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The map label for this gene is ipk [H]

Identifier: 66044198

GI number: 66044198

Start: 1080200

End: 1081048

Strand: Reverse

Name: ipk [H]

Synonym: Psyr_0945

Alternate gene names: 66044198

Gene position: 1081048-1080200 (Counterclockwise)

Preceding gene: 66044199

Following gene: 66044197

Centisome position: 17.74

GC content: 54.3

Gene sequence:

>849_bases
ATGAGCACGCCACAACTGGTTTTGCCTGCCCCGGCAAAACTCAACCTCATGCTGCACATTCTCGGACGTCGTCCTGACGG
TTATCACGAACTGCAGACGCTGTTTCAGTTTCTCGATTACGGCGACGAACTGGGTTTTAGCGTTCGCGAAGATGGCGAGA
TTCACCTGCAGACCGACGTTCCCGGTGTCCCGCATGACAGTAACCTGATCGTCAAAGCCGCCCGTGCCCTGCAACAACAG
TCCGGTTGTACACTGGGCATGGACATCTGGCTGGAAAAACGCCTGCCCATGGGTGGCGGTATCGGCGGCGGCAGCTCGGA
TGCAGCGACCACCCTGCTGGCCCTGAATCATTTATGGCAGCTCGGCTGGGATGAGGATCGTCTGGCGCAACTGGGGCTGA
CACTGGGCGCCGATGTACCGGTTTTCGTACGTGGACATGCCGCTTTTGCTGAGGGCGTCGGCGAAATTCTCACCCCGGTG
GACCCGGAAGAACCCTGGTATTTGGTGCTCGTCCCGCAAGTATCTGTAAGTACAGCAGAAATTTTTTCAGATCCGTTGTT
GACACGCGACACGCCGCCCATTAAAGTGCGCCCCGTTCCCAAGGGAAACAGTCGAAATGACTGTAAGGCGGTTGTAGAGA
GGCGTTACCCAGAAGTACGTAACGCTTTGAATTTGTTAGGTAAATTTACCGAAGCAAAATTAACCGGAACTGGAAGTTGT
GTGTTTGGGGCCTTCCCAAACAAAGCTGAAGCTGATAAAGTCTCGGCCCTTCTTACAGAGACCCTTACGGGGTTCGTAGC
GAAAGGAAGCAACATCTCGATGTTGCATCGCAAGCTGCAAATTCTGTAG

Upstream 100 bases:

>100_bases
ACGGCTATTGGCTGCCAGAGCGCGTCAAGCTGCACGGGCAGGATCTGGATGTCACGCTGGTCATCAAGGACTGGCAGCCT
CGCAAACTGGGGCAATGAGC

Downstream 100 bases:

>100_bases
CAGGAATTGAGTGCCAGGCACTCGATTGATTCAATACAGGGGCGTCGCCAAGCGGTAAGGCAGCAGGTTTTGATCCTGCC
ATGCGTTGGTTCGAATCCAG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSTPQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFSVREDGEIHLQTDVPGVPHDSNLIVKAARALQQQ
SGCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQLGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPV
DPEEPWYLVLVPQVSVSTAEIFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGKFTEAKLTGTGSC
VFGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL

Sequences:

>Translated_282_residues
MSTPQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFSVREDGEIHLQTDVPGVPHDSNLIVKAARALQQQ
SGCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQLGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPV
DPEEPWYLVLVPQVSVSTAEIFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGKFTEAKLTGTGSC
VFGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL
>Mature_281_residues
STPQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFSVREDGEIHLQTDVPGVPHDSNLIVKAARALQQQS
GCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQLGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPVD
PEEPWYLVLVPQVSVSTAEIFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGKFTEAKLTGTGSCV
FGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=277, Percent_Identity=56.6787003610108, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30608; Mature: 30476

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFSVREDGEIHLQTDV
CCCCCEEECCCCHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHCCCEECCCCEEEEEECC
PGVPHDSNLIVKAARALQQQSGCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQ
CCCCCCCHHHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPVDPEEPWYLVLVPQVSVSTAE
CCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHH
IFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGKFTEAKLTGTGSC
HHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCE
VFGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
STPQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFSVREDGEIHLQTDV
CCCCEEECCCCHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHCCCEECCCCEEEEEECC
PGVPHDSNLIVKAARALQQQSGCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQ
CCCCCCCHHHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPVDPEEPWYLVLVPQVSVSTAE
CCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHH
IFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGKFTEAKLTGTGSC
HHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCE
VFGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA