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The map label for this gene is hlyB [H]

Identifier: 66044115

GI number: 66044115

Start: 978915

End: 980591

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_0860

Alternate gene names: 66044115

Gene position: 980591-978915 (Counterclockwise)

Preceding gene: 66044116

Following gene: 66044113

Centisome position: 16.09

GC content: 61.12

Gene sequence:

>1677_bases
GTGAAAAGATTTCTGCCTCGTTTCCTACGTCGGCAAGCCACAACGCCAACACTCTTGCGCCGCTTCAAAATCACGCTGCG
CCTGGTGATCTGCTTCGCTATAACCTCCCTGCTGATGGTCGCGCTTGGCGTATTCTGCCTGTTGCAGATGCAGGCTATCC
GCACCCAGGGCGAGGCGGTCGAGAGCGGCGCCCTGCCCAGTATCGCCACCGCCGATGCCATCGCTATCGGCCTGGTCAAA
CTGCGCAGCGAAACCACCCGTCTGATCGCCAACGCCGACGATCCGGGTGCCGTTATCAACAGCAAGATCAATGTCGAACA
ACTCAGGAACGAGGTCGAGAAAGGCTTCTCGGAATACCTGGCGCGTGTTCAGTCGGGCACTGAGCATGACTCGATTGTCG
CGTTGCAGGATGCCTACAAGGCCTTCATGCCCGGCTTGCAGGATCAGATCGCGCTGATCGAGCAGAACAAGCTGGACGAG
GCCAGGACGCTGGCCAACACCGTGCTCTCGCTGCAGGGTGACCTGATGGACATGCAGGTGCAGCTGTTGCGCGAACTGAA
CACGCAGAGTGCGGCCGCCGCTGTAGAGGCCGCAGGTGCCAGCTATGAACAGACCCGGATCATCGCGCTGAGCGCCATCG
GCCTGGTTCTGGTACTGACCCTGTTGCTGGCTTGGCGCCTGAGCGTCAGCATCATCCATCCGGTGCGGCAGGCCTTACAC
ATCGCCAGCACCATTGCCGATGGTGACCTGAGCGAACACCCGATACCGGACGGCAAGGACGAGACCGCACAATTATTGAT
CACGCTCGGGCGCATGCGTACCAACCTGCACAGTACGATCGACCAGATCTACGCAGCGGCGACGCAGTTGTCGCAGTCGG
TTCAGGAAATGGGCAGCATCGCCGAAGCCAGTGCGCTCAATCTGCAGCTGCAGAACACTGAAATCGAGCAGGCCGCTGTC
GCGGTCAATCAGATGAGCCAGGCGGCCATCGAAGTGGCAGGCAACGCCAGCAATACCGTGACCGAATCGGAGGCGTCAAC
CCGGGCGGCGGCACAAGGGCAGGAAAAGCTGTCGGCAACCATTCTGTCGATCAAGGCGTTGACCGAGAATGTGCTGGATT
CGTCGCATCAGGCTGAAGGGCTGGCCGAACGTACCCAGAGCATCAGCAGCATCCTCGATGTGATTCGCGCAATCGCCAAT
CAGACCAACCTGCTGGCGCTGAACGCGGCTATCGAAGCGGCTCGTGCAGGCGAAGCCGGGCGAGGCTTTGCCGTGGTGGC
CGATGAAGTCCGCTCACTGGCGCAGCGCACCAGTGCATCCACCGCGGAAATCGAAGGGCTGATCAGCGGCGTGCAGCAAA
GCACCCAACAAACCGCCAGCTCGCTGCGCCACACGGCGACGCAGGCCAATCTGACAATGGAACAGGCCGCCTCGACCGGC
GAAGCCTTGCAAGTGATCATCCAGTCAACCGCCACCATCAACGACCGCAACCTGCTGATTGCCAGTGCCGCAGAGCAGCA
GGCCCAGGTGGCGACTGAGGTGGACCGCAACCTGAGCAGTATTCGCGACCTGTCCAGCCAGACCGCATCGGGCGCGCAGC
AGACCACCGTCGCGAGTAACGCACTGTCGATGCTGGCGACTGATCTGAACCTGATGGTGCAGCGTTTCGTGCTGTGA

Upstream 100 bases:

>100_bases
GCTGCCTACCCATCATTCAGTAGATGTCATAAAGACATCACACAATTGCCCTATAAACGGCTCTCCGAGAAGGTCCGTGT
GTTTATAGGGGTTGTGTGCC

Downstream 100 bases:

>100_bases
TGGGTTGAAACTCGCCAGCCAGCCTGCGCCACAGGCTGGCTGACGATAAGCAGCTGTCAGTCCTGCGGACGCAGACGGTA
CTGCGGGGGCAATTGCTCGA

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MKRFLPRFLRRQATTPTLLRRFKITLRLVICFAITSLLMVALGVFCLLQMQAIRTQGEAVESGALPSIATADAIAIGLVK
LRSETTRLIANADDPGAVINSKINVEQLRNEVEKGFSEYLARVQSGTEHDSIVALQDAYKAFMPGLQDQIALIEQNKLDE
ARTLANTVLSLQGDLMDMQVQLLRELNTQSAAAAVEAAGASYEQTRIIALSAIGLVLVLTLLLAWRLSVSIIHPVRQALH
IASTIADGDLSEHPIPDGKDETAQLLITLGRMRTNLHSTIDQIYAAATQLSQSVQEMGSIAEASALNLQLQNTEIEQAAV
AVNQMSQAAIEVAGNASNTVTESEASTRAAAQGQEKLSATILSIKALTENVLDSSHQAEGLAERTQSISSILDVIRAIAN
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTSASTAEIEGLISGVQQSTQQTASSLRHTATQANLTMEQAASTG
EALQVIIQSTATINDRNLLIASAAEQQAQVATEVDRNLSSIRDLSSQTASGAQQTTVASNALSMLATDLNLMVQRFVL

