKAGTWAALGVGSAIFLHVGYSLLGIGIIVSQSIVLFNALKWAAA
AYLLYIGIKALRAKPAAATGDTAIKATPGERTARGAYISGFVTNGLNPKATLFFLSLFTVVINPHTPLLVQGGYGVYLAV
ATAAWFCLVARLFSQARVRAGFARMGHWFDRAMGGVLIALGIKLALTEVR

Sequences:

>Translated_210_residues
MYWAEFLTVALIHLLAVASPGPDFAVVVRESVTHGRKAGTWAALGVGSAIFLHVGYSLLGIGIIVSQSIVLFNALKWAAA
AYLLYIGIKALRAKPAAATGDTAIKATPGERTARGAYISGFVTNGLNPKATLFFLSLFTVVINPHTPLLVQGGYGVYLAV
ATAAWFCLVARLFSQARVRAGFARMGHWFDRAMGGVLIALGIKLALTEVR
>Mature_210_residues
MYWAEFLTVALIHLLAVASPGPDFAVVVRESVTHGRKAGTWAALGVGSAIFLHVGYSLLGIGIIVSQSIVLFNALKWAAA
AYLLYIGIKALRAKPAAATGDTAIKATPGERTARGAYISGFVTNGLNPKATLFFLSLFTVVINPHTPLLVQGGYGVYLAV
ATAAWFCLVARLFSQARVRAGFARMGHWFDRAMGGVLIALGIKLALTEVR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=30.0970873786408, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786522, Length=203, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI48994979, Length=150, Percent_Identity=29.3333333333333, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788099, Length=150, Percent_Identity=30.6666666666667, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22275; Mature: 22275

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWAEFLTVALIHLLAVASPGPDFAVVVRESVTHGRKAGTWAALGVGSAIFLHVGYSLLG
CHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHH
IGIIVSQSIVLFNALKWAAAAYLLYIGIKALRAKPAAATGDTAIKATPGERTARGAYISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEH
FVTNGLNPKATLFFLSLFTVVINPHTPLLVQGGYGVYLAVATAAWFCLVARLFSQARVRA
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GFARMGHWFDRAMGGVLIALGIKLALTEVR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MYWAEFLTVALIHLLAVASPGPDFAVVVRESVTHGRKAGTWAALGVGSAIFLHVGYSLLG
CHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHH
IGIIVSQSIVLFNALKWAAAAYLLYIGIKALRAKPAAATGDTAIKATPGERTARGAYISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEH
FVTNGLNPKATLFFLSLFTVVINPHTPLLVQGGYGVYLAVATAAWFCLVARLFSQARVRA
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GFARMGHWFDRAMGGVLIALGIKLALTEVR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]