Sequences:

>Translated_558_residues
MKRFLPRFLRRQATTPTLLRRFKITLRLVICFAITSLLMVALGVFCLLQMQAIRTQGEAVESGALPSIATADAIAIGLVK
LRSETTRLIANADDPGAVINSKINVEQLRNEVEKGFSEYLARVQSGTEHDSIVALQDAYKAFMPGLQDQIALIEQNKLDE
ARTLANTVLSLQGDLMDMQVQLLRELNTQSAAAAVEAAGASYEQTRIIALSAIGLVLVLTLLLAWRLSVSIIHPVRQALH
IASTIADGDLSEHPIPDGKDETAQLLITLGRMRTNLHSTIDQIYAAATQLSQSVQEMGSIAEASALNLQLQNTEIEQAAV
AVNQMSQAAIEVAGNASNTVTESEASTRAAAQGQEKLSATILSIKALTENVLDSSHQAEGLAERTQSISSILDVIRAIAN
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTSASTAEIEGLISGVQQSTQQTASSLRHTATQANLTMEQAASTG
EALQVIIQSTATINDRNLLIASAAEQQAQVATEVDRNLSSIRDLSSQTASGAQQTTVASNALSMLATDLNLMVQRFVL
>Mature_558_residues
MKRFLPRFLRRQATTPTLLRRFKITLRLVICFAITSLLMVALGVFCLLQMQAIRTQGEAVESGALPSIATADAIAIGLVK
LRSETTRLIANADDPGAVINSKINVEQLRNEVEKGFSEYLARVQSGTEHDSIVALQDAYKAFMPGLQDQIALIEQNKLDE
ARTLANTVLSLQGDLMDMQVQLLRELNTQSAAAAVEAAGASYEQTRIIALSAIGLVLVLTLLLAWRLSVSIIHPVRQALH
IASTIADGDLSEHPIPDGKDETAQLLITLGRMRTNLHSTIDQIYAAATQLSQSVQEMGSIAEASALNLQLQNTEIEQAAV
AVNQMSQAAIEVAGNASNTVTESEASTRAAAQGQEKLSATILSIKALTENVLDSSHQAEGLAERTQSISSILDVIRAIAN
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTSASTAEIEGLISGVQQSTQQTASSLRHTATQANLTMEQAASTG
EALQVIIQSTATINDRNLLIASAAEQQAQVATEVDRNLSSIRDLSSQTASGAQQTTVASNALSMLATDLNLMVQRFVL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=473, Percent_Identity=27.906976744186, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788194, Length=459, Percent_Identity=30.2832244008715, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI2367378, Length=510, Percent_Identity=25.2941176470588, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788195, Length=293, Percent_Identity=30.7167235494881, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789453, Length=256, Percent_Identity=30.859375, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59478; Mature: 59478

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLPRFLRRQATTPTLLRRFKITLRLVICFAITSLLMVALGVFCLLQMQAIRTQGEAV
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ESGALPSIATADAIAIGLVKLRSETTRLIANADDPGAVINSKINVEQLRNEVEKGFSEYL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
ARVQSGTEHDSIVALQDAYKAFMPGLQDQIALIEQNKLDEARTLANTVLSLQGDLMDMQV
HHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHH
QLLRELNTQSAAAAVEAAGASYEQTRIIALSAIGLVLVLTLLLAWRLSVSIIHPVRQALH
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASTIADGDLSEHPIPDGKDETAQLLITLGRMRTNLHSTIDQIYAAATQLSQSVQEMGSI
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEASALNLQLQNTEIEQAAVAVNQMSQAAIEVAGNASNTVTESEASTRAAAQGQEKLSAT
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ILSIKALTENVLDSSHQAEGLAERTQSISSILDVIRAIANQTNLLALNAAIEAARAGEAG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCC
RGFAVVADEVRSLAQRTSASTAEIEGLISGVQQSTQQTASSLRHTATQANLTMEQAASTG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EALQVIIQSTATINDRNLLIASAAEQQAQVATEVDRNLSSIRDLSSQTASGAQQTTVASN
HHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALSMLATDLNLMVQRFVL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRFLPRFLRRQATTPTLLRRFKITLRLVICFAITSLLMVALGVFCLLQMQAIRTQGEAV
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ESGALPSIATADAIAIGLVKLRSETTRLIANADDPGAVINSKINVEQLRNEVEKGFSEYL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
ARVQSGTEHDSIVALQDAYKAFMPGLQDQIALIEQNKLDEARTLANTVLSLQGDLMDMQV
HHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHH
QLLRELNTQSAAAAVEAAGASYEQTRIIALSAIGLVLVLTLLLAWRLSVSIIHPVRQALH
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASTIADGDLSEHPIPDGKDETAQLLITLGRMRTNLHSTIDQIYAAATQLSQSVQEMGSI
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEASALNLQLQNTEIEQAAVAVNQMSQAAIEVAGNASNTVTESEASTRAAAQGQEKLSAT
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ILSIKALTENVLDSSHQAEGLAERTQSISSILDVIRAIANQTNLLALNAAIEAARAGEAG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCC
RGFAVVADEVRSLAQRTSASTAEIEGLISGVQQSTQQTASSLRHTATQANLTMEQAASTG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EALQVIIQSTATINDRNLLIASAAEQQAQVATEVDRNLSSIRDLSSQTASGAQQTTVASN
HHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALSMLATDLNLMVQRFVL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]